If you are not taking additional steps to make your math equations accessible, they are extremely inaccessible to disabled students. Your goal is to support students with learning disabilities. If you are adding special characters without LaTeX or another software, a screen reader will read the equation incorrectly. There are many tools to help you make your equations accessible.
Working in STEM? You should take the time to review VLC's Accessible Math Guide. It is an invaluable resource.
If you're not using a math notation format (e.g., LaTex, MathML, or ASCII Math) or a program that generates that output (e.g., EquatIO), your math is inaccessible.
It is currently impossible to make math accessible in PDF format. PDFs should not be used for equations.
If the program you are using has a math editor, you should always use it to input the math into documents (e.g., Microsoft's Insert Equation function)
Accessibility Strategies for Mathematics (Achieve The Core)
Are there Commercial Products Designed to Make Math Accessible to Students with Disabilities? (Washington Do-It Center)
How Can I Create Math and Science Documents that are Accessible to Students with Visual Impairments? (Washington Do-It Center)
Make Mathematics Instruction Accessible and Engaging for All Students (Inclusive Schools Network)
STEM Concept (Mira Costa College)
Where can I find Tips on Making Math Accessible to Students with Disabilities (Washington Do-It Center)