Dedalo Marchetti studied Physics and Astrophysics at “La Sapienza”, University of Rome and got a PhD in physics at RomaTre University.
From 2016, he started to investigate the preparation phase of medium-large earthquakes in the world with INGV (Italian National Institute of Geophysics and Vulcanology) and made 2 postdoctoral fellowships in China (2018-2023) with NUIST and Jilin University.

Several researchers proposed some mechanisms for the so-called Lithosphere-Atmosphere-Ionosphere Coupling (LAIC) phenomena, in particular, Friedmann Freund suggested that the variation of the stress on the fault that is expected in the later stages of preparation of an earthquake by Scholtz) can release some positive-hole particles. The positive-holes can migrates on the surface by fluids movements or as a electrical charges migration. On the surface the release of charged particles (and radon) can ionise the air producing aerosol particle, warming of the surface temperature and so on. This variations are able to reach the ionosphere, the layer that goes about from 50 to 1000 km altitude above the ground. This chain has been proposed and empirically verified in several cases by Pulinets and Ouzounov.

The main focus of the research is to find evidence and possibly a physical mechanism for the Lithosphere - Atmosphere - Ionosphere Coupling (LAIC) effect. Several pieces of evidence have been found, for example, but not only investigating the Italian seismic sequence that unfortunately hit Italy (AMtraice-Norcia) in 2016-2017, on Indonesia 2018-09-28 Mw = 7.5, Ridgecrest(California) 2019-07-06 Mw=7.1 earthquakes and many more other case studies published in several publications in international peer-reviewed journals.

A very big work carried out with the support of the SAFE project (coordinated by prof. Angelo De Santis and funded by ESA) was to correlate the ionospheric magnetic and electron density anomalies detected by Swarm three-satellites constellation with the shallow M5.5+ earthquakes that occurred from the launch of this Science Earth observation mission of European Space Agency. We not only found high concentrations of anomalies that preceded the earthquake occurrence from a few days to several months, but we also confirmed that larger earthquakes are anticipated by precursors with longer time, as empirically proposed by Japanese seismologist Rikitake.