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Yasuharu Tokuda, MD, MPH, PhD

Director and Project Leader, Muribushi Center for Teaching Hospitals, Okinawa
General Medicine Education and Research Institute (Established in 2014): We Educate Young Medical Doctors in Japan, Conduct Public Health Research, Deliver Lectures at Hospitals and Academic Institutions Around the World.

Current Academic Appointments

Tsukuba University (Adjunct Professor)
Ryukyu University (Adjunct Professor)
St. Marianna University (Adjunct Professor)
Dokkyo Medical University (Adjunct Professor)
Tokyo Science University (Adjunct Professor)
Keio University (Adjunct Faculty)
Health and Global Policy Institute (Fellow)
Taiwan Association of Hospital Medicine (International Consultant)

English Language Publications

1. Tokuda Y. Teaching ethics in Japan. Lancet. 1995;345(8964):1574.

2. Tokuda Y. Unscientific speculation. Nature. 1996;383(6599):381.

3. Tokuda Y, Kuwabara K, Miyagi Y. Tetanus in Okinawa Chubu Hospital. Journal of Okinawa Chubu Hospital. 1997;23:30-33.

4. Kato J, Toyozato N, Hattori T, Motomura K, Tokuda Y. Long-term enteral nutrition-associated copper deficiency anemia and leukopenia: A case report and review of the literature. Journal of Okinawa Chubu Hospital. 1998;24(2):20-23.

5. Narita M, Sudo S, Tokuda Y. Syndrome of Passive Hepatic Congestion Mimicking Acute Abdomen in a Patient with Hyperthyroidism: A Case Report and Review of the Literature. Journal of Okinawa Chubu Hospital. 1998;24(2):24-26.

6. Tokuda Y. Low-dose spiral computed tomography for lung-cancer screening. Lancet. 1998;352(9123):235-236; author reply 236-237.

7. Tokuda Y. Physicians and biological warfare agents. JAMA. 1998;279(4):273-274.

8. Chang D, Koketsu H, Fukunaga T, Miyagi T, Kitamura T, Tamaki K, Arashiro K, Miyagi Y, Tokuda Y. Pyoderma Gangrenosum Associated with Myelodysplastic Syndrome. Journal of Okinawa Chubu Hospital. 1999;25(1):16-20.

9. Tokuda Y, Kato J. Aspirin and risk of hemorrhagic stroke. JAMA. 1999;282(8):732; author reply 732-733.

10. Higa Y, Hoshino S, Tokuda Y, Tamaki K. A 22 year-old female with an unexplained bruising tendency: A case report and review of the literature. Journal of Okinawa Chubu Hospital. 2000;26(2):14-17.

11. Kato J, Tokuda Y. Management and outcome of symptomatic hyponatremia in emergency department. Critical Care. Vol 4; 2000:176.

12. Nakazato N, Kubota S, Takada S, Kinjo S, Tokuda Y. Polymyalgia rheumatica: Three cases with atypical presentation. Journal of Okinawa Chubu Hospital. 2000;26(2):11-13.

13. Nakazato N, Zukeran H, Arata H, Inadome S, Tokuda Y. Severe Hypoxemia associated with Neuroleptic Malignant Syndrome. Journal of Okinawa Chubu Hospital. 2000;26(1):30-33.

14. Nishitarumizu K, Tokuda Y, Uehara H, Taira M, Taira K. Tubulointerstitial nephritis associated with Legionnaires' disease. Internal Medicine. 2000;39(2):150-153.

15. Tokuda Y. Bacterial versus viral meningitis: comparison of the old and the new clinical prediction models. Critical Care. Vol 4; 2000:183.

16. Nakamura Y, Kishaba Y, Masuda T, Nakazato N, Tokuda Y. Neuroleptic Malignant Syndrome in the Patient with Parkinson's disease. Journal of Okinawa Chubu Hospital. 2001;27(1):9-12.

17. Nakazato N, Tokuda Y. Short term Outcomes of Oldest Old Patients. Journal of General Internal Medicine. Vol 16; 2001.

18. Tokuda Y, Miyagi S. Oxygen treatment for acute severe asthma. Home oxygenation would be more effective. BMJ. 2001;323(7320):1069.

19. Tokuda Y, Nakazato N, Maeshiro M, Miyagi S. US-Japan Collaboration in Graduate Medical Education. Journal of General Internal Medicine. Vol 16; 2001.

20. Joishy S, Tokuda Y, Tamaki K. Applied clinical ethics for house staff physicians in Japan: Integral component of end-of-life care. Journal of Okinawa Chubu Hospital. 2002;28(1):25-35.

21. Tokuda Y, Koketsu H. High mortality in hospitalized elderly patients with feeding tube placement. Internal Medicine. 2002;41(8):613-616.

22. Tokuda Y, Nakazato N. Cranial CT before lumbar puncture in suspected meningitis. New England Journal of Medicine. 2002;346(16):1248-1251; author reply 1248-1251.

23. Koketsu H, Tokuda Y, Stein GH. Risk Factors For Mortality From Infectious Diseases Among Elderly From Long-Term Care Facilities. Internet Journal of Infectious Diseases. 2003;2(2):1.

24. Tokuda Y, Kishaba Y, Kato J, Nakazato N. Assessing the validity of a model to identify patients for lymph node biopsy. Medicine (Baltimore). 2003;82(6):414-418.

25. Tokuda Y, Nakazato N, Stein GH. Pupillary evaluation for differential diagnosis of coma. Postgraduate Medical Journal. 2003;79(927):49-51.

26. Tokuda Y, Nakazato N, Tamaki K. Evaluation of end of life care in cancer patients at a teaching hospital in Japan. Journal of Medical Ethics. 2004;30(3):264-267.

27. Kishimoto M, Lim HY, Tokuda Y, Narita M, Kitazono H, Ito H, Seto TB, Sumida KN, Gelber RP. Prevalence of venous thromboembolism at a teaching hospital in Okinawa, Japan. Thrombosis & Haemostasis. 2005;93(5):876-879.

28. Tokuda Y. Risk factors for acute myocardial infarction among Okinawans. Journal of Nutrition, Health, and Aging. 2005;9(4):272-276.

29. Tokuda Y. Ethics and Science of Tobacco Control. Primary Care Japan. 2005;3(1):17-27.

30. Tokuda Y, Miyasato H, Stein GH. A simple prediction algorithm for bacteraemia in patients with acute febrile illness. Quarterly Journal of Medicine. 2005;98(11):813-820.

31. Tokuda Y, Miyasato H, Stein GH, Kishaba T. The degree of chills for risk of bacteremia in acute febrile illness. American Journal of Medicine. 2005;118(12):1417.

32. Tokuda Y, Stein GH. Serum lipids as protective factors for subarachnoid hemorrhage. Journal of Clinical Neuroscience. 2005;12(5):538-541.

33. Tokuda Y. Telemedicine in Okinawa. Okinawa Wellness and Longevity Journal 2006;1(2):1-6.

34. Tokuda Y, Kashima M, Kayo M, Nakazato N, Stein GH. Cocoa supplementation for copper deficiency associated with tube feeding nutrition. Internal Medicine. 2006;45(19):1079-1085.

35. Tokuda Y, Kikuchi M, Takahashi O, Stein GH. Prehospital management of sarin nerve gas terrorism in urban settings: 10 years of progress after the Tokyo subway sarin attack. Resuscitation. 2006;68(2):193-202.

36. Tokuda Y, Matsushima D, Stein GH, Miyagi S. Intrapleural fibrinolytic agents for empyema and complicated parapneumonic effusions: a meta-analysis. Chest. 2006;129(3):783-790.

37. Birrer R, Tokuda Y, Takara T. Hypoxic Hepatopathy: Pathophysiology and Prognosis Internal Medicine. 2007;46(14):1063-1070.

38. Chinen K, Tokuda Y, Sakamoto A, Fujioka Y. Fungal infections of the heart: A clinicopathologic study of 50 autopsy cases. Pathology Research & Practice. 2007;203(10):705-715.

39. Gushiken N, Yoshimura H, Toyoura M, Fujiwara N, Tokuda Y. Severe Retinopathy in Fulminant Juvenile Dermatomyositis. General Medicine. 2007;8(1):25-28.

40. Jacobs JL, Takahashi O, Hirai S, Tokuda Y, Omata F, Fukui T. When fear trumps science: a case study for finding alternative research methods. BMJ. 2007;336:77.

41. Lim H, Kishimoto M, Kitazono H, Ito H, Narita M, Gelber R, Tokuda Y. Risk Factors for Venous Thromboembolism in Japan: A Hospital-Based Case-Control Study. Hawai'i Medical Journal 2007;66:236-239.

42. Morishita K, Gushimiyagi M, Hashiguchi M, Stein GH, Tokuda Y. Clinical prediction rule to distinguish pelvic inflammatory disease from acute appendicitis in women of childbearing age. American Journal of Emergency Medicine. 2007;25(2):152-157.

43. Moromizato T, Harano K, Oyakawa M, Tokuda Y. Diagnostic performance of pyogenic vertebral osteomyelitis. Internal Medicine. 2007;46(1):11-16.

44. Takahashi O, Noguchi Y, Omata F, Tokuda Y, Fukui T. Probiotics in the prevention of traveler's diarrhea: meta-analysis. Journal of Clinical Gastroenterology. 2007;41(3):336-337.

45. Tokuda Y. Cocoa supplementation for copper deficiency. European Journal of Nutraceuticals & Functional Foods (AgroFOOD industry hi-tech). 2007;18(3):11-13.

46. Tokuda Y. Chemical terrorism: Sarin nerve gas and other toxic nerve agents. In: Larche R, ed. Global Terrorism Issues and Developments. New York: Nova Science Publishers; 2007.

47. Tokuda Y, Maezato K, Stein GH. The causes of hypercalcemia in Okinawan patients: an international comparison. Internal Medicine. 2007;46(1):23-28.

48. Tokuda Y, Miyagi S. Physical Diagnosis of Chronic Obstructive Pulmonary Disease. Internal Medicine. 2007;46(28):1885-1891.

49. Tokuda Y, Ohde S, Takahashi O, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. Musculoskeletal pain in Japan: prospective health diary study. Rheumatology International. 2007;28(1):7-14.

50. Tokuda Y, Ohde S, Takahashi O, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. Influence of Socioeconomic Factors on Symptom-Related Access to Health Care. Primary Care Japan. 2007;5(1):12-21.

51. Tokuda Y, Takahashi O, Ohde S, Ogata H, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. Health locus of control and use of conventional and alternative care: a cohort study. British Journal of General Practice. 2007;57(541):643-649.

52. Tokuda Y, Takahashi O, Ohde S, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. Gastrointestinal symptoms in a Japanese population: A health diary study. World Journal of Gastroenterology. 2007;13(4):572-578.

53. Abe T, Ohde S, Ishimatsu S, Ogata H, Hasegawa T, Nakamura T, Tokuda Y. Effects of meteorological factors on the onset of subarachnoid hemorrhage: A time-series analysis. J Clin Neuroscience. 2008;15(9):1005-1010.

54. Abe T, Tokuda Y, Ishimatsu S. A new cardiopulmonary resuscitation method using only rhythmic abdominal compression is hard. American Journal of Emergency Medicine. 2008;26(5):625.

55. Abe T, Tokuda Y, Ishimatsu S. Yubitsume (self-amputation). Emergency Medicine Journal. 2008;25(10):702.

56. Abe T, Tokuda Y, Ohde S, Ishimatsu S, Nakamura T, Birrer R. The influence of meteorological factors on the occurrence of trauma and motor vehicle collisions in Tokyo. Emergency Medicine Journal. 2008;25:769-772.

57. Abe T, Tokuda Y, Stein G, Ishimatsu S, Birrer R. Risk Factors Associated with Prolonged Hospital Stay in Admitted Patients with Psychotropic Drug Overdose. Open Critical Care Medicine Journal. 2008;1(1):12-16.

58. Horinouchi H, Tokuda Y, Nishimura N, Terai M, Takahashi T, Ohde S, Ishikawa R, Fukui T. Influence of Residents' Workload, Mental State and Job Satisfaction on Procedural Error：a prospective daily questionnaire-based study. General Medicine. 2008;9(2):57-64.

59. Jacobs JL, Tokuda Y, Ohde S. Aging policy-makers take note: future physicians are not being taught about healthy longevity. Journal of American Geriatric Society. 2008;56(7):1375-1376.

60. Kowada A, Takahashi O, Shimbo T, Ohde S, Tokuda Y, Fukui T. Cost Effectiveness of Interferon-gamma Release Assay for Tuberculosis Contact Screening in Japan. Mol Diagn Ther. 2008;12(4):235-251.

61. Martins H, Tokuda Y, Fukui T. Management matters. Igaku Kyoiku. 2008;39(6):411-416.

62. Norisue Y, Tokuda Y, Koizumi M, Kishaba T, Miyagi S. Phasic characteristics of inspiratory crackles of bacterial and atypical pneumonia. Postgrad Med J. 2008;84(994):432-436.

63. Ohde S, Takahashi O, Jacobs J, Tokuda Y, Omata F, Hinohara S, Fukui T. Japanese medical residents' self-assessed confidence in clinical research: skills improve with experience in scholarly activities. General Medicine. 2008;9:81-82.

64. Ohde S, Tokuda Y, Takahashi O, Yanai H, Hinohara S, Fukui T. Dysmenorrhea among Japanese women. International Journal of Gynecology & Obstetrics. 2008;100(1):13-17.

65. Omata F, Sato S, Tokuda Y, Takahashi O, Fukui T. Autoimmune hemolytic anemia associated with primary biliary cirrhosis. General Medicine. 2008;9:65-70.

66. Ono R, Higashi T, Suzukamo Y, Konno S, Takahashi O, Tokuda Y, Rhaman M, Shimbo T, Endo H, Hinohara S, Fukui T, Fukuhara S. Higher internality of health locus of control is associated with the use of complementary and alternative medicine providers among patients seeking care for acute low-back pain. Clin J Pain. 2008;24(8):725-730.

67. Tokuda Y, Hinohara S. Redefining the age of elderly in Japan. Journal of the American Geriatrics Society. 2008;56(3):573-574.

68. Tokuda Y, Hinohara S. Geriatric Nation and Redefining the Elderly in Japan. International Journal of Gerontology. 2008;2(4):154-157.

69. Tokuda Y, Hinohara S, Fukui T. Introducing a new medical school system into Japan. Ann Acad Med Singapore. 2008;37(9):800-802.

70. Tokuda Y, Inoguchi T. Trust in the Mass Media and the Healthcare System, Interpersonal Trust and Self-Rated Health: A Population-based Study in Japan. Asian Journal of Epidemiology. 2008;1(1):29-39.

