Yasuharu Tokuda, MD, MPH



Current Affiliated Academic Appointments

  • Health and Global Policy Institute (Fellow)
  • Taiwan Association of Hospital Medicine (International Consultant)
  • Tsukuba University (Adjunct Professor)
  • Ryukyu University (Adjunct Professor)
  • Toho University (Adjunct Professor)
  • St. Marianna University (Adjunct Professor)
  • Dokkyo Medical University (Adjunct Professor)
  • Keio University (Adjunct Faculty)


Peer Review Journals


Scientific Publications (only English-language papers are shown here)

1. Tokuda Y. 1995. Teaching ethics in Japan. Lancet 345:1574

2. Tokuda Y. 1996. Unscientific speculation. Nature 383:381

3. Tokuda Y, Kuwabara K, Miyagi Y. 1997. Tetanus in Okinawa Chubu Hospital. Journal of Okinawa Chubu Hospital 23:30-3

4. Kato J, Toyozato N, Hattori T, Motomura K, Tokuda Y. 1998. Long-term enteral nutrition-associated copper deficiency anemia and leukopenia: A case report and review of the literature. Journal of Okinawa Chubu Hospital 24:20-3

5. Narita M, Sudo S, Tokuda Y. 1998. Syndrome of Passive Hepatic Congestion Mimicking Acute Abdomen in a Patient with Hyperthyroidism: A Case Report and Review of the Literature. Journal of Okinawa Chubu Hospital 24:24-6

6. Tokuda Y. 1998. Low-dose spiral computed tomography for lung-cancer screening. Lancet 352:235-6; author reply 6-7

7. Tokuda Y. 1998. Physicians and biological warfare agents. JAMA 279:273-4

8. Chang D, Koketsu H, Fukunaga T, Miyagi T, Kitamura T, Tamaki K, Arashiro K, Miyagi Y, Tokuda Y. 1999. Pyoderma Gangrenosum Associated with Myelodysplastic Syndrome. Journal of Okinawa Chubu Hospital 25:16-20

9. Tokuda Y, Kato J. 1999. Aspirin and risk of hemorrhagic stroke. JAMA 282:732; author reply -3

10. Higa Y, Hoshino S, Tokuda Y, Tamaki K. 2000. A 22 year-old female with an unexplained bruising tendency: A case report and review of the literature. Journal of Okinawa Chubu Hospital 26:14-7

11. Kato J, Tokuda Y. 2000. Management and outcome of symptomatic hyponatremia in emergency department. In Critical Care, p. 176

12. Nakazato N, Kubota S, Takada S, Kinjo S, Tokuda Y. 2000. Polymyalgia rheumatica: Three cases with atypical presentation. Journal of Okinawa Chubu Hospital 26:11-3

13. Nakazato N, Zukeran H, Arata H, Inadome S, Tokuda Y. 2000. Severe Hypoxemia associated with Neuroleptic Malignant Syndrome. Journal of Okinawa Chubu Hospital 26:30-3

14. Nishitarumizu K, Tokuda Y, Uehara H, Taira M, Taira K. 2000. Tubulointerstitial nephritis associated with Legionnaires' disease. Internal Medicine 39:150-3

15. Tokuda Y. 2000. Bacterial versus viral meningitis: comparison of the old and the new clinical prediction models. In Critical Care, p. 183

16. Nakamura Y, Kishaba Y, Masuda T, Nakazato N, Tokuda Y. 2001. Neuroleptic Malignant Syndrome in the Patient with Parkinson's disease. Journal of Okinawa Chubu Hospital 27:9-12

17. Nakazato N, Tokuda Y. 2001. Short term Outcomes of Oldest Old Patients. In Journal of General Internal Medicine

18. Tokuda Y, Miyagi S. 2001. Oxygen treatment for acute severe asthma. Home oxygenation would be more effective. BMJ 323:1069

19. Tokuda Y, Nakazato N, Maeshiro M, Miyagi S. 2001. US-Japan Collaboration in Graduate Medical Education. In Journal of General Internal Medicine

20. Joishy S, Tokuda Y, Tamaki K. 2002. Applied clinical ethics for house staff physicians in Japan: Integral component of end-of-life care. Journal of Okinawa Chubu Hospital 28:25-35

21. Tokuda Y, Koketsu H. 2002. High mortality in hospitalized elderly patients with feeding tube placement. Internal Medicine 41:613-6

22. Tokuda Y, Nakazato N. 2002. Cranial CT before lumbar puncture in suspected meningitis. New England Journal of Medicine 346:1248-51; author reply -51

23. Koketsu H, Tokuda Y, Stein GH. 2003. Risk Factors For Mortality From Infectious Diseases Among Elderly From Long-Term Care Facilities. Internet Journal of Infectious Diseases 2:1

24. Tokuda Y, Kishaba Y, Kato J, Nakazato N. 2003. Assessing the validity of a model to identify patients for lymph node biopsy. Medicine (Baltimore) 82:414-8

25. Tokuda Y, Nakazato N, Stein GH. 2003. Pupillary evaluation for differential diagnosis of coma. Postgraduate Medical Journal 79:49-51

26. Tokuda Y, Nakazato N, Tamaki K. 2004. Evaluation of end of life care in cancer patients at a teaching hospital in Japan. Journal of Medical Ethics 30:264-7

27. Kishimoto M, Lim HY, Tokuda Y, Narita M, Kitazono H, Ito H, Seto TB, Sumida KN, Gelber RP. 2005. Prevalence of venous thromboembolism at a teaching hospital in Okinawa, Japan. Thrombosis & Haemostasis 93:876-9

28. Tokuda Y. 2005. Risk factors for acute myocardial infarction among Okinawans. Journal of Nutrition, Health, and Aging 9:272-6

29. Tokuda Y. 2005. Ethics and Science of Tobacco Control. Primary Care Japan 3:17-27

30. Tokuda Y, Miyasato H, Stein GH. 2005. A simple prediction algorithm for bacteraemia in patients with acute febrile illness. Quarterly Journal of Medicine 98:813-20

31. Tokuda Y, Miyasato H, Stein GH, Kishaba T. 2005. The degree of chills for risk of bacteremia in acute febrile illness. American Journal of Medicine 118:1417

32. Tokuda Y, Stein GH. 2005. Serum lipids as protective factors for subarachnoid hemorrhage. Journal of Clinical Neuroscience 12:538-41

33. Tokuda Y. 2006. Telemedicine in Okinawa. Okinawa Wellness and Longevity Journal 1:1-6

34. Tokuda Y, Kashima M, Kayo M, Nakazato N, Stein GH. 2006. Cocoa supplementation for copper deficiency associated with tube feeding nutrition. Internal Medicine 45:1079-85

35. Tokuda Y, Kikuchi M, Takahashi O, Stein GH. 2006. Prehospital management of sarin nerve gas terrorism in urban settings: 10 years of progress after the Tokyo subway sarin attack. Resuscitation 68:193-202

36. Tokuda Y, Matsushima D, Stein GH, Miyagi S. 2006. Intrapleural fibrinolytic agents for empyema and complicated parapneumonic effusions: a meta-analysis. Chest 129:783-90

37. Birrer R, Tokuda Y, Takara T. 2007. Hypoxic Hepatopathy: Pathophysiology and Prognosis Internal Medicine 46:1063-70

38. Chinen K, Tokuda Y, Sakamoto A, Fujioka Y. 2007. Fungal infections of the heart: A clinicopathologic study of 50 autopsy cases. Pathology Research & Practice 203:705-15

39. Gushiken N, Yoshimura H, Toyoura M, Fujiwara N, Tokuda Y. 2007. Severe Retinopathy in Fulminant Juvenile Dermatomyositis. General Medicine 8:25-8

40. Jacobs JL, Takahashi O, Hirai S, Tokuda Y, Omata F, Fukui T. 2007. When fear trumps science: a case study for finding alternative research methods. BMJ 336:77

41. Lim H, Kishimoto M, Kitazono H, Ito H, Narita M, Gelber R, Tokuda Y. 2007. Risk Factors for Venous Thromboembolism in Japan: A Hospital-Based Case-Control Study. Hawai'i Medical Journal 66:236-9

42. Morishita K, Gushimiyagi M, Hashiguchi M, Stein GH, Tokuda Y. 2007. Clinical prediction rule to distinguish pelvic inflammatory disease from acute appendicitis in women of childbearing age. American Journal of Emergency Medicine 25:152-7

43. Moromizato T, Harano K, Oyakawa M, Tokuda Y. 2007. Diagnostic performance of pyogenic vertebral osteomyelitis. Internal Medicine 46:11-6

44. Takahashi O, Noguchi Y, Omata F, Tokuda Y, Fukui T. 2007. Probiotics in the prevention of traveler's diarrhea: meta-analysis. Journal of Clinical Gastroenterology 41:336-7

45. Tokuda Y. 2007. Cocoa supplementation for copper deficiency. European Journal of Nutraceuticals & Functional Foods (AgroFOOD industry hi-tech) 18:11-3

46. Tokuda Y. 2007. Chemical terrorism: Sarin nerve gas and other toxic nerve agents. In Global Terrorism Issues and Developments, ed. R Larche. New York: Nova Science Publishers. Number of.

