Research

Biophysics is a field of study that aims to understand biological phenomena using the principles and tools of physics. Every living organisms must be following the laws of physics, however, due to their complexity, our understanding on biological systems is still limited.

Our research group focuses on the studies of biological molecules such as proteins and nucleotides. Biological complexes, structured ensembles of proteins and nucleic acids, perform many vital cellular functions and dysfunctions of those result in severe diseases. In order to understand diseases and develop treatments, the functional mechanisms of these biological complexes need to be elucidated. A crucial step in this process is the characterization of the structures and dynamics of these complexes. We use computational techniques, often in collaboration with experimental groups, to study important biological systems.

We have collaborations with experimental groups in the field of X-ray crystallography, Cryo-Electron Micoscopy, X-ray Free Electron laser and Atomic Force Microscopy either to study specific biolical systems or to develop computational tools to intepret and integrate multiple type of experimental data.