2024
2023
J Seira Curto, MR Fernandez, J Cladera, N Benseny-Cases, ... International journal of molecular sciences 24 (9), 8408
R Delli Ponti, L Broglia, A Vandelli, A Armaos, MT Burgas, ... IUBMB Life 75 (5), 411-426
A Vandelli, M Arnal Segura, M Monti, J Fiorentino, L Broglia, A Colantoni, ... Bioinformatics 39 (1), btac847
2022
J Seira Curto, A Surroca Lopez, M Casals Sanchez, I Tic, ... Frontiers in Molecular Biosciences 9, 926702 (*Corresponding author)
A Vandelli, FC Samper, MT Burgas, de Groot, NS*, GG Tartaglia Journal of Molecular Biology 434 (1), 167159 (*Corresponding author)
2021
Armaos, A; Zacco, E; de Groot, NS*; Tartaglia, GG. RNA-protein interactions: Central players in coordination of regulatory networks BioEssays 43(2):e2000118. 2020 (*Corresponding author)
2020
de Groot, NS*; Torrent Burgas M., Bacteria use structural imperfect mimicry to hijack the host interactome. PLoS Computational Biology. 1008395. 2020 (*Corresponding author)
Lorenzo Gotor N., Armaos A., Calloni G., Torrent Burgas, M., Vabulas, RM, de Groot, NS*,Tartaglia G.G. RNA-binding and prion domains: the Yin and Yang of phase separation. Nucleic Acids Research, 48, 9491-9504. 2020 (*Corresponding author)
2019
de Groot, NS*; Torrent Burgas, M. A coordinated response at the transcriptome and interactome level is required to ensure uropathogenic escherichia coli survival during bacteremia. Microorganisms. 7(9). pii: E292. 2019 (*Corresponding author)
de Groot, NS; Armaos, A; Graña-Montes, R; Alriquet, M; Calloni, G; Vabulas, RM; Tartaglia, GG. RNA structure drives protein interaction and modulates phase separation. Nature Communications. 10(1):3246. 2019
de Groot, NS*; Torrent Burgas, M; Ravarani, CN; Trusina, A; Ventura, S; Babu, MM. The fitness cost and benefit of phase-separated protein deposits. Molecular Systems Biology. 15(4):e8075. 2019. (*Corresponding author)
Zacco, E; Graña-Montes, R; Martin, SR; de Groot, NS; Alfano, C; Tartaglia, GG; Pastore, A. RNA as a key factor in driving or preventing self-assembly of the TAR DNA-binding protein 43. Journal of Molecular Biology. 431(8):1671-1688. 2019
2018
Torrent, M; Chalancon, G; de Groot, NS; Babu, MM. Cells alter their tRNA abundance to selectively regulate protein synthesis during stress conditions. Science Signaling. 1, 546. 2018.
Pallares, I; de Groot, NS; Iglesias, V; Santana, R; Ventura, S. Discovering Putative Prion-Like Proteins in Plasmodium falciparum: A Computational and Experimental Analysis. In Frontiers in Microbiology. 9:1737. 2017.
2017
Batlle, C; de Groot, NS; Iglesias, V; Ventura, S. Characterization of Soft Amyloid Cores in Human Prion-Like Proteins. Scientific Reports. 7,12134. 2017.
Chavali, S; Chavali, P; Chalancon, G; de Groot, NS; Gemayel, R; Latysheva, N; Ing-Simmons, E; Verstrepen, KJ; Balaji, S; Babu, MM. Constraints and consequences of the emergence of amino acid repeats in eukaryotic proteins. Nature Structural and Molecular Biology. 9, 765-777. 2017.
Carijaa, A; Navarro, S; de Groot, NS; Ventura, S. Protein aggregation into insoluble deposits protects from oxidative stress. Redox Biology. 12, 699-711. 2017.
Crua, N; Muñoz, E; de Groot, NS*; Torrent, M. Centrality in the host-pathogen interactome is associated with pathogen fitness during infection. Nature Communications. 8, pp. 14092. 2017. (*Corresponding author)
2016
Marchese, D*; de Groot, NS*; Lorenzo Gotor, N; Livi, CM; Tartaglia, GG. Advances in the characterization of RNA-binding proteins. Wiley Interdiscip Rev RNA. 7 - 6, pp. 793 – 810. 2016. (*Both contributed equally)
Sant'Anna, R; Fernández, MR; Batlle, C; Navarro, S; de Groot, NS; Serpell, L; Ventura, S. Characterization of amyloid cores in prion domains. Scientific Reports. 6, pp. 34274. 2016.