47. Tokuda Y, Maezato K, Stein GH. 2007. The causes of hypercalcemia in Okinawan patients: an international comparison. Internal Medicine 46:23-8

48. Tokuda Y, Miyagi S. 2007. Physical Diagnosis of Chronic Obstructive Pulmonary Disease. Internal Medicine 46:1885-91

49. Tokuda Y, Ohde S, Takahashi O, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. 2007. Musculoskeletal pain in Japan: prospective health diary study. Rheumatology International 28:7-14

50. Tokuda Y, Ohde S, Takahashi O, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. 2007. Influence of Socioeconomic Factors on Symptom-Related Access to Health Care. Primary Care Japan 5:12-21

51. Tokuda Y, Takahashi O, Ohde S, Ogata H, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. 2007. Health locus of control and use of conventional and alternative care: a cohort study. British Journal of General Practice 57:643-9

52. Tokuda Y, Takahashi O, Ohde S, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. 2007. Gastrointestinal symptoms in a Japanese population: A health diary study. World Journal of Gastroenterology 13:572-8

53. Abe T, Ohde S, Ishimatsu S, Ogata H, Hasegawa T, Nakamura T, Tokuda Y. 2008. Effects of meteorological factors on the onset of subarachnoid hemorrhage: A time-series analysis. J Clin Neuroscience 15:1005-10

54. Abe T, Tokuda Y, Ishimatsu S. 2008. A new cardiopulmonary resuscitation method using only rhythmic abdominal compression is hard. American Journal of Emergency Medicine 26:625

55. Abe T, Tokuda Y, Ishimatsu S. 2008. Yubitsume (self-amputation). Emergency Medicine Journal 25:702

56. Abe T, Tokuda Y, Ohde S, Ishimatsu S, Nakamura T, Birrer R. 2008. The influence of meteorological factors on the occurrence of trauma and motor vehicle collisions in Tokyo. Emergency Medicine Journal 25:769-72

57. Abe T, Tokuda Y, Stein G, Ishimatsu S, Birrer R. 2008. Risk Factors Associated with Prolonged Hospital Stay in Admitted Patients with Psychotropic Drug Overdose. Open Critical Care Medicine Journal 1:12-6

58. Horinouchi H, Tokuda Y, Nishimura N, Terai M, Takahashi T, Ohde S, Ishikawa R, Fukui T. 2008. Influence of Residents' Workload, Mental State and Job Satisfaction on Procedural Error:a prospective daily questionnaire-based study. General Medicine 9:57-64

59. Jacobs JL, Tokuda Y, Ohde S. 2008. Aging policy-makers take note: future physicians are not being taught about healthy longevity. Journal of American Geriatric Society 56:1375-6

60. Kowada A, Takahashi O, Shimbo T, Ohde S, Tokuda Y, Fukui T. 2008. Cost Effectiveness of Interferon-gamma Release Assay for Tuberculosis Contact Screening in Japan. Mol Diagn Ther 12:235-51

61. Martins H, Tokuda Y, Fukui T. 2008. Management matters. Igaku Kyoiku 39:411-6

62. Norisue Y, Tokuda Y, Koizumi M, Kishaba T, Miyagi S. 2008. Phasic characteristics of inspiratory crackles of bacterial and atypical pneumonia. Postgrad Med J 84:432-6

63. Ohde S, Takahashi O, Jacobs J, Tokuda Y, Omata F, Hinohara S, Fukui T. 2008. Japanese medical residents' self-assessed confidence in clinical research: skills improve with experience in scholarly activities. General Medicine 9:81-2

64. Ohde S, Tokuda Y, Takahashi O, Yanai H, Hinohara S, Fukui T. 2008. Dysmenorrhea among Japanese women. International Journal of Gynecology & Obstetrics 100:13-7

65. Omata F, Sato S, Tokuda Y, Takahashi O, Fukui T. 2008. Autoimmune hemolytic anemia associated with primary biliary cirrhosis. General Medicine 9:65-70

66. Ono R, Higashi T, Suzukamo Y, Konno S, Takahashi O, Tokuda Y, Rhaman M, Shimbo T, Endo H, Hinohara S, Fukui T, Fukuhara S. 2008. Higher internality of health locus of control is associated with the use of complementary and alternative medicine providers among patients seeking care for acute low-back pain. Clin J Pain 24:725-30

67. Tokuda Y, Hinohara S. 2008. Redefining the age of elderly in Japan. Journal of the American Geriatrics Society 56:573-4

68. Tokuda Y, Hinohara S. 2008. Geriatric Nation and Redefining the Elderly in Japan. International Journal of Gerontology 2:154-7

69. Tokuda Y, Hinohara S, Fukui T. 2008. Introducing a new medical school system into Japan. Ann Acad Med Singapore 37:800-2

70. Tokuda Y, Inoguchi T. 2008. Trust in the Mass Media and the Healthcare System, Interpersonal Trust and Self-Rated Health: A Population-based Study in Japan. Asian Journal of Epidemiology 1:29-39

71. Tokuda Y, Inoguchi T. 2008. Interpersonal Mistrust and Unhappiness Among Japanese People. Social Indicators Research 89:349-60

72. Tokuda Y, Jimba M, Yanai H, Fujii S, Inoguchi T. 2008. Interpersonal trust and quality-of-life: a cross-sectional study in Japan. PLoS ONE 3:e3985

73. Tokuda Y, Obara H, Nakazato N, Stein GH. 2008. Acute care hospital mortality of schizophrenic patients. Journal of Hospital Medicine 3:110-6

74. Tokuda Y, Ohde S, Takahashi O, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. 2008. Prospective health diary study for new onset chest symptoms in the Japanese general population. Internal Medicine 47:25-31

75. Tokuda Y, Ohde S, Takahashi O, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. 2008. Relationships between Working Status and Health or Healthcare Utilization among Japanese Elderly. Geriatrics & Gerontology International 8:32-40

76. Tokuda Y, Okamoto S, Yoshioka Y, Aizawa M, Tanaka M, Motomura K, Hayano K. 2008. The influence of medical jargon mixed with foreign terminology in the Japanese clinical environment. Internal Medicine 47:1329-34

77. Tokuda Y, Takahashi O, Ohde S, Shakudo M, Yanai H, Shimbo T, Fukuhara S, Hinohara S, Fukui T. 2008. Sociodemographic Characteristics for Use of Complementary and Alternative Medicine in Japan. General Medicine 9:31-9

78. Tokuda Y, Yoshioka Y, Aizawa M, Tanaka M, Ohde S, Motomura K, Naito A, Hayano K, Fukui T. 2008. Physicians' Use of Local Dialects during Communication with Patients. General Medicine 9:13-9

79. Abe T, Nagamine Y, Ishimatsu S, Tokuda Y. 2009. Spinal epidural hematoma after stretch exercise: a case report. Am J Emerg Med 27:902 e1-2

80. Abe T, Tokuda Y, Ishimatsu S. 2009. Predictors for good cerebral performance among adult survivors of out-of-hospital cardiac arrest. Resuscitation 80:431-6

81. Abe T, Tokuda Y, Ishimatsu S, Birrer RB. 2009. Usefulness of initial blood cultures in patients admitted with pneumonia from an emergency department in Japan. J Infect Chemother 15:180-6

82. Abe T, Tokuda Y, Ohde S, Ishimatsu S, Nakamura T, Birrer RB. 2009. The relationship of short-term air pollution and weather to ED visits for asthma in Japan. Am J Emerg Med 27:153-9

83. Chinen K, Tokuda Y, Aoki M. 2009. Clinical Problem Solving : Diagnostic Power of Gram Stain Examination. General Medicine 10:3-6

84. Jacobs JL, Ohde S, Takahashi O, Tokuda Y, Omata F, Fukui T. 2009. Use of surgical face masks to reduce the incidence of the common cold among health care workers in Japan: A randomized controlled trial. Am J Infect Control 37:417-9

85. Jacobs JL, Takahashi O, Ohde S, Tokuda Y, Omata F, Fukui T. 2009. PDA Usage by Japanese Resident Physicians Is Low. Methods Inf Med 48:475-9

