Chang-Hoon Choi, Ph.D.
Chang-Hoon Choi, Ph.D.
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Senior Scientist
Medical Imaging Physics
Institute of Neuroscience and Medicine - 4
Forschungszentrum Jülich, Jülich, Germany
Email: c.choi@fz-juelich.de
Websites: https://sites.google.com/view/mrichoi/home & https://sites.google.com/view/choiresearch/home
Fundamental and Advanced MRI M.Sc. Courses Coordinator and Senior Lecturer
Medical Engineering and Technomathematics
FH Aachen, Aachen University of Applied Sciences, Jülich, Germany
Courses: 2020/21WS, 2021SS, 2021/22WS, 2022SS, 2022/23WS, 2023SS, 2023/24WS, 2024SS, 2024/25, 2025SS, 2025/26WS
Email: choi@fh-aachen.de
Research interest [1]: MR-based Multi-modal system & technique design
Research interest [1]: MR-based Multi-modal system & technique design
IEEE RBME, Choi et al, 2024
IEEE TMI, Choi et al., 2022
EJNMMI Physics, Choi et al., 2020
IOP PMB, Choi et al., 2020
Grants
PI (Shah/Choi/Felder), Crossed J-pole antenna array for neuroscience and neuroradiology ultra-high field MRI, EFRE/JTF Programms NRW 2021-2027 (EFRE-20400006), 2024 - 2025.
PI (Choi), Mapping brain connectivity and plasticity using multimodal neuroimaging techniques with MR spectroscopy and focused ultrasound, DAAD, 2023 - 2025.
List of publications
Journal articles
M.-J. Chen, K.-H. Cho, …, C.-H. Choi, Technical development, integration and establishment of a hybrid preclinical simple MR-FUS system for simultaneous neuromodulation and imaging, IOP Phys. Med. Biol. (IF: 3.4), In submission.
C. Regio Brambilla, J. Hilgers, U. Khalid, N. Anasovi, T. Kikacheishvili, J. Mauler, C.-H. Choi, J. Scheins, N.J. Shah, C. Lerche, Innovations and Future Prospects for Image-derived Input Function in Molecular Imaging Quantification with 7T MR-BrainPET insert, Front. Neurosci. (IF:3.2), Minor revision.
J. Felder*, C.-H. Choi, S.-M. Hong, L. Tellmann, J. Scheins, C. Regio Brambilla, D. Niekämper, C.W. Lerche, I. Neuner, N.J. Shah, Design and implementation of a transceiver array for simultaneous PET/MRI/EEG at 7 tesla, Mag. Reson. Med. Q1 (IF: 3.0), Under review.
S. Krause*, A. Florea, C.-H. Choi et al., Autoradiography of intracerebral tumours in the chick embryo model: a feasibility study using different PET tracers, Mol. Imaging Biol. (IF: 3.0), DOI:10.1007/s11307-025-01983-9.
C.-H. Choi*, J. Felder, C. Lerche, N.J. Shah, 2024, MRI Coil Development Strategies for Hybrid MR-PET Systems: A Review, IEEE Reviews in Biomedical Engineering (IF: 17.6), 17: 342-350.
C.-H. Choi*, S.-M. Hong, J. Felder, L. Tellmann, J. Scheins, E. Rota Kops, C. Lerche, N.J. Shah, 2022, A novel J-shape antenna array for simultaneous MR-PET or MR-SPECT imaging, IEEE Trans. Med. Imaging (IF: 11.037), 41(5): 1104-1113.
A. Celik, C.-H. Choi*, L. Tellmann, C. Rick, N.J. Shah, J. Felder*, 2021, Design and construction of a PET compatible double-tuned, 1H/31P MR head coil, IEEE Trans. Med. Imaging (IF: 11.037), 40(8): 2015-2022.
C.-H. Choi, C. Stegmayr, A. Shymanskaya, W.A. Worthoff, N.A. da Silva, J. Felder, K-J. Langen, N.J. Shah*, 2020, An in vivo multimodal feasibility study in a rat brain tumour using flexible multinuclear MR and PET systems, EJNMMI Phys. (IF: 4.654), 7:50.
C. Stegmayr*, R. Surges, C.-H. Choi, N. Burda, G. Stoffels, C. Filß, A. Willuweit, B. Neumaier, A. Heinzel, N.J. Shah, F.M. Mottaghy, K-J. Langen, 2020, Investigation of cerebral O-(2-[18F]fluoroethyl)-L-tyrosine uptake in rat epilepsy models, Mol. Imaging Biol. (IF: 3.484), 22, 1255-1265.
