Instrumental-variable (IV) estimation is an essential method for applied researchers across the social and behavioral sciences who analyze randomized control trials marred by noncompliance or leverage partially exogenous treatment variation in observational studies. The potential outcome framework is a popular model to motivate the assumptions underlying the identification of the local average treatment effect (LATE) and to stratify the sample into compliers, always-takers, and never-takers. However, applied research has thus far paid little attention to the characteristics of compliers and noncompliers. Yet, profiling compliers and noncompliers is necessary to understand what subpopulation the researcher is making inferences about and an important first step in evaluating the external validity (or lack thereof) of the LATE estimated for compliers. In this letter, we discuss the assumptions necessary for profiling, which are weaker than the assumptions necessary for identifying the LATE if the instrument is randomly assigned. We introduce a simple and general method to characterize compliers, always-takers, and never-takers in terms of their covariates and provide easy-to-use software in R and STATA that implements our estimator. We hope that our method and software facilitate the profiling of compliers and noncompliers as a standard practice accompanying any IV analysis.

Leonard was born in Kingston in 1920; his grandfather, Peter Van Dyke, had bought several houses on Gage Street in the 1800s. Leonard married Vera, who had moved to Kingston from Virginia as a teenager, during World War II and served overseas. After the war the couple moved to the Rondout, where they brought up their 11 children.


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"Telstar" is a 1962 instrumental by the English band the Tornados, written and produced by Joe Meek. It reached number one on the UK Singles Chart and the US Billboard Hot 100 in December 1962 (the second British recording to reach number one on that chart in the year, after "Stranger on the Shore" in May). It was the second instrumental single to hit number one in 1962 on both the US and UK weekly charts.[note 1]

While at the Frost School of Music she served as a teaching assistant in instrumental conducting, instructor of undergraduate conductor techniques and commencement band conductor. She majored in instrumental conducting at the Frost School.

Paul Chinen, D.M.A. 2019, has been appointed Principal Oboe of the Great Falls Symphony and Oboist of the Chinook Winds Woodwind Quintet. Since relocating to Great Falls, he has toured across Montana giving outreach and formal concerts with the Chinook Winds and has performed with several special guest artists with the Great Falls Symphony, including Bela Fleck.

Gagnon has won numerous music competitions in Canada and the United States, and as a member of the Ibis Camerata, he performed in Russia, at the White Nights Festival, in Serbia and Switzerland. In 2006, their first recording, Glisten, was released by Albany Records. She majored in instrumental performance at the Frost School of Music.

Hanish has taught on the faculties of the Beck Center for the Arts and the Avon School of Music. She has been a chamber music coach for the CIM Summer Chamber Music Camp, as well as the Michigan ASTA Jr. High String Camp. Hanish majored in instrumental performance at the Frost School of Music.

Wells published The Art of Scales in 2009, a guide to a new approach to learning scales. He is well-known online for his YouTube video, The Impossible Duet: Handel-Halvorsen Passacaglia for Cello and Violin, which has more than 1.6 million views. He majored in instrumental performance at the Frost School of Music.

Dr. Volkow's work has been instrumental in demonstrating that drug addiction is a brain disorder. As a research psychiatrist, Dr. Volkow pioneered the use of brain imaging to investigate how substance use affects brain functions. In particular, her studies have documented how changes in the dopamine system affect the functions of brain regions involved with reward and self-control in addiction. She has also made important contributions to the neurobiology of obesity, ADHD, and aging.