86. Kiyoyama T, Tokuda Y, Shiiki S, Hachiman T, Shimasaki T, Endo K. 2009. Isopropyl alcohol compared with isopropyl alcohol plus povidone-iodine as skin preparation for prevention of blood culture contamination. J Clin Microbiol 47:54-8

87. Norisue Y, Onopa J, Kaneshiro M, Tokuda Y. 2009. Surfing as a risk factor for gastroesophageal reflux disease. Clin J Sport Med 19:388-93

88. Omata F, Brown WR, Tokuda Y, Takahashi O, Fukui T, Ueno F, Mine T. 2009. Modifiable risk factors for colorectal neoplasms and hyperplastic polyps. Internal Medicine 48:123-8

89. Omata F, Shibata M, Nakano M, Jacobs JL, Tokuda Y, Fukutake K, Takahashi O, Fukui T. 2009. Chronic hepatitis with eosinophilic infiltration associated with asthma. Internal Medicine 48:1945-9

90. Takahashi O, Ohde S, Jacobs JL, Tokuda Y, Omata F, Fukui T. 2009. Residents' experience of scholarly activities is associated with higher satisfaction with residency training. J Gen Intern Med 24:716-20

91. Tokuda Y, Aoki M, Kandpal SB, Tierney LM, Jr. 2009. Caught in the web: e-diagnosis. J Hosp Med 4:262-6

92. Tokuda Y, Barnett PB, Norisue Y, Konishi R, Kudo H, Miyagi S. 2009. Questionnaire survey for challenging cases of medical professionalism in Japan. Medical Teacher 31:502-7

93. Tokuda Y, Chinen K, Obara H, Joishy SK. 2009. Intervals between Symptom Onset and Clinical Presentation in Cancer Patients. Internal Medicine 48:899-905

94. Tokuda Y, Doba N, Butler JP, Paasche-Orlow MK. 2009. Health literacy and physical and psychological wellbeing in Japanese adults. Patient Educ Couns 75:411-7

95. Tokuda Y, Fujii S, Jimba M, Inoguchi T. 2009. The relationship between trust in mass media and the healthcare system and individual health: evidence from the AsiaBarometer Survey. BMC Medicine 7:4

96. Tokuda Y, Hayano K, Ozaki M, Bito S, Yanai H, Koizumi S. 2009. The interrelationships between working conditions, job satisfaction, burnout and mental health among hospital physicians in Japan: a path analysis. Industrial Health 47:166-72

97. Tokuda Y, Koizumi M, Stein GH, Birrer RB. 2009. Identifying low-risk patients for bacterial meningitis in adult patients with acute meningitis. Internal Medicine 48:537-43

98. Tokuda Y, Ohde S, Takahashi O, Hinohara S, Fukui T, Inoguchi T, Butler JP, Ueda S. 2009. Influence of Income on Health Status and Healthcare Utilization in Working Adults: an Illustration of Health among the Working Poor in Japan. Japanese Journal of Political Science 10:79-92

99. Tokuda Y, Okubo T, Ohde S, Jacobs J, Takahashi O, Omata F, Yanai H, Hinohara S, Fukui T. 2009. Assessing Items on the SF-8 Japanese Version for Health-Related Quality of Life: A Psychometric Analysis Based on the Nominal Categories Model of Item Response Theory. Value in Health 12:568-73

100. Tsugawa Y, Tokuda Y, Ohbu S, Okubo T, Cruess R, Cruess S, Ohde S, Okada S, Hayashida N, Fukui T. 2009. Professionalism Mini-Evaluation Exercise for medical residents in Japan: a pilot study. Medical Education 43:968-78

101. Tsunoda Y, Kondo T, Matsuda Y, Kobayashi H, Tokuda Y, Satoh H. 2009. A Key Film. J Emerg Med

102. Yamamoto Y, Yamazaki S, Hayashino Y, Takahashi O, Tokuda Y, Shimbo T, Fukui T, Hinohara S, Miyachi Y, Fukuhara S. 2009. Association between frequency of pruritic symptoms and perceived psychological stress: a Japanese population-based study. Arch Dermatol 145:1384-8

103. Chinen K, Tokuda Y, Fujiwara M, Fujioka Y. 2010. Pulmonary tumor thrombotic microangiopathy in patients with gastric carcinoma: An analysis of 6 autopsy cases and review of the literature. Pathol Res Pract 206:682-9

104. Komatsu I, Tokuda Y, Shimada G, Jacobs JL, Onodera H. 2010. Development of a simple model for predicting need for surgery in patients who initially undergo conservative management for adhesive small bowel obstruction. Am J Surg 200:215-23

105. Nishizaki Y, Tokuda Y, Sato E, Kato K, Matsumoto A, Takekata M, Terai M, Watanabe C, Lim Y, Ohde S, Ishikawa R. 2010. Relationship between nursing workloads and patient safety incidents. Journal of Multidisciplinary Healthcare 3:49-54

106. Omata F, Deshpande G, Tokuda Y, Takahashi O, Ohde S, Carr-Locke DL, Jacobs JL, Mine T, Fukui T. 2010. Meta-analysis: somatostatin or its long-acting analogue, octreotide, for prophylaxis against post-ERCP pancreatitis. J Gastroenterol 45:885-95

107. Sakamoto F, Yamada H, Suzuki C, Sugiura H, Tokuda Y. 2010. Increased use of alcohol-based hand sanitizers and successful eradication of methicillin-resistant Staphylococcus aureus from a neonatal intensive care unit: A multivariate time series analysis. Am J Infect Control 38:529-34

108. Shimizu T, Tokuda Y. 2010. Necrotizing fasciitis. Internal Medicine 49:1051-7

109. Stein GH, Shibata A, Bautista M, Tokuda Y. 2010. Webinar: An interactive Clinical Seminars for Japanese Medical Students. General Medicine 11:87-90

110. Takahashi O, Ohde S, Jacobs JL, Tokuda Y, Yanai H, Okubo T, Shimbo T, Fukuhara S, Hinohara S, Fukui T. 2010. Population-level preferences for primary care physicians' characteristics in Japan: a structural equation modeling. Internal Medicine 49:125-30

111. Tokuda Y, Abe T, Ishimatsu S, Hinohara S. 2010. Ambulance Transport of the Oldest Old in Tokyo: A Population-Based Study. J Epidemiol 20:468-72

112. Tokuda Y, Goto E, Otaki E, Jacobs JL, Omata F, Shapiro M, Soejima K, Ishida Y, Ohde S, Takahashi O, Fukui T. 2010. Educational environment of university and non-university hospitals in Japan International Journal of Medical Education 1:10-4

113. Tokuda Y, Goto E, Otaki J, Jacobs J, Omata F, Obara H, Shapiro M, Soejima K, Ishida Y, Ohde S, Takahashi O, Fukui T. 2010. Undergraduate educational environment, perceived preparedness for postgraduate clinical training, and pass rate on the National Medical Licensure Examination in Japan. BMC Medical Education 10:35-44

114. Tokuda Y, Okubo T, Yanai H, Doba N, Paasche-Orlow MK. 2010. Development and Validation of a 15-Item Japanese Health Knowledge Test. J Epidemiol 20:319-28

115. Tokuda Y, Okubo T, Yanai H, Jacobs J, Ohde S, Takahashi O, Omata F, Hinohara S, Fukui T. 2010. Comparison of health locus of control between physicians and the general public. Health Education Journal 69:63-73

116. Tokuda Y, Omata F, Tsugawa Y, Maesato K, Momotura K, Fujinuma A, Stein GH, Cook EF. 2010. Vital sign triage to rule out diabetic ketoacidosis and non-ketotic hyperosmolar syndrome in hyperglycemic patients. Diabetes Res Clin Pract 87:366-71

117. Abe T, Tokuda Y. 2011. Chest-compression-only versus standard CPR. Lancet 377:718

118. Abe T, Tokuda Y, Cook EF. 2011. Time-based partitioning model for predicting neurologically favorable outcome among adults with witnessed bystander out-of-hospital CPA. PLoS ONE 6:e28581

119. Abe T, Tokuda Y, Ishimatsu S, Stein GH. 2011. Spinal dural arteriovenous fistula incidentally discovered. J Emerg Trauma Shock 4:299

120. Alkhatib L, Albtoush O, Bataineh N, Gharaibeh K, Matalka I, Tokuda Y. 2011. Extragastrointestinal Stromal Tumor (EGIST) in the abdominal wall: Case report and literature review. Int J Surg Case Rep 2:253-5

121. Arima T, Nagamine Y, Obara H, Tokuda Y. 2011. Clinical Problem Solving: A repetitive visitor to the emergency room. General Medicine 12:5-10

