Selected Publications

31. S. Mohammad, K. Amar, F. Chowdhury, "Hybrid AI models allow label-free identification and classification of pancreatic tumor repopulating cell population," Biochemical and Biophysical Research Communications, 677, 126-131, 2023.

30. K. Amar, S. Saha, A. Debnath,C.H. Weng, A. Roy, K. Y. Han, and F. Chowdhury "Reduced Cell–ECM Interactions in the EpiSC Colony Center Cause Heterogeneous Differentiation," Cells, 12(2), 326, 2023.

29.  F. K. Protick, S. K. Amit, K. Amar, S. D. Nath, R. Akand, V. A. Davis, S. Nilufar, F. Chowdhury, "Additive Manufacturing of Viscoelastic Polyacrylamide Substrates for Mechanosensing Studies," ACS Omega,  7, 24384–24395, 2022.

28. F. Chowdhury, B. Huang, N. Wang, "Forces in stem cells and cancer stem cells," Cells & Development, 203776, 2022.

27. R. Ahmed, T. Zaman, F. Chowdhury, F. Mraiche, M. Tariq, I. S. Ahmad, A. Hasan, "Single-Cell RNA Sequencing with Spatial Transcriptomics of Cancer Tissues" International Journal of Molecular Sciences, 23 (6), 3042, 2022.

26. M Sharifi, Q Bai, MMN Babadaei, F. Chowdhury, M Hasan, ..., "3D bioprinting of engineered breast cancer constructs for personalized and targeted cancer therapy," Journal of Controlled Release, 333, 91-106, 2021.

25. F. Chowdhury, B Huang, N Wang, "Cytoskeletal prestress: the cellular hallmark in mechanobiology and mechanomedicine," Cytoskeleton, 78 (6), 249-276, 2021.

24. B.Talluri, K. Amar, M. Saul, T. Shireen, V. Konjufca, J. Ma, T. Ha, F. Chowdhury, "COL2A1 Is a Novel Biomarker of Melanoma Tumor Repopulating Cells ,"  Biomedicines,  8(9), 360, 2020.

23. C. T. Mandrell, T. E. Holland, J. F. Wheeler, S. Esmaeili, K. Amar, F. Chowdhury, P. Sivakumar,  "Machine Learning Approach to Raman Spectrum Analysis of MIA PaCa-2 Pancreatic Cancer Tumor Repopulating Cells for Classification and Feature Analysis," Life, 10 (9), 181, 2020.

22. K. Amar, I. I. Suni, F. Chowdhury, "A quartz crystal microbalance based study reveals living cell loading rate via αvβ3 integrins," Biochemical and Biophysical Research Communications, 524 (4), 1051-1056, 2020.

21. F. Chowdhury, S. Doğanay, B.J. Leslie, R. Singh, K. Amar, B. Talluri, S. Park, N. Wang, T. Ha, "Cdc42-dependent modulation of rigidity sensing and cell spreading in tumor repopulating cells," Biochemical and Biophysical Research Communications, 500 (3), 557-563, 2018.

20. A Barui, F Chowdhury, A Pandit, P Datta, "Rerouting Mesenchymal Stem Cell Trajectory towards Epithelial Lineage by Engineering Cellular Niche," Biomaterials, 156, 28-44, 2018. 

19. I. Muhamed, F. Chowdhury, V. Maruthamuthu, "Biophysical Tools to Study Cellular Mechanotransduction," Bioengineering 4(1),   12, 2017.

18. Q. Ahmad, K. Amar, F. Chowdhury, P. Kohli, M. Shamsi, "Wax Patterned Microwells for Stem Cell Fate Study," RSC Advances 6, 104919-104924, 2016.

17. F. Chowdhury, I.T.S. Li, T.T.M. Ngo, B.J. Leslie, B.C. Kim, J.E. Sokoloski, E. Weiland, X. Wang, Y.R. Chemla, T.M. Lohman, and T. Ha, "Defining single molecular forces required for Notch activation using nano yoyo," Nano Letters 16 (6), 3892–3897, 2016. (link)

16. X. Wang, Z. Rahil, I.T.S. Li, F. Chowdhury, D. Leckband, Y. Chemla, T. Ha, "Constructing modular and universal single molecule tension sensor using protein G to study mechanosensitive receptors," Scientific Reports, 6, 21584, 2016. (link)

15. X.Wang, J. Sun, Q. Xu, F. Chowdhury, M. Roein-Peikar, Y. Wang, T. Ha, "Integrin Molecular Tension within Motile Focal Adhesions," Biophysical Journal 109 (11), 2259-2267, 2015. (link) 