71. Tokuda Y, Inoguchi T. Interpersonal Mistrust and Unhappiness Among Japanese People. Social Indicators Research. 2008;89(2):349-360.

72. Tokuda Y, Jimba M, Yanai H, Fujii S, Inoguchi T. Interpersonal trust and quality-of-life: a cross-sectional study in Japan. PLoS ONE. 2008;3(12):e3985.

73. Tokuda Y, Obara H, Nakazato N, Stein GH. Acute care hospital mortality of schizophrenic patients. Journal of Hospital Medicine. 2008;3(2):110-116.

74. Tokuda Y, Ohde S, Takahashi O, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. Prospective health diary study for new onset chest symptoms in the Japanese general population. Internal Medicine. 2008;47(1):25-31.

75. Tokuda Y, Ohde S, Takahashi O, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. Relationships between Working Status and Health or Healthcare Utilization among Japanese Elderly. Geriatrics & Gerontology International. 2008;8(1):32-40.

76. Tokuda Y, Okamoto S, Yoshioka Y, Aizawa M, Tanaka M, Motomura K, Hayano K. The influence of medical jargon mixed with foreign terminology in the Japanese clinical environment. Internal Medicine. 2008;47(14):1329-1334.

77. Tokuda Y, Takahashi O, Ohde S, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. Sociodemographic Characteristics for Use of Complementary and Alternative Medicine in Japan. General Medicine. 2008;9(1):31-39.

78. Tokuda Y, Yoshioka Y, Aizawa M, Tanaka M, Ohde S, Motomura K, Naito A, Hayano K, Fukui T. Physicians' Use of Local Dialects during Communication with Patients. General Medicine. 2008;9(1):13-19.

79. Abe T, Nagamine Y, Ishimatsu S, Tokuda Y. Spinal epidural hematoma after stretch exercise: a case report. Am J Emerg Med. 2009;27(7):902 e901-902.

80. Abe T, Tokuda Y, Ishimatsu S. Predictors for good cerebral performance among adult survivors of out-of-hospital cardiac arrest. Resuscitation. 2009;80(4):431-436.

81. Abe T, Tokuda Y, Ishimatsu S, Birrer RB. Usefulness of initial blood cultures in patients admitted with pneumonia from an emergency department in Japan. J Infect Chemother. 2009;15(3):180-186.

82. Abe T, Tokuda Y, Ohde S, Ishimatsu S, Nakamura T, Birrer RB. The relationship of short-term air pollution and weather to ED visits for asthma in Japan. Am J Emerg Med. 2009;27(2):153-159.

83. Chinen K, Tokuda Y, Aoki M. Clinical Problem Solving : Diagnostic Power of Gram Stain Examination. General Medicine. 2009;10:3-6.

84. Jacobs JL, Ohde S, Takahashi O, Tokuda Y, Omata F, Fukui T. Use of surgical face masks to reduce the incidence of the common cold among health care workers in Japan: A randomized controlled trial. Am J Infect Control. 2009;37(5):417-419.

85. Jacobs JL, Takahashi O, Ohde S, Tokuda Y, Omata F, Fukui T. PDA Usage by Japanese Resident Physicians Is Low. Methods Inf Med. 2009;48(4):475-479.

86. Kiyoyama T, Tokuda Y, Shiiki S, Hachiman T, Shimasaki T, Endo K. Isopropyl alcohol compared with isopropyl alcohol plus povidone-iodine as skin preparation for prevention of blood culture contamination. J Clin Microbiol. 2009;47(1):54-58.

87. Norisue Y, Onopa J, Kaneshiro M, Tokuda Y. Surfing as a risk factor for gastroesophageal reflux disease. Clin J Sport Med. 2009;19(5):388-393.

88. Omata F, Brown WR, Tokuda Y, Takahashi O, Fukui T, Ueno F, Mine T. Modifiable risk factors for colorectal neoplasms and hyperplastic polyps. Internal Medicine. 2009;48(3):123-128.

89. Omata F, Shibata M, Nakano M, Jacobs JL, Tokuda Y, Fukutake K, Takahashi O, Fukui T. Chronic hepatitis with eosinophilic infiltration associated with asthma. Internal Medicine. 2009;48(22):1945-1949.

90. Takahashi O, Ohde S, Jacobs JL, Tokuda Y, Omata F, Fukui T. Residents' experience of scholarly activities is associated with higher satisfaction with residency training. J Gen Intern Med. 2009;24(6):716-720.

91. Tokuda Y, Aoki M, Kandpal SB, Tierney LM, Jr. Caught in the web: e-diagnosis. J Hosp Med. 2009;4(4):262-266.

92. Tokuda Y, Barnett PB, Norisue Y, Konishi R, Kudo H, Miyagi S. Questionnaire survey for challenging cases of medical professionalism in Japan. Medical Teacher. 2009;31(6):502-507.

93. Tokuda Y, Chinen K, Obara H, Joishy SK. Intervals between Symptom Onset and Clinical Presentation in Cancer Patients. Internal Medicine. 2009;48(11):899-905.

94. Tokuda Y, Doba N, Butler JP, Paasche-Orlow MK. Health literacy and physical and psychological wellbeing in Japanese adults. Patient Educ Couns. 2009;75(3):411-417.

95. Tokuda Y, Fujii S, Jimba M, Inoguchi T. The relationship between trust in mass media and the healthcare system and individual health: evidence from the AsiaBarometer Survey. BMC Medicine. 2009;7(1):4.

96. Tokuda Y, Hayano K, Ozaki M, Bito S, Yanai H, Koizumi S. The interrelationships between working conditions, job satisfaction, burnout and mental health among hospital physicians in Japan: a path analysis. Industrial Health. 2009;47(2):166-172.

97. Tokuda Y, Koizumi M, Stein GH, Birrer RB. Identifying low-risk patients for bacterial meningitis in adult patients with acute meningitis. Internal Medicine. 2009;48(7):537-543.

98. Tokuda Y, Ohde S, Takahashi O, Hinohara S, Fukui T, Inoguchi T, Butler JP, Ueda S. Influence of Income on Health Status and Healthcare Utilization in Working Adults: an Illustration of Health among the Working Poor in Japan. Japanese Journal of Political Science. 2009;10(1):79-92.

99. Tokuda Y, Okubo T, Ohde S, Jacobs J, Takahashi O, Omata F, Yanai H, Hinohara S, Fukui T. Assessing Items on the SF-8 Japanese Version for Health-Related Quality of Life: A Psychometric Analysis Based on the Nominal Categories Model of Item Response Theory. Value in Health. 2009;12(4):568-573.

100. Tsugawa Y, Tokuda Y, Ohbu S, Okubo T, Cruess R, Cruess S, Ohde S, Okada S, Hayashida N, Fukui T. Professionalism Mini-Evaluation Exercise for medical residents in Japan: a pilot study. Medical Education. 2009;43(10):968-978.

101. Tsunoda Y, Kondo T, Matsuda Y, Kobayashi H, Tokuda Y, Satoh H. A Key Film. J Emerg Med. 2009.

102. Yamamoto Y, Yamazaki S, Hayashino Y, Takahashi O, Tokuda Y, Shimbo T, Fukui T, Hinohara S, Miyachi Y, Fukuhara S. Association between frequency of pruritic symptoms and perceived psychological stress: a Japanese population-based study. Arch Dermatol. 2009;145(12):1384-1388.

103. Chinen K, Tokuda Y, Fujiwara M, Fujioka Y. Pulmonary tumor thrombotic microangiopathy in patients with gastric carcinoma: An analysis of 6 autopsy cases and review of the literature. Pathol Res Pract. 2010;206(10):682-689.

104. Komatsu I, Tokuda Y, Shimada G, Jacobs JL, Onodera H. Development of a simple model for predicting need for surgery in patients who initially undergo conservative management for adhesive small bowel obstruction. Am J Surg. 2010;200(2):215-223.

105. Nishizaki Y, Tokuda Y, Sato E, Kato K, Matsumoto A, Takekata M, Terai M, Watanabe C, Lim Y, Ohde S, Ishikawa R. Relationship between nursing workloads and patient safety incidents. Journal of Multidisciplinary Healthcare. 2010;3:49-54.

106. Omata F, Deshpande G, Tokuda Y, Takahashi O, Ohde S, Carr-Locke DL, Jacobs JL, Mine T, Fukui T. Meta-analysis: somatostatin or its long-acting analogue, octreotide, for prophylaxis against post-ERCP pancreatitis. J Gastroenterol. 2010;45(8):885-895.

107. Sakamoto F, Yamada H, Suzuki C, Sugiura H, Tokuda Y. Increased use of alcohol-based hand sanitizers and successful eradication of methicillin-resistant Staphylococcus aureus from a neonatal intensive care unit: A multivariate time series analysis. Am J Infect Control. 2010;38(7):529-534.

108. Shimizu T, Tokuda Y. Necrotizing fasciitis. Internal Medicine. 2010;49(12):1051-1057.

109. Stein GH, Shibata A, Bautista M, Tokuda Y. Webinar: An interactive Clinical Seminars for Japanese Medical Students. General Medicine. 2010;11(2):87-90.

110. Takahashi O, Ohde S, Jacobs JL, Tokuda Y, Yanai H, Okubo T, Shimbo T, Fukuhara S, Hinohara S, Fukui T. Population-level preferences for primary care physicians' characteristics in Japan: a structural equation modeling. Internal Medicine. 2010;49(2):125-130.

111. Tokuda Y, Abe T, Ishimatsu S, Hinohara S. Ambulance Transport of the Oldest Old in Tokyo: A Population-Based Study. J Epidemiol. 2010;20(6):468-472.

112. Tokuda Y, Goto E, Otaki E, Jacobs JL, Omata F, Shapiro M, Soejima K, Ishida Y, Ohde S, Takahashi O, Fukui T. Educational environment of university and non-university hospitals in Japan International Journal of Medical Education. 2010;1:10-14.

113. Tokuda Y, Goto E, Otaki J, Jacobs J, Omata F, Obara H, Shapiro M, Soejima K, Ishida Y, Ohde S, Takahashi O, Fukui T. Undergraduate educational environment, perceived preparedness for postgraduate clinical training, and pass rate on the National Medical Licensure Examination in Japan. BMC Medical Education. 2010;10(1):35-44.

114. Tokuda Y, Okubo T, Yanai H, Doba N, Paasche-Orlow MK. Development and Validation of a 15-Item Japanese Health Knowledge Test. J Epidemiol. 2010;20(4):319-328.

115. Tokuda Y, Okubo T, Yanai H, Jacobs J, Ohde S, Takahashi O, Omata F, Hinohara S, Fukui T. Comparison of health locus of control between physicians and the general public. Health Education Journal. 2010;69(1):63-73.

116. Tokuda Y, Omata F, Tsugawa Y, Maesato K, Momotura K, Fujinuma A, Stein GH, Cook EF. Vital sign triage to rule out diabetic ketoacidosis and non-ketotic hyperosmolar syndrome in hyperglycemic patients. Diabetes Res Clin Pract. 2010;87(3):366-371.

117. Abe T, Tokuda Y. Chest-compression-only versus standard CPR. Lancet. 2011;377(9767):718.

118. Abe T, Tokuda Y, Cook EF. Time-based partitioning model for predicting neurologically favorable outcome among adults with witnessed bystander out-of-hospital CPA. PLoS ONE. 2011;6(12):e28581.

119. Abe T, Tokuda Y, Ishimatsu S, Stein GH. Spinal dural arteriovenous fistula incidentally discovered. J Emerg Trauma Shock. 2011;4(2):299.

120. Alkhatib L, Albtoush O, Bataineh N, Gharaibeh K, Matalka I, Tokuda Y. Extragastrointestinal Stromal Tumor (EGIST) in the abdominal wall: Case report and literature review. Int J Surg Case Rep. 2011;2(8):253-255.

121. Arima T, Nagamine Y, Obara H, Tokuda Y. Clinical Problem Solving: A repetitive visitor to the emergency room. General Medicine. 2011;12(1):5-10.

122. Kondo Y, Abe T, Kohshi K, Tokuda Y, Cook EF, Kukita I. Revised trauma scoring system to predict in-hospital mortality in the emergency department: Glasgow Coma Scale, age and systolic blood pressure score. Crit Care. 2011;15(4):R191.

123. Ohde S, Hayashi A, Takahasi O, Yamakawa S, Nakamura M, Osawa A, Shapiro ML, Deshpande GA, Tokuda Y, Omata F, Ishida Y, Soejima K, Hinohara S, Fukui T. A 2-week prognostic prediction model for terminal cancer patients in a palliative care unit at a Japanese general hospital. Palliat Med. 2011;25(2):170-176.

124. Ono R, Higashi T, Takahashi O, Tokuda Y, Shimbo T, Endo H, Hinohara S, Fukui T, Fukuhara S. Sex differences in the change in health-related quality of life associated with low back pain. Qual Life Res. 2011;21(10):1705-1711.

125. Sato K, Yamazaki S, Hayashino Y, Takegami M, Tokuda Y, Takahashi O, Shimbo T, Hinohara S, Fukui T, Fukuhara S. Associations between Hours Worked, Symptoms and Health Resource Utilization among Full-time Male Japanese Workers. J Occup Health. 2011;53(3):197-204.

126. Shimizu T, Tokuda Y. Acute urinary retention. Internal Medicine. 2011;50(19):2255.

127. Takahashi Y, Sakai M, Tokuda Y, Takahashi O, Ohde S, Nakayama T, Fukuhara S, Fukui T, Shimbo T. The relation between self-reported body weight and health-related quality of life: a cross-sectional study in Japan. J Public Health (Oxf). 2011;33(4):518-526.

128. Tokuda Y. Benchmarking the Age of Elderly in Japan. General Medicine. 2011;12(1):3-4.

129. Tokuda Y, Goto E, Otaki J, Omata F, Shapiro M, Soejima K, Ishida Y, Ohde S, Takahashi O, Fukui T. The New Japanese Postgraduate Medical Education and Quality of Emergency Medical Care. J Emerg Med. 2011;43(3):494-501.

130. Tokuda Y, Kishida N, Konishi R, Koizumi S. Cognitive error as the most frequent contributory factor in cases of medical injury: A study on verdict's judgment among closed claims in Japan. J Hosp Med. 2011;6(3):109-114.

131. Tsugawa Y, Ohbu S, Cruess R, Cruess S, Okubo T, Takahashi O, Tokuda Y, Heist BS, Bito S, Itoh T, Aoki A, Chiba T, Fukui T. Introducing the Professionalism Mini-Evaluation Exercise (P-MEX) in Japan: Results From a Multicenter, Cross-Sectional Study. Acad Med. 2011;86(8):1026-1031.

