Publications

103. P. J. Brennan, R. R. E. Saunders, M. Spanou, M. Serafini, L. Sun, G. P. Heger, A. Konopacka, R. D. Beveridge, L. Gordon, S. B. Bunally, A. Saudemont, A. B. Benowitz, C. Martinez-Fleites, M. A. Queisser, H. An, C. M. Deane, M. M. Hann, L. L. Brayshaw, S. J. Conway. Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells. bioRxiv preprint, DOI: https://doi.org/10.1101/2024.03.15.585309.

102. C. A. Foster, D. Sneddon, L. Hacker, E. T. Sarson, M. Robertson, D. Sokolova, L. A. W. Martin, M. F. Allen, A. Khrapichev, K. A. Vincent, E. M. Hammond, S. J. Conway, S. Faulkner. LnDOTA Releasing Probes for Luminescence and Magnetic Resonance Imaging. Inorg. Chem., 2025, DOI: https://doi.org/10.1021/acs.inorgchem.5c00199.

101. X. Chao, T. G. Johnson, M-C. Temian, A. Docker, A. L. D. Wallabregue, A. Scott, S. J. Conway, M. J. Langton. Coupling photo-responsive transmembrane ion transport with transition metal catalysis. J. Am. Chem. Soc., 2024, 146, 4351.

100. G. Brodie and S. J. Conway. Disarming Gram-negative Bacteria in the Fight Against Antimicrobial Resistance. ACS Cent. Sci., 2023, 9, 2179.

99. M. Schiedel, D. McArdle, G. Padalino, A. K. N. Chan, H. Whiteland, M. McDonough, J. Forde-Thomas, M. Beckmann, R. Cookson, K. F. Hoffmann, S. J. Conway. Small molecule ligands of the BET-like bromodomain, SmBRD3, affect Schistosoma mansoni survival, oviposition, and development. J. Med. Chem., 2023, 66, 15801.

98. Ç. Tosun, M. Mallerman, A. L. D. Wallabregue, S. Phillips, C. M. Edwards, S. J. Conway, E. M. Hammond. Antibody-based imaging of bioreductive prodrug release in hypoxia. JACS Au, 2023, 3, 3237.

97. C. N. Russell, J. L. Carter, J. M. Borgia, J. Bush, F. Calderón, R. Gabarró, S. J. Conway, J. C. Mottram, A. J. Wilkinson, N. G. Jones. Bromodomain Factor 5 as Target for Antileishmanial Drug Discovery. ACS Infect. Dis., 2023, 9, 2340.

96. A. M. Thomas, M. Serafini, E. K. Grant, E. A. J. Coombs, J. P. Bluck, M. Schiedel, M. A. McDonough, J. K. Reynolds, B. Lee, M. Platt, V. Sharlandjieva, P. C. Biggin, F. Duarte, T. A. Milne, J. T. Bush, S. J. Conway. Mutate and Conjugate: A Method to Enable Rapid In Cell Target Validation. ACS Chem. Biol., 2023, 18, 2405.

95. A. L. D. Wallabregue, H. Bolland, S. Faulkner, E. M. Hammond, S. J. Conway. Two color imaging of different hypoxia levels in cancer cells. J. Am. Chem. Soc., 2023, 145, 2572.

94. A. R. Sekirnik, J. K. Reynolds, L. See, J. P. Bluck, A. R. Scorah, C. Tallant, B. Lee, K. B. Leszczynska, R. L. Grimley, R. I. Storer, M. Malattia, S. Crespillo, S. Caria, S. Duclos, E. M. Hammond, S. Knapp, G. M. Morris, F. Duarte, P. C. Biggin, S. J. Conway. Identification of histone peptide binding specificity and small molecule ligands for the TRIM33 bromodomain. ACS Chem. Biol., 2022, 17, 2753.

93. C. C. Aldrich, F. Calderón, S. J. Conway, C. He, J. M. Hooker, D. M. Huryn, C. W. Lindsley, D. C. Liotta, C. E. Müller.  Virtual Special Issue: Epigenetics 2022. ACS Infect. Dis., 2022, 8, 1975.

92. S. J. Conway, A. Kawamura, T. M. Marr, F. Platt, A. J. Russell. Increasing Diversity in Admissions to Postgraduate Study. J. Med. Chem., 2022, 65, 5867.

