PhD Candidate, Graduate School of Engineering Science, The University of Osaka, Japan
Deguchi Laboratory
JSPS Research Fellow (DC1)
What mechanics and dynamics are unique to living systems?
Coupling of Mechanics, Signaling & Structure; Turnover & Remodeling; Homeostasis, Adaptation & State Transitions
Our new preprint, “A time-delayed mechanochemical feedback model reconciles stable maintenance and dynamic remodeling of cell-matrix adhesions,” is now available on bioRxiv.
We show how time-delayed mechanochemical feedback can reconcile the dual features of cell-matrix adhesions: stable maintenance and dynamic remodeling.
https://doi.org/10.64898/2026.08.28.747716
Our paper, A systems-based analysis of feedback structure and characteristic timescales in turnover-mediated mechanical adaptation, has been published in the Journal of Theoretical Biology.
We investigate how feedback structure and characteristic timescales shape turnover-mediated mechanical adaptation in living systems.
https://doi.org/10.1016/j.jtbi.2026.112571
I participated in the 10th World Congress of Biomechanics (WCB2026), held in Vancouver, Canada, from July 11 to 15, 2026, and gave an oral presentation entitled “Chemomechanical Modeling of Time-Delayed Feedback in Cell–ECM Adhesion Regulation” in a session on cell–ECM interactions. I was also honored to receive a Student Bursary Award. My participation was supported by the Young Investigator International Activity Support Program of the MEXT Transformative Research Area (A), Multimodal ECM.
✅ Mechanobiology
✅ Physical Biology & Biophysics
✅ Theoretical Biology
✅ Biomechanics
✅ Active Matter
🇯🇵 Japanese
🇬🇧 🇺🇸 English