132. Yoshida K, Tokuda Y, Oshikawa H, Utsunomiya M, Kobayashi T, Kimura M, Deshpande GA, Matsui K, Kishimoto M. An observational study of tocilizumab and TNF-{alpha} inhibitor use in a Japanese community hospital: different remission rates, similar drug survival and safety. Rheumatology (Oxford). 2011;50(11):2093-2099.

133. Abe T, Fujihara K, Kono M, Kumagai R, Ono K, Tokuda Y. Clinical Problem Solving: What Causes Tachycardia in a Hip Injury? General Medicine. 2012;13(1):5-10.

134. Abe T, Tokuda Y, Kitahara T, Sakai S, Toyama M, Watanabe S. Syncope Caused by Portopulmonary Hypertension : A Case Report General Medicine. 2012;13(2):113-116.

135. Barata AN, Tokuda Y, Martins HM. Comparing healthcare systems: Considering Japan and Portugal. Revista Portuguesa de Saude Publica. 2012.

136. Doba N, Tokuda Y, Goldstein NE, Kushiro T, Hinohara S. A pilot trial to predict frailty syndrome: The Japanese Health Research Volunteer Study. Exp Gerontol. 2012;47(8):638-643.

137. Hayashi N, Nakamura S, Tokuda Y, Shimoda Y, Yagata H, Yoshida A, Ota H, Hortobagyi GN, Cristofanilli M, Ueno NT. Prognostic value of HER2-positive circulating tumor cells in patients with metastatic breast cancer. Int J Clin Oncol. 2012;17(2):96-104.

138. Hayashi N, Nakamura S, Tokuda Y, Yagata H, Yoshida A, Ota H, Hortobagyi GN, Cristofanilli M, Ueno NT. Serum HER2 levels determined by two methods in patients with metastatic breast cancer. Int J Clin Oncol. 2012;17(1):55-62.

139. Imanishi M, Sato M, Tokuda Y. Endoscopic capture of Anisakis larva (a video demonstration). BMJ Case Rep. 2012;2012.

140. Ishimaru N, Suzuki H, Tokuda Y, Takano T. Severe Legionnaires' Disease with Pneumonia and Biopsy-Confirmed Myocarditis Most Likely Caused by Legionella pneumophila Serogroup 6. Internal Medicine. 2012;51(22):3207-3212.

141. Kato M, Seyama Y, Kanai T, Fujiwara K, Omoto M, Moriyama N, Nishiki K, Tokuda Y. Clinical Problem Solving : Masked Face of Posterior Illness General Medicine. 2012;13(2):65-68.

142. Kimura M, Tokuda Y, Oshiawa H, Yoshida K, Utsunomiya M, Kobayashi T, Deshpande GA, Matsui K, Kishimoto M. Clinical characteristics of patients with remitting seronegative symmetrical synovitis with pitting edema compared to patients with pure polymyalgia rheumatica. J Rheumatol. 2012;39(1):148-153.

143. Nishizaki Y, Watanabe T, Tokuda Y, Futatsuyama M, Furukawa K, Mori N, Tsugawa Y, Yuki H, Tamagaki K, Taki F. Renal Function and Mortality in Patients with Infective Endocarditis. General Medicine. 2012;13(1):19-24.

144. Shimizu M, Kinoshita K, Hattori K, Ota Y, Kanai T, Kobayashi H, Tokuda Y. Physical signs of dehydration in the elderly. Internal Medicine. 2012;51(10):1207-1210.

145. Shimizu T, Kinoshita K, Tokuda Y. Diphyllobothrium nihonkaiense infection linked to chilled salmon consumption. BMJ Case Rep. 2012;2012.

146. Shimizu T, Tokuda Y. Exercise-induced anaphylaxis. BMJ Case Rep. 2012;2012.

147. Shimizu T, Tokuda Y. Hairy tongue. BMJ Case Rep. 2012;2012.

148. Shimizu T, Tokuda Y. System 3 diagnostic process: the lateral approach. International Journal of General Medicine. 2012;5:873-874.

149. Shimizu T, Tokuda Y. Pivot and cluster strategy: a preventive measure against diagnostic errors. International Journal of General Medicine. 2012;5:917-921.

150. Shimizu T, Tokuda Y. Superior mesenteric artery dissection. BMJ Case Rep. 2012;2012.

151. Shimizu T, Tokuda Y. Real-world medical diagnosis: Intuitive process revisited (review). International Journal of Medicine and Medical Sciences. 2012;4(9):177-179.

152. Shimizu T, Tokuda Y. Miller Fisher syndrome linked to Norovirus infection. BMJ Case Rep. 2012;2012.

153. Tokuda Y. Case 23-2012: A man with abdominal pain and weight loss. N Engl J Med. 2012;367(17):1670; author reply 1671-1672.

154. Tokuda Y. Re: When financial incentives do more good than harm: a checklist. BMJ. 2012;345:e5047.

155. Abe T, Ishimatsu S, Tokuda Y. Descriptive analysis of patients' EMS use related to severity in Tokyo: a population-based observational study. PLoS One. 2013;8(3):e59738.

156. Abe T, Tokuda Y. Bilateral carotid arteries occlusion. BMJ case reports. 2013;2013.

157. Abe T, Tokuda Y. The Triage in a Mild and Mini Disaster General Medicine. 2013;14(1):76-77.

158. Abe T, Watanabe S, Mizuno A, Toyama M, Tokuda Y. A Model for Predicting Angiographically Normal Coronary Arteries in Survivors of Out of Hospital Cardiac Arrest. Circulation. 2013;128(22 Supplement):A122.

159. Doba N, Tokuda Y, Tomiyama H, Goldstein NE, Kushiro T, Hinohara S. Changes in ankle brachial pulse wave velocity during a five-year follow-up period in older Japanese adults: sub-analysis results of the health research volunteer study in Japan. Internal Medicine. 2013;52(1):21-27.

160. Itoi S, Tokuda Y, Ohara G, Kagohashi K, Satoh H. Acute Eosinophilic Pneumonia in a Teenager as a Result of Smoking : Importance of Differential Diagnosis General Medicine. 2013;14(1):64-66.

161. Kinoshita K, Hattori K, Ota Y, Kanai T, Shimizu M, Kobayashi H, Tokuda Y. The measurement of axillary moisture for the assessment of dehydration among older patients: a pilot study. Exp Gerontol. 2013;48(2):255-258.

162. Kinoshita K, Tsunoda Y, Watanabe S, Tokuda Y. Spontaneous coronary artery dissection in a patient with bacterial meningitis. BMJ Case Rep. 2013;2013.

163. Kobayashi H, Suzuki T, Tokuda Y. Pyogenic ventriculitis following urosepsis caused by Escherichia coli. BMJ Case Rep. 2013;2013.

164. Kobayashi T, Kishimoto M, Swearingen CJ, Filopoulos MT, Ohara Y, Tokuda Y, Oshikawa H, Yoshida K, Utsunomiya M, Kimura M, Okada M, Matsui K, Yazici Y. Differences in clinical manifestations, treatment, and concordance rates with two major sets of criteria for Behcet's syndrome for patients in the US and Japan: data from a large, three-center cohort study. Mod Rheumatol. 2013;23(3):547-553.

165. Miyauchi R, Kinoshita K, Tokuda Y. Clarithromycin-induced haemorrhagic colitis. BMJ Case Rep. 2013;2013.

166. Sakakura K, Takayashiki N, Tokuda Y, Satoh H. Biliary tract compression caused by a giant abdominal aneurysm. Internal Medicine. 2013;52(8):925.

167. Sawa A, Abe T, Omoto M, Fujiwara K, Kobayashi H, Tokuda Y. Lactic Acidosis with Metformin Use in a Patient with Type 1 Diabetes Mellitus General Medicine. 2013;14(1):72-75.

168. Shimizu T, Matsumoto K, Tokuda Y. Effects of the use of differential diagnosis checklist and general de-biasing checklist on diagnostic performance in comparison to intuitive diagnosis. Med Teach. 2013;35(6):e1218-1229.

169. Shimizu T, Nozaki H, Tokuda Y. Steinert's disease. BMJ Case Rep. 2013;2013.

170. Shimizu T, Tokuda Y. Osler's node. BMJ case reports. 2013;2013.

171. Shimizu T, Tokuda Y. Intravesical migration of intrauterine device. BMJ case reports. 2013;2013.

172. Shimizu T, Tokuda Y. Visible intestinal peristalsis. BMJ Case Rep. 2013;2013.

173. Shimizu T, Tsugawa Y, Tanoue Y, Konishi R, Nishizaki Y, Kishimoto M, Shiojiri T, Tokuda Y. The hospital educational environment and performance of residents in the General Medicine In-Training Examination: a multicenter study in Japan. Int J Gen Med. 2013;6:637-640.

174. Suzuki H, Senda J, Yamashita K, Tokuda Y, Kanesaka Y, Kotaki N, Ishihara H, Ishikawa H. Impact of intensive infection control team activities on the acquisition of methicillin-resistant Staphylococcus aureus, drug-resistant Pseudomonas aeruginosa and the incidence of Clostridium difficile-associated disease. J Infect Chemother. 2013;19(6):1047-1052.

175. Suzuki H, Shichi D, Tokuda Y, Ishikawa H, Maeno T, Nakamura H. Pneumococcal vertebral osteomyelitis at three teaching hospitals in Japan, 2003-2011: analysis of 14 cases and a review of the literature. BMC Infect Dis. 2013;13:525.

176. Suzuki H, Tokuda Y, Kurihara Y, Suzuki M, Nakamura H. Adult pneumococcal meningitis presenting with normocellular cerebrospinal fluid: two case reports. J Med Case Rep. 2013;7(1):294.

177. Suzuki H, Tokuda Y, Shichi D, Hitomi S, Ishikawa H, Maeno T, Nakamura H. A retrospective cohort study of panipenem/betamipron for adult pneumococcal bacteremia at three teaching hospitals in Japan. J Infect Chemother. 2013;19(4):607-614.

178. Suzuki H, Tokuda Y, Shichi D, Ishikawa H, Maeno T, Nakamura H. Morbidity and mortality among newly hospitalized patients with community-acquired pneumococcal bacteremia: A retrospective cohort study in three teaching hospitals in Japan. Geriatr Gerontol Int. 2013;13(3):607-615.

179. Takata Y, Stein GH, Endo K, Arai A, Kohsaka S, Kitano Y, Honda H, Kitazono H, Tokunaga H, Tokuda Y, Obika M, Miyoshi T, Kataoka H, Terasawa H. Content analysis of medical students' seminars: a unique method of analyzing clinical thinking. BMC Med Educ. 2013;13:156.

180. Tokuda Y, Feldman MD. Direct to consumer unproved screening tests turn a profit in Japan. BMJ. 2013;347:f4725.

181. Abe T, Takahashi O, Saitoh D, Tokuda Y. Association between helicopter with physician versus ground emergency medical services and survival of adults with major trauma in Japan. Crit Care. 2014;18(4):R146.

182. Abe T, Tokuda Y. Recurrent posterior reversible encephalopathy syndrome of the brainstem in a hypertensive patient with end-stage renal disease. J Emerg Trauma Shock. 2014;7(3):242-243.

183. Chuganji E, Abe T, Kobayashi H, Nakano N, Kanai T, Ohara G, Takayashiki N, Noguchi M, Morishita Y, Aoki M, Tokuda Y. Fatal pulmonary co-infection with pneumocystis and cytomegalovirus in a patient with acquired immunodeficiency syndrome. Internal Medicine. 2014;53(14):1575-1578.

184. Fushiki Y, Kinoshita K, Tokuda Y. Polypharmacy and Adverse Drug Events Leading to Acute Care Hospitalization in Japanese Elderly General Medicine. 2014;15(2):110-116.

185. Hamano J, Tokuda Y. Inappropriate Prescribing Among Elderly Home Care Patients in Japan: Prevalence and Risk Factors. J Primary Care Community Health. 2014;5(2):90-96.

186. Hamano J, Tokuda Y. Risk Factors and Specific Prescriptions Related to Inappropriate Prescribing among Japanese Elderly Home Care Patients General Medicine. 2014;15(2):117-125.

187. Hosoi T, Dhaliwal G, Tokuda Y. Amyloidosis in bilateral external auditory canals. BMJ Case Rep. 2014;2014.

188. Iriyama H, Kato M, Nogami M, Tokuda Y. Edamame (green soy beans) biliary stones. BMJ Case Rep. 2014;2014.

189. Kamata K, Tokuda Y. Rapid diagnosis of Campylobacter jejuni by stool Gram stain examination. BMJ Case Rep. 2014;2014.

190. Matsuoka R, Takayashiki N, Chino Y, Tokuda Y. Fatal Full-blown Systemic Lupus Erythematosus. Internal Medicine. 2014;53(15):1733-1734.

191. Nakano H, Watari T, Suganami Y, Tokuda Y. A navel stone mimicking a urachal sinus. BMJ Case Rep. 2014;2014.

192. Nishiguchi S, Branch J, Suganami Y, Kitagawa I, Tokuda Y. Effectiveness of early ureteric stenting for urosepsis associated with urinary tract calculi. Internal Medicine. 2014;53(19):2205-2210.

193. Sakamoto F, Sakihama T, Saint S, Greene MT, Ratz D, Tokuda Y. Health care-associated infection prevention in Japan: The role of safety culture. Am J Infect Control. 2014;42(8):888-893.

194. Sakihama T, Honda H, Saint S, Fowler KE, Shimizu T, Kamiya T, Sato Y, Arakawa S, Lee JJ, Iwata K, Mihashi M, Tokuda Y. Hand Hygiene Adherence Among Health Care Workers at Japanese Hospitals: A Multicenter Observational Study in Japan. J Patient Saf. 2014;12(1):11-17.

195. Shimizu T, Yamamoto Y, Hosoi T, Kinoshita K, Tokuda Y. MRSA toxic shock syndrome associated with surgery for left leg fracture and co-morbid compartment syndrome. Journal of Acute Disease. 2014;3(1):82-84.

196. Stein GH, Tokunaga H, Ando H, Obika M, Miyoshi T, Tokuda Y, Bautista M, Kataoka H, Terasawa H. Preliminary report of a Web-based instrument to assess and teach knowledge and clinical thinking to medical student. Int J Med Educ. 2014;5:1-6.

197. Suzuki T, Tokuda Y. Face the truth: a 76-year-old man with chronic heart failure of unknown origin. BMJ Case Rep. 2014;2014.

198. Tokuda Y. Case 38-2013: A man with fever and lymphadenopathy. N Engl J Med. 2014;370(11):1076-1077.

199. Tokuda Y. Young Japanese Generalist Physicians, Be Academic! A Message from the New Editor-in-Chief of General Medicine General Medicine. 2014;15(2):85-87.

