Dharma Lab
Chemical Biology & Drug Discovery
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Our goal is to transform chemical tools into next-generation therapeutics and to unravel unique mechanisms of action through innovation at the chemistry–biology interface.
Specifically, we synthesize and evaluate small molecules
to induce lipid droplet accumulation
as modulators of ferroptosis
covalent version for chemical probes and therapeutics identification
and to probe metal ion homeostasis. For more, reach out to the Research page.
What is new?
July 2025: Sai's work on lipid droplets accepted in Angewandte Chemie!
Congratulations to Sai, Santhosh, and Sathya!
July 2025: The lab welcomes new ly joined PhD students, Arun and Poornesh!
July 2025: The lab welcomes new ly joined PhD students, Arun and Poornesh!
July 2025: Congratulations, Dr. Sai Kumari Vechalapu, for successfully defending the PhD thesis!
July 2025: Congratulations, Dr. Sai Kumari Vechalapu, for successfully defending the PhD thesis!
July 2024: Congratulations to Dr. Sona Tiwari and Dr. Dharmendra Yadav for receiving their PhD degree in the convocation-2025! We proudly announce our lab's first set of PhD students' graduation!
July 2024: Congratulations to Dr. Sona Tiwari and Dr. Dharmendra Yadav for receiving their PhD degree in the convocation-2025! We proudly announce our lab's first set of PhD students' graduation!
Mar 2025: We announce that our US patent on new ferroptosis inducers has been published! Congratulations to all!
Mar 2025: We announce that our US patent on new ferroptosis inducers has been published! Congratulations to all!
Feb 2025: We announce that our Indian patent on new ferroptosis inducers has been granted! Congratulations to all!
Feb 2025: We announce that our Indian patent on new ferroptosis inducers has been granted! Congratulations to all!
Great start to this year!
Great start to this year!
Jan 2025: Sai's Lipid droplet work preprint is online now in BioRxiv. Congratulations, Sai, Santhosh and Sathya!
Jan 2025: Sai's Lipid droplet work preprint is online now in BioRxiv. Congratulations, Sai, Santhosh and Sathya!
Jan 2025: The lab welcomes Kamal Kishore. Kamal joined our lab as a PhD student.
Jan 2025: The lab welcomes Kamal Kishore. Kamal joined our lab as a PhD student.
Dec 2024: Congratulations, Dr. Sona Tiwari! We proudly announce our lab's first PhD student (by joining) defending her PhD thesis.
Dec 2024: Congratulations, Dr. Sona Tiwari! We proudly announce our lab's first PhD student (by joining) defending her PhD thesis.
Nov 2024: We announce that our Indian patent on new ferroptosis inducers has been granted! Congratulations to all!
Nov 2024: We announce that our Indian patent on new ferroptosis inducers has been granted! Congratulations to all!
Nov 2024: Sai has delivered her PhD open seminar to the department! Congratulations, Sai!
Nov 2024: Sai has delivered her PhD open seminar to the department! Congratulations, Sai!
Oct 2024: Sona's paper accepted for publication in Cell Reports Physical Science and is online now. Congratulations, everyone!
Oct 2024: Sona's paper accepted for publication in Cell Reports Physical Science and is online now. Congratulations, everyone!
Aug 2024: Sai's paper got accepted for publication in ACS Applied Bio Materials. Congratulations, everyone!
Aug 2024: Sai's paper got accepted for publication in ACS Applied Bio Materials. Congratulations, everyone!
Aug 2024: We have graduated our first PhD student from our lab. Congratulations, Dr. Dharmendra Kumar Yadav, for successfully defending the PhD thesis!
Aug 2024: We have graduated our first PhD student from our lab. Congratulations, Dr. Dharmendra Kumar Yadav, for successfully defending the PhD thesis!
Aug 2024: Sona has submitted her PhD thesis. Congratulations, Sona!.
Aug 2024: Sona has submitted her PhD thesis. Congratulations, Sona!.
Aug 2024: The Lab welcomes Pratiksha Kambhale, joined as a PhD student in our lab.
Aug 2024: The Lab welcomes Pratiksha Kambhale, joined as a PhD student in our lab.
June 2024: Sathyapriya Senthil secured the Best Poster Presentation award at the Fundamental and Advanced Research in Chemistry-2024 held at the Indian Institute of Technology, Guwahati, India. Congratulations, Sathya!
June 2024: Sathyapriya Senthil secured the Best Poster Presentation award at the Fundamental and Advanced Research in Chemistry-2024 held at the Indian Institute of Technology, Guwahati, India. Congratulations, Sathya!
May 2024: Dharma's editorial with Drs Eswar and Vish (University of Ohio, USA) is published in Front. Cell Dev. Biol.,!
May 2024: Dharma's editorial with Drs Eswar and Vish (University of Ohio, USA) is published in Front. Cell Dev. Biol.,!
Jan 2023: The Lab welcomes Isfa (PhD student), and Santhosh (project associate) joined our lab.
Jan 2023: The Lab welcomes Isfa (PhD student), and Santhosh (project associate) joined our lab.
May 2024: Sai's paper got accepted for publication in iScience. Congratulations everyone!
May 2024: Sai's paper got accepted for publication in iScience. Congratulations everyone!
May 2024: Dharmendra has submitted his PhD thesis. Congratulations, Dharmendra!
May 2024: Dharmendra has submitted his PhD thesis. Congratulations, Dharmendra!
