Day 1
14:00–14:20 CET Berlin
08:00–08:20 am EDT Boston
Welcome and Introduction Epithelioid Sarcoma Digital Expert Panel 2021
Thomas Grünewald, Head of Dept. Translational Pediatric Sarcoma Research, German Cancer Research Center DKFZ / Hopp-Kindertumorzentrum (KiTZ) Heidelberg, Germany, Paolo Casali, Istituto Nazionale Tumori, Italy, Andrea Bolzicco, Orchestra per la Vita, Italy, Michael Wortmann, SMARCB1 e.V., Germany
14:20–15:40 CET Berlin
08:20–09:40 am EDT Boston
Presentations (10-15 min.) & Discussion (10-15 min.).
Moderation Thomas Grünewald
From Enzinger to WHO 2020, fifty years of epithelioid sarcoma diagnoses
Angelo Paolo Dei Tos, Istituto Nazionale Tumori, Italy
Epithelioid Sarcoma: Epidemiology and registry
Annalisa Trama, Istituto Nazionale dei Tumori, Milan, Italy
Natural history and prognostic of epithelioid sarcoma: what is known and what is left to know
Anna Maria Frezza, Istituto Nazionale dei Tumori, Milan, Italy
The proteomic landscape of SMARCB1-deficient sarcomas
Paul Huang, The Institute of Cancer Research, United Kingdom
Break 15:40–15:55 CET Berlin
09:40–09:55 am EDT Boston
15:55–16:55 CET Berlin
09:55–10:55 am EDT Boston
Presentations (10-15 min.) & Discussion (10-15 min.).
Moderation Paolo Casali
Functional and translational genomics of epithelioid sarcoma
Thomas Grünewald, Head of Dept. Translational Pediatric Sarcoma Research, German Cancer Research Center DKFZ / Hopp-Kindertumorzentrum (KiTZ) Heidelberg, Germany
Novel Pipeline for Precision Immunotherapy
Vincezo Cerullo, ImmunoViroTherapy Lab, University of Helsinki, Finland
Immunomodulation approach for Epithelioid Sarcoma
Javier Martin-Broto, MUsculoSkeletal Tumor Board of Excellence Sevilla (MUSTBE SEVILLA), Instituto de Biomedicina de Sevilla, Spain
Break 16:55–17:10 CET Berlin
10:55–11:10 EDT Boston
17:10–17:50 CET Berlin
11:10–11:50 am EDT Boston
Presentations (10-15 min.) & Discussion (10-15 min.).
Moderation Thomas Grünewald
Novel multitarget inhibitors in Epithelioid Sarcoma treatment: an in vitro preliminary study
Alessandro Sgambato, Centro di Riferimento Oncologico della Basilicata (CROB), Italy
May we target sarcoma metastasis with immunotherapy?
Antonio Perez-Martinez, Hospital La Paz Institute for Health Research (IdiPAZ), Spain
17:50–18:20 CET Berlin
11:50 am –12:20 pm EDT Boston
▪ Which questions are unresolved and need to be answered urgently (biology and therapy)?
▪ How can basic research and clinical research be linked? (knowledge transfer)
▪ Which other disciplines need to be involved?
18:20-19:00 CET Berlin
12:20–01:00 pm EDT Boston
Available Rooms with specific Topics:
▪ "Immunotherapy“ with Vincenzo Cerullo, University of Helsinki
▪ Further Rooms to be announced
End of Event 19:00 CET Berlin
01:00 pm EDT Boston
Day 2
14:00–14:20 CET Berlin
08:00–08:20 am EDT Boston
Paolo Casali, Director of the Medical Oncology Unit 2 at the Istituto Nazionale Tumori, Milan, Italy, Thomas Grünewald, Head of Dept. Translational Pediatric Sarcoma Research, German Cancer Research Center DKFZ / Hopp-Kindertumorzentrum (KiTZ) Heidelberg, Germany Andrea Bolzicco, Orchestra per la Vita, Italy, Michael Wortmann, SMARCB1 e.V., Germany
14:20–15:40 CET Berlin
08:15–09:40 am EDT Boston
Presentations (10-15 min.) & Discussion (10-15 min.).
Moderation Paolo Casali
Break 15:00–15:55 CET Berlin
09:40–09:55 am EDT Boston
15:55–17:15 CET Berlin
09:55–11:15 am EDT Boston
Presentations (10-15 min.) & Discussion (10-15 min.).
Moderation Thomas Grünewald
Break 17:15–17:30 CET Berlin
11:15–11:30 am EDT Boston
17:30–18:00 CET Berlin
11:30 am–12:00 pm EDT Boston
▪ How can basic research and clinical research be linked? (knowledge transfer)
▪ Which other disciplines need to be involved?
▪ Organization/coordination of research management
18:00–18:30 CET Berlin
12:00–12:30 pm EDT Boston
▪ Goal of regular meetings and knowledge exchange
▪ Tasks and goals result from the formulation of the future strategy
▪ Organization/coordination/financing
▪ Takeaway and Deliverables of EPS 2021 Meeting / Next Steps
18:30-19:00 CET Berlin
12:30–01:00 pm EDT Boston
Available Rooms with specific Topics:
▪ "Innovation and Technology for EPS Cures“ with Charles Keller, Children’s Cancer Therapy Development Institute
▪ Further Rooms to be announced
End of Event 18:30 CET Berlin
01:00 pm EDT Boston