Vorgeschlagene klinische Studien / Suggested clinical trials
Im Folgenden finden Sie Vorschläge für klinische Studien, die Sie mit dem CTrO-Editor modellieren könnten. Sie können jedoch auch eine Studie auswählen, die nicht in dieser Liste enthalten ist.
The following are suggestions of clinical trials that you can model with CTrO-Editor. However, you can also select a study not included in this list.
Type 2 Diabetes Mellitus:
Advancing insulin therapy in type 2 diabetes previously treated with glargine plus oral agents: prandial premixed (insulin lispro protamine suspension/lispro) versus basal/bolus (glargine/lispro) therapy. Rosenstock et al., 2008. PMID 17934150.
Improved meal-related insulin processing contributes to the enhancement of B-cell function by the DPP-4 inhibitor vildagliptin in patients with type 2 diabetes. Ahrén et al., 2007. PMID 17992639.
Mealtime 50/50 basal + prandial insulin analogue mixture with a basal insulin analogue, both plus metformin, in the achievement of target HbA1c and pre- and postprandial blood glucose levels in patients with type 2 diabetes: a multinational, 24-week, randomized, open-label, parallel-group comparison. Robbins et al., 2007. PMID 18158076.
A 52-week, multinational, open-label, parallel-group, noninferiority, treat-to-target trial comparing insulin detemir with insulin glargine in a basal-bolus regimen with mealtime insulin aspart in patients with type 2 diabetes. Hollander et al., 2008. PMID 19108786.
Efficacy and safety of sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes. Raz et al., 2008. PMID 18194595.
Glaucoma:
A comparison of the efficacy and tolerability of brimonidine and latanoprost in adults with open-angle glaucoma or ocular hypertension: a three-month, multicenter, randomized, double-masked, parallel-group trial. DuBiner et al., 2001. PMID 11813932.
Randomized clinical trial of latanoprost and unoprostone in patients with elevated intraocular pressure. Jampel et al., 2002. PMID 12470755.
Efficacy of the latanoprost versus timolol/dorzolamide combination therapy in patients with primary open angle glaucoma. Rismanchian et al., 2008. PMID 18327364.
An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/dorzolamide 2% in patients with elevated intraocular pressure. Hatanaka et al.,2008. PMID 19092465.
Efficacy and safety of fixed combinations of latanoprost/timolol and dorzolamide/timolol in open-angle glaucoma or ocular hypertension.
Miglior et al., 2009. PMID 20019759.
Atrial Fibrillation:
Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation. Patel et al., 2011. PMID 21830957.
Dabigatran versus Warfarin in Patients with Atrial Fibrillation. Connolly et al., 2009. PMID 19717844.
Apixaban versus Warfarin in Patients with Atrial Fibrillation. Granger et al., 2011. PMID 21870978.
Edoxaban versus Warfarin in Patients with Atrial Fibrillation. Giugliano et al., 2013. PMID 24251359.
Edoxaban versus enoxaparin–warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF): a randomised, open-label, phase 3b trial. Goette et al., 2016. PMID 27590218.