Down syndrome regression disorder (DSRD) is a rare condition seen in some people with Down syndrome. This condition has also been referred to as...
Down syndrome disintegrative disorder (DSDD)
Unexplained regression in Down syndrome (URDS)
Acute, developmental, or unexplained regression
Obsessional slowness
Acute neuropsychiatric disorder
Rapid clinical deterioration
Catatonia
Photo from National Society of Down Syndrome: https://www.ndss.org/about-down-syndrome/qa-for-kids/