Selected Publications
Regmi, D., Shen, F., Stanic, A., Islam, M., Du, D.* "Effect of phospholipid liposomes on prion fragment (106-128) amyloid formation." BBA-Biomembranes 2023, 1865, 184199.
Islam, M., Argueta, E., Wojcikiewicz, E.P., Du, D.* "Effects of charged polyelectrolytes on amyloid fibril formation of a tau fragment." ACS Chem. Neurosci. 2022, 13, 3034-3043.
Shen, F., Regmi, D., Islam, M., Raja Somu, D., Merk, V., Du, D.* "Effects of zinc and carnosine on aggregation kinetics of amyloid-β40 peptide." Biochem. Biophys. Rep. 2022, 32, 101333.
Islam, M.,* Shen, F., Regmi, D., Petersen, K., Karim, M. R. U., Du, D.* "Tau liquid–liquid phase separation: at the crossroads of tau physiology and tauopathy." J. Cell. Physiol. 2022, 1-18.
Islam, M.,* Shen, F., Regmi, D., Du, D.* "Therapeutic strategies for tauopathies and drug repurposing as a potential approach." Biochem. Pharmacol. 2022, 198, 114979.
Singh, Y., Regmi, D., Ormaza, D., Ayyalasomayajula, R., Vela, N., Mundim, G., Du, D., Minond, D., and Cudic, M. "Mucin-Type O-Glycosylation Proximal to β-Secretase Cleavage Site Affects APP Processing and Aggregation Fate." Front. Chem. 2022, 10, 859822.
Morris, C., Kent, T. W., Shen, F., Wojcikiewicz, E. P., Du, D.* “Effects of the hydrophilic N-terminal region on Aβ-mediated membrane disruption.” J. Phys. Chem. B. 2021, 125, 7671-7678.
Torres, K. M., Delgado, A. S., Serrano, E. R., Falcon-Cruz, N. V., Melendez, A., Ramos, I., Du, D.*, Oyola, R.* “Gallium nanoparticles as novel inhibitors of Aβ40 aggregation.” Mater. Adv. 2021, 9, 5471-5478
Lantz, R., Busbee, B., Wojcikiewicz, E. P., Du, D.* “Flavonoids with Vicinal Hydroxyl Groups Inhibit Human Calcitonin Amyloid Formation.” Chem. Eur. J. 2020, 26, 13063-13071.
Lantz, R., Busbee, B., Wojcikiewicz, E. P., Du, D.* “Effects of disulfide bond and cholesterol derivatives on human calcitonin amyloid formation.” Biopolymers 2020, 111, e23343-23351
Li, H., Lantz, R., Du, D.* “Vibrational approach to the dynamics and structure of protein amyloids.” Molecules 2019, 24, 186-206.
He, Y., Huang, Z., Ma, Z., Yao, B., Liu, H., Hu, L., Zhao, Q., Yang, Q., Liu, D., Du, D. “Highly efficient photocatalytic performance and mechanism of α-ZnTcPc/g-C3N4 composites for methylene blue and tetracycline degradation under visible light irradiation.” Appl. Surf. Sci. 2019, 498, 143834-143846.
Liu, H., Lantz, R., Kent, T. W., Elbassal, E. A., Wojcikiewicz, E. P. & Du, D.* “Residue-Specific Dynamics and Local Environmental Changes in Aβ40 Oligomer and Fibril Formation.” Angew. Chem. Int. Ed., 2018, 57, 8017-8021.
Morris, C., Cupples S., Kent, T. W., Elbasssal, E. A., Wojcikiewicz, E. P., Yi, P.* & Du, D.* “N-terminal Charged Residues of Amyloid-β Peptide Modulate Amyloidogenesis and Interaction with Lipid Membrane.” Chem. Eur. J., 2018, 24, 9494-9498.
Rao, P. & Du, D. “In Silico Strategies to Design Small Molecules to Study Beta-Amyloid Aggregation.” Neuromethods, 2018, 132, 249-261.
Elbassal, E. A., Morris, C., Kent, T., Lantz, R., Wojcikiewicz, E. P. & Du, D.* “Gold Nanoparticles as a Probe for Amyloid-β Oligomer and Amyloid Formation.” J. Phys. Chem. C., 2017, 121, 20007-20015.