C.-H. Choi*, T. Felder, J. Felder, L. Tellmann, S.-M. Hong, H.P. Wegner, N.J. Shah, K. Ziemons, 2020, Design, evaluation and comparison of endorectal coils for hybrid MR-PET imaging of the prostate, Phys. Med. Biol. (IF: 4.174), 65, 115005.
N.A. da Silva, P. Lohmann, J. Fairney, A.W. Magill, A. Oros-Peusquens, C.-H. Choi, R. Stirnberg, G. Stoffels, N. Galldiks, X. Golay, K-J. Langen, N.J. Shah*, 2018, Hybrid MR-PET of Brain Tumours using Amino Acid PET and Chemical Exchange Saturation Transfer MRI, Eur. J. Nucl. Med. Mol. Imaging, 45, pp.1031-1040.
A. Del Guerra*, … C.-H. Choi, et al., 2018, TRIMAGE: a dedicated trimodality (PET/MR/EEG) imaging tool for schizophrenia, Eur. Psychiatry, 50, pp. 7-20.
Patents
C.-H. Choi*(55%), S.-M. Hong (15%), J. Felder (15%), N.J. Shah (15%), Antenne, Antennenanordnung, Verfahren und Tomographiesystem (Filed in Apr 2025 - EP25171844.1).
C.-H. Choi*(40%), S.-M. Hong (20%), J. Felder (20%), N.J. Shah (20%), Antenne, Antennenanordnung, Verfahren und Tomographiesystem (Pending - DE102024201994A1).
N.J. Shah (45%), C.-H. Choi*(45%), J. Felder, Spulenanordnung für ein Tomographiesystem (Pending - DE102023201650A1; US2024288521A1).
C.-H. Choi*(40%), N.J. Shah (40%), et al., Spulenanordnung für ein Tomographiesystem (Pending - DE102023201651A1; US2024291156A1).
C.-H. Choi*(40%), et al., Dipolantennen-Array für hybride MR-PET und MR-SPECT Tomographen sowie dessen Verwendung und MR-PET oder MR-SPECT Tomograph mit einem Dipolantennen-Array (Granted - EP3980800B1; JP7550171B2; US12123931B2; ES2959829T3; HUE063779T2, Pending - DE102019003949A1; EP3980800A1; ES2959829T3; HUE063779T2; US2022236353A1; WO2020244689A1).
Book chapters
Hybrid MR-PET Imaging: Systems, Methods and Applications (Royal Society of Chemistry, Editor: Prof. N. Jon Shah) Chapter 18. Preclinical MR-PET hybrid scanner hardware (C.-H. Choi*, J. Felder, C. Lerche and N.J. Shah), 2019. https://doi.org/10.1039/9781788013062-00351.
Hybrid MR-PET Imaging: Systems, Methods and Applications (Royal Society of Chemistry, Editor: Prof. N. Jon Shah) Chapter 10. MR-PET hybrid system instrumentation (C. Lerche*, J. Felder, C.-H. Choi and N.J. Shah), 2019. https://doi.org/10.1039/9781788013062-00214.
Conference abstracts
M.J. Chen, K.-H. Cho, C.-C. Pan, E. Farrher, S.-M. Huang, P.-H. He, H.-H. Chiang, F. Küppers, N.J. Shah, H.-Y. Chang, G.-S. Chen, L.-W. Kuo, C.-H. Choi, Design, setup and establishment of a brain stimulation system and technique for hybrid 3 T MR-FUS in in vivo rats, Proc. ISMRM 2025 (Digital poster).
C. Lerche, D. Niekämper, J. Scheins, L. Tellmann, C.-H. Choi, et al., MR Compatibility Evaluation of a BrainPET Insert for UHF-MR Systems and Neuroscientific Applications, Proc. IEEE NSS MIC, 2024 (Poster presentation).
C. Lerche, D. Niekämper, J. Scheins, L. Tellmann, D. Ridder, Y. Kitten, P. Skudarnov, C.-H. Choi, et al., First Performance Results of a UHF-MRI Compatible BrainPET Insert for Neuroscience, Proc. IEEE NSS MIC, 2023 (Oral Presentation).
J. Wang, S. Krause, M. Schöneck, M. Cremer, T. Rüland, E. Farrher, C.-H. Choi, et al., Multi-modal evaluation of neuronal integrity in the visual pathway after retinal degeneration in RCS rats, Proc. DGBMT, 2023 (Oral presentation).
J. Wang, S. Krause, M. Schöneck, M. Cremer, T. Rüland, E. Farrher, C.-H. Choi, et al., Multi-modal evaluation of neuronal integrity in the visual pathway after retinal degeneration, Proc. ESMI, 2023 (Poster).
