Check here for lab updates.
They worked with two post-docs in the lab, Rita and Valerie, to complete a summer research project.
Congratulations on great presentations!
Congratulations to Valerie on winning first place post-doc poster prize!
Beaver ML, Evans RC. (2025) Muscarinic receptor activation preferentially inhibits rebound in vulnerable dopaminergic neurons. J Neurosci 25 February 2025, e1443242025 https://doi.org/10.1523/JNEUROSCI.1443-24.2025
Huge Congratulations to Dr. Michel Fallah who successfully defended her dissertation!
https://open.spotify.com/episode/27MzlcEmw6cts4Z91aYGzH?si=AI1mJQpgRPuUilTnkrIn2A
Fallah M, Udobi KC, Swiatek AE, Scott CB, Evans RC. (2024) Inhibitory basal ganglia nuclei differentially innervate pedunculopontine nucleus subpopulations and evoke opposite motor and valence behaviors. eLife, https://doi.org/10.7554/eLife.102308.1
https://elifesciences.org/reviewed-preprints/102308
Megan presented a talk and Briana and Lindsey presented posters.
Congratulations to Lindsey for winning the 2nd place poster prize!
PSTR016.12 Board: C89 Saturday 10/5/24 1-5pm
Dr. Kenea Udobi – Detailing the time course of Parkinson’s disease cholinopathy: insights from a novel mouse model
PSTR173.04 Board: H40 Monday 10/7/24 8am-12pm
Dr. Valerie Lewitus – Sex-specific effects of aerobic exercise on motor performance and basal ganglia neural properties
PSTR173.23 Board: I19 Monday 10/7/24 8am-12pm
Michel Fallah – SNr and GPe inhibition of anatomically and genetically defined PPN subpopulations.
LBA005.010 Board: LBA91 Monday 10/7/24 8am-12pm
Briana Bernstein– The superior colliculus sends divergent excitatory and inhibitory inputs to the rostral and caudal PPN
This Fall, we have 3 new people in the lab!
Joel Walker Jr. joins us for the year as a Neuroscience Master's Student.
Celine Ertekin and Margaret "Greta" Sten both join us as rotating IPN students.
https://www.biorxiv.org/content/10.1101/2024.08.05.606694v1
Huge congratulations to MD/PhD candidate Michel Fallah for leading this project and to post-doc Dr. Kenea Udobi, previous undergraduate Aleksandra "Ola" Swiatek, and previous master's student Chelsea Scott!
Muscarinic receptor activation preferentially inhibits rebound in vulnerable dopaminergic neurons.
https://www.biorxiv.org/content/10.1101/2024.07.30.605819v1
Huge congratulations to PhD candidate Megan Beaver for leading this project and submitting her first first-author manuscript!
Valeria presented her first poster and Valerie presented a talk.
He patched his first cell!
Lindsey, Kenea, and Michel presented posters.
Next she is heading to medical school at the University of Virginia!
Chen RY, Evans RC. (2024) Comparing tonic and phasic dendritic calcium in cholinergic pedunculopontine neurons and dopaminergic substantia nigra neurons. Eur J Neurosci. 2024 Feb 21. doi: 10.1111/ejn.16281. PMID: 38383047.
Congratulations to Dr. Rita Yu-Tzu Chen for leading this project and on the publication of her first first-author paper.
Valeria Aleman contributed her artistic skills and drew the dragon!
Congratulations to Michel for first place oral presentation and Lindsey for third place poster prize!
We are happy to have them here!
Valerie patches her first cell in the lab!
https://www.biorxiv.org/content/10.1101/2023.08.28.555184v1
Comparing tonic and phasic calcium in the dendrites of vulnerable midbrain neurons.
Chen and Evans, 2023 BioRxiv
We're excited to have him here!
They both patched beautiful neurons yesterday!
Check out this really nice computational project from Dr. Dan Chapman.
https://link.springer.com/article/10.1007/s12021-023-09633-7
This grant funds us to use electrophysiology and fiber photometry to assess circuitry changes in a mouse model of cholinergic cell loss.
We're excited to work on this project!
January 2021
January 2023
Chelsea Scott presented her poster on exercise and PPN at the main SfN meeting and at the TPDA awardees poster session.
Michel Fallah presented her poster on the basal ganglia connectivity with the PPN at the main SfN meeting.
Megan Beaver presented her poster on the muscarinic modulation of dopaminergic neurons at the main SfN meeting.
Aleksandra Swiatek presented her poster on in vivo optogenetic stimulation of PPN inputs at the Faculty for Undergraduate Neuroscience (FUN) poster session.
Alex's poster won the 3rd place poster prize!
lab time!
She patched her first cell!
Evans RC. (2022) Dendritic involvement in inhibition and disinhibition of vulnerable dopaminergic neurons in healthy and pathological conditions. Neurobiology of Disease. 9 July 2022.
https://pubmed.ncbi.nlm.nih.gov/35820645/
Alex patched his first PPN cell!
Registration for the virtual BRAIN meeting is free and can be found here:
We're excited to have her here!
She's already patching cells on the new electrophysiology setup!
Our second electrophysiology rig and the two photon microscope are set up and almost ready to use!
They are both patching beautiful cells!
We had our first lab outing to say good bye. We'll miss her!