Elbassal, E. A., Liu, H., Morris, C., Wojcikiewicz, E. P. & Du, D.* “Effects of charged cholesterol derivatives on Aβ40 amyloid formation.” J. Phys. Chem. B., 2016, 120, 59-68.
Liu, H., Ojha, B., Morris, C., Jiang, M., Wojcikiewicz, E. P., Rao, P. P. & Du, D.* “Positively charged chitosan and N-trimethyl chitosan inhibit Aβ40 fibrillogenesis.” Biomacromolecules, 2015, 16, 2363-2373.
Liu, H., Lantz, R., Cosme, P., Rivera, N., Andino, C., Gonzalez, W. G., Terentis, A. C., Wojcikiewicz, E. P., Oyola, R., Miksovska, J. & Du, D.* “Site-specific dynamics of amyloid formation and fibrillar configuration of Aβ1-23 using an unnatural amino acid.” Chem. Commun. 2015, 51, 7000-7003.
Markiewicz, B. N., Oyola, R., Du, D.* & Gai, F.* “Aggregation gatekeeper and controlled assembly of Trpzip β-hairpins.” Biochemistry 2014, 53, 1146-1154.
Ojha, B., Liu, H., Dutta, S., Rao, P. P., Wojcikiewicz, W. P. & Du, D.* “Poly(4-styrenesulfonate) as an inhibitor of Abeta40 amyloid fibril formation.” J. Phys. Chem. B. 2013, 117, 13975-13984.
Xu, Y., Du, D.* & Oyola R.* “Infrared study of the stability and folding kinetics of a series of beta-hairpin peptides with a common NPDG turn.” J. Phys. Chem. B. 2011, 115, 15332-15338.
Du, D., Cohen, E., Kim, H., Simkovsky, R., Dillin, A. & Kelly, J. W. “A kinetic aggregation assay enabling sensitive and sensitive Abeta amyloid quantification in cells and tissues.” Biochemistry 2011, 50, 1607-1617.
Cohen, E., Du, D., Joyce, D., Kapernick, E. A., Volovik, Y., Kelly, J. W. & Dillin, A. “Temporal requirements of insulin/IGF-1 signaling for proteotoxicity protection.” Aging Cell 2010, 9, 126-134.
van Ham, T. J., Holmberg, M. A., van der Goot, A. T., Teuling, E., Garcia, M., Kim, H., Du, D., Thijssen, K. L., Wiersma, M., Burggraaff, R., van Bergeijk, P., van Rheenen, J., van Veluw, G. J., Hofstra, R. M. W., Rubinsztein, D. C. & Nollen, E. A. A. “Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.” Cell 2010, 142, 601-612.
Cohen, E., Paulsson, J. F., Blinder, P., Burstyn-Cohen, T., Du, D., Estepa, G., Adame, A., Pham, H. M., Holzenberger, M., Kelly, J. W., Masliah, E. & Dillin, A. “Reduced IGF-1 signaling delays proteotoxicity in mice.” Cell 2009, 139, 1157-1169.
Fuller, A., Du, D., Liu, F., Davoren, J. E., Kroon, G., Dyson, H. J., Powers, E. T., Wipf, P., Gruebele, M. & Kelly, J. W. “Evaluating beta-turn mimics as beta-sheet folding nucleators.” Proc. Natl. Acad. Sci. USA, 2009, 106, 11067-11072.
Liu, F., Du, D., Fuller, A., Davoren, J. E., Wipf, P., Kelly, J. W. & Gruebele, M. “An experimental survey of the transition between two-state and downhill protein folding scenarios.” Proc. Natl. Acad. Sci. USA 2008, 105, 2369-2374.
Du, D., Bunagan, M. R. & Gai, F. “The effect of charge-charge interactions on the kinetics of alpha-helix formation.” Biophys. J. 2007, 93, 4076-4082.
Du, D. & Gai, F. “Understanding the folding mechanism of helix-hairpin.” Biochemistry 2006, 45, 13131-13139.
Du, D., Tucker, M. J. & Gai, F. “Understanding the mechanism of beta-hairpin folding via F-value analysis.” Biochemistry 2006, 48, 2668-2678.
Du, D., Zhu, Y., Huang, C. Y. & Gai, F. “Understanding the key factors that control the rate of beta-hairpin folding.” Proc. Natl. Acad. Sci. USA 2004, 101, 15915-15920.