C. Balduin, M. Schöneck, C. Stegmayr, L. Liebenstund, J. Felder, W.A. Worthoff, C.-H. Choi, et al., A multimodal imaging approach for the detection of secondary neurodegeneration in a traumatic brain injury (TBI) model in rats using the PET tracer cis-4-[18F]-fluoro-D-proline (cis-F-D-proline) and new quantitative MR methods, Proc. ESMI, 2023 (Poster).
F. Mueller, D. Schug, B. Weissler, H. Radermacher, K. Krueger, L. Yin, V. Nadig, A. Mazur, A. Honne, J. Collienne, M. Lennartz, D. Grunwald, C.-H. Choi, J. Felder, J. Scheins, D. Niekaemper, C. Lerche, N.J. Shah, V. Schulz, Design of MRI-compatible PET module based on the Hyperion III platform for the BrainPET 7T project, Proc. IEEE NSS MIC, 2022 (Poster presentation).
F. Mueller, D. Schug, B. Weissler, H. Radermacher, K. Krueger, L. Yin, V. Nadig, A. Mazur, A. Honne, J. Collienne, C.-H. Choi, J. Felder, J. Scheins, C. Lerche, N.J. Shah, V. Schulz, Design of the BrainPET 7T project's UHF MRI-compatible PET module based on the Hyperion III platform, Proc. PSMR, 2022 (Poster).
C. Lerche, D. Niekämper, J. Scheins, M. Schöneck, W. Bi, D. Ridder, L. Tellmann, C.-H. Choi, et al., Development of an UHF-MRI compatible BrainPET insert for neuroscientific applications, Proc. Brain & BrainPET conference, 2022 (Poster presentation)
C.-H. Choi, S.-M. Hong, J. Felder, C. Lerche, N.J. Shah, Simulation of a shield effect on a J-pole antenna array for ultra-high field MR-PET, Proc. ISMRM, 2022 (Digital poster).
C.-H. Choi, S.-M. Hong, J. Felder, L. Tellmann, J. Scheins, E. Rota Kops, C. Lerche, N.J. Shah, Novel antenna array for ultra-high field MR-PET, Proc. ISMRM, 2021 (Digital poster).
F. Mueller, D. Schug, B. Weissler, H. Radermacher, K. Krueger, L. Yin, V. Nadig, A. Mazur, A. Honne, J. Collienne, C.-H. Choi, J. Felder, J. Scheins, C. Lerche, N.J. Shah, V. Schulz, Design of an UHF MRI-compatible PET module based on the Hyperion III platform, Proc. IEEE NSS MIC 2020, 1709 (Oral presentation).
C. Lerche, M. Lenz, W. Bi, D. Niekämper, J. Scheins, L. Tellmann, C.-H. Choi, et al., Design and Estimated Performance of a UHF-MRI Compatible BrainPET Insert for Neuroscience, Proc. IEEE NSS MIC 2020, 1133 (Digital poster).
C. Stegmayr, S. Bremen, C.-H. Choi, et al., In-vivo Tierversuchsersatzmodell zur präklinischen Tumordiagnostik: PET-MR im Hühnerembryo, Proc. Deutschen Gesellschaft für Nuklearmedizin, 2020;59(02):130 (E-poster)
C. Lerche, M. Lenz, W. Bi, J. Scheins, L. Tellmann, C.-H. Choi, et al., Design and Simulation of a high-resolution and high-sensitivity BrainPET insert for 7T MRI, Proc. Deutschen Gesellschaft für Nuklearmedizin, 2020;59(02):96 (E-poster).
C. Lerche, M. Lenz, W. Bi, J. Scheins, L. Tellmann, C.-H. Choi, et al., Design and construction of a high-resolution and high-sensitivity BrainPET insert for 7T MRI, PSMR, 2019 (Oral presentation).
C. Stegmayr, R. Surges, C.-H. Choi, A. Willuweit, P. Lohmann, B. Neumaier, N.J. Shah, K-J. Langen, Cerebral FET uptake owing to epilepsy appears to be a rare phenomenon, Proc. Deutschen Gesellschaft für Nuklearmedizin, 2019;58(02):162-163, DOI: 10.1055/s-0039-1683644 (Poster presentation).
C. Stegmayr, C.-H. Choi, A. Shymanskaya, W.A. Worthoff, N.A. da Silva, J. Felder, K-J. Langen, N.J. Shah, Feasibility study of a multinuclear MR-PET system in a rat brain tumour model, Proc. Deutschen Gesellschaft für Nuklearmedizin, 2018 (Oral presentation).
P. Lohmann, N.A. da Silva, J. Fairney, A.W. Magill, A. Oros-Peusquens, C.-H. Choi, R. Stirnberg, G. Stoffels, N. Galldiks, X. Golay, K-J. Langen, N.J. Shah, FET PET and chemical exchange saturation transfer MRI in brain tumours – a hybrid MR/PET study, Proc. Deutschen Gesellschaft für Nuklearmedizin, 2018.