122. Kondo Y, Abe T, Kohshi K, Tokuda Y, Cook EF, Kukita I. 2011. Revised trauma scoring system to predict in-hospital mortality in the emergency department: Glasgow Coma Scale, age and systolic blood pressure score. Crit Care 15:R191

123. Ohde S, Hayashi A, Takahasi O, Yamakawa S, Nakamura M, Osawa A, Shapiro ML, Deshpande GA, Tokuda Y, Omata F, Ishida Y, Soejima K, Hinohara S, Fukui T. 2011. A 2-week prognostic prediction model for terminal cancer patients in a palliative care unit at a Japanese general hospital. Palliat Med 25:170-6

124. Ono R, Higashi T, Takahashi O, Tokuda Y, Shimbo T, Endo H, Hinohara S, Fukui T, Fukuhara S. 2011. Sex differences in the change in health-related quality of life associated with low back pain. Qual Life Res 21:1705-11

125. Sato K, Yamazaki S, Hayashino Y, Takegami M, Tokuda Y, Takahashi O, Shimbo T, Hinohara S, Fukui T, Fukuhara S. 2011. Associations between Hours Worked, Symptoms and Health Resource Utilization among Full-time Male Japanese Workers. J Occup Health 53:197-204

126. Shimizu T, Tokuda Y. 2011. Acute urinary retention. Internal Medicine 50:2255

127. Takahashi Y, Sakai M, Tokuda Y, Takahashi O, Ohde S, Nakayama T, Fukuhara S, Fukui T, Shimbo T. 2011. The relation between self-reported body weight and health-related quality of life: a cross-sectional study in Japan. J Public Health (Oxf) 33:518-26

128. Tokuda Y. 2011. Benchmarking the Age of Elderly in Japan. General Medicine 12:3-4

129. Tokuda Y, Goto E, Otaki J, Omata F, Shapiro M, Soejima K, Ishida Y, Ohde S, Takahashi O, Fukui T. 2011. The New Japanese Postgraduate Medical Education and Quality of Emergency Medical Care. J Emerg Med 43:494-501

130. Tokuda Y, Kishida N, Konishi R, Koizumi S. 2011. Cognitive error as the most frequent contributory factor in cases of medical injury: A study on verdict's judgment among closed claims in Japan. J Hosp Med 6:109-14

131. Tsugawa Y, Ohbu S, Cruess R, Cruess S, Okubo T, Takahashi O, Tokuda Y, Heist BS, Bito S, Itoh T, Aoki A, Chiba T, Fukui T. 2011. Introducing the Professionalism Mini-Evaluation Exercise (P-MEX) in Japan: Results From a Multicenter, Cross-Sectional Study. Acad Med 86:1026-31

132. Yoshida K, Tokuda Y, Oshikawa H, Utsunomiya M, Kobayashi T, Kimura M, Deshpande GA, Matsui K, Kishimoto M. 2011. An observational study of tocilizumab and TNF-{alpha} inhibitor use in a Japanese community hospital: different remission rates, similar drug survival and safety. Rheumatology (Oxford) 50:2093-9

133. Abe T, Fujihara K, Kono M, Kumagai R, Ono K, Tokuda Y. 2012. Clinical Problem Solving: What Causes Tachycardia in a Hip Injury? General Medicine 13:5-10

134. Abe T, Tokuda Y, Kitahara T, Sakai S, Toyama M, Watanabe S. 2012. Syncope Caused by Portopulmonary Hypertension : A Case Report General Medicine 13:113-6

135. Barata AN, Tokuda Y, Martins HM. 2012. Comparing healthcare systems: Considering Japan and Portugal. Revista Portuguesa de Saude Publica

136. Doba N, Tokuda Y, Goldstein NE, Kushiro T, Hinohara S. 2012. A pilot trial to predict frailty syndrome: The Japanese Health Research Volunteer Study. Exp Gerontol 47:638-43

137. Hayashi N, Nakamura S, Tokuda Y, Shimoda Y, Yagata H, Yoshida A, Ota H, Hortobagyi GN, Cristofanilli M, Ueno NT. 2012. Prognostic value of HER2-positive circulating tumor cells in patients with metastatic breast cancer. Int J Clin Oncol 17:96-104

138. Hayashi N, Nakamura S, Tokuda Y, Yagata H, Yoshida A, Ota H, Hortobagyi GN, Cristofanilli M, Ueno NT. 2012. Serum HER2 levels determined by two methods in patients with metastatic breast cancer. Int J Clin Oncol 17:55-62

139. Imanishi M, Sato M, Tokuda Y. 2012. Endoscopic capture of Anisakis larva (a video demonstration). BMJ Case Rep 2012

140. Ishimaru N, Suzuki H, Tokuda Y, Takano T. 2012. Severe Legionnaires' Disease with Pneumonia and Biopsy-Confirmed Myocarditis Most Likely Caused by Legionella pneumophila Serogroup 6. Internal Medicine 51:3207-12

141. Kato M, Seyama Y, Kanai T, Fujiwara K, Omoto M, Moriyama N, Nishiki K, Tokuda Y. 2012. Clinical Problem Solving : Masked Face of Posterior Illness General Medicine 13:65-8

142. Kimura M, Tokuda Y, Oshiawa H, Yoshida K, Utsunomiya M, Kobayashi T, Deshpande GA, Matsui K, Kishimoto M. 2012. Clinical characteristics of patients with remitting seronegative symmetrical synovitis with pitting edema compared to patients with pure polymyalgia rheumatica. J Rheumatol 39:148-53

143. Nishizaki Y, Watanabe T, Tokuda Y, Futatsuyama M, Furukawa K, Mori N, Tsugawa Y, Yuki H, Tamagaki K, Taki F. 2012. Renal Function and Mortality in Patients with Infective Endocarditis. General Medicine 13:19-24

144. Shimizu M, Kinoshita K, Hattori K, Ota Y, Kanai T, Kobayashi H, Tokuda Y. 2012. Physical signs of dehydration in the elderly. Internal Medicine 51:1207-10

145. Shimizu T, Kinoshita K, Tokuda Y. 2012. Diphyllobothrium nihonkaiense infection linked to chilled salmon consumption. BMJ Case Rep 2012

146. Shimizu T, Tokuda Y. 2012. Exercise-induced anaphylaxis. BMJ Case Rep 2012

147. Shimizu T, Tokuda Y. 2012. Hairy tongue. BMJ Case Rep 2012

148. Shimizu T, Tokuda Y. 2012. System 3 diagnostic process: the lateral approach. International Journal of General Medicine 5:873-4

149. Shimizu T, Tokuda Y. 2012. Pivot and cluster strategy: a preventive measure against diagnostic errors. International Journal of General Medicine 5:917-21

150. Shimizu T, Tokuda Y. 2012. Superior mesenteric artery dissection. BMJ Case Rep 2012

151. Shimizu T, Tokuda Y. 2012. Real-world medical diagnosis: Intuitive process revisited (review). International Journal of Medicine and Medical Sciences 4:177-9

152. Shimizu T, Tokuda Y. 2012. Miller Fisher syndrome linked to Norovirus infection. BMJ Case Rep 2012

153. Tokuda Y. 2012. Case 23-2012: A man with abdominal pain and weight loss. N Engl J Med 367:1670; author reply 1-2

154. Tokuda Y. 2012. Re: When financial incentives do more good than harm: a checklist. BMJ 345:e5047

155. Abe T, Ishimatsu S, Tokuda Y. 2013. Descriptive analysis of patients' EMS use related to severity in Tokyo: a population-based observational study. PLoS One 8:e59738

156. Abe T, Tokuda Y. 2013. Bilateral carotid arteries occlusion. BMJ case reports 2013

157. Abe T, Tokuda Y. 2013. The Triage in a Mild and Mini Disaster General Medicine 14:76-7

158. Abe T, Watanabe S, Mizuno A, Toyama M, Tokuda Y. 2013. A Model for Predicting Angiographically Normal Coronary Arteries in Survivors of Out of Hospital Cardiac Arrest. Circulation 128:A122

159. Doba N, Tokuda Y, Tomiyama H, Goldstein NE, Kushiro T, Hinohara S. 2013. Changes in ankle brachial pulse wave velocity during a five-year follow-up period in older Japanese adults: sub-analysis results of the health research volunteer study in Japan. Internal Medicine 52:21-7

160. Itoi S, Tokuda Y, Ohara G, Kagohashi K, Satoh H. 2013. Acute Eosinophilic Pneumonia in a Teenager as a Result of Smoking : Importance of Differential Diagnosis General Medicine 14:64-6

