Publications

Saha S, Balaji AK, Meel S, Notani D and Sengupta K (2025) Fibrillarin regulates Epithelial Integrity via EZH2-mediated modulation of Scribble Expression, Cell Reports, 44, 12, 116608. 

Nair A, Khanna J, Kler J, Ragesh R, Sengupta K (2025) Nuclear envelope and chromatin choreography direct cellular differentiation. Nucleus. Dec;16(1):2449520.

Datta D, Navalkar A, Sakunthala A, Paul A, Patel K, Masurkar S, Gadhe L, Manna S, Bhattacharyya A, Sengupta S, Poudyal M, Devi J, Sawner AS, Kadu P, Shaw R, Pandey S, Mukherjee S, Gahlot N, Sengupta K, Maji SK. (2024) Nucleo-cytoplasmic environment modulates spatiotemporal p53 phase separation. Sci Adv. 10(50).

Adhikari S, Singh V, Nandi S, Ghosal M, Raj NS, Khanna J, Bhattacharya A, Kabiraj A, Mondal A, Vasudevan M, Senapati D, Roy H, Sengupta K, Notani D, Das C. (2024) UBR7 in concert with EZH2 inhibits the TGF-β signaling leading to extracellular matrix remodeling. Cell Rep. 43(7):114394.

Patil S, Deshpande S and Sengupta K (2023) Nuclear envelope protein LBR protects the genome from chromosomal instability and tumorigenesis. Human Molecular Genetics, 32, 5, 1, 745–763, Featured in Department of Science & Technology (DST), Hindustan Times.

Balaji AK*, Saha S*, Deshpande S*, Poola D and Sengupta K (2022) Nuclear envelope, chromatin organizers, histones, and DNA: The many Achilles heels exploited across cancers. Front. Cell Dev. Biol. Sec. Nuclear Organization and Dynamics (Provisionally accepted), doi: 10.3389/fcell.2022.1068347 (*equal contribution). 

Sakunthala A, Datta D, Navalkar A, Gadhe L, Kadu P, Patel K, Mehra S, Kumar R, Chatterjee D, Devi J, Sengupta K, Padinhateeri R, Maji SK (2022) Direct Demonstration of Seed Size-Dependent α-Synuclein Amyloid Amplification. J Phys Chem Lett. 2022;13(28):6427-6438

Labade AS*, Salvi A*, Kar S, Karmodiya K and Sengupta K (2021) Nup93 and CTCF modulate spatiotemporal dynamics and function of the HOXA gene locus during differentiation , J Cell Sci. *Equal Contribution, First person – Ajay Labade and Adwait Salvi

Patil,  S.  Jahagirdar, S, Khot M,  and  Sengupta K (2021) Studying  the  role  of  chromosomal instability (CIN) in GI cancers using patient-derived organoids, Journal of Molecular Biology. 

Shah R, Sharma A, Kelkar A, Sengupta K, Galande S (2021). A novel cis regulatory element regulates human XIST in CTCF-dependent manner. Mol Cell Biol, 41, 8. 

Patil, S and Sengupta, K. (2021) Role of A‐ and B‐type lamins in nuclear structure‐function relationships, Biol. Cell, 1-16. 

Khot M, Sreekumar D, Jahagirdar S1, Kulkarni A1, Hari K, Faseela EE, Sabarinathan R, Jolly MK, Sengupta K (2020). Twist1 induces chromosomal instability (CIN) in colorectal cancer cells.  Hum. Mol. Genet. Profiled here: Fellow's research: To CIN or not to CIN - a Twist in the tale,   facebook

Pradhan R, Jayakrishnan MN and Sengupta K (2020) Lamin A/C modulates spatial organization and function of the Hsp70       gene locus via Nuclear Myosin I (NM1). Journal of Cell Science, 133. Featured as a Research highlight in Journal of Cell Sciences. First person - Roopali Pradhan

Pradhan R and Sengupta K (2019) Imaging chromosome territory and gene loci positions in cells grown on softer matrices. Methods in Mol. Biol. 

Ranade D, Pradhan R, Jayakrishnan MN, Hegde S and Sengupta K (2019) Lamin A/C and Emerin depletion impacts chromatin organization and dynamics in the interphase nucleus BMC, Molecular & Cell Biology, 20(1):11 

Sengupta A, Joshi G, Pawar S and Sengupta K (2018) Nucleolin modulates compartmentalization and dynamics of histone2B-ECFP in the nucleolus. Nucleus;9(1).  

Sengupta K. Genome 3D-architecture: its plasticity in relation to function (2018) J. Biosciences. 43,2. 

Pradhan R, Ranade D, Sengupta K (2018) Emerin modulates spatial organization of chromosome territories in cells on softer matrices. Nucleic Acids Res. 