91. S. J. Booker, S. J. Conway, A. Lavasavifar. Welcome to ACS Bio & Med Chem Au. ACS Bio & Med Chem Au, 2021, 1, 1.

90. K. S. Troelsen, E. D. D. Calder, A. Skwarska, E. M. Hammond, S. J. Conway, Zap-Pano: a photocaged pro-drug of the KDAC inhibitor panobinostat. ChemMedChem, 2021, 16, 3691.

89.  M. L. Bolognesi and S. J. Conway, Celebrating the Chemistry of Gunda Georg and Shaomeng Wang. J. Med. Chem., 2021, 64, 17541.

88. M. Brand, J. Clayton, M. Moroglu, M. Schiedel, S. Picaud, J. P. Bluck, A. Skwarska, A. K. N. Chan, C. M. C. Laurin, A. R. Scorah, K. F. L. See, T. P. C. Rooney, O. Fedorov, G. Perell, W. A. Cortopassi, K. E. Christensen, R. I. Cooper, R. S. Paton, W. C. K. Pomerantz, P. C. Biggin, E. M. Hammond, P. Filippakopoulos, S. J. Conway. Controlling intramolecular interactions to develop selective, high-affinity ligands for the CREBBP bromodomain. J. Med. Chem., 2021, 64, 10102.

87. C. W. Lindsley, J. Barrow, K. Chibale, M. L. Bolognesi, S. J. Conway, W. Denny, K. Ding, S. Laufer, L. Lai, H. Liu, N. Neamati, T. Suzuki, N. Meanwell, W. Young. Simplifying the submissions requirements for the Journal of Medicinal Chemistry. J. Med. Chem., 2021, 64, 7877.

86. N. R. Flynn, M. D. Ward, M. A. Schleiff, C. M. C. Laurin, S. J. Conway, G. Boysen, S. J. Swamidass, G. P. Miller. Bioactivation of isoxazole-containing bromodomain and extra terminal domain (BET) inhibitors. Metabolites, 2021, 11, 390.

85. A. Skwarska, E. D. D. Calder, I. N. Mistry, D. Sneddon, S. J. Conway, E. M. Hammond. Development and pre-clinical testing of a novel hypoxia-activated pan KDAC inhibitor. Cell Chem. Biol., 2021, 28, 1258.

84. N. Favalli, G. Bassi, C. Pellegrino, J. Millul, R. De Luca, S. Cazzamalli, S. Yang, A. Trenner, N. Mozzafari, R. Myburgh, M. Moroglu, S. J. Conway, A. Sartori, M. M. Manz, R. A. Lerner, P. Vogt, J. Scheuermann, D. Neri. Stereo- and regio-defined DNA-encoded chemical libraries enable efficient ligand discovery for conditional CAR-T cell activation and for tumor targeting. Nat. Chem., 2021, 13, 540.

83. G. P. Miller, M. Schleiff, N. Flynn, M. Ward, C. Laurin, S. J. Conway, S. Swamidass. Novel bioactivation of isoxazole-containing bromodomain and extra terminal domain (BET) inhibitors. FASEB J., 2021, 35, DOI: 10.1096/fasebj.2021.35.S1.04681.

82. A. M. Joffrin, A. M. Saunders, D. Barneda, V. Flemington, A. L. Thompson, H. J. Sanganee, S. J. Conway. Enantioselective synthesis of isotope-enriched phosphatidylinositol-4- and 5-phosphate probes. Chem. Sci., 2021, 12, 2549.

81. C. M. C. Laurin, J. P. Bluck, A. K. Chan, M. Keller, A. Boczek, L. E. Jennings, A. R. Scorah, K. F. L. See, D. S. Hewings, F. Woodhouse, J. K. Reynolds M. Schiedel, P. G. Humphreys, P. C. Biggin, S. J. Conway. Fragment-based identification of ligands for bromodomain-containing factor 3 of Trypanosoma cruzi. ACS Infect. Dis., 2021, 7, 2238.

80. S. J. Conway, P. Arimondo, C. Arrowsmith, J. Jin, C. Luo, N. Meanwell, W. Young, G. Georg, S. Wang. Epigenetics 2.0: Special Issue on Epigenetics – Call for Papers. J. Med. Chem., 2020, 63, 12129.

79. E. Bowler, A. Skwarska, J. D. Wilson, S. Ramachandran, H. Bolland, A. Easton, M-S. Hwang, K. B. Leszczynska, S. J. Conway, E. M. Hammond. Pharmacological inhibition of ATR can lead to a blockage in autophagy. iScience, 2020, 101668.