The asterisk (*) in the publication list indicates corresponding authorship
40. Anoop Arunagiri*, Emily Sontag*, Verena Kohler*, and Arunkumar Venkatesan*, Editorial: Cellular Contributors and Consequences of Protein Misfolding and Aggregation (2026), Front. Mol. Biosci. https://doi.org/10.3389/fmolb.2025.1759495
39. Anoop Arunagiri, Leena Haataja, Maroof Alam, Noah Gleason, Emma Mastroianni, Chao-Yin Cheng, Sami Bazzi Onton, Jeffrey Knupp, Ibrahim Metawea, Anis Hassan, Dennis Larkin, Deyu Fang, Billy Tsai, Ling Qi, and Peter Arvan, Limiting ER-associated degradation capacity triggers acute and chronic effects on insulin biosynthesis (2025), J Clin Invest. 2025. https://doi.org/10.1172/JCI187341 (in press)
38. Ambuja Navalkar*, Anoop Arunagiri*, Tovaria Kee, Kathigna Panchal, and Kathryn Dick, Protein Aggregates and Biomolecular Condensates: Implications for Human Health and Disease (2025), Front Mol Biosci 2025 Dec 2:12:1719678
37. Enrico Virgilio, Sylvia Tielens, Georgia Bonfield, Fang-Shin Nian, Toshiaki Sawatani, Chiara Vinci, Molly Govier, Hossam Montaser, Romane Lartigue, Anoop Arunagiri, Alexandrine Liboz, Flavia Natividade da Silva, Maria Lytrivi, Theodora Papadopoulou, Matthew N. Wakeling, James Russ-Silsby, Pamela Bowman, Matthew B. Johnson, Thomas W. Laver, Anthony Piron, Xiaoyan Yi, Federica Fantuzzi, Sirine Hendrickx, Mariana Igoillo-Esteve, Bruno J. Santacreu, Jananie Suntharesan, Radha Ghildiyal, Darshan G. Hegde, Nikhil Avnish Shah, Sezer Acar, Beyhan Özkaya Dönmez, Behzat Özkan, Fauzia Mohsin, Iman M. Talaat, Mohamed Tarek Abbas, Omar Saied Abbas, Hamed Ali Alghamdi, Nurgun Kandemir, Sarah E. Flanagan, Raphael Scharfmann, Peter Arvan, Matthieu Raoux, Laurent Nguyen, Andrew T. Hattersley, Miriam Cnop, and Elisa De Franco, Recessive TMEM167A variants cause neonatal diabetes, microcephaly and epilepsy syndrome (2025), J Clin Invest. 2025 Sep 9:e195756
36. Anoop Arunagiri*, Maroof Alam*, Erez Dror*, and Melkam A Kebede*, Editorial: Dietary and Nutrigenetic Contributors to Metabolic Syndrome (2025), Front Endocrinol (Lausanne). 2025 Jun 18:16:1632753
35. Anoop Arunagiri*, Insook Jang, Pamela Itkin-Ansari, Randal J Kaufman, and Peter Arvan*, Quantification of Folded and Misfolded Proinsulin Forms Using Nonreducing SDS-PAGE and Proinsulin-Specific Immunoblotting (2025), Bio-protocol 15(11): e5337
34. Srivastav Ranganathan* and Anoop Arunagiri*, The B22 dilemma: structural basis for conformational differences in proinsulin B-chain Arg22 mutants (2025), Biomolecules 2025, 15(4), 577
33. Parisima Zavarzadeh, Kathigna Panchal, Dylan Bishop, Elizabeth Gilbert, Mahi Trivedi, Tovaria Kee, Srivastav Ranganathan*, Anoop Arunagiri*, Exploring Proinsulin Proteostasis: Insights into Beta Cell Health and Diabetes (2025), Front Mol Biosci 2025 Mar 5:12:1554717
32. Parisima Ghaffarian Zavarzadeh, and Anoop Arunagiri*, Proinsulin Folding-Trafficking Relationship in Diabetes (2024), JoLS-Pub J. Life Sci. Vol. 1, No. 1, October 2024:1-5 (doi.org/10.36069/jols/20241001)
31. Anoop Arunagiri, Maroof Alam, Leena Haataja, Hassan Draz, Bashiyer Alasad, Praveen Samy, Nadeed Sadique, Yue Tong, Ying Cai, Hadis Shakeri, Federica Fantuzzi, Hazem Ibrahim, Insook Jang, Vaibhav Sidarala, Scott Soleimanpour, Leslie Satin, Timo Otonkoski, Miriam Cnop, Pamela Itkin-Ansari, Randal Kaufman, Ming Liu, and Peter Arvan, Proinsulin Folding and Trafficking Defects Trigger a Common Pathological Disturbance of Endoplasmic Reticulum Homeostasis (2024), Protein Sci. 2024; 33(4): e4949
