We derived vehicle flight performance requirements modeling current EMS infrastructure and the impact of cooperatively deployed UAVs. Using physics simulations, we built a UAV to meet these requirements. The design process included an evaluation of various path-planning methods given various speeds. This UAV doubles the EMS coverage area of Indiana in a six minute window. The vehicle navigates to a victim using a planned flight path with forward and downward collision sensors to prevent accidents, as well as a 4G-enabled companion computer for added reliability. A bystander retrieves Narcan from the payload dispenser, and follows video and audio instructions played by the vehicle. With the ability to rapidly reach far distances, autonomously land, and provide medication and instructions to bystanders, a fleet of these UAVs would provide EMS responses to areas where ambulances cannot reach quickly, improving the medical outcomes of overdose victims.