Selected Publications

• • • • Bhardwaj K, Roy A, Guha L, Kumar H. Evaluating the Role of Lin-11, Isl-1, and Mec-3 Kinases in Dopaminergic Neurodegeneration in a Subacute 1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine Model of Parkinson’s Disease. ACS Pharmacology & Translational Science 2024. 

      • Roy A, Sen S, Das R, Shard A, Kumar H. Modulation of the LIMK Pathway by Myricetin: A Protective Strategy Against Neurological Impairments in Spinal Cord Injury. Neurospine 2024.

      • Roy A, Pathak Z, Kumar H. Investigating LIM (Lin-11, Isl-1, and Mec-3) Kinases and Their Correlation with Pathological Events and Microtubule Dynamics in an Experimental Model of Spinal Cord Injury in Rats. ACS Pharmacology & Translational Science 2024. 

      • Pathak Z, Jadav T, Roy A, Chopra M, Singh N, Sengupta P, Kumar H. Maresin-1 prevents blood-spinal cord barrier disruption associated with TRPV4 elevation in the experimental model of spinal cord injury. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids 2023. 

      • Dolma S, Adhikari K, Mamidi T, Roy A, Pathak Z, Kumar H: Ethamsylate attenuates mutilated secondary pathogenesis and exhibits a neuroprotective role in experimental model of spinal cord injury. Neuroscience 2022. 

      • Adhikari K, Dolma S, Mamidi T, Roy A, Pathak Z, Kumar H: Tomographic Imaging and Correlation to Quantify Vascular and Inflammatory Changes in an Experimental Spinal Cord Injury. ACS Chemical Neuroscience 2021, 12:3864-3872.

      • Lim S, An SB, Jung M, Joshi HP, Kumar H, Kim C, Song SY, Lee JR, Kang M, Han I: Local delivery of senolytic drug inhibits intervertebral disc degeneration and restores intervertebral disc structure. Advanced Healthcare Materials 2021:2101483. 

      • Kim J, Joshi HP, Sheen SH, Kim KT, Kyung JW, Choi H, Kim YW, Kwon SY, Roh EJ, Choi UY, Sohn S, Kim YH, Park CK, Kumar H, Han IB.: Resolvin D3 promotes inflammatory resolution, neuroprotection, and functional recovery after spinal cord injury. Molecular Neurobiology 2021, 58:424-438.

      • Kumar H, Lim CS, Choi H, Joshi HP, Kim K-T, Kim YH, Park C-K, Kim HM, Han I-B: Elevated TRPV4 levels contribute to endothelial damage and scarring in experimental spinal cord injury. Journal of Neuroscience 2020, 40:1943-1955. 

      • Muttigi MS, Kim BJ, Kumar H, Park S, Choi UY, Han I, Park H, Lee S-H: Efficacy of matrilin-3-primed adipose-derived mesenchymal stem cell spheroids in a rabbit model of disc degeneration. Stem cell research & therapy 2020, 11:1-12. 

      • Kim J, Joshi HP, Kim K-T, Kim YY, Yeo K, Choi H, Kim YW, Choi U-Y, Kumar H, Sohn S: Combined Treatment with Fasudil and Menthol Improves Functional Recovery in Rat Spinal Cord Injury Model. Biomedicines 2020, 8:258.

      • Joshi HP, Kumar H, Choi UY, Lim YC, Choi H, Kim J, Kyung JW, Sohn S, Kim K-T, Kim J-K: CORM-2-solid lipid nanoparticles maintain integrity of blood-spinal cord barrier after spinal cord injury in rats. Molecular neurobiology 2020, 57:2671-2689. 

      • Kumar H, Choi H, Jo M-J, Joshi HP, Muttigi M, Bonanomi D, Kim SB, Ban E, Kim A, Lee S-H: Neutrophil elastase inhibition effectively rescued angiopoietin-1 decrease and inhibits glial scar after spinal cord injury. Acta neuropathologica communications 2018, 6:1-18. 

      • Muttigi MS, Kim BJ, Choi B, Yoshie A, Kumar H, Han I, Park H, Lee SH: Matrilin‐3 codelivery with adipose‐derived mesenchymal stem cells promotes articular cartilage regeneration in a rat osteochondral defect model. Journal of tissue engineering and regenerative medicine 2018, 12:667-675. 

      • Kumar H, Jo M-J, Choi H, Muttigi MS, Shon S, Kim B-J, Lee S-H, Han I-B: Matrix metalloproteinase-8 inhibition prevents disruption of blood–spinal cord barrier and attenuates inflammation in rat model of spinal cord injury. Molecular neurobiology 2018, 55:2577-2590. 

      • Kim HY, Kumar H, Jo M-J, Kim J, Yoon J-K, Lee J-R, Kang M, Choo YW, Song SY, Kwon SP: Therapeutic efficacy-potentiated and diseased organ-targeting nanovesicles derived from mesenchymal stem cells for spinal cord injury treatment. Nano letters 2018, 18:4965-4975. 

      • Kim HJ, Lim CS, Lee HW, Lee HS, Um YJ, Kumar H, Han I, Kim HM: A ratiometric two-photon probe for Ca2+ in live tissues and its application to spinal cord injury model. Biomaterials 2017, 141:251-259 

      • Kumar H, Ha D, Lee E, Park J, Shim J, Ahn T, Kim K, Ropper A, Sohn S, Kim C: Safety and tolerability of intradiscal implantation of combined autologous adipose-derived mesenchymal stem cells and hyaluronic acid in patients with chronic discogenic low back pain: 1-year follow-up of a phase I study. Stem Cell Research & Therapy 2017, 8. 

      • Ahn J, Kumar H, Cha B-H, Park S, Arai Y, Han I, Park SG, Lee S-H: AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal. Cell Death & Disease 2016, 7.

      • Kumar H, Kim I-S, More SV, Kim B-W, Choi D-K: Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases. Natural product reports 2014, 31:109-139. 

      • Kumar H, Lim J-H, Kim I-S, Choi D-K: Differential regulation of HIF-3α in LPS-induced BV-2 microglial cells: Comparison and characterization with HIF-1α. Brain research 2015:33-41.

      • Lee J-R, Kyung JW, Kumar H, Kwon SP, Song SY, Han I-B, Kim B-S: Targeted delivery of mesenchymal stem cell-derived nanovesicles for spinal cord injury treatment. International journal of molecular sciences 2020, 21:4185.

      • Lim JJ, Shin DA, Jeon YJ, Kumar H, Sohn S, Min HS, Lee JB, Kuh SU, Kim KN, Kim JO: Association of miR-146a, miR-149, miR-196a2, and miR-499 polymorphisms with ossification of the posterior longitudinal ligament of the cervical spine. PLoS One 2016, 11:e0159756.

      • Gullapalli S, Amrutkar D, Gupta S, Kandadi MR, Kumar H, Gandhi M, Karande V, Narayanan S: Characterization of active and inactive states of CB1 receptor and the differential binding state modulation by cannabinoid agonists, antagonists and inverse agonists. Neuropharmacology 2010, 58:1215-1219.

For complete list of publications follow the link:- https://scholar.google.com/citations?user=VfM5Yh0AAAAJ&hl=en