14. F. Chowdhury, S. Doganay, B. Leslie, R. Singh, S. Lee, N. Wang, T. Ha, "Single molecular force across single integrins dictates cell spreading," Integrative Biology 7 (10), 1265-71, 2015. (link)

13. Y. Tan, A. Tajik, J. Chen, Q. Jia, F. Chowdhury, L. Wang, J. Chen, S. Zhang, Y. Hong, H. Yi, D. C. Wu, Y. Zhang, F. Wei, Y.C. Poh, J. Seong, R. Singh, L.J. Lin, S. Doganay, Y. Li, H. Jia, T. Ha, Y. Wang, B. Huang, N. Wang, "Matrix softness regulates plasticity of tumor-repopulating cells via H3K9 demethylation and Sox2 expression,” Nature Communications 5: 4619, 2014.(link)

12. Y.C. Poh, SP Shevtsov, F. Chowdhury, D. C. Wu, S. Na, M. Dundr, N. Wang, "Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells," Nature communications 415(2):866-75, 2012. (link)

11. Y. Uda, Y.C. Poh, F. Chowdhury, D. C. Wu, T. S. Tanaka, M. Sato, N. Wang, "Force via integrins but not E-cadherin decreases Oct3/4 expression in embryonic stem cells,” Biochemical and Biophysical Research Communications,415(2):396-400, 2011. (link)

10. D. Li, J. Zhou, F. Chowdhury, J. Cheng, N. Wang, F. Wang, "Role of mechanical factors in fate decisions of stem cells," Regenerative Medicine 6(2): 229-240, 2011. (link)

9. F. Chowdhury, Y. Li, Y.C. Poh, T. Tamaki, N. Wang, T. S. Tanaka, "Soft substrates promote homogeneous self-renewal of embryonic stem cells via downregulating cell-matrix tractions," PLoS ONE 5(12): e15655, 2010. (link) 

[Media coverage: University of Illinois News Bureau (Dec. 15, 2010), Science Daily (Chevy Chase, MD, Dec. 15, 2010), e! Science News (Quebec City, Dec. 15, 2010), Genetic Engineering & Biotechnology (New Rochelle, NY, Dec. 15, 2010), PhysOrg (Douglas, Isle of Man, Dec. 15, 2010), R&D Magazine (Rockaway, NJ, Dec. 15, 2010) and several other scientific magazines featured a news article on this work.] 

8. F. Chowdhury*, Y.C. Poh*, T. S. Tanaka, N. Wang, "Embryonic stem cells do not stiffen on rigid substrates," Biophysical Journal 99: L19-L21, 2010. (* co-first author) (link)

7. M. Shin, Y. He, D. Li, S. Na, F. Chowdhury, Y. C. Poh, O. Collin, P. Su, P. Lanerolle, M Shwartz, N. Wang, F. Wang, "Spatiotemporal organization, regulation and functions of tractions during neutrophil chemotaxis," Blood 116: 3297-3310, 2010. (link)

6. F. Chowdhury, S. Na, D. Li, Y. C. Poh, T. S. Tanaka, F. Wang, and N. Wang, "Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells," Nature Materials 9: 82-8, 2010. (link)

[Media coverage: Highlighted in Nature Materials: News and Views (Jan 1, 2010), University of Illinois News Bureau (Oct 19, 2009) and several other science magazines including The Scientist. Post publication peer review can also be found in F1000 Biology.] 

5. Y. C. Poh, S. Na, F. Chowdhury, M. Ouyoung, Y. Wang, and N. Wang, "Rapid activation of Rac GTPase in living cells by force is independent of Src," PLoS ONE 4: e7886, 2009. (link)

4. F. Chowdhury*, S. Na*, B. Tay*, M. Ouyang, M. Gregor, Y. Wang, G. Wiche, and N. Wang, "Plectin contributes to mechanical properties of living cells," American Journal of Physiology Cell Physiology 296: C868-77, 2009. (* co-first author) (link)

3. F. Chowdhury, S. Na, O. Collin, B. Tay, F. Li, T. Tanaka, D. E. Leckband, and N. Wang, "Is cell rheology governed by nonequilibrium-to-equilibrium transition of noncovalent bonds?" Biophysical Journal 95: 5719-5727, 2008. (link)

2. O. Collin, S. Na, F. Chowdhury, M. Hong, M. Shin, F. Wang, and N. Wang. "Self-organized podosomes are dynamic mechanosensors," Current Biology 18, 1288-1294, 2008. (link)

1. S. Na, O. Collin, F. Chowdhury, B. Tay, M. Ouyang, Y. Wang, N. Wang, "Rapid signal transduction in living cells is a unique feature of mechanotransduction," Proceedings of the National Academy of Sciences of the U.S.A. 105, 6626-6631, 2008. (link)