Preprints posted during the Ebola and Zika outbreaks included novel analyses and new data, and most of those that were matched to peer-reviewed publications were available more than 100 days before publication. Despite the advantages, less than 5% of Ebola and Zika journal articles were posted as preprints prior to publication in journals. PLOS Medicine

When a scientist sends a grant application to the U.S. National Institutes of Health (NIH) in Bethesda, Maryland, and it goes through peer review, the entire process is supposed to be shrouded in secrecy. But late last year, NIH officials disclosed that they had discovered that someone involved in the proposal review process had violated confidentiality rules designed to protect its integrity. Science


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Hundreds of events, conversations and activities planned for the week in every state will encourage and support communities to take action on preventing disease and injury and improving health. American Public Health Association

This ASPR TRACIE fact sheet describes the major considerations healthcare facility emergency planners should take into account when developing patient surge management solutions for longer-duration events, such as weeks to months of managing seasonal illness surge. These considerations are different than those of planning to handle surge from a no-notice, short duration event. ASPR

Over the past three years, the Baylor College of Medicine team has developed and tested the Emergency Smart Pod, a rapidly deployable treatment center that can serve as an isolation unit for patient care during infectious disease outbreaks. Each pod can be shipped directly to its destination by boat, truck, or air, and assembled in less than five minutes with a team of four people. In addition, multiple pods can fit together like Legos to create larger medical clinics. DipNote

Population-based study through household interviews and serologic surveys. Data confirms intense CHIKV transmission during the continuing epidemic. Chronic pain developed in a high proportion of patients. Recommendations include training health professionals in management of chronic pain, which will improve the quality of life of chikungunya-affected persons. Emerging Infectious Diseases

Today, scientists are finding ever bigger viruses that pack impressive amounts of genetic material. The era of the giant virus began in 2003 with the discovery of the first Mimivirus. The viral titan is about 750 nanometers across with a genetic pantry boasting around 1.2 million base pairs of DNA, the information-toting bits often represented with A, T, C and G. Influenza A, for example, is roughly 100 nanometers across with only about 13,500 base pairs of genetic material. Science News

A newly identified coronavirus that killed nearly 25,000 piglets in 2016-17 in China emerged from horseshoe bats near the origin of the severe acute respiratory syndrome coronavirus (SARS-CoV), which emerged in 2002 in the same bat species. The new virus is named swine acute diarrhea syndrome coronavirus (SADS-CoV).

Four human cases of cholera have been identified on Vancouver Island. The cases have been linked to consumption of herring eggs that were harvested on the coast of the island. This string of cases has surprised health officials because cholera is rare in Canada; only seven cases of cholera throughout the country have occurred in the last five years, all of which were imported from cholera-endemic countries. The Disease Daily

From 13% to 34% of Ebola survivors will have post-infection vision impairment due to uveitis, an eye inflammation caused by cataracts. But because the Ebola virus is known to remain in ocular fluid even after clearing the rest of the body, doctors are hesitant to perform cataract or other ocular surgeries on survivors because of the risk of infection. CIDRAP

Scientists have identified potential biomarkers in nonhuman primates exposed to Ebola virus (EBOV) that appeared up to four days before the onset of fever. The work could pave the way for developing diagnostic tools to identify EBOV infection in humans even before symptoms appear. Science Daily

CDC will accept EIS disease detective applications starting April 16, 2018. EIS officers are selected from among highly qualified applicants drawn to public health service and interested in practicing applied epidemiology. CDC

HHS is seeking nominations for membership on the National Vaccine Advisory Committee. Apply by May 4, 2018. The Committee studies and recommends ways to encourage the availability of an adequate supply of safe and effective vaccination products in the United States; recommends research priorities and other measures to enhance the safety and efficacy of vaccines. Federal Register

The FDA Center for Biologics Evaluation and Research (CBER) is seeking a Director, Office of Blood Research and Review (OBRR). Apply by April 30, 2018. This position is located in Silver Spring, Maryland. FDA.gov

The film is a compelling drama of dedication, sacrifice, resilience and survival based on the true story of the people who risked their lives to prevent a catastrophic virus outbreak in Nigeria. Vanguard Nigeria 152ee80cbc

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