161. Kinoshita K, Hattori K, Ota Y, Kanai T, Shimizu M, Kobayashi H, Tokuda Y. 2013. The measurement of axillary moisture for the assessment of dehydration among older patients: a pilot study. Exp Gerontol 48:255-8

162. Kinoshita K, Tsunoda Y, Watanabe S, Tokuda Y. 2013. Spontaneous coronary artery dissection in a patient with bacterial meningitis. BMJ Case Rep 2013

163. Kobayashi H, Suzuki T, Tokuda Y. 2013. Pyogenic ventriculitis following urosepsis caused by Escherichia coli. BMJ Case Rep 2013

164. Kobayashi T, Kishimoto M, Swearingen CJ, Filopoulos MT, Ohara Y, Tokuda Y, Oshikawa H, Yoshida K, Utsunomiya M, Kimura M, Okada M, Matsui K, Yazici Y. 2013. Differences in clinical manifestations, treatment, and concordance rates with two major sets of criteria for Behcet's syndrome for patients in the US and Japan: data from a large, three-center cohort study. Mod Rheumatol 23:547-53

165. Miyauchi R, Kinoshita K, Tokuda Y. 2013. Clarithromycin-induced haemorrhagic colitis. BMJ Case Rep 2013

166. Sakakura K, Takayashiki N, Tokuda Y, Satoh H. 2013. Biliary tract compression caused by a giant abdominal aneurysm. Internal Medicine 52:925

167. Sawa A, Abe T, Omoto M, Fujiwara K, Kobayashi H, Tokuda Y. 2013. Lactic Acidosis with Metformin Use in a Patient with Type 1 Diabetes Mellitus General Medicine 14:72-5

168. Shimizu T, Matsumoto K, Tokuda Y. 2013. Effects of the use of differential diagnosis checklist and general de-biasing checklist on diagnostic performance in comparison to intuitive diagnosis. Med Teach 35:e1218-29

169. Shimizu T, Nozaki H, Tokuda Y. 2013. Steinert's disease. BMJ Case Rep 2013

170. Shimizu T, Tokuda Y. 2013. Osler's node. BMJ case reports 2013

171. Shimizu T, Tokuda Y. 2013. Intravesical migration of intrauterine device. BMJ case reports 2013

172. Shimizu T, Tokuda Y. 2013. Visible intestinal peristalsis. BMJ Case Rep 2013

173. Shimizu T, Tsugawa Y, Tanoue Y, Konishi R, Nishizaki Y, Kishimoto M, Shiojiri T, Tokuda Y. 2013. The hospital educational environment and performance of residents in the General Medicine In-Training Examination: a multicenter study in Japan. Int J Gen Med 6:637-40

174. Suzuki H, Senda J, Yamashita K, Tokuda Y, Kanesaka Y, Kotaki N, Ishihara H, Ishikawa H. 2013. Impact of intensive infection control team activities on the acquisition of methicillin-resistant Staphylococcus aureus, drug-resistant Pseudomonas aeruginosa and the incidence of Clostridium difficile-associated disease. J Infect Chemother 19:1047-52

175. Suzuki H, Shichi D, Tokuda Y, Ishikawa H, Maeno T, Nakamura H. 2013. Pneumococcal vertebral osteomyelitis at three teaching hospitals in Japan, 2003-2011: analysis of 14 cases and a review of the literature. BMC Infect Dis 13:525

176. Suzuki H, Tokuda Y, Kurihara Y, Suzuki M, Nakamura H. 2013. Adult pneumococcal meningitis presenting with normocellular cerebrospinal fluid: two case reports. J Med Case Rep 7:294

177. Suzuki H, Tokuda Y, Shichi D, Hitomi S, Ishikawa H, Maeno T, Nakamura H. 2013. A retrospective cohort study of panipenem/betamipron for adult pneumococcal bacteremia at three teaching hospitals in Japan. J Infect Chemother 19:607-14

178. Suzuki H, Tokuda Y, Shichi D, Ishikawa H, Maeno T, Nakamura H. 2013. Morbidity and mortality among newly hospitalized patients with community-acquired pneumococcal bacteremia: A retrospective cohort study in three teaching hospitals in Japan. Geriatr Gerontol Int 13:607-15

179. Takata Y, Stein GH, Endo K, Arai A, Kohsaka S, Kitano Y, Honda H, Kitazono H, Tokunaga H, Tokuda Y, Obika M, Miyoshi T, Kataoka H, Terasawa H. 2013. Content analysis of medical students' seminars: a unique method of analyzing clinical thinking. BMC Med Educ 13:156

180. Tokuda Y, Feldman MD. 2013. Direct to consumer unproved screening tests turn a profit in Japan. BMJ 347:f4725

181. Abe T, Takahashi O, Saitoh D, Tokuda Y. 2014. Association between helicopter with physician versus ground emergency medical services and survival of adults with major trauma in Japan. Crit Care 18:R146

182. Abe T, Tokuda Y. 2014. Recurrent posterior reversible encephalopathy syndrome of the brainstem in a hypertensive patient with end-stage renal disease. J Emerg Trauma Shock 7:242-3

183. Chuganji E, Abe T, Kobayashi H, Nakano N, Kanai T, Ohara G, Takayashiki N, Noguchi M, Morishita Y, Aoki M, Tokuda Y. 2014. Fatal pulmonary co-infection with pneumocystis and cytomegalovirus in a patient with acquired immunodeficiency syndrome. Internal Medicine 53:1575-8

184. Fushiki Y, Kinoshita K, Tokuda Y. 2014. Polypharmacy and Adverse Drug Events Leading to Acute Care Hospitalization in Japanese Elderly General Medicine 15:110-6

185. Hamano J, Tokuda Y. 2014. Inappropriate Prescribing Among Elderly Home Care Patients in Japan: Prevalence and Risk Factors. J Primary Care Community Health 5:90-6

186. Hamano J, Tokuda Y. 2014. Risk Factors and Specific Prescriptions Related to Inappropriate Prescribing among Japanese Elderly Home Care Patients General Medicine 15:117-25

187. Hosoi T, Dhaliwal G, Tokuda Y. 2014. Amyloidosis in bilateral external auditory canals. BMJ Case Rep 2014

188. Iriyama H, Kato M, Nogami M, Tokuda Y. 2014. Edamame (green soy beans) biliary stones. BMJ Case Rep 2014

189. Kamata K, Tokuda Y. 2014. Rapid diagnosis of Campylobacter jejuni by stool Gram stain examination. BMJ Case Rep 2014

190. Matsuoka R, Takayashiki N, Chino Y, Tokuda Y. 2014. Fatal Full-blown Systemic Lupus Erythematosus. Internal Medicine 53:1733-4

191. Nakano H, Watari T, Suganami Y, Tokuda Y. 2014. A navel stone mimicking a urachal sinus. BMJ Case Rep 2014

192. Nishiguchi S, Branch J, Suganami Y, Kitagawa I, Tokuda Y. 2014. Effectiveness of early ureteric stenting for urosepsis associated with urinary tract calculi. Internal Medicine 53:2205-10

193. Sakamoto F, Sakihama T, Saint S, Greene MT, Ratz D, Tokuda Y. 2014. Health care-associated infection prevention in Japan: The role of safety culture. Am J Infect Control 42:888-93

194. Sakihama T, Honda H, Saint S, Fowler KE, Shimizu T, Kamiya T, Sato Y, Arakawa S, Lee JJ, Iwata K, Mihashi M, Tokuda Y. 2014. Hand Hygiene Adherence Among Health Care Workers at Japanese Hospitals: A Multicenter Observational Study in Japan. J Patient Saf 12:11-7

195. Shimizu T, Yamamoto Y, Hosoi T, Kinoshita K, Tokuda Y. 2014. MRSA toxic shock syndrome associated with surgery for left leg fracture and co-morbid compartment syndrome. Journal of Acute Disease 3:82-4

196. Stein GH, Tokunaga H, Ando H, Obika M, Miyoshi T, Tokuda Y, Bautista M, Kataoka H, Terasawa H. 2014. Preliminary report of a Web-based instrument to assess and teach knowledge and clinical thinking to medical student. Int J Med Educ 5:1-6

197. Suzuki T, Tokuda Y. 2014. Face the truth: a 76-year-old man with chronic heart failure of unknown origin. BMJ Case Rep 2014

198. Tokuda Y. 2014. Case 38-2013: A man with fever and lymphadenopathy. N Engl J Med 370:1076-7

199. Tokuda Y. 2014. Young Japanese Generalist Physicians, Be Academic! A Message from the New Editor-in-Chief of General Medicine General Medicine 15:85-7

200. Watanabe T, Tokuda Y. 2014. Small bowel obstruction following the consumption of "sushi". Internal Medicine 53:2661-2