April 2024: Sona has given her Open Seminar and moving towards submitting PhD thesis. Congratulations, Sona!
April 2024: Sona has given her Open Seminar and moving towards submitting PhD thesis. Congratulations, Sona!
Jan 2024: Dharmendra, Sona and Shathya's paper got accepted for publication in ChemComm. Congratulations everyone!
Jan 2024: Dharmendra, Sona and Shathya's paper got accepted for publication in ChemComm. Congratulations everyone!
Jan 2024: The Lab welcomes Uttej Sai Krishna, joined as a PhD student in our lab.
Jan 2024: The Lab welcomes Uttej Sai Krishna, joined as a PhD student in our lab.
Dec 2023: Viral Rawat secured first prize in a poster presentation at the International Conclave on AMR and Future Antibiotics (ICAFA 2023) held at the Department of Biological Sciences, SRM University, Andhra Pradesh. Congratulations, Viral!
Dec 2023: Viral Rawat secured first prize in a poster presentation at the International Conclave on AMR and Future Antibiotics (ICAFA 2023) held at the Department of Biological Sciences, SRM University, Andhra Pradesh. Congratulations, Viral!
Nov 2023: Indian patent application is filed for structurally new ferroptosis inducers. Congratulations to all the contributors (Dharmendra, Shweta, Sai, and Sona)!
Nov 2023: Indian patent application is filed for structurally new ferroptosis inducers. Congratulations to all the contributors (Dharmendra, Shweta, Sai, and Sona)!
Nov 2023: Sai Kumari received the ACS best poster presentation award in the category of Medicinal Chemistry and Chemical Biology at the RAIMM-2023 conducted at IIT Kanpur. Congratulations, Sai!
Nov 2023: Sai Kumari received the ACS best poster presentation award in the category of Medicinal Chemistry and Chemical Biology at the RAIMM-2023 conducted at IIT Kanpur. Congratulations, Sai!
Oct 2023: Dharmendra has given his Open Seminar and moving towards submitting PhD thesis. Congratulations Dharmendra!
Oct 2023: Dharmendra has given his Open Seminar and moving towards submitting PhD thesis. Congratulations Dharmendra!
Oct 2023: Shweta departs Dharma's lab, the lab will dearly miss you. Best wishes, Shweta!
Oct 2023: Shweta departs Dharma's lab, the lab will dearly miss you. Best wishes, Shweta!
July 2023: A colloborative research with Dr. Apparao group is published in ChemEurJ. Congratulations everyone!
July 2023: A colloborative research with Dr. Apparao group is published in ChemEurJ. Congratulations everyone!
June 2023: Krishna moved on to his next postdoctoral position at the University Health Network (UHN), University of Toronto, Canada. Congratulations Krishna!
June 2023: Krishna moved on to his next postdoctoral position at the University Health Network (UHN), University of Toronto, Canada. Congratulations Krishna!
Jan 2023: The Lab welcomes Isfa (PhD student), and Santhosh (project associate) joined our lab.
Jan 2023: The Lab welcomes Isfa (PhD student), and Santhosh (project associate) joined our lab.
Oct 2022: Sridhar is taking up his next postdoctoral position in the lab of Prof Richard Hartley, at the University of Glasgow, UK. Congratulations Sridhar!
Oct 2022: Sridhar is taking up his next postdoctoral position in the lab of Prof Richard Hartley, at the University of Glasgow, UK. Congratulations Sridhar!
Oct 2022: Dr. V. Krishna Rao has joined our lab as Project Associate. Welcome Krishna!
Oct 2022: Dr. V. Krishna Rao has joined our lab as Project Associate. Welcome Krishna!
Sep 2022: Viral, Sona and Shweta's paper and our lab's first paper-got accepted for publication in ChemComm. Congratulations everyone!
Sep 2022: Viral, Sona and Shweta's paper and our lab's first paper-got accepted for publication in ChemComm. Congratulations everyone!
Aug 2022: Dharma lab received a grant support from Indian Council of Medical Research (ICMR) for antibacterial agent development!
Aug 2022: Dharma lab received a grant support from Indian Council of Medical Research (ICMR) for antibacterial agent development!
July 2022: Sona is recognized for best poster presentation by the ACS-Journal of Medicinal Chemistry in 29th Chemical Research Society of India (CRSI) National Symposium in Chemistry held at IISER-Mohali.
July 2022: Sona is recognized for best poster presentation by the ACS-Journal of Medicinal Chemistry in 29th Chemical Research Society of India (CRSI) National Symposium in Chemistry held at IISER-Mohali.
Nov 2021: Dharma lab received a grant support from DST-Science and Engineering Research Board (SERB)
Nov 2021: Dharma lab received a grant support from DST-Science and Engineering Research Board (SERB)
Mar 2020: CRSI-Young Scientist Award-2019 is conferred on Dharma by Chemical Research Society of India (CRSI)
Mar 2020: CRSI-Young Scientist Award-2019 is conferred on Dharma by Chemical Research Society of India (CRSI)
May 2020: Dharma is awarded the Har-Gobind Khorana Young Innovative Biotechnologist Award (IYBA) Grant
May 2020: Dharma is awarded the Har-Gobind Khorana Young Innovative Biotechnologist Award (IYBA) Grant
Feb 2020: Dharma lab received grant support from Council of Scientific and Industrial Research (CSIR)-India
Feb 2020: Dharma lab received grant support from Council of Scientific and Industrial Research (CSIR)-India
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