The Varen VR Study is being conducted to explore biological markers of nicotine craving during a virtual reality (VR) experience in adults (22+) who smoke cigarettes daily. We are also testing to see if varenicline, an FDA approved medication for smoking cessation, affects these markers during the VR experience. Eligible participants will take the study medication (varenicline or placebo) for 17 days. This research study is sponsored by University of California, San Diego. 

• 22+ years of age

• Smoke cigarettes daily

• attend 3 in-person lab appointments (surveys, VR task)

• Take the study medication (varenicline or placebo) for 17 days.

• Fill out questionnaires through your phone for 17 days and complete one phone interview.