Research
Our laboratory develops radiation detection, dosimetry, imaging, and computational technologies to address fundamental and translational challenges in modern radiation medicine.
Our research is organized around five interconnected areas.
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1 | Advanced Scintillation Detectors
We develop miniaturized scintillation detectors and optical readout systems for high-resolution radiation measurements.
Our research includes:
• Inorganic and organic scintillator materials
• Fiber-integrated scintillation micro-probes
• Detector geometry optimization
• Optical photon transport
• Detector sensitivity and dynamic range
• Scintillation and Cherenkov signal separation
• Detector arrays and multiplexed readout
• Novel fabrication and encapsulation approaches
Goal: Develop compact radiation detectors capable of high-sensitivity, high-resolution, and real-time measurements across a broad range of radiation environments.
2 | Precision & Small-Field Dosimetry
Modern radiation therapy increasingly uses highly conformal radiation fields with steep dose gradients. Accurate measurement under these conditions remains challenging because detector size, material composition, and volume averaging can perturb or distort the measured dose distribution.
We investigate:
• Small-field output factors
• Beam-profile measurements
• Detector volume averaging
• Detector-induced dose perturbation
• SRS/SBRT dosimetry
• High-gradient dose measurements
• Real-time in vivo dosimetry
• Patient-specific treatment verification
Experimental measurements are combined with Monte Carlo simulations and reference dosimeters to characterize detector response and establish reliable measurement methodologies.
3 | FLASH & Emerging Radiation Therapy
Ultra-high-dose-rate FLASH radiation therapy introduces detector challenges that are fundamentally different from conventional radiation therapy.
Our laboratory investigates detector response under:
• Electron FLASH
• Proton FLASH
• Very-high-energy electron (VHEE) beams
• High dose-per-pulse conditions
• Ultra-high instantaneous dose rates
Research focuses on detector linearity, saturation, temporal response, dose-per-pulse dependence, radiation-induced optical signals, and real-time beam monitoring.
Long-term objective: Enable reliable real-time dosimetry and beam monitoring for emerging ultra-high-dose-rate radiation therapies.
4 | Monte Carlo & Multiphysics Modeling
Computational modeling provides a fundamental framework for understanding radiation-detector interactions that cannot always be isolated experimentally.
We use:
GATE | Geant4 | TOPAS
to investigate:
• Radiation transport
• Energy deposition
• Detector perturbation
• Detector geometry effects
• Small-field dosimetry
• Optical photon generation and transport
• Scattering and light collection
• Detector response optimization
Our computational studies are closely integrated with experimental measurements to provide rigorous validation of detector performance.
5 | Molecular Radiation Imaging
We are developing advanced detector and computational concepts for high-resolution molecular and nuclear medicine imaging.
Research interests include:
• Scintillator detector arrays
• Gamma-ray detection
• SPECT imaging
• Quantitative radionuclide imaging
• Small-lesion visualization
• Partial-volume effects
• Activity quantification
• AI-assisted image enhancement and reconstruction
• Patient-specific radiopharmaceutical dosimetry
Our goal is to combine advances in detector physics and computational imaging to improve spatial resolution, sensitivity, and quantitative accuracy in molecular imaging
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