30. Irina Zhang, Andrea Hermann, Juan Leon, Sivakumar Jeyarajan, Anoop Arunagiri, Peter Arvan, Patrick Gilon, Leslie Satin, ER stress increases expression of intracellular calcium channel RyR1 to modify Ca2+ homeostasis in pancreatic beta cells (2023), J Biol Chem 2023; 299(8):105065
29. Yu-Te Yeh, Chandan Sona, Xin Yan, Yunxiao Li, Adrija Pathak, Mark McDermott, Zhigang Xie, Liangwen Liu, Anoop Arunagiri, Yuting Wang, Amaury Cazenave-Gassiot, Adhideb Ghosh, Ferdinand von Meyenn, Sivarajan Kumarasamy, Sonia Najjar, Shiqi Jia, Markus Wenk, Alexis Traynor-Kaplan, Peter Arvan, Sebastian Barg, Vytas Bankaitis, and Matthew Poy, Restoration of PITPNA in Type 2 diabetic human islets reverses pancreatic beta-cell dysfunction (2023), Nat Commun 2023; 14(1):4250
28. Xiaoxi Xu, Anoop Arunagiri, Maroof Alam, Leena Haataja, Charles R. Evans, Ivy Zhao, Roberto Castro-Gutierrez, Holger Russ, Caroline Demangel, Ling Qi, Billy Tsai, Ming Liu, Peter Arvan, Nutrient-dependent fluctuation in β-cell proinsulin content (2023), J Biol Chem 2023; 299(7):104836
27. Xiaoxi Xu, Anoop Arunagiri, Leena Haataja, Maroof Alam, Shuhui Ji, Ling Qi, Billy Tsai, Ming Liu, and Peter Arvan. Proteasomal degradation of wild-type proinsulin in pancreatic beta cells (2022), J. Biol. Chem. (2022) 298(10) 102406
26. Yiping Mao, Jacob Schoenborn, Zhihong Wang, Xinqian Chen, Katy Matson, Ramkumar Mohan, Shungang Zhang, Xiaohu Tang, Anoop Arunagiri, Peter Arvan, Xiaoqing Tang, Transgenic overexpression of microRNA-30d in pancreatic beta-cells progressively regulates beta-cell function and identity (2022), Sci Rep 2022;12(1):11969
25. Manita Shakya, Surbhi Gahlot, Nicolle Martin, Anoop Arunagiri, Martin Martin, Peter Arvan, Malcolm J Low, Iris Lindberg. The G209R mutant mouse as a model for human PCSK1 polyendocrinopathy (2022), Endocrinology 2022; bqac024
24. Yu-Jie Chen, Jeffrey Knupp, Anoop Arunagiri, Leena Haataja, Peter Arvan, and Billy Tsai. PGRMC1 acts as a size-selective cargo receptor to drive ER-phagic clearance of mutant prohormones (2021), Nat Commun 12, 5991 (2021)
23. Maroof Alam, Anoop Arunagiri, Leena Haataja, Mauricio Torres, Dennis Larkin, John Kappler, Niyun Jin, Peter Arvan. Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes (2021), Diabetes 2021; 70(11): 2580-2594
22. Leena Haataja, Anoop Arunagiri, Anis Hassan, Kaitlin Regan, Billy Tsai, Balamurugan Dhayalan, Michael A. Weiss, Ming Liu, Peter Arvan. Distinct states of proinsulin misfolding in MIDY (2021), Cell Mol Life Sci 2021;78(16):6017-6031
21. Ming Liu, Yumeng Huang, Xiaoxi Xu, Xin Li, Maroof Alam, Anoop Arunagiri, Leena Haataja, Li Ding, Shusen Wang, Pamela Itkin-Ansari, Randal J. Kaufman, Billy Tsai, Ling Qi, and Peter Arvan. Normal and defective pathways in biogenesis and maintenance of the insulin storage pool (2021), J Clin Invest. 2021;131(2):e142240
20. Corey Cunningham, Jeffery Williams, Jeffery Knupp, Anoop Arunagiri, Peter Arvan, and Billy Tsai. Cells deploy a two-pronged strategy to rectify misfolded proinsulin aggregates (2019), Mol Cell. 2019 Aug 8; 75(3):442-456.e4
19. Anoop Arunagiri, Leena Haataja, Anita Pottekat, Fawnnie Pamenan, Soohyun Kim, Lori M Zeltser, Adrienne W Paton, James C Paton, Billy Tsai, Pamela Itkin-Ansari, Randal J Kaufman, Ming Liu, Peter Arvan. Proinsulin Misfolding is an Early Event in the Progression to Type 2 Diabetes (2019), eLife 2019;8:e44532. Selected for “eLife digest”
18. RS Jacob, A Anoop, and SK Maji. Protein Nanofibrils as Storage Forms of Peptide Drugs and Hormones (in Book: Biological and Bio-inspired Nanomaterials) (2019) Adv Exp Med Biol., 1174:265-290.
