PUBLICATIONS

Recent Publications

Baylis–Hillman adducts were conveniently transformed into α-carbolinone and α-carboline derivatives by monoalkylation of 2-nitrobenzylcyanide, imide formation/Friedel–Crafts cyclization, and treatment with Fe/AcOH in simple process is described. 

J Heterocyclic Chem, 2023, 60,957 

Dandamudi. V, Lenin, Payal Malvi 

https://doi.org/10.1002/jhet.4639 


A simple and efficient synthesis of (E)-5-arylylidene-3-((substituted-ind-2-en-1-one)methyl)-3-aryl piperidine-2,6-diones from Baylis-Hillman acetates via bis-alkylation of aryl acetonitriles followed by facile domino bis-cyclization involving C–C bond and C–N bond formation reactions are described 

Dandamudi. V, Lenin, Payal Malvi 

Tetrahedron, 2023, 145, 133603. 

https://doi.org/10.1016/j.tet.2023.133603

Synthesis of β-Aryl-γ-lactams and 2-Oxo-1,2-dihydroquinolines


Synfacts 2022; 18(06): 0612 

DOI: 10.1055/s-0041-1738346 

Contributor(s): Paul Richardson , Mihir Parikh (Pfizer) 

We successfully demonstrated two different reaction pathways for the synthesis of β-aryl-γ-lactam and 2-oxo-1,2-dihydroquinoline derivatives using β-nitrostyrenes. The reaction strategy involves the Michael addition followed by reduction and cyclization reactions. 

J Heterocyclic Chem. 2022, 59, 588.

https://doi.org/10.1002/jhet.4446 

Water Extract of Lemon (WEL) as a Promoter: Green and Regioselective Synthesis of Alkyl-4-(1H-indol-3 yl)-2-alkyl-4H-chromene-3-carboxylates Using 4H-chromenes andIndoles.

Vasantha R, Dandamudi V Lenin, L. Chandrashekhara Rao, and Nandigama Satish Kumar

Chemistry Select, 2020, 5, 14004.

 doi.org/10.1002/slct.202003542.

Facile Synthesis of Substituted Indenones and Piperidine-2,6-diones from theBaylis–Hillman Acetates

Deevi Basavaiah and Dandamudi V. Lenin

Eur. J. Org. Chem,

DOI: 10.1002/ejoc.201000739

The Baylis-Hillman Bromides as Versatile Synthons: A Facile One-Pot Synthesis of Indolizine and Benzofused Indolizine Frameworks.

Deevi Basavaiah, Badugu Devendhar, Dandamudi V. Lenin and Tummanapalli Satyanarayana

Synlett,

DOI: 10.1055/s-0028-1087533

A simple protocol for the synthesis of a piperidine-2,6-dione framework from Baylis–Hillman adducts

Deevi Basavaiah, Dandamudi V. Lenin and Badugu Devendhar 

TetrahedronLetters doi.org/10.1016/j.tetlet.2009.03.038 

The Baylis – Hillman Adducts as Valuable Source for One-Pot Multi-Step Synthesis: A Facile Synthesis of Substituted Piperidin-2-ones.

Deevi Basavaiah, Raju Jannapu Reddy, and Dandamudi V. Lenin

HelveticaChimicaActa,

doi.org/10.1002/hlca.200900352 

Synthesis of substituted maleimide derivatives using the Baylis–Hillman adducts

Current Science,

Deevi Basavaiah, Dandamudi V. Lenin and Gorre Veeraraghavaiah