201. Watanuki S, Kinoshita K, Oda A, Kobayashi H, Satoh H, Tokuda Y. 2014. Occam's Razor or Hickam's dictum: a paraneoplastic or coincidental occurrence of lung cancer and Guillain-Barre syndrome. Internal Medicine 53:1569-73

202. Watanuki S, Kinoshita K, Tokuda Y. 2014. Acute graft occlusion of abdominal aorta after anaphylaxis. BMJ Case Rep 2014

203. Watari T, Shimizu T, Tokuda Y. 2014. Broca aphasia. BMJ Case Rep 2014

204. Watari T, Shimizu T, Tokuda Y. 2014. Rupture of megadolicho basilar artery anomaly. BMJ Case Rep 2014

205. Watari T, Terashima T, Tokuda Y. 2014. Coeliac artery compression syndrome as a cause of abdominal pain of unknown origin. BMJ Case Rep 2014

206. Abe T, Tamiya N, Kitahara T, Tokuda Y. 2015. Polypharmacy as a risk factor for hospital admission among ambulance‐transported old‐old patients. Acute Medicine & Surgery 3:107–13

207. Abe T, Tokuda Y, Watanabe S. 2015. Eight-vessel disease mimicking takotsubo cardiomyopathy. QJM

208. Abe T, Watanabe S, Mizuno A, Toyama M, Totten VY, Tokuda Y. 2015. A model for predicting angiographically normal coronary arteries in survivors of out-of-hospital cardiac arrest. J Intensive Care 3:32

209. Hamano J, Ozone S, Tokuda Y. 2015. A comparison of estimated drug costs of potentially inappropriate medications between older patients receiving nurse home visit services and patients receiving pharmacist home visit services: a cross-sectional and propensity score analysis. BMC health services research 15:73

210. Horiuchi M, Tokuda Y, Tagashira Y, Higuchi M, Honda H. Impact of Infectious Disease Consultation and Prospective Carbapenem Audit as an Antimicrobial Stewardship for Carbapenem Use at a Japanese Tertiary Care Center: An Interrupted Time Series Analysis. Proc. Open Forum Infectious Diseases, 2015, 2:1450: Oxford University Press

211. Kamata K, Suzuki H, Kanemoto K, Tokuda Y, Shiotani S, Hirose Y, Suzuki M, Ishikawa H. 2015. Clinical evaluation of the need for carbapenems to treat community-acquired and healthcare-associated pneumonia. Journal of Infection and Chemotherapy

212. Katayama K, Suzuki M, Seki Y, Mori N, Kanai T, Tokuda Y. 2015. Causes of New Onset Fever among Hospitalized Patients and Predictors for In-Hospital Mortality in a Teaching Hospital in Japan. General Medicine 16:84-9

213. Katayama K, Tokuda Y. 2015. Inter-arm Blood Pressure Difference by Takayasu’s Arteritis. General Medicine 16:45

214. Katayama K, Tokuda Y. 2015. Severe Paresthesia as a Rare Presenting Symptom of Subacute Thyroiditis. General Medicine 16:26-8

215. Kato M, Chino Y, Sato R, Kinoshita K, Tsuji H, Tokuda Y, Tamaoka A, Sumida T. 2015. Lateral medullary infarction in a patient with central nervous system lupus. International journal of rheumatic diseases

216. Kato M, Oishi Y, Inada M, Tokuda Y. 2015. Advanced Erosive Gout as a Cause of Fever of Unknown Origin. Korean journal of family medicine 36:146-9

217. Kinoshita K, Tsugawa Y, Barnett PB, Tokuda Y. 2015. Challenging cases of professionalism in Japan: improvement in understanding of professional behaviors among Japanese residents between 2005 and 2013. BMC medical education 15:42

218. Kinoshita K, Tsugawa Y, Shimizu T, Tanoue Y, Konishi R, Nishizaki Y, Shiojiri T, Tokuda Y. 2015. Impact of inpatient caseload, emergency department duties, and online learning resource on General Medicine In-Training Examination scores in Japan. Int J Gen Med 8:355-60

219. Miyata H, Ezoe S, Hori M, Inoue M, Oguro K, Okamoto T, Onishi K, Onozaki K, Sakakibara T, Takeuchi K, Tokuda Y, Yamamoto Y, Yamazaki M, Shibuya K, Health Care Advisory P. 2015. Japan's vision for health care in 2035. Lancet 385:2549-50

220. Miyauchi R, Matsuda Y, Tokuda Y. 2015. Urinary Tract Infection as a Cause of Hyperammonemic Encephalopathy. General Medicine 16:95-8

221. Miyauchi R, Tokuda Y. 2015. A Rare Case of Obsessive-Compulsive Disorder with Symptoms of Unexplained Somatic and Memory Problem. General Medicine 16:33-6

222. Sakihama T, Honda H, Saint S, Fowler KE, Kamiya T, Sato Y, Iuchi R, Tokuda Y. 2015. Improving healthcare worker hand hygiene adherence before patient contact: A multimodal intervention of hand hygiene practice in Three Japanese tertiary care centers. J Hosp Med 11:199-205

223. Satake S, Kaneko S, Yokozawa I, Shibasaki M, Mita O, Takase M, Miyashita S, Fujita Y, Stelling J, Tokuda Y. 2015. Clinical Usefulness of Multi-facility Microbiology Laboratory Database Analysis by WHONET. Journal of General and Family Medicine 16:138-42

224. Shinotsuka M, Shirai S, Tokuda Y. 2015. Deep Vein Thrombosis due to Metastatic Bladder Cancer. Internal Medicine 54:2527-8

225. Stein GH, Tokunaga H, Ando H, Obika M, Miyoshi T, Tokuda Y, Noguchi Y, Kataoka H, Terasawa H. 2015. Medical Students' Opinion of a Web-based Module to Teach Clinical Reasoning and Knowledge. General Medicine 16:76-83

226. Stein GH, Tokunaga H, Ando H, Obika M, Miyoshi T, Tokuda Y, Noguchi Y, Kinjo M, Kohsaka S, Honda H. 2015. Clinical reasoning Web-based prototypic module for tutors teaching 5th grade medical students: a pilot randomized study. General Medicine 16:13-25

227. Suzuki H, Hitomi S, Yaguchi Y, Tamai K, Ueda A, Kamata K, Tokuda Y, Koganemaru H, Kurihara Y, Ishikawa H. 2015. Prospective intervention study with a microarray-based, multiplexed, automated molecular diagnosis instrument (Verigene system) for the rapid diagnosis of bloodstream infections, and its impact on the clinical outcomes. Journal of Infection and Chemotherapy 21:849-56

228. Terada N, Kinoshita K, Taguchi S, Tokuda Y. 2015. Wernicke encephalopathy and pellagra in an alcoholic and malnourished patient. BMJ Case Rep 2015

229. Terada N, Tanaka T, Fujimoto T, Tokuda Y. 2015. Retroperitoneal panniculitis. BMJ Case Rep 2015

230. Tokuda Y. 2015. Current Status of Choosing Wisely in Japan. General Medicine 16:3-4

231. Tokuda Y. 2015. Diagnostic Error in Japan: Call for papers! Journal of General and Family Medicine 16:227-8

232. Tokuda Y. 2015. Choosing Wisely International and Japan. General Medicine 16:61-2

233. Tokuda Y. 2015. Lean Health Care: A Core Vision of the Health Care 2035. Journal of General and Family Medicine 16:129-30

234. Watanabe Y, Abe T, Tokuda Y. 2015. Another pharyngitis mimic: intraoral haematoma of the posterior wall of the pharynx in a patient on warfarin and drug-drug interaction. BMJ Case Rep 2015

235. Watanuki S, Honda H, Minemura N, Manesh RS, Raoult D, Tokuda Y. 2015. Sutton’s Law: Keep Going Where The Money Is. Journal of general internal medicine 30:1711-5

236. Watari T, Shimizu T, Tokuda Y. 2015. Crusted Scabies Initially Considered as Bullous Pemphigoid and Exacerbated by Steroid Use. Journal of General and Family Medicine 16:208-9

237. Watari T, Tokuda Y. 2015. Bleeding from a gut lesion as a cause of seizure. BMJ case reports 2015:bcr2014205619

238. Watari T, Tokuda Y. 2015. Drug-induced hemichorea. BMJ case reports 2015:bcr2014208872

239. Hamano J, Tokuda Y. 2016. Changes in vital signs as predictors of bacterial infection in home care: a multi-center prospective cohort study. Postgraduate Medicine:1-5

240. Hamano J, Tokuda Y, Kawagoe S, Shinjo T, Shirayama H, Ozawa T, Shishido H, Otomo S, Nagayama J, Baba M. 2016. Adding items that assess changes in activities of daily living does not improve the predictive accuracy of the Palliative Prognostic Index. Palliative medicine:0269216316650788