200. Watanabe T, Tokuda Y. Small bowel obstruction following the consumption of "sushi". Internal Medicine. 2014;53(22):2661-2662.

201. Watanuki S, Kinoshita K, Oda A, Kobayashi H, Satoh H, Tokuda Y. Occam's Razor or Hickam's dictum: a paraneoplastic or coincidental occurrence of lung cancer and Guillain-Barre syndrome. Internal Medicine. 2014;53(14):1569-1573.

202. Watanuki S, Kinoshita K, Tokuda Y. Acute graft occlusion of abdominal aorta after anaphylaxis. BMJ Case Rep. 2014;2014.

203. Watari T, Shimizu T, Tokuda Y. Broca aphasia. BMJ Case Rep. 2014;2014.

204. Watari T, Shimizu T, Tokuda Y. Rupture of megadolicho basilar artery anomaly. BMJ Case Rep. 2014;2014.

205. Watari T, Terashima T, Tokuda Y. Coeliac artery compression syndrome as a cause of abdominal pain of unknown origin. BMJ Case Rep. 2014;2014.

206. Abe T, Tamiya N, Kitahara T, Tokuda Y. Polypharmacy as a risk factor for hospital admission among ambulance‐transported old‐old patients. Acute Medicine & Surgery. 2015;3(2):107–113.

207. Abe T, Tokuda Y, Watanabe S. Eight-vessel disease mimicking takotsubo cardiomyopathy. QJM. 2015.

208. Abe T, Watanabe S, Mizuno A, Toyama M, Totten VY, Tokuda Y. A model for predicting angiographically normal coronary arteries in survivors of out-of-hospital cardiac arrest. J Intensive Care. 2015;3(1):32.

209. Hamano J, Ozone S, Tokuda Y. A comparison of estimated drug costs of potentially inappropriate medications between older patients receiving nurse home visit services and patients receiving pharmacist home visit services: a cross-sectional and propensity score analysis. BMC health services research. 2015;15(1):73.

210. Horiuchi M, Tokuda Y, Tagashira Y, Higuchi M, Honda H. Impact of Infectious Disease Consultation and Prospective Carbapenem Audit as an Antimicrobial Stewardship for Carbapenem Use at a Japanese Tertiary Care Center: An Interrupted Time Series Analysis. Paper presented at: Open Forum Infectious Diseases, 2015.

211. Kamata K, Suzuki H, Kanemoto K, Tokuda Y, Shiotani S, Hirose Y, Suzuki M, Ishikawa H. Clinical evaluation of the need for carbapenems to treat community-acquired and healthcare-associated pneumonia. Journal of Infection and Chemotherapy. 2015.

212. Katayama K, Suzuki M, Seki Y, Mori N, Kanai T, Tokuda Y. Causes of New Onset Fever among Hospitalized Patients and Predictors for In-Hospital Mortality in a Teaching Hospital in Japan. General Medicine. 2015;16(2):84-89.

213. Katayama K, Tokuda Y. Inter-arm Blood Pressure Difference by Takayasu’s Arteritis. General Medicine. 2015;16(1):45.

214. Katayama K, Tokuda Y. Severe Paresthesia as a Rare Presenting Symptom of Subacute Thyroiditis. General Medicine. 2015;16(1):26-28.

215. Kato M, Chino Y, Sato R, Kinoshita K, Tsuji H, Tokuda Y, Tamaoka A, Sumida T. Lateral medullary infarction in a patient with central nervous system lupus. International journal of rheumatic diseases. 2015.

216. Kato M, Oishi Y, Inada M, Tokuda Y. Advanced Erosive Gout as a Cause of Fever of Unknown Origin. Korean journal of family medicine. 2015;36(3):146-149.

217. Kinoshita K, Tsugawa Y, Barnett PB, Tokuda Y. Challenging cases of professionalism in Japan: improvement in understanding of professional behaviors among Japanese residents between 2005 and 2013. BMC medical education. 2015;15(1):42.

218. Kinoshita K, Tsugawa Y, Shimizu T, Tanoue Y, Konishi R, Nishizaki Y, Shiojiri T, Tokuda Y. Impact of inpatient caseload, emergency department duties, and online learning resource on General Medicine In-Training Examination scores in Japan. Int J Gen Med. 2015;8:355-360.

219. Miyata H, Ezoe S, Hori M, Inoue M, Oguro K, Okamoto T, Onishi K, Onozaki K, Sakakibara T, Takeuchi K, Tokuda Y, Yamamoto Y, Yamazaki M, Shibuya K, Health Care Advisory P. Japan's vision for health care in 2035. Lancet. 2015;385(9987):2549-2550.

220. Miyauchi R, Matsuda Y, Tokuda Y. Urinary Tract Infection as a Cause of Hyperammonemic Encephalopathy. General Medicine. 2015;16(2):95-98.

221. Miyauchi R, Tokuda Y. A Rare Case of Obsessive-Compulsive Disorder with Symptoms of Unexplained Somatic and Memory Problem. General Medicine. 2015;16(1):33-36.

222. Sakihama T, Honda H, Saint S, Fowler KE, Kamiya T, Sato Y, Iuchi R, Tokuda Y. Improving healthcare worker hand hygiene adherence before patient contact: A multimodal intervention of hand hygiene practice in Three Japanese tertiary care centers. J Hosp Med. 2015;11(3):199-205.

223. Satake S, Kaneko S, Yokozawa I, Shibasaki M, Mita O, Takase M, Miyashita S, Fujita Y, Stelling J, Tokuda Y. Clinical Usefulness of Multi-facility Microbiology Laboratory Database Analysis by WHONET. Journal of General and Family Medicine. 2015;16(3):138-142.

224. Shinotsuka M, Shirai S, Tokuda Y. Deep Vein Thrombosis due to Metastatic Bladder Cancer. Internal Medicine. 2015;54(19):2527-2528.

225. Stein GH, Tokunaga H, Ando H, Obika M, Miyoshi T, Tokuda Y, Noguchi Y, Kataoka H, Terasawa H. Medical Students' Opinion of a Web-based Module to Teach Clinical Reasoning and Knowledge. General Medicine. 2015;16(2):76-83.

226. Stein GH, Tokunaga H, Ando H, Obika M, Miyoshi T, Tokuda Y, Noguchi Y, Kinjo M, Kohsaka S, Honda H. Clinical reasoning Web-based prototypic module for tutors teaching 5th grade medical students: a pilot randomized study. General Medicine. 2015;16(1):13-25.

227. Suzuki H, Hitomi S, Yaguchi Y, Tamai K, Ueda A, Kamata K, Tokuda Y, Koganemaru H, Kurihara Y, Ishikawa H. Prospective intervention study with a microarray-based, multiplexed, automated molecular diagnosis instrument (Verigene system) for the rapid diagnosis of bloodstream infections, and its impact on the clinical outcomes. Journal of Infection and Chemotherapy. 2015;21(12):849-856.

228. Terada N, Kinoshita K, Taguchi S, Tokuda Y. Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient. BMJ Case Rep. 2015;2015.

229. Terada N, Tanaka T, Fujimoto T, Tokuda Y. Retroperitoneal panniculitis. BMJ Case Rep. 2015;2015.

230. Tokuda Y. Current Status of Choosing Wisely in Japan. General Medicine. 2015;16(1):3-4.

231. Tokuda Y. Diagnostic Error in Japan: Call for papers! Journal of General and Family Medicine. 2015;16(4):227-228.

232. Tokuda Y. Choosing Wisely International and Japan. General Medicine. 2015;16(2):61-62.

233. Tokuda Y. Lean Health Care: A Core Vision of the Health Care 2035. Journal of General and Family Medicine. 2015;16(3):129-130.

234. Watanabe Y, Abe T, Tokuda Y. Another pharyngitis mimic: intraoral haematoma of the posterior wall of the pharynx in a patient on warfarin and drug-drug interaction. BMJ Case Rep. 2015;2015.

235. Watanuki S, Honda H, Minemura N, Manesh RS, Raoult D, Tokuda Y. Sutton’s Law: Keep Going Where The Money Is. Journal of general internal medicine. 2015;30(11):1711-1715.

236. Watari T, Shimizu T, Tokuda Y. Crusted Scabies Initially Considered as Bullous Pemphigoid and Exacerbated by Steroid Use. Journal of General and Family Medicine. 2015;16(3):208-209.

237. Watari T, Tokuda Y. Bleeding from a gut lesion as a cause of seizure. BMJ case reports. 2015;2015:bcr2014205619.

238. Watari T, Tokuda Y. Drug-induced hemichorea. BMJ case reports. 2015;2015:bcr2014208872.

239. Hamano J, Tokuda Y. Changes in vital signs as predictors of bacterial infection in home care: a multi-center prospective cohort study. Postgraduate Medicine. 2016:1-5.

240. Hamano J, Tokuda Y, Kawagoe S, Shinjo T, Shirayama H, Ozawa T, Shishido H, Otomo S, Nagayama J, Baba M. Adding items that assess changes in activities of daily living does not improve the predictive accuracy of the Palliative Prognostic Index. Palliative medicine. 2016:0269216316650788.

241. Honda H, Horiuchi M, Higuchi M, Murakami S, Tagashira Y, Tokuda Y. Effectiveness of Carbapenems and Piperacillin/Tazobactam Antimicrobial Stewardship at a Japanese Tertiary Care Center: The Impact on Changes in the Use of Other Antipseudomonal Agents. Paper presented at: Open Forum Infectious Diseases, 2016.

242. Kamata K, Abe T, Kabayashi H, Tokuda Y. Chocolate Colored Urine. Journal of General and Family Medicine. 2016;17(3):252-253.

243. Kurihara M, Tokuda Y. Jolt accentuation of neck pain: a novel physical finding for crowned dens syndrome. BMJ Case Reports. 2016;2016:bcr2016217128.

244. Mizuno A, Shimizu T, Tokuda Y. MIMIc STEMI; Typical ECG of Takotsubo-cardiomyopathy. Journal of General and Family Medicine. 2016;17(1):105-108.

245. Narita M, Tokuda Y, Barnett P. Professionalism of physicians at a major teaching hospital during the Fukushima nuclear disaster. QJM. 2016;109(7):447-448.

246. Nishiguchi S, Branch J, Kitagawa I, Tokuda Y. Individuals Aged 75 and Older Dying at Night: A Retrospective Cohort Study in a Japanese Acute Care Hospital. Journal of the American Geriatrics Society. 2016;64(7):1516-1518.

247. Nishiguchi S, Inada H, Kitagawa I, Tokuda Y. Factors associated with a delayed diagnosis of pulmonary embolism. Diagnosis. 2016;3(1):37-41.

248. Numata K, Suzuki M, Mashiko R, Tokuda Y. Lethal bilateral cerebral infarction caused by Moyamoya disease. QJM. 2016;109(7):501-501.

249. Sakihama T, Tokuda Y. Use of peripheral parenteral nutrition solutions as a risk factor for Bacillus cereus peripheral venous catheter-associated bloodstream infection at a Japanese tertiary care hospital: A case-control study. Japanese journal of infectious diseases. 2016;69(6):531-533.

250. Sato S, Terane A, Nishiguchi S, Branch J, Kawada J, Kitagawa I, Tokuda Y. Intractable Hiccups and Nausea as a Principal Symptom of Neuromyelitis Optica in a Patient with a Prior History of Miller-Fisher Syndrome. Journal of General and Family Medicine. 2016;17(1):99-104.

251. Sawagashira R, Watari T, Tokuda Y. Rapidly Progressive Tetraparesis with Ossification of the Posterior Longitudinal Ligament (OPLL). Journal of General and Family Medicine. 2016;17(2):158-159.

252. Takada S, Nishimura M, Yamaguchi K, Tokuda Y. Hot dog lymphadenopathy of prostate cancer. BMJ Case Reports. 2016;2016:bcr2016217160.

253. Tokuda Y. Ethical Basis of Recognizing Generalist Physicians in Japan. Journal of General and Family Medicine. 2016;17(3):189-190.

254. Tokuda Y. Polypharmacy, Inappropriate Prescribing and Adverse Drug Events in Japan. Journal of General and Family Medicine. 2016;17(1):3-4.

255. Tokuda Y, Aoki M. Action against Antimicrobial Resistance: Role of Generalist Physicians in Japan. Journal of General and Family Medicine. 2016;17(4):270-271.

256. Tokuda Y, Birrer RB. Early Recognition of Sepsis. Anaesthesia, Critical Care and Pain Management. 2016;1(1):1.

257. Torigoe K, Tokuda Y. Potential Usefulness of Diagnostic Reminder as Web-based Clinical Decision Support System. Journal of Health Science. 2016;4:297-303.

258. Watari T, Sato S, Uojima H, Tokuda Y. Successful Combination Therapy Including Plasma Exchange for Severe Toxic Epidermal Necrolysis. Journal of General and Family Medicine. 2016;17(3):232-237.

259. Birrer RB, Tokuda Y. Medicalization: A historical perspective. Journal of General and Family Medicine. 2017;18(2):48-51.

260. Fujikawa T, Tokuda Y. Trousseau syndrome. BMJ Case Rep. 2017;2017.

261. Hamano J, Tokuda Y. Authors reply: delta HR/BT as a possible predictor of severity or mortality, not a predictor of bacterial infection. Postgrad Med. 2017;129(7):779.

262. Hamano J, Tokuda Y. Changes in vital signs as predictors of bacterial infection in home care: a multi-center prospective cohort study. Postgrad Med. 2017;129(2):283-287.

263. Hamano J, Tokuda Y, Kawagoe S, Shinjo T, Shirayama H, Ozawa T, Shishido H, Otomo S, Nagayama J, Baba M, Tei Y, Hiramoto S, Suga A, Hisanaga T, Ishihara T, Iwashita T, Kaneishi K, Kuriyama T, Maeda T, Morita T. Adding items that assess changes in activities of daily living does not improve the predictive accuracy of the Palliative Prognostic Index. Palliat Med. 2017;31(3):258-266.

264. Hanai S, Kinjo K, Uezato M, Tokuda Y. A disclosed diagnosis for 24 year's unknown illness. BMJ Case Rep. 2017;2017.

265. Hanai S, Shinzato T, Inazu D, Tokuda Y. Hypercalcaemia caused by active pulmonary tuberculosis in an elderly person without fever or pulmonary symptoms. BMJ Case Rep. 2017;2017.

266. Honda H, Ohmagari N, Tokuda Y, Mattar C, Warren DK. Antimicrobial Stewardship in Inpatient Settings in the Asia Pacific Region: A Systematic Review and Meta-analysis. Clin Infect Dis. 2017;64(suppl_2):S119-S126.

267. Kamata K, Birrer RB, Tokuda Y. Travel medicine: Part 1–The basics. Journal of General and Family Medicine. 2017;18(2):52-55.

