Cancer Metastasis Lab
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Welcome to DD-Lab
At Datta Lab, we are striving to understand the molecular basis of cancer metastasis, particularly focusing on Triple-Negative Breast Cancer (TNBC) and colorectal cancer.
Research Focus
Genetic and Epigenetic Regulation in Cancer Metastasis
Investigate how genetic and epigenetic modifications influence tumor progression, invasion, and metastasis, with a specific focus on TNBC and colorectal cancer.
Unconventional Role of Chemokine Receptors in Cancer
Chemokine receptor biology in cancers is much more complex than currently comprehended. Intracellular reserves of chemokine receptors play pivotal role in cancer progression and metastasis. We explore all such unchartered territories here.
Targeted Therapies
Developing and evaluating small-molecule inhibitors such as PARP inhibitors and EZH2-EGFR dual inhibitors to disrupt specific pathways implicated in cancer progression and metastasis. Development of Indian TNBC patients-derived organoid (PDO) and Xenograft (PDX) models for drug testing, in order to explore novel avenues for therapeutic intervention in TNBC patients.
Our Approaches
Integrating cutting-edge techniques in cancer biology, genomics, and proteomics to uncover novel therapeutic targets.
Collaborating with multidisciplinary experts to foster innovation and accelerate discoveries in cancer metastasis research.
Translating fundamental research findings into potential clinical applications for better patient outcomes.
Join Us in the Fight against Cancer
We welcome collaborations, and talented individuals passionate about unravelling the complexities of cancer metastasis. Our lab provides an intellectually stimulating and collaborative environment for researchers committed to making a difference in cancer biology.
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