Lopez, L; Carrodeaguas, J; de Groot, NS; Ventura, S; Sancho, J. Benzbromarone, quercetin and folic acid inhibit amylin aggregation. International Journal of Molecular Sciences. 17 - 6, pp. E964. 2016.
Ravarani, C; Chalancon, G; de Groot, NS; Babu MM. Interplay between TBP and its binding site reveals the mechanistic basis of gene expression stochasticity. Nature Communications. 7, pp. 10417. 2016.
2015
de Groot, NS*; Torrent M. Is membrane homeostasis the missing link between inflammation and neurodegenerative diseases?. Cellular and Molecular Life Sciences. 72 - 24, pp. 4795 - 4805. 2015. (*Corresponding author)
Iglesias, V; de Groot, NS*; Ventura, S. Computational analysis of candidate prion-like proteins in bacteria and their role. Frontiers in Microbiology. 6 - 1123, 2015. (*Corresponding author)
de Groot, NS*; Gomes, RA; Villar-Piqué, A; Babu MM; Varela Coelho, A; Ventura, S. Proteome response at the edge of protein aggregation. Open Biology. 2015; 5(2):140221 (*Corresponding author)
Fernandez-Busquets, X; de Groot, NS; Ventura, S. Recent structural and computational insights into conformational diseases: A review. Frontiers in Medicinal Chemistry 7, Bentham Science Publishers Ltd. 2015; 134-82 (49)
2014
van de Lee, R; Lang, B; Kruse, K; Gsponer, J; Sanchez de Groot, N; Huynen, M; Matouschek, A; Fuxreiter, M; Babu, MM. Intrinsically disordered segments affect protein half-life in the cell and during evolution. Cell Reports. 2014; 8(6):1832-44
2013
Babu, MM; van der Lee, R; de Groot, NS; Gsponer, J; Intrinsically Disordered Proteins: Regulation and Disease. Biomolecular Forms and Functions: A Celebration of 50 Years of the Ramachandran Map, 2013; 346-361
2012
Sanchez de Groot, N; Lang, B; Ventura, S; Gsponer, J; Babu, MM; Evolutionary selection for protein aggregation. Biochem Soc Trans. 2012; 40(5):1032-7 (*Corresponding author)
Villar-Pique, A; de Groot, NS; Sabaté, R; Acebrón, SP; Celaya, G; Fernàndez-Busquets, X; Muga, A; Ventura, S; The effect of amyloidogenic peptides on bacterial aging correlates with their intrinsic aggregation propensity. J Mol Biol. 2012 421(2-3):270-81
Villar-Piqué, A; Espargaró, A; Sabaté, R; de Groot, NS; Ventura, S; Using bacterial inclusion bodies to screen for amyloid aggregation inhibitors. Microb Cell Fact. 2012; 11:55
Graña-Montes, R*; de Groot, NS*; Castillo, V; Sancho, J; Velazquez-Campoy, A; Ventura, S; Contribution of disulfide bonds to stability, folding and aggregation kinetics: The PI3-SH3 domain case. Antioxid. Redox Signal. 2012; 16(1):1-15 (*Both authors contributed equally)
de Groot, NS; Castillo, V; Graña-Montes, R; Ventura, S; AGGRESCAN: Method, Application and Perspectives for Drug Design. Meth. Mol. Bio. Humana Press. Springer. New York, 2012; 819:199-220
2011
García-Fruitós, E; Sabaté, R; de Groot, NS; Villaverde, A; Ventura, S; Biological role of bacterial inclusion bodies: a model for amyloid aggregation. FEBS J. 2011; 278(14):2419-2
Babu, MM; van der Lee, R; de Groot, NS; Gsponer, J; Intrinsically Disordered Proteins: Regulation and Disease. Curr. Opin. Struct. Biol., 2011; 21(3):432-40
Morell, M; de Groot, NS; Vendrell, J; Avilés, FX; Ventura S; Linking amyloid protein aggregation and yeast survival. Mol. Biosys.t. 2011; 7(4):1121-8
2010
Sabate, R; Espargaro, A; de Groot, NS; Valle-Delgado, JJ; Fernandez-Busquets, X; Ventura, S; The Role of Protein Sequence and Amino Acid Composition in Amyloid Formation: Scrambling and Backward Reading of IAPP Amyloid Fibrils. J. Mol. Biol., 2010; Nov 26;404(2):337-52
Valle-Delgado, JJ; Alfonso-Prieto, M; de Groot, NS; Ventura, S; Samitier, J; Rovira, C; Fernàndez-Busquets; Modulation of Aβ42 fibrillogenesis by glycosaminoglycan structure. FASEB J., 2010; 24(11): 4250-4261
Sabater, R*; de Groot, NS*; Ventura, S Protein Folding and Aggregation in Bacteria. Cell Mol. Life Sci., 2010; 67(16):2695-2715 (*Both contributed equally)
de Groot, NS; Ventura, S; Protein aggregation profile of the bacterial cytosol. PLoS One, 2010; 5: e9383.