268. Kamata K, Birrer RB, Tokuda Y. Travel medicine: Part 2—Special situations. Journal of General and Family Medicine. 2017.

269. Katayama K, Tokuda Y. Severe Hypophosphatemia: Its Prevalence and Predictors Associated with In-hospital Mortality. Journal of General and Emergency Medicine. 2017;4:15-98.

270. Katayama K, Tokuda Y. Mineralocorticoid responsive hyponatremia of the elderly: A systematic review. Medicine (Baltimore). 2017;96(27):e7154.

271. Krein SL, Greene MT, Apisarnthanarak A, Sakamoto F, Tokuda Y, Sakihama T, Fowler KE, Ratz D, Saint S. Infection Prevention Practices in Japan, Thailand, and the United States: Results From National Surveys. Clin Infect Dis. 2017;64(suppl_2):S105-S111.

272. Kuriyama A, Takada T, Irie H, Sakuraya M, Katayama K, Kawakami D, Iwasaki H, Fowler KE, Tokuda Y, Saint S. Prevalence and Appropriateness of Urinary Catheters in Japanese Intensive Care Units: Results From a Multicenter Point Prevalence Study. Clin Infect Dis. 2017;64(suppl_2):S127-S130.

273. Maruyama I, Tokuda Y. Changing work styles among Japanese healthcare professionals. J Gen Fam Med. 2017;18(4):152.

274. Mizuno A, Iguchi H, Sawada Y, Hurley M, Nomura H, Hayashi K, Tokuda Y, Watanabe S, Yoshikawa A. The impact of carperitide usage on the cost of hospitalization and outcome in patients with acute heart failure: High value care vs. low value care campaign in Japan. Int J Cardiol. 2017;241:243-248.

275. Nakanishi T, Goto T, Kobuchi T, Kimura T, Hayashi H, Tokuda Y. The effects of flipped learning for bystander cardiopulmonary resuscitation on undergraduate medical students. Int J Med Educ. 2017;8:430-436.

276. Nemoto T, Tokuda Y, Hirose M, Naitoh Y, Yamasaki Y, Shimizu T, Nishisako H, Kunishima H, Matsuda T. Thoracic Aortic Graft Infection due to Candida Albicans with Multiple Embolism in the Left-side Vessels of the Body. Intern Med. 2017;56(9):1107-1111.

277. Nishizaki Y, Mizuno A, Shinozaki T, Okubo T, Tsugawa Y, Shimizu T, Konishi R, Yamamoto Y, Yanagisawa N, Shiojiri T. Educational environment and the improvement in the General Medicine In‐training Examination score. Journal of General and Family Medicine. 2017.

278. Norisue Y, Tokuda Y, Juarez M, Uchimido R, Fujitani S, Stoeckel DA. Combined cumulative sum (CUSUM) and chronological environmental analysis as a tool to improve the learning environment for linear-probe endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) trainees: a pilot study. BMC Pulm Med. 2017;17(1):32.

279. Numata K, Shimoda K, Shibata Y, Shioya A, Tokuda Y. The Development of Cerebral Venous Thrombosis after Tadalafil Ingestion in a Patient with Antiphospholipid Syndrome. Internal Medicine. 2017;56(10):1235-1237.

280. Sato R, Watari T, Tokuda Y. Fatal case of descending necrotising mediastinitis. BMJ Case Rep. 2017;2017.

281. Shinotsuka M, Tokuda Y. Milk pancreatitis with hypertriglyceridemia and diabetic ketoacidosis. J Gen Fam Med. 2017;18(6):422-424.

282. Sonoda K, Tanaka Y, Tokuda Y. A young man with multiple joint pains and fever: A case with the importance of accurate history taking. Journal of General and Family Medicine. 2017;18(2):79-81.

283. Suzuki T, Tokuda Y, Kobayashi H. The Development of Yellow Nail Syndrome after the Implantation of a Permanent Cardiac Pacemaker. Intern Med. 2017;56(19):2667-2669.

284. Terada N, Hamada Y, Tokuda Y. Streptococcus dysagalactiae pyomyositis. Journal of General and Family Medicine. 2017.

285. Terada N, Tokuda Y. Acute aortic dissection as a cause of shaking chills. Journal of General and Family Medicine. 2017.

286. Tokuda Y. Welcome to the new online renewal of the journal. Journal of General and Family Medicine. 2017;18(1):4-4.

287. Tokuda Y, Aoki M, Machi J. Dr. N. L. Gault, Jr. (1920-2008) and History of Medical Education in South Korea and Okinawa. J Gen Fam Med. 2017;18(3):100-101.

288. Tokuda Y, Barnett PB. Constructing a New US Military Base: A Health Threat to Okinawan People. Environmental Justice. 2017;10(1):23-25.

289. Tokuda Y, Torigoe K, Matsumoto K, Yasuda H. Evaluation of a Web-based Diagnosis Reminder System for Difficult Diagnostic Reasoning. Journal of Health Science. 2017;5:107-109.

290. Watari T, Sekine I, Tokuda Y. Fish hook injury: an easy removal using the string yank technique. BMJ Case Rep. 2017;2017.

291. Watari T, Tokuda Y. Shiitake dermatitis. QJM. 2017.

292. Fujikawa T, Tokuda Y. Ascites from intraperitoneal urine leakage after pelvic radiation. Cleve Clin J Med. 2018;85(3):188-189.

293. Honda H, Murakami S, Tagashira Y, Uenoyama Y, Goto K, Takamatsu A, Hasegawa S, Tokuda Y. Efficacy of a Postprescription Review of Broad-Spectrum Antimicrobial Agents With Feedback: A 4-Year Experience of Antimicrobial Stewardship at a Tertiary Care Center. Open Forum Infect Dis. 2018;5(12):ofy314.

294. Kamata K, Tokuda Y, Gu Y, Ohmagari N, Yanagihara K. Public knowledge and perception about antimicrobials and antimicrobial resistance in Japan: A national questionnaire survey in 2017. PLoS One. 2018;13(11):e0207017.

295. Kishimoto K, Watari T, Tokuda Y. Pseudo-pneumothorax: skin fold is an excellent imitator. BMJ Case Rep. 2018;2018.

296. Moromizato T, Garcia-Larsen V, Soeteman D, Wickner PG, Havens JM, Lund R, Eriguchi R, Tokuda Y, Murata K, Iseki K, Singh AK, Christopher KB. Addressing the gap in clinical research education: Implementation of the Introduction to Clinical Research Training-Japan program. J Gen Fam Med. 2018;19(6):188-190.

297. Nagano H, Kamata K, Tokuda Y. Multiple gout tophi. QJM. 2018;111(6):419-420.

298. Nakamura T, Watari T, Tokuda Y. Over-the-counter drug-induced lung injuries with both diffuse alveolar haemorrhage and diffuse alveolar damage. BMJ Case Rep. 2018;2018.

299. Nishiguchi S, Tomiyama S, Kitagawa I, Tokuda Y. Delayed isolation of smear-positive pulmonary tuberculosis patients in a Japanese acute care hospital. BMC Pulm Med. 2018;18(1):94.

300. Nishizaki Y, Shinozaki T, Kinoshita K, Shimizu T, Tokuda Y. Awareness of Diagnostic Error among Japanese Residents: a Nationwide Study. J Gen Intern Med. 2018;33(4):445-448.

301. Sakaguchi K, Tokuda Y. Left shoulder pain in patients with old myocardial infarction could be a neuropathic pain from spinal epidural haematoma. BMJ Case Rep. 2018;2018.

302. Shimizu T, Nemoto T, Tokuda Y. Effectiveness of a clinical knowledge support system for reducing diagnostic errors in outpatient care in Japan: A retrospective study. Int J Med Inform. 2018;109:1-4.

303. Soshi M, Mizuta T, Tokuda Y. Subclinical cancer diagnosis fallacy. J Gen Fam Med. 2018;19(3):70-71.

304. Soshi M, Mizuta T, Tokuda Y. Overtesting in Japan. J Gen Fam Med. 2018;19(2):42.

305. Soshi M, Tokuda Y. Hidden Curricula, Ethics, and Professionalism. Ann Intern Med. 2018;169(6):425.

306. Soshi M, Tokuda Y. Sexual harassment: The most challenging issue of medical professionalism in Japan. J Gen Fam Med. 2018;19(4):118-120.

307. Takamatsu A, Tagashira Y, Ishii K, Morita Y, Tokuda Y, Honda H. Optimal timing of surgical antimicrobial prophylaxis in laparoscopic surgery: a before-after study. Antimicrob Resist Infect Control. 2018;7:126.

308. Tanaka H, Ueda K, Watanuki S, Watari T, Tokuda Y, Okumura T. Disease vocabulary size as a surrogate marker for physicians' disease knowledge volume. PLoS One. 2018;13(12):e0209551.

309. Tokuda Y. Physical Diagnosis of Cardiac Tamponade. Am J Med. 2018;131(12):e504.

310. Tokuda Y, Soshi M, Okubo T, Nishizaki Y. Postgraduate medical education in Japan: Missed opportunity for learning clinical reasoning. J Gen Fam Med. 2018;19(5):152-153.

311. Watari T, Tokuda Y. Double tongue signs in a case of submandibular space infection. BMJ Case Rep. 2018;2018.

312. Watari T, Tokuda Y. Fever of unknown origin, bilateral sensorineural hearing loss with canal paresis and uveitis with iridocyclitis and episcleritis: a case of Cogan's syndrome. BMJ Case Rep. 2018;2018.

313. Watari T, Tokuda Y. MRI thermal burn injury: an unrecognized consequence of wearing novel, high-tech undergarments. QJM. 2018;111(7):495-496.

314. Watari T, Tokuda Y. Isolated Dissection of the Superior Mesenteric Artery. Intern Med. 2018;57(7):1059.

315. Abe T, Kushimoto S, Tokuda Y, Phillips GS, Rhodes A, Sugiyama T, Komori A, Iriyama H, Ogura H, Fujishima S, Shiraishi A, Saitoh D, Mayumi T, Naito T, Takuma K, Nakada TA, Shiino Y, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Tsuruta R, Hagiwara A, Yamakawa K, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Gando S, group JF. Implementation of earlier antibiotic administration in patients with severe sepsis and septic shock in Japan: a descriptive analysis of a prospective observational study. Crit Care. 2019;23(1):360.

316. Abe T, Tokuda Y, Shiraishi A, Fujishima S, Mayumi T, Sugiyama T, Deshpande GA, Shiino Y, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Hagiwara A, Yamakawa K, Takeyama N, Gando S, Group JSS. In-hospital mortality associated with the misdiagnosis or unidentified site of infection at admission. Crit Care. 2019;23(1):202.

317. Hamano J, Tokuda Y. Prevalence of obstructive sleep apnea in primary care patients with hypertension. J Gen Fam Med. 2019;20(1):39-42.

318. Kuriyama A, Fowler KE, Meddings J, Irie H, Kawakami D, Iwasaki H, Sakuraya M, Katayama K, Tokuda Y, Saint S. Reducing unnecessary urethral catheter use in Japanese intensive care units: A multicenter interventional study. Infect Control Hosp Epidemiol. 2019;40(11):1272-1274.

319. Murakami S, Hiroi J, Tokuda Y, Casabar E, Honda H. Methods of estimating vancomycin use in an inpatient setting: days of therapy versus therapeutic drug monitoring–based exposure days. Infection Control & Hospital Epidemiology. 2019;40(3):375-379.

320. Norisue Y, Santanda T, Homma Y, Tomita S, Saito S, Kataoka J, Fujimoto Y, Nabeshima T, Tokuda Y, Fujitani S. Ultrasonographic Assessment of Passive Cephalic Excursion of Diaphragm During Cough Expiration Predicts Cough Peak Flow in Healthy Adults. Respir Care. 2019;64(11):1371-1376.

321. Sakamoto F, Asano K, Sakihama T, Saint S, Greene MT, Patel P, Ratz D, Tokuda Y. Changes in health care-associated infection prevention practices in Japan: Results from 2 national surveys. Am J Infect Control. 2019;47(1):65-68.

322. Sonoda K, Kato R, Kojima H, Tokuda Y. Urinary tract bleeding from a urethral caruncle mimicking genital tract bleeding. BMJ Case Rep. 2019;12(2).

323. Tokuda Y. Discriminations in medicine and public health: Moral challenges for modern Japanese physicians. J Gen Fam Med. 2019;20(2):46.

324. Tokuda Y. A thankful recommendation from the Organization for Economic Cooperation and Development to health policy of Japan. J Gen Fam Med. 2019;20(4):128.

325. Tokuda Y, Barnett PB. Abolishing the entire system of nuclear weapons: An issue of quality control and public safety. J Gen Fam Med. 2019;20(6):220.

326. Watari T, Hirose M, Midlov P, Tokuda Y, Kanda H, Okayama M, Yoshikawa H, Onigata K, Igawa M. Primary care doctor fostering and clinical research training in Sweden: Implications for Japan. J Gen Fam Med. 2019;20(1):4-8.

327. Watari T, Tokuda Y. Anterior cutaneous nerve entrapment syndrome. BMJ Case Rep. 2019;12(12).

328. Abe T, Ikeda T, Tokuda Y, Ito J, Suzuki Y, Narahara C, Iriyama H, Sato K. A patient infected with SARS-CoV-2 over 100 days. QJM: An International Journal of Medicine. 2020;114(1):47–49.

329. Honda H, Murakami S, Tokuda Y, Tagashira Y, Takamatsu A. Critical national shortage of cefazolin in Japan: management strategies. Clinical Infectious Diseases. 2020;71(7):1783-1789.

330. Ishimaru N, Suzuki S, Shimokawa T, Akashi Y, Takeuchi Y, Ueda A, Kinami S, Suzuki H, Tokuda Y, Maeno T. Heckerling’s criteria to distinguish community-acquired pneumonia in a Japanese primary care setting: observational Study. Asia Pacific Family Medicine. 2020;18(2).

331. Kamata K, Abe T, Aoki M, Deshpande G, Saitoh D, Tokuda Y. Dynamic vital signs may predict in-hospital mortality in elderly trauma patients. Medicine. 2020;99(25).

332. Kamata K, Kuriyama A, Chopra V, Saint S, Houchens N, Petrilli CM, Kuhn L, Snyder A, Ishimaru N, Takahashi H, Tokuda Y. Patient Preferences for Physician Attire: A Multicenter Study in Japan. Journal of hospital medicine. 2020;15(4):204-210.

333. Kamata K, Ohmagari N, Tokuda Y. Universal public use of surgical mask and respiratory viral infection. Journal of General and Family Medicine. 2020;21(3):35-36.