C.-H. Choi, K. Ziemons, T. Felder, H.-P. Wegener, N.J. Shah, Design and evaluation of RF coils for hybrid MR-PET imaging of the prostate, Proc. ISMRM, 2018 (Traditional poster).
C.-H. Choi, C. Stegmayr, A. Shymanskaya, W.A. Worthoff, N.A. da Silva, J. Felder, K-J. Langen, N.J. Shah, Feasibility study of multinuclear MR at 9.4T and PET in a rat brain tumour model, Proc. ISMRM, 2018 (Traditional poster).
N.A. da Silva, P. Lohmann, J. Fairney, A.W. Magill, A. Oros-Peusquens, C.-H. Choi, R. Stirnberg, X. Golay, K-J. Lagen, N.J. Shah, Hybrid MR-PET of Brain Tumours with amino acid-PET and Amide Proton Transfer MRI, Proc., ISMRM, 2017 (Oral presentation).
C.-H. Choi, L. Tellmann, J. Felder, C. Lerche, N.J. Shah, An evaluation of RF coil materials for 1H/31P for use in a hybrid MR-PET scanner at 3T, Proc., ISMRM, 2017 (E-poster).
J. Cabello, S. Ahmad, M. Avram, J. Belcari, A. Berneking, L. Biagi, M.G. Bisogni, N. Camarlinghi, P. Cerello, C.-H. Choi, et al., TRIMAGE: A Simultaneous PET-MRI-EEG Brain Scanner Dedicated to Mental Disorders, Proc., ECCN, Rome, Italy, #P15, 2016.
Research interest [2]: tDCS-/FUS-MR (Neuromodulation)
Research interest [2]: tDCS-/FUS-MR (Neuromodulation)
Book chapter, Choi et al., 2025
Frontiers, Patel et al., 2024
Frontiers, Choi et al., 2024
HBM, Choi et al., 2021
Grants
PI (Choi/Shah), Mehrkanaliges hybrides transkranieller Gleichstromstimulation-Magnetresonanz-Radiofrequenz-Sensorarray/ Multi-tDCS-MR-RF-Sensorarray, EFRE/JTF Programms NRW 2021-2027 (Approved).
List of publications
Journal articles
C.-H. Choi*, N.J. Shah, F. Binkofski, Editorial: Exploration of the Human Brain using Magnetic Resonance Imaging and Spectroscopy with Transcranial Direct Current Stimulation, Frontiers in Neuroscience (IF: 3.2), DOI: 10.3389/fnins.2024.1538414.
H. Patel, L.-S. Stolberg, C.-H. Choi, M. Nitsche, N.J. Shah, F. Binkofski*, A Study of Long-Term GABA and High-Energy Phosphate Alterations in the Primary Motor Cortex Using Anodal tDCS and 1H/31P MR Spectroscopy, Frontiers in Neuroscience (IF: 3.2), DOI: 10.3389/fnhum.2024.1461417.
C.-H. Choi, E. Iordanishvili, N.J. Shah and F. Binkofski*, 2021, MR Spectroscopy with tDCS to explore the underlying biochemical and physiological mechanism of the human brain: A systematic review, Hum. Brain Mapp. (IF: 5.399), 42(8):2642-2671.
Patents
N.J. Shah* (55%), E. Farrher (15%), F. Küppers (15%), C.-H. Choi (15%), Verfahren und System zur Untersuchung eines Körpers mittels Magnetresonanztomographie, (Filed in May 2025 - EP25173908.2).
C.-H. Choi* (50%), N.J. Shah, Magnetresonanz – System mit transkranieller Gleichstromstimulation und Verfahren (Filed in Mar 2024 - DE102024201969A1).
Book chapters
Biokybernetika (De Gruyter Series in Mathematics and Life Sciences, Editor: Prof. Jochen Mau) An MR Spectroscopy Approach to Quantitatively Measure GABA and Phosphorus Level Changes in the Primary Motor Cortex Elicited by Transcranial Direct Current Stimulation (C.-H. Choi*, H. Patel, N.J. Shah and F. Binkofski), 2025. (Hardcover ISBN 978-3-11-134197-2, eBook: PDF ISBN 978-3-11-134199-6, ePUB ISBN 978-3-11-134204-7, https://doi.org/10.1515/9783111341996-023).
Exploration of the Human Brain using Magnetic Resonance Imaging and Spectroscopy with Transcranial Direct Current Stimulation (Frontiers, Editors: C.-H. Choi*, N.J. Shah, F. Binkofski), 2025. ISBN 978-2-8325-5860-7, https://doi.org/10.3389/978-2-8325-5860-7.
