Our academic program is ideal for students working through structured curriculums. This includes high school and university syllabuses, postgraduate study, as well as professional certification exams. Our learners study a wide range of subjects and disciplines and cover the full spectrum of achievement from those wanting to more confidently secure a pass mark to global top rankers.

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.


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Dr Justin Sung is an ex junior doctor with teaching credentials that run a course called ICanStudy teaching study skills. He claims there are higher power learning techniques than spaced repetition and active recall (which he describes as lower tier only)

Research design and methods:  The study consisted of a 12-month randomized controlled trial of 147 health plan members with type 2 diabetes and obesity (BMI >or=27 kg/m(2)). Participants were randomized to lifestyle case management or usual care. Case management entailed individual and group education, support, and referral by registered dietitians; intervention cost was US dollars 350 per person. Individuals treated with usual care received educational material. Both groups received ongoing primary care. Outcomes were difference between groups for change in weight (kilograms), waist circumference (centimeters), HbA(1c), fasting lipid levels, use of prescription medications, and health-related quality of life.

Results:  Case management resulted in greater weight loss (P < 0.001), reduced waist circumference (P < 0.001), reduced HbA(1c) level (P = 0.02), less use of prescription medications (P = 0.03), and improved health-related quality of life (P < 0.001) compared with usual care. The 12-month group difference in weight loss and waist circumference was 3.0 kg (95% CI -5.4 to -0.6) and -4.2 cm (-6.8 to -1.6). HbA(1c) differences were greatest at 4 months (-0.59%, P = 0.006) but not significant by 12 months (-0.19%, P = 0.45). Participants in the case management group lowered their use of medications, primarily diabetes medications, by 0.8 medications per day more than participants treated with usual care (P = 0.03). In seven of nine quality-of-life domains, the case management group improved compared with usual care (P < 0.05).

Heavy cannabis use in adolescence and young adulthood is associated with various adverse physical and mental health effects [1]. These effects include cognitive impairment and an increased risk of depressive symptoms and suicidal ideation [1]. Heavy cannabis users are at risk for dependence [2, 3]. A longitudinal study of a cohort of (near) daily cannabis users found that almost 40% of the (near) daily cannabis users developed cannabis dependence (DSM-IV) [3].

Studies show that Internet-based programs for cannabis users are effective. Boumparis et al. recently published a systematic review with meta-analyses on digital prevention and treatment interventions to reduce cannabis use [14]. The meta-analyses showed a small but significant effect in favor of digital interventions compared to control conditions (waiting list, psycho-education or assessment only) [14]. These results are in line with results found in earlier meta-analyses on Internet and computer-based interventions for cannabis use [15,16,17].

The aim of this study is to test the effectiveness of the Internet-based intervention ICan compared to four online modules of educational information on cannabis in a sample of Dutch frequent cannabis users. We address the following research questions: (1) Is the ICan intervention more effective in reducing cannabis use than the control condition? (2) Is the ICan intervention more effective in improving positive attitudes towards seeking professional help for cannabis use-related problems than the control condition?

All spontaneously reported adverse events will be recorded. All serious adverse events will be reported to the accredited MREC (Medical Research Ethics Committee) that approved the protocol. Given the limited risks associated with a text-based self-help intervention, no Data Safety Monitoring Board or Safety Committee will be established for this study.

All outcome measures in this study are based on self-report questionnaires, not on biological measures such as hair or urine samples. It is not possible to determine whether participants will truthfully report their cannabis use or will give socially desirable answers. As mentioned before, the TLFB method is a psychometrically sound measure for the assessment of licit and illicit substance use [32]. Research has shown that the TLFB method for the detection of substance use, including cannabis use, has high levels of overall agreement with biological measures [32]. To control for potential socially desirable answers, the MCSDS will be included.

The ICan study is funded by the Dutch Ministry of Health, Welfare and Sport. The funder had no role in the design of the study and will not have a role during the data collection, data analysis, and writing of the manuscript.