334. Kono K, Watari T, Tokuda Y. Assessment of Academic Achievement of Female Physicians in Japan. JAMA Network Open. 2020;3(7):e209957-e209957.

335. Kuniya T, Nakama Y, Tokuda Y. Demand and supply of invasive and noninvasive ventilators at the peak of the COVID‐19 outbreak in Okinawa. Journal of General and Family Medicine. 2020;21(4):98-101.

336. Kurihara M, Tokuda Y. Learning important clinical skills during junior residency in Japan: A Case of Gram Stain. Journal of General and Family Medicine. 2020;21(3):33-34.

337. Mizuno A, Miyashita M, Kohno T, Tokuda Y, Fujimoto S, Nakamura M, Takayama M, Niwa K, Fukuda T, Ishimatsu S. Quality indicators of palliative care for acute cardiovascular diseases. Journal of Cardiology. 2020;76(2):177-183.

338. Nishiguchi S, Nishino K, Kitagawa I, Tokuda Y. Inappropriate use of antibiotics in primary care for patients with infective endocarditis. Journal of Infection and Chemotherapy. 2020;26(6):640-642.

339. Nishiguchi S, Nishino K, Kitagawa I, Tokuda Y. Factors associated with delayed diagnosis of infective endocarditis: A retrospective cohort study in a teaching hospital in Japan. Medicine. 2020;99(30):e21418.

340. Nishizaki Y, Shimizu T, Shinozaki T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Impact of general medicine rotation training on the in-training examination scores of 11, 244 Japanese resident physicians: a Nationwide multi-center cross-sectional study. BMC Medical Education. 2020;20(1):1-10.

341. Nishizaki Y, Ueda R, Shinozaki T, Tokuda Y. Hospital characteristics preferred by medical students for their residency programs: A nationwide matching data analysis. Journal of General and Family Medicine. 2020;21(6):242-247.

342. Sakihama T, Kayauchi N, Kamiya T, Saint S, Fowler KE, Ratz D, Sato Y, Iuchi R, Honda H, Tokuda Y. Assessing sustainability of hand hygiene adherence 5 years after a contest-based intervention in 3 Japanese hospitals. Am J Infect Control. 2020;48(1):77-81.

343. Shiga T, Nakashima Y, Norisue Y, Ikegami T, Uechi T, Otaki Y, Nakano H, Ryu K, Wakai S, Funakoshi H, Tokuda Y. Comparison of professionalism between emergency medicine resident physicians and faculty physicians: A multicenter cross-sectional study. PloS one. 2020;15(3):e0230186.

344. Shimizu K, Kondo T, Tokuda Y, Shibuya K. An open letter to Japan's new Prime Minister. Lancet. 2020;396(10259):e57.

345. Suzuki S, Ishimaru N, Akashi Y, Takeuchi Y, Ueda A, Ushiki A, Kinami S, Suzuki H, Tokuda Y, Maeno T. Physicians' prediction for the assessment of atypical pathogens in respiratory tract infections. Journal of General and Family Medicine. 2020;21(6):226-234.

346. Tan BKJ, Man REK, Gan ATL, Fenwick EK, Varadaraj V, Swenor BK, Gupta P, Wong TY, Trevisan C, Lorenzo-López L, Millán-Calenti J, Schwanke C, Liljas A, Al SS, Tokuda Y, Lamoureux E. Is Sensory Loss an Understudied Risk Factor for Frailty? A Systematic Review and Meta-analysis. The Journals of Gerontology: Series A. 2020;75(12):2461-2470.

347. Tokuda Y. Japan's lack of accountability for conducting research on deadly pathogens. Journal of General and Family Medicine. 2020;21(1):1-1.

348. Tokuda Y, Matayoshi T, Nakama Y, Kurihara M, Suzuki T, Kitahara Y, Kitai Y, Nakamura T, Itokazu D, Miyazato T. Cardiac auscultation skills among junior doctors: effects of sound simulation lesson. International Journal of Medical Education. 2020;11:107.

349. Tokuda Y, Sakihama T, Aoki M, Taniguchi K, Deshpande GA, Suzuki S, Uda S, Kurokawa K. Independent investigation may be more reliable in the event with political nature. Journal of General and Family Medicine. 2020.

350. Tokuda Y, Sakihama T, Aoki M, Taniguchi K, Deshpande GA, Suzuki S, Uda S, Kurokawa K. COVID‐19 outbreak on the diamond princess cruise ship in February 2020. Journal of General and Family Medicine. 2020;21(4):95.

351. Tokuda Y, Shibuya K, Kondo T. Saliva sampling as the gold standard method of RT-PCR test for transmissibility among pre-symptomatic or asymptomatic people. JAMA internal medicine. 2020;180(11):1447-1452.

352. Watari T, Tokuda Y, Mitsuhashi S, Otuki K, Kono K, Nagai N, Onigata K, Kanda H. Factors and impact of physicians’ diagnostic errors in malpractice claims in Japan. PloS one. 2020;15(8):e0237145.

353. Watari T, Tokuda Y, Owada M, Onigata K. The utility of virtual patient simulations for clinical reasoning education. International journal of environmental research and public health. 2020;17(15):5325.

354. Abe T, Tokuda Y, Iriyama H, Iwagami M, Komori A, Sugiyama T, Tamiya N. Surgical mask use by healthcare personnel to prevent COVID‐19 spread in a long‐term care facility. Journal of general and family medicine. 2021;22(2):100-103.

355. Greene MT, Krein SL, Huis A, Hulscher M, Sax H, Sakamoto F, Sakihama T, Tokuda Y, Fowler KE, Saint S. Infection prevention practices in the United States, the Netherlands, Switzerland, and Japan: Results from national surveys. Infection Control & Hospital Epidemiology. 2021:1-9.

356. Ishimaru N, Suzuki S, Shimokawa T, Akashi Y, Takeuchi Y, Ueda A, Kinami S, Ohnishi H, Suzuki H, Tokuda Y. Predicting Mycoplasma pneumoniae and Chlamydophila pneumoniae in community-acquired pneumonia (CAP) pneumonia: epidemiological study of respiratory tract infection using multiplex PCR assays. Internal and Emergency Medicine. 2021:1-9.

357. Katayama K, Nishizaki Y, Shinozaki T, Saitoh Y, Yano T, Aoki T, Noguchi M, Tokuda Y. The impact of autopsy participation on clinical residency. Journal of General and Family Medicine. 2021.

358. Kitazawa K, Tokuda Y, Koizumi S. Health-care-seeking behaviours of the Japanese lay public during the COVID-19 pandemic: a cross-sectional study. Journal of Primary Health Care. 2021;13(4):351-358.

359. Kurihara M, Kinjo S, Tokuda Y. Rare presentation of Graves’ disease with myalgia: A case report. Clinical Case Reports. 2021;9(10):e04629.

360. Kurihara M, Nagao Y, Tokuda Y. Incident reporting among physicians‐in‐training in Japan: A national survey. Journal of General and Family Medicine. 2021.

361. Kurihara M, Nasu M, Itokazu D, Tokuda Y. Kushiyaki‐related Streptococcus suis meningitis with ventriculitis: A case report. Clinical Case Reports. 2021;9(5):e04108.

362. Kurihara M, Tokuda Y. Ceftriaxone‐associated pseudolithiasis. Journal of General and Family Medicine. 2021.

363. Nagasaki K, Nishizaki Y, Nojima M, Shimizu T, Konishi R, Okubo T, Yamamoto Y, Morishima R, Kobayashi H, Tokuda Y. Validation of the General Medicine in-Training Examination Using the Professional and Linguistic Assessments Board Examination Among Postgraduate Residents in Japan. International Journal of General Medicine. 2021;14:6487.

364. Nagasaki K, Nishizaki Y, Shinozaki T, Kobayashi H, Tokuda Y. Association between resident duty hours and self-study time among postgraduate medical residents in Japan. JAMA network open. 2021;4(3):e210782-e210782.

365. Nishizaki Y, Nozawa K, Shinozaki T, Shimizu T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Difference in the general medicine in-training examination score between community-based hospitals and university hospitals: a cross-sectional study based on 15,188 Japanese resident physicians. BMC medical education. 2021;21(1):1-9.

366. Norisue Y, Deshpande GA, Kamada M, Nabeshima T, Tokuda Y, Goto T, Ishizuka N, Hara Y, Nakata R, Makino J. Allocation of mechanical ventilators during a pandemic: a mixed-methods study of perceptions among Japanese health care workers and the general public. Chest. 2021.

367. Norisue Y, Santanda T, Nabeshima T, Tomita S, Saito S, Kataoka J, Fujimoto Y, Tokuda Y, Homma Y, Fujitani S. Association of Diaphragm Movement During Cough, as Assessed by Ultrasonography, With Extubation Outcome. Respiratory Care. 2021;66(11):1713-1719.

368. Shimizu K, Kondo K, Osugi Y, Negita M, Mase H, Kondo T, Aoki M, Taniguchi K, Shibuya K, Tokuda Y. Early COVID‐19 testing is critical to end the pandemic. Journal of general and family medicine. 2021;22(2):67.

369. Shimizu K, Kuniya T, Tokuda Y. Modeling population‐wide testing of SARS‐CoV‐2 for containing COVID‐19 pandemic in Okinawa, Japan. Journal of General and Family Medicine. 2021.

370. Shimizu K, Tokuda Y, Shibuya K. Japan should aim to eliminate covid-19. British Medical Journal 2021;372:294.

371. Sonoda K, Kolb NR, Tokuda Y. Pulmonary sequestration in an adult patient without prior pulmonary conditions. BMJ case reports. 2021;14(11).

372. Suzuki T, Itokazu D, Tokuda Y. External validation for sensitivity of the Ottawa subarachnoid hemorrhage rule in a Japanese tertiary teaching hospital. Scientific Reports. 2021;11(1):1-7.

373. Suzuki T, Kataoka K, Nishizaki Y, Kono S, Tokuda Y. Discrepancy between national medical licencing examination content and disease conditions encountered in postgraduate clinical training in Japan. Postgraduate medical journal. 2021.

374. Tokuda Y. Japan should learn useful ideas from successful countries during the pandemic: a case of New Zealand. Journal of General and Family Medicine. 2021;22(3):117-117.

375. Tokuda Y. Biomedical science and clinical reasoning for choosing wisely top five list. Journal of General and Family Medicine. 2021;22(4):169.

376. Tokuda Y. Comment on "Interpreting SARS-CoV-2 test results": RT-PCR test specificity is almost 100%. JAMA. 2021;326(15):1528-1529.

377. Tokuda Y, Kuniya T. Prediction of COVID‐19 cases during Tokyo's Olympic and Paralympic Games. Journal of General and Family Medicine. 2021.

378. Tokuda Y, Kuniya T, Shibuya K. Potential impact of alternative vaccination strategies on COVID‐19 cases, hospitalization, and mortality in Japan during 2021–2022. Journal of General and Family Medicine. 2021;22(6):311.

379. Tokuda Y, Sakihama T, Aoki M, Taniguchi K, Deshpande GA, Suzuki S, Uda S, Kurokawa K. Authors’ reply: Independent investigation may be more reliable in the event with political nature. Journal of General and Family Medicine. 2021;22(2):115-115.

380. Tokuda Y, Shibuya K, Oguro K. Priority of SARS‐CoV‐2 test, trace, and isolation in Japan. Journal of General and Family Medicine. 2021;22(1):1.

381. Hamada S, Tokuda Y, Honda H, Watari T, Suzuki T, Moromizato T, Narita M, Taniguchi K, Shibuya K. Prevalence and characteristics of antibiotic prescription for acute COVID-19 patients in Japan. Scientific Reports. 2022;12(1):1-6.

382. Houchens N, Saint S, Petrilli C, Kuhn L, Ratz D, Lott LD, Zollinger M, Sax H, Kamata K, Kuriyama A, Tokuda Y, Fumagalli C, Virgili G, Fumagalli S, Chopra V. International patient preferences for physician attire: results from cross-sectional studies in four countries across three continents. BMJ Open. 2022;12(10):e061092.

383. Joishy SK, Sadohara M, Kurihara M, Tokuda Y. Complexity of the Diagnosis of COVID-19 in the Context of Pandemicity: Need for Excellence in Diagnostic Acumen. Korean J Fam Med. 2022;43(1):16-26.

384. Katayama K, Meddings J, Saint S, Fowler KE, Ratz D, Tagashira Y, Kawamura Y, Fujikawa T, Nishiguchi S, Kayauchi N, Takagaki N, Tokuda Y, Kuriyama A. Prevalence and appropriateness of indwelling urinary catheters in Japanese hospital wards: a multicenter point prevalence study. BMC Infect Dis. 2022;22(1):175.

385. Kato M, Sakihama T, Kinjo Y, Itokazu D, Tokuda Y. Effect of Climate on COVID-19 Incidence: A Cross-Sectional Study in Japan. Korean J Fam Med. 2022;43(1):37-41.

386. Kuniya T, Tokuda Y, Nakamura H, Moromizato T, Shibuya K. Estimating COVID‐19 herd immunity in Japan at the beginning of the seventh wave: Transitioning from a pandemic to an endemic. Journal of General and Family Medicine. 2022;23(5):295.

387. Kurihara M, Kamata K, Nakahara S, Kitazawa K, Koizumi S, Tokuda Y. Healthcare use and RT-PCR testing during the first wave of the COVID-19 pandemic in Japan. J Gen Fam Med. 2022;23(1):3-8.

388. Kurihara M, Kamata K, Tokuda Y. Impact of the hospitalist system on inpatient mortality and length of hospital stay in a teaching hospital in Japan: a retrospective observational study. BMJ Open. 2022;12(4):e054246.

389. Kurihara M, Watari T, Rohde JM, Gupta A, Tokuda Y, Nagao Y. Nationwide survey on Japanese residents’ experience with and barriers to incident reporting. Plos one. 2022;17(12):e0278615.

390. Miyawaki A, Ikesu R, Tokuda Y, Goto R, Kobayashi Y, Sano K, Tsugawa Y. Prevalence and changes of low-value care at acute care hospitals: a multicentre observational study in Japan. BMJ open. 2022;12(9):e063171.

391. Nagasaki K, Nishizaki Y, Shinozaki T, Kobayashi H, Shimizu T, Okubo T, Yamamoto Y, Konishi R, Tokuda Y. Impact of the resident duty hours on in-training examination score: A nationwide study in Japan. Medical Teacher. 2022;44(4):433-440.

392. Nagasaki K, Nishizaki Y, Shinozaki T, Shimizu T, Yamamoto Y, Shikino K, Fukui S, Nishiguchi S, Kurihara M, Kataoka K, Tokuda Y, Kobayashi H. Association between mental health and duty hours of postgraduate residents in Japan: a nationwide cross-sectional study. Sci Rep. 2022;12(1):10626.