241. Honda H, Horiuchi M, Higuchi M, Murakami S, Tagashira Y, Tokuda Y. Effectiveness of Carbapenems and Piperacillin/Tazobactam Antimicrobial Stewardship at a Japanese Tertiary Care Center: The Impact on Changes in the Use of Other Antipseudomonal Agents. Proc. Open Forum Infectious Diseases, 2016, 3:990: Oxford University Press

242. Kamata K, Abe T, Kabayashi H, Tokuda Y. 2016. Chocolate Colored Urine. Journal of General and Family Medicine 17:252-3

243. Kurihara M, Tokuda Y. 2016. Jolt accentuation of neck pain: a novel physical finding for crowned dens syndrome. BMJ Case Reports 2016:bcr2016217128

244. Mizuno A, Shimizu T, Tokuda Y. 2016. MIMIc STEMI; Typical ECG of Takotsubo-cardiomyopathy. Journal of General and Family Medicine 17:105-8

245. Narita M, Tokuda Y, Barnett P. 2016. Professionalism of physicians at a major teaching hospital during the Fukushima nuclear disaster. QJM 109:447-8

246. Nishiguchi S, Branch J, Kitagawa I, Tokuda Y. 2016. Individuals Aged 75 and Older Dying at Night: A Retrospective Cohort Study in a Japanese Acute Care Hospital. Journal of the American Geriatrics Society 64:1516-8

247. Nishiguchi S, Inada H, Kitagawa I, Tokuda Y. 2016. Factors associated with a delayed diagnosis of pulmonary embolism. Diagnosis 3:37-41

248. Numata K, Suzuki M, Mashiko R, Tokuda Y. 2016. Lethal bilateral cerebral infarction caused by Moyamoya disease. QJM 109:501-

249. Sakihama T, Tokuda Y. 2016. Use of peripheral parenteral nutrition solutions as a risk factor for Bacillus cereus peripheral venous catheter-associated bloodstream infection at a Japanese tertiary care hospital: A case-control study. Japanese journal of infectious diseases 69:531-3

250. Sato S, Terane A, Nishiguchi S, Branch J, Kawada J, Kitagawa I, Tokuda Y. 2016. Intractable Hiccups and Nausea as a Principal Symptom of Neuromyelitis Optica in a Patient with a Prior History of Miller-Fisher Syndrome. Journal of General and Family Medicine 17:99-104

251. Sawagashira R, Watari T, Tokuda Y. 2016. Rapidly Progressive Tetraparesis with Ossification of the Posterior Longitudinal Ligament (OPLL). Journal of General and Family Medicine 17:158-9

252. Takada S, Nishimura M, Yamaguchi K, Tokuda Y. 2016. Hot dog lymphadenopathy of prostate cancer. BMJ Case Reports 2016:bcr2016217160

253. Tokuda Y. 2016. Ethical Basis of Recognizing Generalist Physicians in Japan. Journal of General and Family Medicine 17:189-90

254. Tokuda Y. 2016. Polypharmacy, Inappropriate Prescribing and Adverse Drug Events in Japan. Journal of General and Family Medicine 17:3-4

255. Tokuda Y, Aoki M. 2016. Action against Antimicrobial Resistance: Role of Generalist Physicians in Japan. Journal of General and Family Medicine 17:270-1

256. Tokuda Y, Birrer RB. 2016. Early Recognition of Sepsis. Anaesthesia, Critical Care and Pain Management 1:1

257. Torigoe K, Tokuda Y. 2016. Potential Usefulness of Diagnostic Reminder as Web-based Clinical Decision Support System. Journal of Health Science 4:297-303

258. Watari T, Sato S, Uojima H, Tokuda Y. 2016. Successful Combination Therapy Including Plasma Exchange for Severe Toxic Epidermal Necrolysis. Journal of General and Family Medicine 17:232-7

259. Birrer RB, Tokuda Y. 2017. Medicalization: A historical perspective. Journal of General and Family Medicine 18:48-51

260. Fujikawa T, Tokuda Y. 2017. Trousseau syndrome. BMJ Case Rep 2017

261. Hamano J, Tokuda Y. 2017. Authors reply: delta HR/BT as a possible predictor of severity or mortality, not a predictor of bacterial infection. Postgrad Med 129:779

262. Hamano J, Tokuda Y. 2017. Changes in vital signs as predictors of bacterial infection in home care: a multi-center prospective cohort study. Postgrad Med 129:283-7

263. Hamano J, Tokuda Y, Kawagoe S, Shinjo T, Shirayama H, Ozawa T, Shishido H, Otomo S, Nagayama J, Baba M, Tei Y, Hiramoto S, Suga A, Hisanaga T, Ishihara T, Iwashita T, Kaneishi K, Kuriyama T, Maeda T, Morita T. 2017. Adding items that assess changes in activities of daily living does not improve the predictive accuracy of the Palliative Prognostic Index. Palliat Med 31:258-66

264. Hanai S, Kinjo K, Uezato M, Tokuda Y. 2017. A disclosed diagnosis for 24 year's unknown illness. BMJ Case Rep 2017

265. Hanai S, Shinzato T, Inazu D, Tokuda Y. 2017. Hypercalcaemia caused by active pulmonary tuberculosis in an elderly person without fever or pulmonary symptoms. BMJ Case Rep 2017

266. Honda H, Ohmagari N, Tokuda Y, Mattar C, Warren DK. 2017. Antimicrobial Stewardship in Inpatient Settings in the Asia Pacific Region: A Systematic Review and Meta-analysis. Clin Infect Dis 64:S119-S26

267. Kamata K, Birrer RB, Tokuda Y. 2017. Travel medicine: Part 1–The basics. Journal of General and Family Medicine 18:52-5

268. Kamata K, Birrer RB, Tokuda Y. 2017. Travel medicine: Part 2—Special situations. Journal of General and Family Medicine

269. Katayama K, Tokuda Y. 2017. Severe Hypophosphatemia: Its Prevalence and Predictors Associated with In-hospital Mortality. Journal of General and Emergency Medicine 4:15-98

270. Katayama K, Tokuda Y. 2017. Mineralocorticoid responsive hyponatremia of the elderly: A systematic review. Medicine (Baltimore) 96:e7154

271. Krein SL, Greene MT, Apisarnthanarak A, Sakamoto F, Tokuda Y, Sakihama T, Fowler KE, Ratz D, Saint S. 2017. Infection Prevention Practices in Japan, Thailand, and the United States: Results From National Surveys. Clin Infect Dis 64:S105-S11

272. Kuriyama A, Takada T, Irie H, Sakuraya M, Katayama K, Kawakami D, Iwasaki H, Fowler KE, Tokuda Y, Saint S. 2017. Prevalence and Appropriateness of Urinary Catheters in Japanese Intensive Care Units: Results From a Multicenter Point Prevalence Study. Clin Infect Dis 64:S127-S30

273. Maruyama I, Tokuda Y. 2017. Changing work styles among Japanese healthcare professionals. J Gen Fam Med 18:152

274. Mizuno A, Iguchi H, Sawada Y, Hurley M, Nomura H, Hayashi K, Tokuda Y, Watanabe S, Yoshikawa A. 2017. The impact of carperitide usage on the cost of hospitalization and outcome in patients with acute heart failure: High value care vs. low value care campaign in Japan. Int J Cardiol 241:243-8

275. Nakanishi T, Goto T, Kobuchi T, Kimura T, Hayashi H, Tokuda Y. 2017. The effects of flipped learning for bystander cardiopulmonary resuscitation on undergraduate medical students. Int J Med Educ 8:430-6

276. Nemoto T, Tokuda Y, Hirose M, Naitoh Y, Yamasaki Y, Shimizu T, Nishisako H, Kunishima H, Matsuda T. 2017. Thoracic Aortic Graft Infection due to Candida Albicans with Multiple Embolism in the Left-side Vessels of the Body. Intern Med 56:1107-11

277. Nishizaki Y, Mizuno A, Shinozaki T, Okubo T, Tsugawa Y, Shimizu T, Konishi R, Yamamoto Y, Yanagisawa N, Shiojiri T. 2017. Educational environment and the improvement in the General Medicine In‐training Examination score. Journal of General and Family Medicine

278. Norisue Y, Tokuda Y, Juarez M, Uchimido R, Fujitani S, Stoeckel DA. 2017. Combined cumulative sum (CUSUM) and chronological environmental analysis as a tool to improve the learning environment for linear-probe endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) trainees: a pilot study. BMC Pulm Med 17:32