Conference abstracts
H. Patel, C.-H. Choi, N.J. Shah, F. Binkofski, A study of GABA and high energy phosphates change induced by anodal tDCS in the primary motor cortex of healthy subjects using 1H/31P MR spectroscopy, Proc. DGMP, 2022 (Poster presentation).
H.J. Patel, C.-H. Choi, L.-S. Stollberg, E. Iordanishvili, N.J. Shah, F. Binkofski, A 1H/31P MR spectroscopy study of GABA and high energy phosphates modulation induced by anodal tDCS in the primary motor cortex of healthy subjects, 65th DGKN, 2021 (Poster presentation).
H.J. Patel, C.-H. Choi, L.-S. Stollberg, E. Iordanishvili, E. Farrher, N.J. Shah, F. Binkofski, Proton magnetic resonance spectroscopy study of GABA neurotransmitter in motor cortex and basal ganglia of healthy subjects following anodal transcranial direct current stimulation, 14th German Neuroscience Society Conference, 2021 (Poster presentation).
C.-H. Choi, E. Iordanishvili, L.-S. Stollberg, H.J. Patel, N.J. Shah, F. Binkofski, Differential modulation of the cerebral energy consumption by two different transcranial direct current stimulation settings as measured by 31P MR spectroscopy, Proc. ISMRM, 2020 (Digital poster).
H.J. Patel, C.-H. Choi, N.J. Shah, F. Binkofski, A 1H/31P MRS study of ATP and GABA modulation induced by anodal transcranial direct current stimulation in primary motor cortex of healthy subjects, Proc. ISMRM, 2018 (Traditional poster).
Research interest [3]: Novel MR methodologies and applications
Research interest [3]: Novel MR methodologies and applications
IEEE Access, Choi et al., 2023
JMR, Choi et al., 2010
Grants
EU partner, A pilot study of ultra-high field magnetic resonance imaging technologies for brain neuroimaging and cardiovascular applications, MOST, 2019 - 2023.
PI (Choi), Exploring complex brain structures using MR Imaging, DAAD, 2017 - 2019.
PI (Choi), Decoding the human brain using 31P MR imaging and spectroscopy on ultra-high field clinical MRI scanners, FZJ international seed grant, 2018.
List of publications
Journal articles
E. Farrher*, K.-H. Cho*, C.-W. Chiang, M.-J. Chen, S.-M. Huang, L.-W. Kuo, C.-H. Choi, N.J. Shah, On the use of multi-echo NODDI MRI with released intrinsic diffusivity for the assessment of tissue diffusion and relaxation properties in experimental ischaemic stroke, NeuroImage (IF: 4.7), DOI:10.1016/j.neuroimage.2025.121390.
W.A. Worthoff, N.J. Shah, C.-H. Choi*, Editorial for "Sodium MRI of the lumbar intervertebral disks of the human spine: an ex vivo study", Journal of Magnetic Resonance Imaging (IF: 4.4), DOI:10.1002/jmri.29530.
C.-H. Choi*, E. Farrher, J. Felder, J. Wang, A. Willuweit, N.J. Shah, Project-oriented RF coil comparison and optimisation for preclinical, single-voxel MR spectroscopy at 9.4 T, IEEE Access (IF: 3.9), 11: 48601.
E. Farrher*, C.-W. Chiang, K.-H. Cho, F. Grinberg, R. Buschbeck, M.-J. Chen, K.-J. Wu, Y. Wang, S.-M. Huang, Z. Abbas, C.-H. Choi, N.J. Shah, L.-W. Kuo*, Spatiotemporal characterisation of ischaemic lesions in transient stroke animal models using diffusion free water elimination and mapping MRI with echo time dependence, NeuroImage (IF: 7.4), 244: 118605.
E. Farrher*, F. Grinberg, L.-W. Kuo*, K.-H. Cho, R. Buschbeck, H.-H. Chiang, M.-J. Chen, C.-H. Choi, N.J. Shah, 2020, Dedicated diffusion phantoms for the investigation of free water elimination and mapping: insights into the influence of T2 relaxation properties, NMR in Biomedicine (IF: 4.478), 33(4), e4210.
C.-H. Choi*, G.R. Davies and D.J. Lurie, 2010. Off-resonance Magnetisation Transfer Contrast MRI using Fast Field-Cycling, J. Magn. Reson., 204(1), pp. 145–149.
Book chapters
Quantitative MRI of the Brain: principles of physical measurement, 2nd Edition (Editors: Prof. M. Cercignani, Dr. N. Dowell, Prof. P. Tofts), Chapter 13: Multinuclear MR Imaging and Spectroscopy (Authors: W.A. Worthoff, A. Shymanskaya, C.-H. Choi, J. Felder, A. Oros-Peusquens, N.J. Shah), 2018. https://www.routledge.com/Quantitative-MRI-of-the-Brain-Principles-of-Physical-Measurement-Second/Cercignani-Dowell-Tofts/p/book/9781138032859.
