Embedded Files
Engineering TALE-linked deaminases to facilitate precision adenine base editing in mitochondrial DNA
Sung-Ik Cho*, Kayeong Lim*, Seongho Hong*, Jaesuk Lee, Annie Kim, Ji Min Lee, Young Geun Mok, Eugene Chung, Seunghun Han, Sang-Mi Cho, Jieun Kim, Sanghun Kim, Eun-Kyoung Kim, Ki-Hoan Nam, Yeji Oh, Minkyung Choi, Seonghyun Lee#, Hyunji Lee#, Jin-Soo Kim
Prime editing with genuine Cas9 nickases minimizes unwanted indels.
Jaesuk Lee*, Kayeong Lim*, Annie Kim, Young Geun Mok, Eugene Chung, Sung-Ik Cho, Ji Min Lee & Jin-Soo Kim
Nature Communications. 2023. doi.org/10.1038/s41467-023-37507-8
Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases
Sung-Ik Cho, Seonghyun Lee, Young Geun Mok, Kayeong Lim, Jaesuk Lee, Ji Min Lee, Eugene Chung and Jin-Soo Kim
Nuclear and mitochondrial DNA editing in human cells with zinc finger deaminases
Kayeong Lim*, Sung-Ik Cho* and Jin-Soo Kim
Nature Communications. 2022. doi.org/10.1038/s41467-022-27962-0
Base editing in human cells with monomeric DddA-TALE fusion deaminases
Young Geun Mok*, Ji Min Lee*, Eugene Chung*, Jaesuk Lee, Kayeong Lim, Sung-Ik Cho, and Jin- Soo Kim
Nature Communications. 2022. doi.org/10.1038/s41467-022-31745-y
Targeted A- to-G base editing of chloroplast DNA in plants
Young Geun Mok*, Sunghyun Hong*, Su-Ji Bae, Sung-Ik Cho, and Jin-Soo Kim
Adenine Base Editor Ribonucleoproteins Delivered by Lentivirus-Like Particles Show High On-Target Base Editing and Undetectable RNA Off-Target Activities
Pin Lyu*, Zuyan Lu*, Sung-Ik Cho, Manish Yadav, Kyung Whan Yoo, Anthony Atala, Jin-Soo Kim, and Baisong Lu
Genome-wide target specificity of CRISPR RNA-guided adenine base editors
Daesik Kim*, Da-eun Kim*, Gyeorae Lee, Sung-Ik Cho and Jin-Soo Kim
Nature Biotechnology. 2019. doi.org/10.1038/s41587-019-0050-1
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