Sensory analysis is a scientific discipline with specific purposes, which measures and explores the stimuli perceived by the senses against different variants and whose results can be validated through instrumental methods. In the present study, the target was established utilizing convocation, selection, and training of a group of semi-trained judges to serve as a basis for the correlation of sensory analysis with instrumental analysis at the Agrarian University, Ecuador. The study was carried out in 2023 at the Agrarian University of Ecuador. A general call was made, where finalists were trained twice a week for one month as sensory judges in terms of hedonic scale and texture (adhesiveness, homogeneity, and viscosity) to determine different texture parameters, using as a preliminary test of capabilities, the evaluation of 3 different formulations of a dressing based on passion fruit juice and babaco. Once the treatment with the highest sensory acceptability was determined, an instrumental, microbiological, and physical-chemical analysis was conducted. The results were tabulated through an analysis of variance (ANOVA) using the Tukey 5% method with the RStudio statically data program. The research results from the call, 150 participants entered, of which 30 final panelists were determined who, through training, fulled the established requirements and, in turn, chose the second formulation of the dressing as the best treatment, which employs back extrusion test as an instrumental validation parameter, provided an overview of the relationship between sensory and instrumental analysis and its correlation. The correlation of the analyses to the texture profile evidenced the variability presented by the different treatments. Based on this, the present study emphasizes the importance of developing a comparison between sensory training with semi-trained judges and instrumental analyses, presenting a significant impact on the evaluation within the product development process. Assessing the strategic correlation of both approaches can provide a more comprehensive and balanced assessment of sensory quality, leveraging the strength of human subjectivity and the precision of instrumental measurements.

Several research projects have attempted to elucidate the effects and changes produced by components and ingredients within food systems directly related to the texture.12 Focused on this, the back extrusion test (reverse extrusion) provides different applications such as texturization malleability of samples for purposes determined in the textural properties of a viscoelastic fluid,13,14 being an empirical test that allows correlation with sensory analysis considering these test provide a repeatable, reproducible, and highly sensitive measurements of stickiness, toughness and hardness results.15 Based on the above, the comprehensive evaluation of food texture involves a multidisciplinary analysis where the combination, correlation of techniques, and statistical support represent the best alternatives as they provide convenient and valuable approaches.16

Based on the importance of sensory criteria as quality parameter measurers, the objective of this research was to convene, filter, train, and select a group of semi-trained judges to serve as a basis for the correlation of sensory analysis with instrumental analysis, an action required to determine the relationship index between both studies, where the instrumental analysis validates the results obtained from the semi-trained judges, for which a dressing was developed, the same that used passion fruit (Passiflora edulis) and babaco (Carica pentagona) as exotic fruits, also evaluating the physical-chemical requirements (pH and fat), microbiological (mesophilic aerobes, Staphylococcus aureus, total coliforms, molds, and yeasts), as a prevention protocol for the panelists, and instrumental (the Back extrusion test), as well as training a panel of tasters that will allow the development of new research in this field of study.

In order to apply the correlation between sensory and instrumental analysis, several activities were designed and applied to a group of students from the Agrarian University of Ecuador from the Agroindustry career, with a previous concern to the participants, which consisted of recruitment, selection, training, and testing of skills related to sensory analysis specifically for the texture criterion, stages supported according to the methodology set out by ISO 8586-:2012,21 and ISO 6658:2012,22 and helpful previous researches.23,24 Upon completion of the process, a group of 30 panelists was selected and trained on different sensory stimuli topics referring to food texture. Once the panelists were trained, the texture prole was determined as a preliminary test with three samples of different formulations of passion fruit (Passiflora edulis) and babaco (Carica pentagona) dressing and a control product, the other hand; these samples were subjected to a compression-extrusion analysis with five repetitions in order to correlate the variables of the sensory analysis with the instrumental analysis and their relationship in the study to a passion fruit (Passiflora edulis) and babaco (Carica pentagona) dressing, in addition to mandatory specifications such as microbiological analysis according to the Colombian Technical Standard NTC 4305.25

The design applied for the development of a sensory screening; a call was made to university students between 18 and 23 years old with previous knowledge in sensory analysis, to whom a survey was made, previously validated by five professionals in sensory analysis and food engineering and oriented to know several parameters for the profile of sensory panelists to filter the suitable candidates for the pertinent purposes. Among the criteria consulted for selection were interest and motivation, attitude towards food, health, and determination in the non-consumption of alcohol, tobacco, or controlled substances (non-smokers, non-drinkers), absence to digestive or respiratory tract diseases, and oropharyngeal lesions. Once the call for applications was completed, the participation of individuals who did not meet the parameters of alcohol or controlled substances non-consumption and absences of diseases or injuries described above was discarded. 17dc91bb1f

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