Conference abstracts
E. Farrher, K.-H. Cho, R.P. Buschbeck, C.-W. Chiang, C.-H. Choi, M.-J. Chen, S.-M. Huang, L.-W. Kuo, N.J. Shah, Multi-echo NODDI with released intrinsic diffusivity in the healthy human brain tissue, Proc. ISMRM 2025 (Digital poster).
E. Farrher, C.-W. Chiang, K.-H. Cho, M.-J. Chen, S.-M. Huang, C.-H. Choi, L.-W. Kuo, N.J. Shah, Characterisation of compartmental diffusion and transverse relaxation properties of the rat ischemic tissue after MCAo, Proc. ISMRM 2025 (Digital poster).
S. Krause, A. Florea, C.-H. Choi, et al., Radiotracer evaluation in the chicken embryo tumour bearing brain: A feasibility study, Proc. EANM, 2024 (Poster).
E. Farrher, C.-W. Chiang, K.-H. Cho, C.-H. Choi, M.-J. Chen, S.-M. Huang, L.-W. Kuo, N.J. Shah, Multi-echo NODDI with released intrinsic diffusivity: initial insights for rat brain tissue, Proc. ISMRM, 2024 (Digital poster).
C.-W. Chiang, E. Farrher, K.-H. Cho, S.-M. Huang, N.J. Shah, C.-H. Choi, L.-W. Kuo, Quantitative evaluation of mannitol induced effects on ischemic rat brains using free water elimination and mapping with explicit T2 attenuation, Proc. ISMRM, 2023 (Oral presentation).
E. Farrher, C.-W. Chiang, C.-H. Choi, et al., Multi-echo NODDI for the study of tissue compartmentalisation in transient ischaemic stroke: initial insights, Proc. ISMRM, 2023 (Digital poster).
C.-W. Chiang, …, C.-H. Choi, L.-W. Kuo, Exploration of mannitol-treated dehydration in acute stroke using diffusion kurtosis imaging with free water elimination, Proc. ISMRM, 2020 (Digital poster).
E. Farrher, R.P. Buschbeck, K.-H. Cho, M.-J. Chen, S. Yun, A. Zaheer, C.-H. Choi, L.-W. Kuo, N.J. Shah, Rapid DTI-based free water elimination and mapping with explicit T2 modeling using a dual-echo Stejskal-Tanner EPI sequence, Proc. ISMRM, 2020 (Digital poster).
E. Farrher, …, C.-H. Choi, N.J. Shah, L.-W. Kuo, Spatiotemporal evolution of ischemic lesions in stroke animal models using free-water elimination and mapping with explicit T2 attenuation, Proc. ISMRM, 2020 (Digital poster).
K.-H. Cho, R. Buschbeck, S.-Y. Lin, E. Farrher, M.-J. Chen, C.-W. Chiang, N.J. Shah, C.-H. Choi, L.-W. Kuo, An in vivo investigation on quantitative metrics of diffusion kurtosis tensor: the effect of diffusion gradient parameters in the clinical setting, Proc. ISMRM, 2019 (Digital poster).
S.-M. Huang, K.-H. Cho, M.-J. Chen, H.-H. Chiang, C.-H. Choi, E. Farrher, R. Buschbeck, N.J. Shah, R. Garipov, C.-P. Chang, H. Chang, L.-W. Kuo, A 3T MRI platform for imaging rodent models by integrating the dedicated high-strength gradient coil on a whole-body magnet, Proc. ISMRM, 2019 (Digital poster).
R.P. Buschbeck, E. Farrher, K.-H. Cho, M.-J. Chen, S. Yun, C.-H. Choi, L.-W. Kuo, N.J. Shah, A Multi-Echo Stejskal-Tanner EPI Sequence for Rapid Measurements of T2 and Diffusion Tensor Correlations, Proc. ISMRM, 2019 (Digital poster).
C.-H. Choi, L. Volkovic, W. Clarke, A.I. Schmid, N.J. Shah, C.T. Rodgers, NOE enhancement for 31P-MRS of skeletal and cardiac muscle at 7T, Proc. ISMRM, 2019 (Digital poster).
A. Shymanskaya, W.A. Worthoff, C.-H. Choi, J. Felder, N.J. Shah, Application of strongly modulated pulses in triple quantum filtering for in vivo animal sodium MRI, Proc., ISMRM X-nuclei workshop, 2018 (Traditional poster).
