Our research interests are concentrated on novel functions of ion channels in various types of cells under physiological conditions and also at pathophysiological settings and the development of drugs acting on ion channels. Ion channels are essential molecular components for the regulation of not only the membrane excitability in nerves and muscles but also the cellular functions in non-excitable cells such as immune cells and osseous cells. Since abnormal activity or dysfunction of ion channels is often the cause of diseases and/or pathological conditions, they are potential targets of drug therapy, such as sodium channel blockers for cardiac arrhythmia, calcium channel blockers for hypertension, and potassium channel inhibitors for type II diabetics. Drubs acting on ion channels are expected to be extensively developed in near future because of new lines of genomic information about molecular basis and diversity of ion channels and also of information about structural biology of ion channels.
NEWS
July 1, 2025 Our research paper (Kir2.1 in macrophages) has been published in Am J Physiol Cell Physiol.
June 23, 2025 Our review paper has been published in Inflammation and Regeneration.
March 14, 2025 Our review paper has been published in J Pharmacol Sci.
Jan 5, 2025. Our review paper has been published in Inflammation and Regeneration.
Aug 19, 2024. Our reseach paper (Kv4.2 in pineal glands) has been published in Am J Physiol Cell Physiol.
Apr 16, 2024. Our paper has been published in Eur J Pharmacol.
Jan 29, 2024. Our paper has been published in Front Cardiovasc Med.
Nov 7, 2023. Our paper has been published in Am J Physiol Cell Physiol.
Mar 6, 2023. Dr. Gerald Zamponi (University of Calgary) visited our Lab and gave a lecture.
Feb 27, 2023. HP of our laboratory has been renewed.