279. Numata K, Shimoda K, Shibata Y, Shioya A, Tokuda Y. 2017. The Development of Cerebral Venous Thrombosis after Tadalafil Ingestion in a Patient with Antiphospholipid Syndrome. Internal Medicine 56:1235-7

280. Sato R, Watari T, Tokuda Y. 2017. Fatal case of descending necrotising mediastinitis. BMJ Case Rep 2017

281. Shinotsuka M, Tokuda Y. 2017. Milk pancreatitis with hypertriglyceridemia and diabetic ketoacidosis. J Gen Fam Med 18:422-4

282. Sonoda K, Tanaka Y, Tokuda Y. 2017. A young man with multiple joint pains and fever: A case with the importance of accurate history taking. Journal of General and Family Medicine 18:79-81

283. Suzuki T, Tokuda Y, Kobayashi H. 2017. The Development of Yellow Nail Syndrome after the Implantation of a Permanent Cardiac Pacemaker. Intern Med 56:2667-9

284. Terada N, Hamada Y, Tokuda Y. 2017. Streptococcus dysagalactiae pyomyositis. Journal of General and Family Medicine

285. Terada N, Tokuda Y. 2017. Acute aortic dissection as a cause of shaking chills. Journal of General and Family Medicine

286. Tokuda Y. 2017. Welcome to the new online renewal of the journal. Journal of General and Family Medicine 18:4-

287. Tokuda Y, Aoki M, Machi J. 2017. Dr. N. L. Gault, Jr. (1920-2008) and History of Medical Education in South Korea and Okinawa. J Gen Fam Med 18:100-1

288. Tokuda Y, Barnett PB. 2017. Constructing a New US Military Base: A Health Threat to Okinawan People. Environmental Justice 10:23-5

289. Tokuda Y, Torigoe K, Matsumoto K, Yasuda H. 2017. Evaluation of a Web-based Diagnosis Reminder System for Difficult Diagnostic Reasoning. Journal of Health Science 5:107-9

290. Watari T, Sekine I, Tokuda Y. 2017. Fish hook injury: an easy removal using the string yank technique. BMJ Case Rep 2017

291. Watari T, Tokuda Y. 2017. Shiitake dermatitis. QJM

292. Fujikawa T, Tokuda Y. 2018. Ascites from intraperitoneal urine leakage after pelvic radiation. Cleve Clin J Med 85:188-9

293. Honda H, Murakami S, Tagashira Y, Uenoyama Y, Goto K, Takamatsu A, Hasegawa S, Tokuda Y. 2018. Efficacy of a Postprescription Review of Broad-Spectrum Antimicrobial Agents With Feedback: A 4-Year Experience of Antimicrobial Stewardship at a Tertiary Care Center. Open Forum Infect Dis 5:ofy314

294. Kamata K, Tokuda Y, Gu Y, Ohmagari N, Yanagihara K. 2018. Public knowledge and perception about antimicrobials and antimicrobial resistance in Japan: A national questionnaire survey in 2017. PLoS One 13:e0207017

295. Kishimoto K, Watari T, Tokuda Y. 2018. Pseudo-pneumothorax: skin fold is an excellent imitator. BMJ Case Rep 2018

296. Moromizato T, Garcia-Larsen V, Soeteman D, Wickner PG, Havens JM, Lund R, Eriguchi R, Tokuda Y, Murata K, Iseki K, Singh AK, Christopher KB. 2018. Addressing the gap in clinical research education: Implementation of the Introduction to Clinical Research Training-Japan program. J Gen Fam Med 19:188-90

297. Nagano H, Kamata K, Tokuda Y. 2018. Multiple gout tophi. QJM 111:419-20

298. Nakamura T, Watari T, Tokuda Y. 2018. Over-the-counter drug-induced lung injuries with both diffuse alveolar haemorrhage and diffuse alveolar damage. BMJ Case Rep 2018

299. Nishiguchi S, Tomiyama S, Kitagawa I, Tokuda Y. 2018. Delayed isolation of smear-positive pulmonary tuberculosis patients in a Japanese acute care hospital. BMC Pulm Med 18:94

300. Nishizaki Y, Shinozaki T, Kinoshita K, Shimizu T, Tokuda Y. 2018. Awareness of Diagnostic Error among Japanese Residents: a Nationwide Study. J Gen Intern Med 33:445-8

301. Sakaguchi K, Tokuda Y. 2018. Left shoulder pain in patients with old myocardial infarction could be a neuropathic pain from spinal epidural haematoma. BMJ Case Rep 2018

302. Shimizu T, Nemoto T, Tokuda Y. 2018. Effectiveness of a clinical knowledge support system for reducing diagnostic errors in outpatient care in Japan: A retrospective study. Int J Med Inform 109:1-4

303. Soshi M, Mizuta T, Tokuda Y. 2018. Subclinical cancer diagnosis fallacy. J Gen Fam Med 19:70-1

304. Soshi M, Mizuta T, Tokuda Y. 2018. Overtesting in Japan. J Gen Fam Med 19:42

305. Soshi M, Tokuda Y. 2018. Hidden Curricula, Ethics, and Professionalism. Ann Intern Med 169:425

306. Soshi M, Tokuda Y. 2018. Sexual harassment: The most challenging issue of medical professionalism in Japan. J Gen Fam Med 19:118-20

307. Takamatsu A, Tagashira Y, Ishii K, Morita Y, Tokuda Y, Honda H. 2018. Optimal timing of surgical antimicrobial prophylaxis in laparoscopic surgery: a before-after study. Antimicrob Resist Infect Control 7:126

308. Tanaka H, Ueda K, Watanuki S, Watari T, Tokuda Y, Okumura T. 2018. Disease vocabulary size as a surrogate marker for physicians' disease knowledge volume. PLoS One 13:e0209551

309. Tokuda Y. 2018. Physical Diagnosis of Cardiac Tamponade. Am J Med 131:e504

310. Tokuda Y, Soshi M, Okubo T, Nishizaki Y. 2018. Postgraduate medical education in Japan: Missed opportunity for learning clinical reasoning. J Gen Fam Med 19:152-3

311. Watari T, Tokuda Y. 2018. Double tongue signs in a case of submandibular space infection. BMJ Case Rep 2018

312. Watari T, Tokuda Y. 2018. Fever of unknown origin, bilateral sensorineural hearing loss with canal paresis and uveitis with iridocyclitis and episcleritis: a case of Cogan's syndrome. BMJ Case Rep 2018

313. Watari T, Tokuda Y. 2018. MRI thermal burn injury: an unrecognized consequence of wearing novel, high-tech undergarments. QJM 111:495-6

314. Watari T, Tokuda Y. 2018. Isolated Dissection of the Superior Mesenteric Artery. Intern Med 57:1059

315. Abe T, Tokuda Y, Shiraishi A, Fujishima S, Mayumi T, Sugiyama T, Deshpande GA, Shiino Y, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Hagiwara A, Yamakawa K, Takeyama N, Gando S, Group JSS. 2019. In-hospital mortality associated with the misdiagnosis or unidentified site of infection at admission. Crit Care 23:202

316. Hamano J, Tokuda Y. 2019. Prevalence of obstructive sleep apnea in primary care patients with hypertension. J Gen Fam Med 20:39-42

317. Murakami S, Hiroi J, Tokuda Y, Casabar E, Honda H. 2019. Methods of estimating vancomycin use in an inpatient setting: days of therapy versus therapeutic drug monitoring-based exposure days. Infect Control Hosp Epidemiol 40:375-9

318. Norisue Y, Santanda T, Homma Y, Tomita S, Saito S, Kataoka J, Fujimoto Y, Nabeshima T, Tokuda Y, Fujitani S. 2019. Ultrasonographic Assessment of Passive Cephalic Excursion of Diaphragm During Cough Expiration Predicts Cough Peak Flow in Healthy Adults. Respir Care

319. Sakamoto F, Asano K, Sakihama T, Saint S, Greene MT, Patel P, Ratz D, Tokuda Y. 2019. Changes in health care-associated infection prevention practices in Japan: Results from 2 national surveys. Am J Infect Control 47:65-8

320. Sonoda K, Kato R, Kojima H, Tokuda Y. 2019. Urinary tract bleeding from a urethral caruncle mimicking genital tract bleeding. BMJ Case Rep 12

321. Tokuda Y. 2019. Discriminations in medicine and public health: Moral challenges for modern Japanese physicians. J Gen Fam Med 20:46

322. Watari T, Hirose M, Midlov P, Tokuda Y, Kanda H, Okayama M, Yoshikawa H, Onigata K, Igawa M. 2019. Primary care doctor fostering and clinical research training in Sweden: Implications for Japan. J Gen Fam Med 20:4-8