H.-H. Chiang, K.-H. Cho, E. Farrher, J. Lindemeyer, R. Buschbeck, F. Grinberg, N.J. Shah, C.-H. Choi, L.-W. Kuo, Design of multi-purpose and 3D-printed fibre phantoms for investigating complex tissue microstructures, Proc. ISMRM, 2018 (E-poster).
E. Farrher, R. Buschbeck, C.-H. Choi, L.-W. Kuo, S. Yun, F. Grinberg, N.J. Shah, In vivo DTI-based free-water elimination with T2-weighting, Proc., ISMRM, 2018 (Traditional poster).
E. Farrher, K.-H. Cho, R. Buschbeck, M.-J. Chen, H.-H. Chiang, F. Grinberg, N.J. Shah, C.-H. Choi, L.-W. Kuo, DTI-based free-water elimination with T2-weighting using dedicated anisotropic diffusion fibre phantoms, Proc., ISMRM, 2018 (Traditional poster).
E. Farrher, K.-H. Cho, R. Buschbeck, M.-J. Chen, H.-H. Chiang, F. Grinberg, N.J. Shah, C.-H. Choi, L.-W. Kuo, Investigating complex structural characteristics using diffusion MRI on multi-sectional anisotropic fibre phantoms, Proc., ESMRMB, 2017 (E-poster with lightening talk).
P. Veeraiah, C.-H. Choi, M. Schöneck, A. Willuweit, J. Felder, K. Ziemons, N.J. Shah, In vivo multinuclear 1H, 17O, 23Na MRI and 31P MRS of healthy rat brain at 9.4T, Proc., ESMRMB, 2017 (E-poster with lightening talk).
A. Shymanskaya, W.A. Worthoff, C.-H. Choi, J. Felder, N.J. Shah, Triple quantum filtering in in vivo animal sodium MRI using strongly modulated pulses, Proc., ESMRMB, 2017 (Oral presentation).
C.-H. Choi, Y. Ha, P. Chervakov, N.J. Shah, A study of NOE enhancement in 31P MR spectroscopy with respect to 1H coil size in a double-tuned coil at 3T, Proc., ESMRMB, 2017 (E-poster with lightening talk).
A. Shymanskaya, W.A. Worthoff, C.-H. Choi, N.J. Shah, Enhanced Simultaneous Multiple Quantum Filtered Sodium Magnetic Resonance Imaging, Proc., ESMRMB, 2016 (Oral presentation).
D.J. Lurie, L. Broche, C.-H. Choi, et al. NMR relaxometry and MRI using Fast field-cycling, Proc., AMPERE NMR School, Poznan, Poland, 2012.
D.J. Lurie, L. Broche, C.-H. Choi, et al. Field-Cycling MRI – techniques and applications, Proc., AMPERE NMR School, Zakopane, Poland, 2011.
D.J. Lurie, L. Broche, C.-H. Choi, et al. Fast Field-Cycling MRI, Proc., 7th Conference on Field Cycling NMR Relaxometry, Torino, Italy, #O19, 2011.
C.-H. Choi, D.J. Lurie. Magnetic field-dependent magnetisation transfer contrast MRI using fast field-cycling, Proc., ISMRM, 2011 (E-poster).
D.J. Lurie, L. Broche, C.-H. Choi, et al. Field-Cycling magnetic resonance imaging, Proc., AMPERE NMR School, Wierzba, Poland, 2011.
D.J. Lurie, L. Broche, C.-H. Choi, et al. Polarisation manipulation in MRI by magnetic field-cycling and DNP, Proc., 10th ICMRM, West Yellowstone, USA, 2009.
C.-H. Choi, G.R. Davies, D.J. Lurie. The use of Fast Field-Cycling technique with Magnetisation Transfer Contrast MRI, Proc., 6th Conference on Field Cycling NMR Relaxometry, Torino, Italy, #P11, 2009 (Traditional Poster).
D.J. Lurie, L. Broche, C.-H. Choi, et al. Fast Field-Cycling MRI, Proc., 6th Conference on Field Cycling NMR Relaxometry, Torino, Italy, #O10, 2009.
C.-H. Choi, G.R. Davies, D.J. Lurie. Off-resonance Magnetisation Transfer Contrast MRI using Fast Field-Cycling technique, Proc., ISMRM, 2009 (Traditional poster and Educational travel award).
D.J. Lurie, C.-H. Choi, G.R. Davies, et al. Fast Field-Cycling Magnetic Resonance Imaging, Proc., 4th Meeting of the Saudi Physical Society, Riyadh, Saudi Arabia, 2008.
D.J. Lurie, C.-H. Choi, G.R. Davies, et al. Principles and Applications of Magnetic Field Cycling in MRI, Proc., 20th International Conference of the Society for Medical Innovation and Technology, Austria, 2008.
