PhD Candidate, Graduate School of Engineering Science, The University of Osaka, Japan
Deguchi Laboratory
JSPS Research Fellow (DC1)
What mechanics and dynamics are unique to living systems?
Coupling of Mechanics, Signaling & Structure; Turnover & Remodeling; Homeostasis, Adaptation & State Transitions
Our paper is now published in Cellular and Molecular Bioengineering! Combining live-cell imaging with stochastic and reduced-order models, we examine how impaired actin polymerization promotes mechanical fragility of actin bundles under stretch.
https://doi.org/10.1007/s12195-026-00946-6
Our new preprint, “A time-delayed mechanochemical feedback model reconciles stable maintenance and dynamic remodeling of cell-matrix adhesions,” is now available on bioRxiv.
We show how time-delayed mechanochemical feedback can reconcile the dual features of cell-matrix adhesions: stable maintenance and dynamic remodeling.
https://doi.org/10.64898/2026.08.28.747716
Our paper, A systems-based analysis of feedback structure and characteristic timescales in turnover-mediated mechanical adaptation, has been published in the Journal of Theoretical Biology.
We investigate how feedback structure and characteristic timescales shape turnover-mediated mechanical adaptation in living systems.
https://doi.org/10.1016/j.jtbi.2026.112571
✅ Mechanobiology
✅ Physical Biology & Biophysics
✅ Theoretical Biology
✅ Biomechanics
✅ Active Matter
🇯🇵 Japanese
🇬🇧 🇺🇸 English