Research Experience
RESEARCH EXPERIENCE ~
Ongoing Research Project [in Raidighi College]:
“Study of Sundarban honey from various botanical sources as a potential anti-microbial, anti-inflammatory, anti-oxidant and anti-cancer agent”
{funded by Department of Higher Education, Government of West Bengal}
Research Experience prior to joining Raidighi College :
Department of Life Science and Biotechnology, Jadavpur University, Kolkata, India
[ 5th Dec 2011- 4th April 2014]
Position: CSIR Senior Research Associate (Scientists’ pool)
Independent Research Projects
Project I: Title: Studies on Characterization of Interaction between the 60S Ribosome Biogenesis Factor eIF6 and Ca2+-dependent Calcineurin Phosphatase and the role of this interaction on 60S Ribosome Biogenesis in Mammalian Cells
Project II: Title: Study of eIF6 recycling in relation to Shwachman-Bodian-Diamond syndrome, an autosomal recessive disorder characterized by bone marrow failure and leukemia predisposition
Department of Medicine, Albert Einstein College of Medicine, New York, USA
[July 2008 – Nov 2010]
Position: Research Associate
PI: Prof. Sridhar Mani
Research Experience
Studied the role of Pregnane X receptor (PXR, an orphan nuclear receptor) in colon cancer
Studied post-translational modifications of human PXR
Initiated a project to generate a somatic cell knockout of human PXR gene
Developed a system of studying human colon cancer cells in three dimensional cultures
Department of Developmental and Molecular Biology,
Albert Einstein College of Medicine, New York, USA
[Aug 2006 – June 2008]
Position: Post Doctoral Research Associate
PI: Prof. Umadas Maitra
Research Experience
Studied phosphorylation and dephosphorylation-mediated regulation of eukaryotic translation initiation factor eIF6, an essential ribosome biogenesis factor, in yeast and mammalian cell culture
Department of Life Science and Biotechnology, Jadavpur University, Kolkata, India
[July 2005 – June 2006]
Position: Post Doctoral Fellow; Funded by DBT, Govt. of India
PI: Prof. Subrata Pal
co-PI: Prof. Chanchal DasGupta (C.U.)
Research Experience
Investigated the fourth step of protein translation, namely, disassembly of the post-termination complex, followed by ribosome recycling to enter a new round of translation
Department of Biophysics, Molecular Biology and Genetics, Calcutta University, Kolkata, India (presently, Department of Biophysics, Molecular Biology and Bioinformatics)
[Jan 2000 – June 2005]
Position: Ph.D. Fellow; Funded by CSIR, Govt. of India
PI: Prof. Chanchal DasGupta
Research Experience
PhD Project titled ‘Studies on interaction of tRNA and Unfolded Protein with Ribosome’