Integrative Auditory Lab
Mechanisms and Therapeutic Strategies for Hearing Loss
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Research Interests
Our research focuses on understanding the pathophysiological mechanisms of hearing loss, particularly cisplatin-induced ototoxicity, and developing strategies to protect auditory function. We investigate how systemic diseases, immune responses, and vascular barriers such as the blood–labyrinth barrier regulate cochlear homeostasis and contribute to hearing loss. In addition, we aim to develop advanced inner ear drug delivery systems for targeted protection and treatment of auditory disorders.
Our research focuses on understanding the pathophysiological mechanisms of hearing loss, particularly cisplatin-induced ototoxicity, and developing strategies to protect auditory function. We investigate how systemic diseases, immune responses, and vascular barriers such as the blood–labyrinth barrier regulate cochlear homeostasis and contribute to hearing loss. In addition, we aim to develop advanced inner ear drug delivery systems for targeted protection and treatment of auditory disorders.
Major research areas include:
Ototoxicity mechanisms, particularly cisplatin-induced cochlear hair cell damage and synaptic degeneration
Immune responses in the cochlea, including macrophage-mediated inflammation and immune cell activation
Systemic disease–associated hearing loss, with emphasis on metabolic disorders and systemic inflammation
Biomaterial-based drug delivery for the inner ear, focusing on targeted and sustained therapeutic strategies
Central neural mechanisms of hearing loss, including neural reorganization and cognitive decline
Join Us
Our lab welcomes highly motivated students and researchers interested in auditory neuroscience, hearing loss, and translational research. We offer opportunities for undergraduate, graduate, and postdoctoral training. We are always looking for passionate researchers to join our team.
Please contact us with your CV and a brief statement of interest at : parkyh@cnu.ac.kr
We look forward to hearing from you.
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