393. Nishiguchi S, Sugaya N, Saigusa Y, Mayama M, Moromizato T, Inamori M, Tokuda Y, Watari T. Effects of Electrocardiographic Monitoring Education on Nurses’ Confidence and Psychological Stress: An Online Cross-Sectional Survey in Japan. International journal of environmental research and public health. 2022;19(8):4742.

394. Patel PK, Satoh N, Narita M, Cho Y, Oshiro Y, Suzuki T, Fowler KE, Greene MT, Tokuda Y, Kaye KS. Inpatient antibiotic prescribing patterns using the World Health Organization (WHO) Access Watch and Reserve (AWaRe) classification in Okinawa, Japan: A point-prevalence survey. Antimicrobial Stewardship & Healthcare Epidemiology. 2022;2(1):e155.

395. Shimizu K, Shibuya K, Tokuda Y. COVID‐19 infodemic about nucleic acid amplification tests in Japan. Journal of General and Family Medicine. 2022;23(1):1.

396. Tokuda Y, Sakihama T. Targeted mass testing and phylogenetic analysis is effective for preventing community transmission of SARS-CoV-2 beta variant. Lancet Reg Health West Pac. 2022;24:100499.

397. Tokuda YK, Y. ABC risks for public health by introducing foreign military bases. Postgraduate Medical Journal. 2022.

398. Watari T, Nakano Y, Gupta A, Kakehi M, Tokonami A, Tokuda Y. Research Trends and Impact Factor on PubMed Among General Medicine Physicians in Japan: A Cross-Sectional Bibliometric Analysis. International Journal of General Medicine. 2022;15:7277-7285.

399. Watari T, Tokuda Y. Role of Japan's general physicians in healthcare quality improvement and patient safety. J Gen Fam Med. 2022;23(3):137-139.

400. Watari T, Tokuda Y. Japan: reform leadership in clinical medicine. Nature. 2022;611(7934):33-33.

401. Watari T, Tokuda Y, Amano Y, Onigata K, Kanda H. Cognitive Bias and Diagnostic Errors among Physicians in Japan: A Self-Reflection Survey. International journal of environmental research and public health. 2022;19(8):4645.

402. Watari T, Tokuda Y, Taniguchi K, Shibuya K. Incidence of and Ivermectin Prescription Trends for COVID-19 in Japan. Journal of General Internal Medicine. 2022:1-3.

403. Fukui S, Shikino K, Nishizaki Y, Shimizu T, Yamamoto Y, Kobayashi H, Tokuda Y. Association between regional quota program in medical schools and practical clinical competency based on General Medicine In-Training Examination score: a nationwide cross-sectional study of resident physicians in Japan. Postgraduate Medical Journal. 2023:qgad059.

404. Hamada S, Moromizato T, Narita M, Taniguchi K, Shibuya K, Tokuda Y. Association between hospital internal medicine physician workforce and patient admissions during the COVID-19 pandemic in Japan. BMC Health Services Research. 2023;23(1):1-7.

405. Hamada S, Suzuki T, Tokuda Y, Taniguchi K, Shibuya K. Comparing clinical outcomes of ARB and ACEi in patients hospitalized for acute COVID-19. Scientific Reports. 2023;13(1):11810.

406. Honda H, Takamatsu A, Miwa T, Tabuchi T, Taniguchi K, Shibuya K, Tokuda Y. Prolonged symptoms after COVID-19 in Japan: A nationwide survey of the symptoms and their impact on patients’ quality of life. The American Journal of Medicine. 2023.

407. Isono H, Kuno H, Hozumi T, Emoto K, Nishiguchi S, Sakai M, Ito M, Kitamura K, Hirose K, Hiraoka E, Ishimaru N, Kobayashi H, Tokuda Y. Crowned dens syndrome: A case series of 72 patients at eight teaching hospitals in Japan. Journal of General and Family Medicine. 2023;24(3):171-177.

408. Kamata K, Honda H, Tokuda Y, Takamatsu A, Taniguchi K, Shibuya K, Tabuchi T. Post-COVID health-related quality of life and somatic symptoms: A national survey in Japan. The American journal of the medical sciences. 2023.

409. Miyagami T, Watari T, Nishizaki Y, Shimizu T, Tokuda Y. Association of diagnostic error education and recognition frequency among Japanese medical students: a nationwide cross-sectional study. Diagnosis. 2023(0).

410. Moromizato T, Sakaniwa R, Tokuda Y, Taniguchi K, Shibuya K. Intravenous methylprednisolone pulse therapy and the risk of in-hospital mortality among acute COVID-19 patients: Nationwide clinical cohort study. Critical Care. 2023;27(1):1-11.

411. Nagasaki K, Nishizaki Y, Hachisuka C, Shinozaki T, Shimizu T, Yamamoto Y, Shikino K, Fukui S, Nishiguchi S, Katayama K. Impact of duty hours on competency‐related knowledge acquisition among community hospital residents. Journal of General and Family Medicine. 2023;24(2):87-93.

412. Nagasaki K, Nishizaki Y, Shinozaki T, Shimizu T, Yamamoto Y, Shikino K, Fukui S, Nishiguchi S, Kurihara M, Katayama K, Kobayashi H, Tokuda Y. Association between prolonged weekly duty hours and self-study time among residents: a cross-sectional study. Postgraduate Medical Journal. 2023.

413. Nishizaki Y, Nagasaki K, Shikino K, Kurihara M, Shinozaki T, Kataoka K, Shimizu T, Yamamoto Y, Fukui S, Nishiguchi S, Katayama K, Kobayashi H, Tokuda Y. Relationship between COVID-19 care and burnout among postgraduate clinical residents in Japan: a nationwide cross-sectional study. BMJ Open. 2023;13(1):e066348.

414. Sakaguchi K, Watari T, Tokuda Y. Evidence‐based prescription of corticosteroids for COVID‐19 patients: A comparison between general medicine and other specialty in Japan. Journal of General and Family Medicine. 2023;24(2):135-138.

415. Tokuda Y, Barnett PB, Sanji S, Takaizumi Y, Tomono M, Tokuda H, Taniguchi K, Shibuya K. Serious mental illness and in-hospital mortality among hospitalized patients with acute COVID-19: A large-database analysis in Japan. General Hospital Psychiatry. 2023.

416. Tokuda YK, S. Rapid Response Re: Reducing the risks of nuclear war. BMJ. 2023;382:1682.

417. Uchida M, Tokuda Y. Myxedema Pleural Effusion and Ascites. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2023;5(1):15-16.

418. Watari T, Houchens N, Nishizaki Y, Kataoka K, Otsuka T, Nakano Y, Sakaguchi K, Shiraishi Y, Katayama K, Kataoka H. Empathy competence and future specialty among medical residents in Japan: a nationwide cross-sectional study. Scientific Reports. 2023;13(1):13742.

419. Watari T, Houchens N, Otsuka T, Endo T, Odagawa S, Nakano Y, Kataoka H, Miwa M, Yamasaki D, Tokuda Y. Differences in empathy levels among physicians based on specialty: a nationwide cross-sectional study. Postgraduate Medical Journal. 2023:qgad084.

420. Watari T, Kurihara M, Nishizaki Y, Tokuda Y, Nagao Y. Safety culture survey among medical residents in Japan: a nationwide cross-sectional study. BMJ Open Quality. 2023;12(4):e002419.

421. Watari T, Nishizaki Y, Houchens N, Kataoka K, Sakaguchi K, Shiraishi Y, Shimizu T, Yamamoto Y, Tokuda Y. Medical resident’s pursuing specialty and differences in clinical proficiency among medical residents in Japan: a nationwide cross-sectional study. BMC Medical Education. 2023;23(1):1-15.

422. Watari T, Takagi S, Sakaguchi K, Nishizaki Y, Shimizu T, Yamamoto Y, Tokuda Y. Performance Comparison of ChatGPT-4 and Japanese Medical Residents in the General Medicine In-Training Examination: Comparison Study. JMIR Medical Education. 2023;9:e52202.

423. Watari T, Tokuda Y. Letter to the editor concerning the article:“Artificial intelligence in clinical pharmacology: A case study and scoping review of large language models and bioweapon potential”. British Journal of Clinical Pharmacology. 2023.

424. Watari T, Tokuda Y, Takahashi H, Taniguchi K, Shibuya K. Analysis of hydroxychloroquine prescriptions for COVID‐19 in Japan. Journal of General and Family Medicine. 2023.

425. Watari T, Tokuda Y, Taniguchi K, Shibuya K. Lessons Learned from Ivermectin. Journal of General Internal Medicine. 2023;38(6):1555-1555.

426. Fukui S, Shimizu T, Nishizaki Y, Shikino K, Yamamoto Y, Kobayashi H, Tokuda Y. The Utility of Wearable Cameras in Developing Examination Questions and Answers on Physical Examinations: Preliminary Study. JMIR Med Educ. 2024;10:e53193.

427. Honda H, Takamatsu A, Miwa T, Tabuchi T, Nakamura H, Taniguchi K, Shibuya K, Tokuda Y. Association of Individual Behaviors With Infection Prevention Measures and COVID-19 Development: A Japanese Cross-Sectional Study. Asia Pacific Journal of Public Health. 2024:10105395241245496.

428. Hsu N-C, Tokuda Y. High-dose corticosteroid therapy in COVID-19: the RECOVERY trial. Lancet. 2024;403(10434):1338.

429. Hsu NC, Tsai HB, Hsu CH, Tsai MY, Liao C, Tokuda Y. Frequency of limitations statements in original research articles of United States leading medical journals: A meta-research protocol. PLoS One. 2024;19(11):e0305970.

430. Katagiri A, Tokuda Y, Taniguchi K, Shibuya K, Tabuchi T. Stroke and Ischemic Heart Disease among LGBT Sexual and Gender Minorities in Japan. Journal of Public Health Sciences. 2024;3(03):159-172.

431. Kataoka K, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Nojima M, Nagasaki K, Fukui S, Nishiguchi S, Katayama K, Kurihara M, Ueda R, Kobayashi H, Tokuda Y. Hospital Use of a Web-Based Clinical Knowledge Support System and In-Training Examination Performance Among Postgraduate Resident Physicians in Japan: Nationwide Observational Study. JMIR Med Educ. 2024;10:e52207.

432. Katayama K, Nishizaki Y, Takada T, Kataoka K, Houchens N, Shimizu T, Yamamoto Y, Watari T, Tokuda Y, Ohira Y. The relation between resident mentorship and in-training examination scores: A nation-wide, cross-sectional study in Japan. J Gen Fam Med. 2024;25(5):249-255.

433. Katayama K, Nishizaki Y, Takada T, Kataoka K, Houchens N, Shimizu T, Yamamoto Y, Watari T, Tokuda Y, Ohira Y. The relation between resident mentorship and in-training examination scores: A nation-wide, cross-sectional study in Japan. Journal of General and Family Medicine. 2024;25(5):249-255.

434. Katayama K, Nishizaki Y, Takada T, Kataoka K, Houchens N, Watari T, Tokuda Y, Ohira Y. Association between mentorship and mental health among junior residents: A nationwide cross‐sectional study in Japan. Journal of General and Family Medicine. 2024;25(1):62-70.

435. Katayama K, Suzuki T, Numata K, Adachi-Katayama M, Watari T, Tokuda Y, Patel PK, Ohira Y. Infection is the Most Frequent Disease Category of Autopsy-detected Diagnostic Errors in Japan. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2024;6(2):17-24.

436. Lyu Z, Harada KH, Kimura-Kuroda J, Tokuda Y. Is Japan at low risk for PFAS immunotoxicity?: human biomonitoring study in contaminated areas in Japan. Environmental Health and Preventive Medicine. 2024;29:37-37.

437. Makishi N, Miyazato K, Tokuda Y, Inafuku T. Cancer-associated neuromyelitis optica spectrum disorder: a case report with literature review. Rinsho Shinkeigaku. 2024;64(8):564-571.

438. Miwa T, Honda H, Takamatsu A, Tabuchi T, Taniguchi K, Shibuya K, Tokuda Y. Association between public health measures and the public’s well-being during the pandemic: a nationwide Japanese study. Journal of Public Health. 2024;47(1):e1-e10.

439. Miwa T, Okamoto K, Nishizaki Y, Tokuda Y. Infectious Disease Physician Availability and Postgraduate Antimicrobial Stewardship Education in Japan. JAMA Network Open. 2024;7(3):e244781-e244781.

440. Miwa T, Okamoto K, Nishizaki Y, Tokuda Y. The characteristics of postgraduate antimicrobial stewardship education resources: a nationwide survey in Japan. J Hosp Infect. 2024;154:137-139.

441. Nagasaki K, Kobayashi H, Nishizaki Y, Kurihara M, Watari T, Shimizu T, Yamamoto Y, Shikino K, Fukui S, Nishiguchi S. Association of sleep quality with duty hours, mental health, and medical errors among Japanese postgraduate residents: a cross-sectional study. Scientific Reports. 2024;14(1):1481.

442. Nishiguchi S, Nishizaki Y, Hamaguchi M, Goto A, Inamori M, Shikino K, Shinozaki T, Kataoka K, Shimizu T, Yamamoto Y, Fukui S, Kobayashi H, Tokuda Y. Experience of caring for patients with COVID-19 and educational achievement among Japanese resident physicians: a nationwide survey with general medicine in-training examination. BMC Med Educ. 2024;24(1):1125.

443. Okazaki T, Nabeshima T, Santanda T, Hoshina Y, Kondo Y, Yaegashi Y, Nakazawa T, Tokuda Y, Norisue Y. Association of Relative Dysglycemia With Hospital Mortality in Critically Ill Patients: A Retrospective Study. Critical Care Medicine. 2024:10.1097.

444. Otsuka T, Sakaguchi K, Houchens N, Nakano Y, Endo T, Odagawa S, Yamasaki D, Miwa M, Shiraishi Y, Tokuda Y. Empathy Among Physicians and Nurses in Japan: A Nationwide Cross-sectional Study. Journal of General Internal Medicine. 2024:1-9.

445. Shikino K, Nishizaki Y, Fukui S, Yokokawa D, Yamamoto Y, Kobayashi H, Shimizu T, Tokuda Y. Development of a Clinical Simulation Video to Evaluate Multiple Domains of Clinical Competence: Cross-Sectional Study. JMIR Medical Education. 2024;10(1):e54401.

446. Shikino K, Nishizaki Y, Kataoka K, Fukui S, Yokokawa D, Shimizu T, Yamamoto Y, Nagasaki K, Kobayashi H, Tokuda Y. A novel resident physician examination using clinical simulation video to assess clinical competence in Japan: a cross-sectional study. BMC Med Educ. 2024;24(1):1402.