All the authors are responsible for the design of the study. MO and MB wrote the first draft of the manuscript. AG and ML revised the manuscript critically. The authors read and approved the final manuscript.

The study is registered in the Netherlands Trial Register; identifier NL7668, registered on 17 April 2019, www.trialregister.nl/trial/7668. Ethical approval to carry out this study was obtained from an accredited medical research and ethics committee in the Netherlands (Medical Research Ethics Committees United, NL67449.100.18). All substantial amendments will be notified to the medical research and ethics committee. Informed consent is obtained from all participants included in the study.

You may qualify for our study if you or your child's healthcare provider has concerns regarding your toddler's development (communication, motor, behavior, or social concerns or developmental concerns). Toddlers must have older biological sibling(s) without autism.

ican! is a series of interactive, study-at-your-own-pace online training modules that includes information on the Older Americans Act (OAA), partnerships, operating a nutrition services program, menu planning, diversifying funding, and more.

Visit the ican! learning platform and follow the instructions to create an account or log into an existing account. If you are a returning user, use the module links below to start or resume training.

ACL funds the Nutrition and Aging Resource Center to build the capacity of senior nutrition programs funded by the Older Americans Act to provide high-quality, person-centered services and enhance program sustainability and resiliency.

The study considers their experiences as critical lessons for the design and implementation of initiatives to prevent violent extremism. In doing so, it makes an important contribution to an expanding evidence base on the reintegration of violent extremists.

The study models the potential impacts of a regional nuclear conflict and found that, given the increased size and power of their respective nuclear arsenals, the effects of a nuclear conflict between India and Pakistan would have even more catastrophic impacts than previously thought.

The purpose of the study is to examine the content validity index (CVI) and clinical utility (CU) of the iCan-Play assessment. iCan-Play is a play-based assessment for children with severe disabilities (SD), using assistive technology. We used mixed methods to analyze the CVI and CU data from seven experts. iCan-Play has good content validity and CU. The assessment provides a unique opportunity for children with SD to engage in active play through the use of assistive technology.

For the psychometric evaluation of the IcanSDM we conducted a secondary analysis of cross-sectional data. Cross-sectional data were taken from an implementation study to foster SDM uptake in a German healthcare setting [22]. In this implementation study, we used a stepped wedge design, a variant of a cluster randomized trial [40, 41]. Thereby, a multi-component SDM implementation program was implemented in three departments of a Comprehensive Cancer Center in Hamburg, Germany. Each department represented a cluster and all physicians and nurses within these clusters were included in the study. Each cluster was first observed under control conditions before it received the intervention in a randomized sequence. It was then observed under intervention condition until the end of the study [40, 41]. We performed an outcome evaluation at four measurement points as well as a process evaluation throughout all study phases [22]. The psychometric evaluation of the IcanSDM is a secondary analysis of baseline data (control condition) of this SDM implementation study. A waiver of consent for HCPs was obtained from the Ethics Committee, as proposed by current statements of ethical design of implementation research. Study participation was voluntary and HCPs were able to decline participation in the study by not filling out the survey.

Within the scope of a SDM implementation study [22], we conducted a secondary analysis of cross-sectional data. The IcanSDM was one of several measures [52,53,54] within one survey (27 items), which also assessed demographic characteristics (5 items).

We included all physicians and nurses working at one of the three departments of one Comprehensive Cancer Center in Germany, which participated in the SDM implementation study [22]. We expected physicians and nurses with diverse demographic characteristics including different sex, age and work experience taking part in this study. Physicians and nurses received the survey either (1) personally by a study team member, (2) via supervising nurses, or (3) via mail. After filling out the survey, participants had the options to either (1) personally hand the survey over to a study team member or (2) to send it back via mail. For quality control, we entered 20% of the data double and blinded into SPSS (IBM SPSS Statistics, Version 23). e24fc04721

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