Research Career

TECHNICAL EXPERTISE

• Biochemistry: Mammalian tissue Culture, protein expression/purification, protein characterization techniques (SDS PAGE, qualitative and quantitative Western Blotting), Cell Staining, lipid extraction from cells, TLC and HPTLC, Metabolic labeling.

• Biophysical Chemistry: Protein–protein interactions, lipid–protein interactions, lipid-Cyclodextrin interactions, drug-protein and drug-lipid interactions, working with model biomimicking membranes such as vesicles, micelles and reverse micelles.

• Instrumentation: UV - Visible absorption, Steady state and time resolved fluorescence, Steady state and time resolved anisotropy, Kinetics, Circular Dichroism, Dynamic Light Scattering, Fluorescence Microscopic Imaging.

• Computational Chemistry: Operational knowledge of computational Chemistry and theoretical chemistry through Gaussian 98, 03 & 09 programs, Molecular Dynamics Simulation using Gromacs and Molecular Docking through AUTODOCK.

Ongoing Works:

1. Novel bio-imperative Schiff's bases' synthesis and pharmacological invitro binding studies with biomimicking environments through spectroscopic intervention and theoretical correlation.

2. Development of fluorescent active molecular logic-gate sensors and their application studies.

3. Theoretical molecular dynamics simulation to study probe - biomimicking environment interactions in ground and excited states.

4. Computational modelling of photoprocesses occurring in functionalized compounds for advanced sensing and catalytic applications.

5. Design and synthesis of functionalized nanoformulations for bioimperative applications.

6. Theoretical hypotheses to drive the mechanistic roadmap of engineered nanoformulations in theranostics.