447. Shikino K, Nishizaki Y, Kataoka K, Nojima M, Shimizu T, Yamamoto Y, Fukui S, Nagasaki K, Yokokawa D, Kobayashi H, Tokuda Y. Association between physicians' maldistribution and core clinical competency of resident physicians: a nationwide cross-sectional study. BMJ Open. 2024;14(10):e083184.

448. Shikino K, Nishizaki Y, Nagasaki K, Kobayashi H, Kataoka K, Shimizu T, Tokuda Y. Residency Program Directors' Perspectives on Overtime Duty Hours and Professional Development Time in Japan. Adv Med Educ Pract. 2024;15:1185-1194.

449. Shikino K, Sekine M, Nishizaki Y, Yamamoto Y, Shimizu T, Fukui S, Nagasaki K, Yokokawa D, Watari T, Kobayashi H. Distribution of internal medicine rotations among resident physicians in Japan: a nationwide, multicenter, cross-sectional study. BMC Medical Education. 2024;24(1):316.

450. Shikino K, Shimizu T, Otsuka Y, Tago M, Takahashi H, Watari T, Sasaki Y, Iizuka G, Tamura H, Nakashima K. Evaluation of ChatGPT-generated differential diagnosis for common diseases with atypical presentation: descriptive research. JMIR Medical Education. 2024;10:e58758.

451. Shizuku T, Osawa M, Kitagawa I, Tokuda Y. Contarini’s Syndrome: Bilateral Pleural Effusions Due to Different Etiologies. Cureus. 2024;16(1).

452. Takamatsu A, Honda H, Miwa T, Tabuchi T, Taniguchi K, Shibuya K, Tokuda Y. Prevalence and trends in persistent symptoms following COVID-19 in Japan: A nationwide cross-sectional survey. Journal of Infection and Chemotherapy. 2024.

453. Tamune H, Fujikawa H, Harada H, Kodama T, Sasaki M, Sone D, Sekine M, Ito M, Kato T, Nishizaki Y, Tokuda Y. Integrating psychiatry into basic clinical skills: A three-year nationwide quantitative assessment of postgraduate training programs. Psychiatry and Clinical Neurosciences Reports. 2024;3(4):e70014.

454. Tokuda Md MPHY. Prevention and Management of Prescription Cascade. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2024;6(3):51-52.

455. Tokuda MDMPHPFY. Resilience in Hospitals in Japan during the COVID-19 Pandemic. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2024;6(2):13-15.

456. Tokuda MDMPHY. Publishing High-Quality Scientific Papers is the Aim of Our Journal. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2024;6(1):0-0.

457. Tokuda MDMPHY. Experience of resident physicians caring for COVID-19 patients in the different hospital groups. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2024;6(5):117-118.

458. Tokuda Y. Resilience in Hospitals in Japan during the COVID-19 Pandemic. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2024;6(2):13-15.

459. Tokuda Y. Publishing High-Quality Scientific Papers is the Aim of Our Journal. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2024;6(1):0-0.

460. Tokuda Y. Medical Accidents Related to Stress from a Workforce Shortage. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2024;6(6):146-147.

461. Tokuda Y, Sonoda K, Tokuda H, Tomono M, Ando S. Usefulness of a Standalone Smartphone App for Weight Management among Middle-Aged People with Overweight/Obesity. Journal of Consumer Health on the Internet. 2024:1-10.

462. Tomono M, Ando S, Kamau-Mitchell C, Ihara S, Isobe A, Kido H, Sanji S, Watanabe T, Tokuda H, Itokazu D. Burnout and Fear of COVID-19 among Medical Students in Japan: Impact of infection history, gender, and social support. Journal of Public Health Sciences. 2024;3(01):26-38.

463. Watari T, Gupta A, Amano Y, Tokuda Y. Japanese Internists' Most Memorable Diagnostic Error Cases: A Self-reflection Survey. Internal Medicine. 2024;63(2):221-229.

464. Watari T, Gupta A, Hayashi M, Mizuno K, Nakano Y, Tokuda Y, Sakaguchi K. Characteristics of Medical School Deans and University Hospital Directors in Japan. JAMA Network Open. 2024;7(1):e2351526-e2351526.

465. Watari T, Mizuno K, Sakaguchi K, Shimada Y, Tanimoto Y, Nakano Y, Kono K, Tokuda Y. Gender Inequality Improvement in Medical School Admissions in Japan. Journal of Women's Health. 2024;33(3):339-344.

466. Watari T, Sheffield V, Nishizaki Y, Tokuda Y. Differences in the resident encounter of disruptive behavior by gender. Medical Teacher. 2024;46(3):423-425.

467. Yokokawa D, Shikino K, Nishizaki Y, Fukui S, Tokuda Y. Evaluation of a Computer-Based Morphological Analysis Method for Free-Text Responses in the General Medicine In-Training Examination: Algorithm Validation Study. JMIR Med Educ. 2024;10:e52068.

468. Fujii Y, Shibata Y, Tokuda Y, Ito Y, Kudo N, Harada KH. Human exposure and toxicity of per-and polyfluoroalkyl substances: Narrative review and perspectives. Chemosphere. 2025;385:144508.

469. Fujikawa H, Tamune H, Nishizaki Y, Nagasaki K, Kobayashi H, Nojima M, Sekine M, Shimizu T, Yamamoto Y, Shikino K, Tokuda Y. Association between residents’ work hours and patient care ownership: a nationwide cross-sectional study in Japan. BMC Medical Education. 2025;25(1):385.

470. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Kobayashi H, Tokuda Y. Hospital Type and Medical Residents' Patient Care Ownership: A Nationwide Cross-Sectional Study in Japan. The Clinical Teacher. 2025;22(4):e70109.

471. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Sekine M, Nagasaki K, Kobayashi H, Tokuda Y. Supervising physicians' perceptions on physician work-hour regulations in Japan: a nationwide cross-sectional study. BMC Med Educ. 2025;25(1):1489.

472. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Tokuda Y. Undergraduate general medicine education in Japan: A nationwide cross-sectional survey of medical trainees' perspectives. J Gen Fam Med. 2025;26(2):148-156.

473. Fujikawa H, Tamune H, Nishizaki Y, Shikino K, Shimizu T, Yamamoto Y, Tokuda Y. Undergraduate general medicine education in Japan: A nationwide cross-sectional survey of medical trainees' perspectives. Journal of General and Family Medicine. 2025;26(2):148-156.

474. Fujikawa H, Tamune H, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Sekine M, Kobayashi H, Tokuda Y. Association of clinical knowledge with patient care ownership among resident physicians: a nationwide cross-sectional study in Japan. BMC Medical Education. 2025;25(1):77.

475. Hsu N-C, Hsu C-H, Liao C, Tokuda Y, group J-U-Tm-r. Variations and trends in major research topics across leading general medical journals, 1966–2022. Critical Public Health. 2025;35(1):2594711.

476. Katagiri A, Tokuda Y, Barnett PB, Taniguchi K, Shibuya K, Tabuchi T. A cross-sectional study on mental health and quality of life among LGBTQ+ individuals in Japan. Journal of Gay & Lesbian Mental Health. 2025;29(3):345-364.

477. Katayama K, Suzuki T, Adachi-Katayama M, Numata K, Honda Y, Nagano H, Hiramatsu Y, Watari T, Tokuda Y, Patel PK, Ohira Y. Two decades of autopsy-detected diagnostic errors in Japan. Diagnosis. 2025;12(3):365-371.

478. Katayama K, Takada T, Nishizaki Y, Nagasaki K, Shimizu T, Yamamoto Y, Watari T, Tokuda Y, Chopra V, Ohira Y. Self-Reported Time-at-Bedside and Its Association with In-Training Examination Scores of Residents in Japan. J Gen Intern Med. 2025;40(8):1768-1775.

479. Katayama K, Takada T, Nishizaki Y, Nagasaki K, Shimizu T, Yamamoto Y, Watari T, Tokuda Y, Chopra V, Ohira Y. Time-at-bedside and competency acquisition: a secondary analysis of GM-ITE domain scores in Japanese resident physicians. BMC Med Educ. 2025;25(1):1537.

480. Makishi N, Tokuda Y. Acyclovir Encephalopathy in HSV Encephalitis Elderly With Normal Renal Function. Case Rep Neurol Med. 2025;2025:3854205.

481. Makishi N, Tokuda Y. A Case of Essential Palatal Tremor with Remarkable Improvement by Shakuyaku-kanzo-to. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2025;7(6):233-235.

482. Mitsushima S, Ohkusa Y, Taniguchi K, Tokuda Y, Shibuya K. Association between positive preadmission screening and COVID-19 community transmission: A retrospective observational study during an emergent novel infectious disease pandemic. New Microbes New Infect. 2025;68:101647.

483. Miyagami T, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Kobayashi H, Naito T, Tokuda Y. A cross sectional study of the relationship between clinical scores and timing of guidance for resident physicians in outpatient settings. Sci Rep. 2025.

484. Miyagami T, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Nojima M, Deshpande G, Naito T, Tokuda Y. Optimal outpatient training for resident physicians’ general medicine in-training examination score: a cross-sectional study. BMC Medical Education. 2025;25(1):49.

485. Miyagami T, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Nojima M, Deshpande GA, Naito T, Tokuda Y. Evaluating the Use of a Note-Taking App by Japanese Resident Physicians: Nationwide Cross-Sectional Study. JMIR Formative Research. 2025;9(1):e55087.

486. Miyagami T, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Nojima M, Deshpande GA, Naito T, Tokuda Y. Evaluating the Use of a Note-Taking App by Japanese Resident Physicians: Nationwide Cross-Sectional Study. JMIR Formative Research. 2025;9(1):e55087.

487. Nagasaki K, Kawase Y, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Watari T, Kobayashi H, Tokuda Y. Gender Differences in Burnout Among Resident Physicians in Japan: A Nationwide Cross-Sectional Study. Academic Medicine. 2025:wvaf096.

488. Nagasaki K, Nishizaki Y, Shimizu T, Yamamoto Y, Shikino K, Kataoka K, Kobayashi H, Tokuda Y. Educational environment changes toward resident duty hour restrictions in Japan. Scientific Reports. 2025;15(1):16925.

489. Nomura S, Murakami M, Rauniyar SK, Kondo N, Tabuchi T, Sakamoto H, Tokuda Y, Patel N, de Pablo JN, Dieleman JL. Three decades of population health changes in Japan, 1990–2021: a subnational analysis for the Global Burden of Disease Study 2021. The Lancet Public Health. 2025;10(4):e321-e332.

490. Norisue Y, Yamamoto R, Yamakawa H, Hibino M, Nagai T, Fujimoto Y, Kataoka J, Ishii K, Hongo T, Kasugai D, Iwasaki Y, Sakuraya M, Shimizu G, Masuyama T, Fujitani S, Tokuda Y, Ogura T. Incidence of diffuse parenchymal lung disease in patients meeting the Berlin definition of acute respiratory distress syndrome on mechanical ventilation. ERJ Open Res. 2025;11(5).

491. Sakaguchi K, Yamamoto H, Ohira Y, Otsuka T, Yamasaki D, Tokuda Y, Shiraishi Y, Watari T. Parental socioeconomic status and medical specialty choice: a nationwide analysis of Japanese physicians. Postgrad Med J. 2025.

492. Sakaguchi K, Yamamoto H, Ohira Y, Otsuka T, Yamasaki D, Tokuda Y, Shiraishi Y, Watari T. Parental socioeconomic status and medical specialty choice: a nationwide analysis of Japanese physicians. Postgraduate Medical Journal. 2025.

493. Shikino K, Nishizaki Y, Fukui S, Kataoka K, Yokokawa D, Shimizu T, Yamamoto Y, Nagasaki K, Kobayashi H, Tokuda Y. Resident Physician Recognition of Tachypnea in Clinical Simulation Videos in Japan: Cross-Sectional Study. JMIR Med Educ. 2025;11:e72640.

494. Shikino K, Nishizaki Y, Kataoka K, Nagasaki K, Kobayashi H, Shimizu T, Tokuda Y. Optimal Working Hours in the 2024 Physician Work Reform: Insights from a Residency Program Director. Adv Med Educ Pract. 2025;16:1461-1468.

495. Shinzato T, Yonaha T, Tokuda Y, Aoki M. From Organ to Antibiotic: Antibiotic Practice in Outpatient Settings. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2025;7(3):108-113.

496. Suzuki T, Katayama K, Houchens N, Hartley S, Tokuda Y, Watari T. The Future of Hospital Medicine in Japan: Lessons From the United States Hospital Medicine System. International Journal of General Medicine. 2025;18(null):2379-2390.

497. Takamatsu A, Honda H, Miwa T, Tabuchi T, Taniguchi K, Shibuya K, Tokuda Y. Changes in Personal Behaviors During and After the COVID-19 Pandemic: A Nationwide Three-Year Longitudinal Study in Japan. Asia Pac J Public Health. 2025;37(1):108-115.

498. Tokuda Y. Medical Incidents Related to Treatment by Junior Residents. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2025;7(5):167-169.

499. Tokuda Y. Improving Diagnostic Accuracy: Navigating Cognitive Biases through Reflective Practice. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2025;7(3):75.

500. Tokuda Y. War and Medical Ethics: The 1945 Cyanide Incident at Okinawa Army Hospital. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2025;7(4):117-118.

501. Tokuda Y. Reducing Diagnostic Errors: Essential Next Steps to Enhance Quality and Safety. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2025;7(1):1-2.

502. Tokuda Y. Nuclear Deterrence Is a Delusion. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2025;7(6):227-228.

503. Tokuda Y. Generalist Physicians Harnessing the Power of Artificial Intelligence. JOURNAL OF HOSPITAL GENERAL MEDICINE. 2025;7(2):29.

504. Toma K, Ishiki H, Oshiro Y, Shinzato T, Tokuda Y. Necrotizing Fasciitis Due to Group A Streptococcus: A Case of a Deteriorating Biphasic-like Clinical Course over Five Days with a Devastating Outcome. Internal Medicine. 2025;64(5):781-785.

505. Tomono M, Ando S, Harada KH, Lyu Z, Sassa MH, Moromizato T, Nakamura K, Iseki K, Iseki C, Takara C, Nakamura H, Kawamura M, Tokuda H, Harris CM, Tokuda Y. Relationships Between Serum Levels of Per- and Polyfluoroalkyl Substances and Obesity-Related Conditions in Patients of Okinawa, Japan. Exposure and Health. 2025;17(5):1269-1277.

506. Watari T, Sheffield V, Gupta A, Taniguchi K, Tokuda Y, Nishizaki Y. Resident encounters with disruptive workplace behaviours in Japan: findings from a national cross-sectional study. BMJ Open Quality. 2025;14(1):e003093.

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