The fusion of two imaging modalities to form a new technique.
Hybrid imaging combines two or more imaging modalities to create a new and more powerful diagnostic tool. It allows for simultaneous visualization of anatomical structures which enhances diagnostic accuracy.
Improved diagnostic accuracy: Combines structural and functional information. Offers a more comprehensive and accurate diagnosis.
Enhanced and treatment planning: The fused images can guide surgical procedures and help in targeted interventions.
Reduced radiation exposure: Reduces need for multiple scans.
Personalized Medicine: Tailors treatments to patient needs.
Direct comparison of lesions with different imaging.
A step towards individualized medicine.
Hybrid Imaging will include a combination of two of the following imaging modalities.
Uses strong magnetic fields and radio waves to create a detailed image.
Uses X-rays and computer technology to create a detailed cross section image.
Uses small amounts of radioactive tracers to look for disease. Shows how organs and tissues are working.
Uses high frequency sound waves to create realtime images of the body's internal structures.
Uses x-ray imaging and injected contast (dye) to demonstrate how blood flows through the blood vessels.
Uses a radioactive tracer that travels to areas of high activity to create 3-D images and demonstrate organ functionality.
A hybrid imaging technique utilizing the functional uptake information of PET with the anatomical soft detail of MRI.
limited due to costs and expertise required
acquisition times are longer
lower ionizing radiation dose with higher detection rates than PET- CT
Benefits pediatric patients with chronic inflammatory conditions or maliganacy
Improved image alignment / coregistration due to simultaneous acquisition.
Co-registred display of live ultrasound with CT
The planes are displayed as an overlay or side by side with ultrasound
Enables direct comparison with reference images from the same view
Some applications include breast cancer treatments. Ultrasound fusion and CT scans can help identify lesions
It provides a more accurate and less operator dependent measurement of AAA.
Technique that combijesn images from MRI and ultrasound to create a 3D image
This fusion process helps urologits pinpoint suspicious areas for biopsy with greater accuarcy potentially leading to earlier detection
Fusion guided biopsies are more accuarte than traditional ultrasound guided biopsies
Biopsies are focues on specific areas of concern identified on MRI reducing number of biopsies needed.
The information gathered from fusion guided biopsies can help make a more effective treatment plan
Liver Applications -
Percutaneous Liver biopsies: Fusion imaging, such as combining ultrasound with CT or MRI, helps target small or poorly visualized liver lesions, reducing sampling errors and improving the accuracy of biopsies.
Radiofrequency Ablation (RFA)
It guides RFA in cases where the target lesion is not clearly visualized on conventional ultrasound , ensuring complete ablation and avoiding damage to surrounding tissues.
Breast cancer -
Fusion imaging th MRI or CT can improve the identification of small tumors, non mass enhancement and sentinel lymph nodes.
Musculoskeletal Imaging
Ultrasound guided fusion with CT, MRI, or PET can be helpful in diagnosing and targeting musculoskeletal lesions for biopsy or aspiration.
Fusion imaging bridges the gap between different imaging modalities, offering a more comprehensive and accurate view of the area of interest. This allows medical teams to perform more precise and safer interventional procedures. This leads to better patient outcomes and better patient care.
Sandulescu, D. L., Dumitrescu, D., Rogoveanu, I., & Saftoiu, A. (2011). Hybrid ultrasound imaging techniques (fusion imaging). World journal of gastroenterology, 17(1), 49–52. https://doi.org/10.3748/wjg.v17.i1.49
Shetty A, Hacking C, Sharma R, et al. Positron emission tomography. Reference article, Radiopaedia.org (Accessed on 15 Apr 2025)
https://doi.org/10.53347/rID-29716
Pfleger R, Yap J, Mellam Y, et al. Hybrid imaging. Reference article, Radiopaedia.org (Accessed on 15 Apr 2025) https://doi.org/10.53347/rID-29008
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