Entrepreneurial ecosystem building requires perseverance. The work is challenging and often ambiguous, and it can take 20 years to see concrete results. Many practitioners—including grassroots organizers and change agents within large institutions—operate without adequate training, funding, or recognition of their work as a professional endeavor. In this void, they must often rely on their instincts, personal support systems, and ad hoc revenue streams. While dedication powers many of them to continue, practitioners across the field are burning out. To sustain the work of ecosystem building, we must equip our practitioners for the long haul with a professional job description, training programs, ongoing peer support, and sustainable funding models. Together, we can ensure that ecosystem builders from all types of organizations and communities have the professional recognition and resources they need to nurture this work and give it the time it requires to achieve results.