* Equal contribution; # co-corresponding.
2021
Mulas C*, Chaigne A*, Smith A and Chalut KJ (2021). Cell State Transitions: Definitions and Challenges. Development 148, dev199950
Posfai E, Lanner F, Mulas C and Leitch HG (2021). All models are wrong, but some are useful: establishing standards for stem cell-based embryo models. Stem Cell Reports, 16(5), 1117-1141.
Labouesse C, Tan BX, Agley C, Hofer M, Winkel A, Stirparo GG, Stuart H, Verstreken C, Mulas C, Mansfield W, Bertone P, Franze K, Silva J and Chalut K (2021). StemBond hydrogels control the mechanical microenvironment for pluripotent stem cells. Nature Communications, 12, 6132.
2020
Mulas C*#, Hodgson AC*, Kohler TN, Agley CC, Humphreys P, Kleine-Bruggeney H, Hollfelder F, Smith A and Chalut KJ# (2020). Microfluidic platform for 3D cell culture with live imaging and clone retrieval. Lab on a Chip 20(14), 2580–2591. More info here.
2019
Mulas C#, Kalkan T, von Meyenn F, Leitch HG, Nichols J, Smith A# (2019). Defined conditions for propagation and manipulation of mouse embryonic stem cells. Development, 146(6), dev173146.
Kalkan T, Bornelöv S*, Mulas C*, Diamanti E, Lohoff T, Ralser M, Middelkamp S, Lombard P, Nichols J, Smith A(2019). Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency. Cell Stem Cell, 24(5), 785-801.
Pijuan-Sala B, Griffiths JA, Guibentif C, Hiscock TW, Jawaid W, Calero-Nieto FJ, Mulas C, Ibarra-Soria X, Tyser RCV, Ho DLL, Reik W, Srinivas S, Simons BD, Nichols J, Marioni JC, Göttgens B, (2019). A single-cell molecular map of mouse gastrulation and early organogenesis. Nature, 566, 490–495.
2018
Mulas C*, Chia G*, Jones KA, Hodgson AC, Stirparo GG, Nichols J, (2018). Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo. Development, 145(12), dev159103–20. More info here.
Nett IR*, Mulas C*, Gatto L, Lilley KS, Smith A, (2018). Negative feedback via RSK modulates Erk-dependent progression from naïve pluripotency. EMBO Reports, e45642–15. More info here.
Kleine‐Brüggeney H, Van Vliet LD, Mulas C, Gielen G, Agley CC, Silva JCR, Smith A, Chalut K, Hollfelder F, (2018). Long‐Term Perfusion Culture of Monoclonal Embryonic Stem Cells in 3D Hydrogel Beads for Continuous Optical Analysis of Differentiation. Small, 5, 1804576.
Ibarra-Soria X, Jawaid W, Pijuan-Sala B, Ladopoulos V, Scialdone A, Jörg DJ, Tyser RCV, Calero-Nieto FJ, Mulas C, Nichols J, Vallier L, Srinivas S, Simons BD, Göttgens B, Marioni JC, (2018). Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation. Nature Cell Biology, 20, 127–134.
2017
Mulas C, Kalkan T, Smith A, (2017). Nodal secures formative pluripotency upon embryonic stem cell progression from the naïve state. Stem Cell Reports, 9, 77–91. More info here.
Kalkan T, Olova N, Roode M, Mulas C, Lee HJ, Nett I, Marks H, Walker R, Stunnenberg HG, Lilley KS, Nichols J, Reik W, Bertone P, Smith A, (2017). Tracking the embryonic stem cell transition from ground state pluripotency. Development,144(7), dev.142711–56.
Mohammed H, Hernando-Herraez I, Savino A, Scialdone A, Macaulay I, Mulas C, Chandra T, Voet T, Dean W, Nichols J, Marioni JC, Reik W, (2017). Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation. Cell Reports, 20, 1215–1228.
2014
Le Bin,GC, Munoz-Descalzo S, Kurowski A, Leitch HG, Lou X, Mansfield W, Etienne-Dumeau C, Grabole N, Mulas C, Niwa H, Hadjantonakis AK and Nichols J, (2014). Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst. Development, 141(5), pp.1001–1010.
2013
Leitch HG, Nichols J, Humphreys P, Mulas C, Martello G, Lee C, Jones K, Surani, MA and Smith A, (2013). Rebuilding pluripotency from primordial germ cells. Stem Cell Reports, 1(1), pp. 66-78.