17. S Mehra, D Ghosh, R Kumar, M Mondal, LG Gadhe, S Das, A Anoop, NN Jha, RS Jacob, D Chatterjee, S Ray, N Singh, A Kumar, and SK Maji. Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils (2018), J Biol Chem, 293(34):12975-12991. Featured ‘Cover Art’ on JBC
16. Anoop Arunagiri, Leena Haataja, Corey N Cunningham, Neha Shrestha, Billy Tsai, Ling Qi, Ming Liu, Peter Arvan. Misfolded Proinsulin in the Endoplasmic Reticulum During Development of Beta Cell Failure in Diabetes (2018), Ann N Y Acad Sci, 1418(1):5-19
15. Ming Liu, Michael Weiss, Anoop Arunagiri, Jing Yong, Nischay Rege, Jinhong Sun, Leena Haataja, Randal J. Kaufman, Peter Arvan. Biosynthesis, structure, and folding of the insulin precursor protein (2018), Diabetes Obes Metab;20 Suppl 2:28-50
14. Corey Cunningham, Kaiyu He, Anoop Arunagiri, Adrienne W Paton, James C Paton, Peter Arvan, Billy Tsai. Chaperone-driven degradation of a misfolded proinsulin mutant in parallel with restoration of wild-type insulin secretion (2017), Diabetes, 66(3):741-753
13. RS Jacob, S Das, S Ghosh, A Anoop, NN Jha, T Khan, P Singru, A Kumar, and SK Maji. Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules (2016), Sci Rep, 6:23370
12. RS Jacob, E George, PK Singh, S Salot, A Anoop, NN Jha, S Sen and SK Maji. Cell adhesion on amyloid fibrils lacking integrin recognition motif (2016), J Biol Chem, 291(10):5278-98
11. NN Jha, D Ghosh, S Das, A Anoop, RS Jacob, PK Singh, N Ayyagari, INN Namboothiri, SK Maji. Effect of curcumin analogs on α-synuclein aggregation and cytotoxicity (2016), Sci Rep, 6:28511
10. S Sahay, D Ghosh, S Dwivedi, A Anoop, GM Mohite, M Kombrabail, G Krishnamoorthy, and SK Maji. Familial Parkinson's disease-associated mutations alter the site-specific microenvironment and dynamics of α-Synuclein (2015), J Biol Chem, 290(12):7804-22
9. S Ghosh, D Ghosh, S Ranganathan, A Anoop, S Palanirajan, NN Jha, R Padinhateeri, SK Maji. Investigating the intrinsic aggregation potential of evolutionarily conserved segments in p53 (2014), Biochemistry, 53(38): 5995–6010
8. A Anoop, S Ranganathan, BD Dhaked, NN Jha, S Pratihar, S Ghosh, S Sahay, S Kumar, S Das, M Kombrabail, K Agarwal, RS Jacob, P Singru, P Bhaumik, R Padinhateeri, A Kumar, and SK Maji. Elucidating the role of disulfide bond on amyloid formation and fibril reversibility of somatostatin-14: Relevance to its storage and secretion (2014), J Biol Chem, 289(24):16884-16903. Selected among “Papers of the Week”
7. D Ghosh, P Dutta, C Chakraborty, PK Singh, A Anoop, NN Jha, RS Jacob, M Mondal, S Mankar, S Das, S Malik, and SK Maji. Complexation of amyloid fibrils with charged conjugated polymers (2014), Langmuir, 30(13):3775-86
6. S Sahay, A Anoop, G Krishnamoorthy, and SK Maji. Site-specific Fluorescence Dynamics of α-Synuclein Fibrils using Time-Resolved Fluorescence Studies: Effect of Familial Parkinson’s Disease-Associated Mutations (2014), Biochemistry, 53(5):807-9
5. D Ghosh, M Mondal, GM Mohite, PK Singh, P Ranjan, A Anoop, S Ghosh, NN Jha, A Kumar, and SK Maji. The Parkinson’s Disease-Associated H50Q Mutation Accelerates α-Synuclein Aggregation in Vitro (2013), Biochemistry, 52 (40):6925–6927
4. NN Jha, A Anoop, S Ranganathan, GM Mohite, R Padinhateeri, and SK Maji. Characterization of amyloid formation by glucagon-like peptides: role of basic residues in heparin-mediated aggregation (2013), Biochemistry, 52 (49):8800–8810
3. S Mankar, A Anoop, S Sen, SK Maji. Nanomaterials: amyloids reflect their brighter side (2011), Nano Rev. 2011; 2: 10.3402/nano.v2i0.6032
2. RS Jacob, A Anoop, PK Singh and SK Maji Native functions of amyloid (in the book: Protein Aggregation) (2010), Nova Publishers, New York, pp. 79-109
1. A Anoop, PK Singh, RS Jacob, and SK Maji. CSF Biomarkers for Alzheimer's Disease Diagnosis (2010), Int J Alzheimers Dis. 2010; 2010: 606802. doi:10.4061/2010/606802