2009
de Groot, NS; Sabate, R; Ventura, S; Amyloids in bacterial inclusion bodies. Trends Biochem. Sci., 2009; 34(8):408-416
Rodríguez-Rodríguez, C; Sanchez de Groot, N; Rimola, A; Alvarez-Larena, A; Lloveras, V; Vidal-Gancedo, J; Ventura, S; Vendrell, J; Sodupe, M; González-Duarte P; Design, Selection, and Characterization of Thioflavin-Based Intercalation Compounds with Metal Chelating Properties for Application in Alzheimer's Disease. J. Am. Chem. Soc., 2009; 131(4):1436-1451
2008
Espargaró, A; Castillo, V; de Groot, NS; Ventura, S; The in vivo and in vitro aggregation properties of globular proteins correlate with their conformational stability: The SH3 case. J. Mol. Biol., 2008; 378(5):1116-1131
de Groot, NS; Espargaro, A; Morell, M; Ventura, S; Studies on bacterial inclusion bodies. Future Microbiol., 2008; 3(4):423-435
Fernàndez-Busquets,X; de Groot, NS; Fernandez, D; Ventura, S; Recent structural and computational insights into conformational diseases. Curr. Med. Chem., 2008, 15:1336-1349
2007
Sabaté, R; Baxa, U; Benkemoun, L; Sanchez de Groot, N; Coulary-Salin, B; Maddelein, ML; Malato, L; Ventura, S; Steven, AC; Saupe, SJ; Prion and non-prion amyloids of the HET-s prion forming domain. J. Mol. Biol., 2007; 370(4):768-783
Morell, M*; de Groot, NS*; Ventura, S.; From dust balls to biocatalysts. A new view of bacterial inclusion bodies. Europe BIOforum, 2007; 11:42-43 (*Both contributed equally)
Conchillo-Sole*, O; de Groot*, NS; Aviles, FX; Daura, X; Vendrell, J; Ventura, S; AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides. BMC Bioinformatics, 2007; 8:65 (*Both contributed equally)
de Groot, NS; Parella, T; Vendrell, J; Ventura, S; Ile-Phe dipeptide self-assembly: Clues to amyloid formation. Biophy. J., 2007; 92(5): 1732-1741
2006
de Groot, NS; Ventura, S; Protein activity in bacterial inclusion bodies correlates with predicted aggregation rates. J. Biotech., 2006; 125 (1): 110-113
de Groot, NS; Ventura, S Effect of temperature on protein quality in bacterial inclusion bodies. FEBS Lett., 2006; 580(27): 6471-76
de Groot, NS; Aviles, FX; Vendrell, J; Ventura, S; Mutagenesis of the central hydrophobic cluster in Abeta 42 Alzheimer's peptide. FEBS J., 2006; 273 (3): 658-668
2005
de Groot, NS; Pallares, I; Aviles, FX; Vendrell, J; Ventura, S; Prediction of "hot spots" of aggregation in disease-linked polypeptides. BMC Struct Biol, 2005; 5:18
de Groot, NS; Ventura, S; Amyloid fibril formation by bovine cytochrome C. Spectroscopy, 2005; 19 (4): 199-205