Sen Gupta A and Sengupta K (2017) Lamin B2 Modulates Nucleolar Morphology, Dynamics, and Function. Mol Cell Biol. Nov 28;37(24). Opinion comment "The many things that Lamin B2 can do" by R.Prasad - The Hindu, Jan 30, 2018. 

Labade AS, Karmodiya K, Sengupta K (2016) HOXA repression is mediated by nucleoporin Nup93 assisted by its interactors Nup188 and Nup205. Epigenetics Chromatin. Dec 3; 9:54.

Ranade D, Koul S, Thompson J, Prasad KB, Sengupta K (2017). Chromosomal aneuploidies induced upon Lamin B2 depletion are mislocalized in the interphase nucleus. Chromosoma. 126(2):223-244. 

Khodade VS, Kulkarni A, Gupta AS, Sengupta K and Chakrapani H (2016) A Small Molecule for Controlled Generation of Peroxynitrite. Org Lett. 18(6):1274-7.  

Malwal R, S, Labade A, Andhalkar, SA, Sengupta K and Chakrapani H (2014) A highly selective sulfinate ester probe for thiol bioimaging. Chem. Commun., 50, 11533. 

Ranade, D. and Sengupta, K. (2013). Nuclear organization of cancer cells. In Recent  Trends in Gene expression, Mandal, S.S. (Ed.) pp. 133-146, Nova Science Publishers.     

Sharma, K., Iyer, A., Sengupta, K. and Chakrapani, H. (2013). INDQ/NO,  bioreductively-activated nitric oxide prodrug. Organic Letters, 15:2636-2639.

Sharma, K., Sengupta, K. and Chakrapani, H. (2013). Nitroreductase-activated nitric oxide (NO) prodrugs. Bioorganic & Medicinal Chemistry Letters, 23:5964-5967

Paranjape AN, Mandal T, Mukherjee G, Kumar MV, Sengupta K, Rangarajan A (2011) Introduction of SV40ER and hTERT into mammospheres generates breast cancer cells with stem cell properties. Oncogene, 31,1896-1909

Fishler T, Li YY, Wang RH, Kim HS, Sengupta K, Vassilopoulos A, Lahusen T, Xu X, Lee MH, Liu Q, Elledge SJ, Ried T, Deng CX (2010) Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53. Oncogene, 29(28): 4007-17 

Gertz EM, Sengupta K, Difilippantonio MJ, Ried T and Schaffer AA (2009) Evaluating annotations of an Agilent expression chip suggests that many features cannot be interpreted. BMC Genomics. 10:566

Wang RH., Sengupta K, Cuiling Li, Kim SH, Cao L, Xiao C, Kim S, Xiaoling XX, Zheng Y, Chilton B, Rong J, Zheng ZH, Ettore A, Xin WW, Ried T & Deng CX (2008) Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell, 14: 312-323

Sengupta K., Camps J, Mathew P, Stapleton L, Nguyen QT, Difilippantonio MJ & Ried T (2008) Position of human chromosomes is conserved in mouse nuclei indicating a species-independent mechanism for maintaining genome organization. Chromosoma, 117:499–509 

Sengupta K., Upender M, Stapleton L, Nguyen QT, Wincovitch S, Garfield S, Difilippantonio MJ & Ried T (2007) Artificially introduced chromosomes assume a conserved, non-random position in nuclei of colon cancer cells. PLoS One, 2:e199 

Soutoglou E., Dorn JF, Sengupta K, Jasin M, Nussenzweig A, Ried T, Danuser G, & Misteli T (2007) Positional stability of single double strand breaks in living mammalian cells. Nat. Cell. Biol, 9: 675-682 

Suseendranathan K.,* Sengupta K*, Rikhy R, D’Souza J, Kokkanti M, Kulkarni G M,  Kamdar R, Changede R, Sinha R, Subramanian L, Singh K, Rodrigues V & Rao B.J (2007) Expression pattern of Drosophila Translin and behavioral analyses of the mutant. European Journal of Cell Biology 86: 173-186 (*equal contribution) 

Mazumdar M., Lee JH, Sengupta K, Ried T, Rane S & Misteli T. (2006) Tumor formation via loss of a molecular motor protein. Curr Biol.16: 1559-1564 

Sengupta K., Kamdar R, D’Souza J, Mustafi S & Rao B.J (2006) GTP induced conformational changes in translin: a comparison between Human and Drosophila proteins. Biochemistry, 45: 861-870. 

Rao B.J. & Sengupta K (2003) Human Y-chromosome: a hall of mirrors. J. Biosciences. 28: 533- 534

Sengupta K & Rao B.J (2002) Translin binding to DNA: recruitment through DNA ends and consequent conformational transitions Biochemistry, 41: 15315-15326