C.-H. Choi, D.J. Lurie. Implementation of Magnetisation Transfer Contrast MRI at low field, Proc., AMPERE NMR School, Wierzba, Poland, #52, 2008 (Traditional Poster).
Research interest [4]: Novel MR hardware and systems development
Research interest [4]: Novel MR hardware and systems development
IEEE RBME, Choi et al., 2024
MRI, Choi et al., 2020
JMR, Choi et al., 2017
JMR, Choi et al., 2016
List of publications
Journal articles
M.-J. Chen, K.-H Cho, H.-H. Chiang, C.-H. Choi, et al., Development, integration and performance evaluation of a high-strength gradient system on an in-house dedicated 3 T whole body MRI scanner, Phys. Med. Biol. (IF: 3.3), In submission.
C.-T. Chen, K.-H. Cho, M.-J. Chen, P.-H. He, H.-H. Chiang, E. Farrher, N.J. Shah, C.-P. Lin*, L.-W. Kuo*, C.-H. Choi, Design and evaluation of a multi-purpose RF coil for adaptively improving regional MR image quality in the mouse brain, Med. Phys. (IF: 3.2), R3.
S.-H. Hong*, C.-H. Choi, J. Felder, N.J. Shah, Technical note: novel 1H/19F double-tuned coil using a circularly polarised butterfly coil, Med. Phys. (IF: 3.2), DOI: 10.1002/mp.17890.
C.-H. Choi*, S.-M. Hong, J. Felder, M. Bruch, W.A. Worthoff, S. Krause, N.J. Shah, Design, construction, and use of a tapered-spiral, quadrature 1H/23Na double-tuned coil for in ovo MRI at 7 T, Med. Phys. (IF: 3.2), DOI: 10.1002/mp.17448.
C.-H. Choi*, M. Bruch, S.-M. Hong, S. Krause, C. Stegmayr, S. Schwan, W.A. Worthoff, J. Felder, N.J. Shah, A modified quadrature birdcage coil incorporated with a curved feature for in ovo MRI, IEEE Open Journal of Engineering in Medicine and Biology (IF: 5.8), 5:534-541.
C.-H. Choi, A. Webb, S. Orzada, M. Kelenjeridze, N.J. Shah, J. Felder*, A review of parallel transmit arrays for ultra-high field MR imaging, IEEE Reviews in Biomedical Engineering (IF: 17.6), 17: 351-368.
S.-M. Hong*, C.-H. Choi, N.J. Shah, J. Felder, A novel circularly polarised butterfly RF coil concept for MRI, IEEE Access (IF: 3.9), 12: 2567-2572.
S.-M. Hong*, C.-H. Choi, N.J. Shah, J. Felder, Design of a folded, double-tuned loop coil for 1H/X-nuclei MRI applications, IEEE Trans. Med. Imaging (IF: 11.037), 42(5): 1424-1430.
C.-H. Choi*, S.-M. Hong, N.J. Shah, J. Felder, Design and comparison of different types of dual-frequency matching networks used in double-tuned coils for multinuclear magnetic resonance imaging and spectroscopy, IEEE Access (IF: 3.9), 10: 123899-123904.
J. Felder*, C.-H. Choi, Y. Ko, N.J. Shah, 2020, Optimization of high-channel count, switch matrices for multinuclear, high-field MRI, PLoS ONE (IF: 3.752),15(8):e0237494.
C.-H. Choi*, S. Hong, J. Felder and N.J. Shah, 2020, The state-of-the-art and emerging design approaches of double-tuned RF coils for X-nuclei, brain MR imaging and spectroscopy: A review, Magn. Reson. Imaging (IF: 3.13), 72, 103-116.
K.-H. Cho, S.-M. Huang, C.-H. Choi, M.-J. Chen, H.-H. Chiang, R. Buschbeck, E. Farrher, N.J. Shah, R. Garipov, C.-P. Chang, H. Chang, L.-W. Kuo*, 2019, Development, integration and use of an ultra-high-strength gradient system on a clinical 3 T magnet for small animal MRI, PLoS ONE 14(6), e0217916.
S.-M. Hong*, C.-H. Choi, N.J. Shah, J. Felder, 2019, Design of a double-resonant helmet coil for 1H/31P at 3T MRI, Phys. Med. Biol., 64, pp. 035003.
Y.-K. Ko, S. Yun, S.-M. Hong, Y. Ha, C.-H. Choi, N.J. Shah, J. Felder*, 2018, MR-compatible, 3.8 inch dual organic light-emitting diode (OLED) in-bore display for functional MRI, PLoS ONE, 13(10): e0205325.
Y.-K. Ko, C.-H. Choi, N.J. Shah, J. Felder*, 2018, Signal Loss Compensation of RF Crossbar Switch Matrix System in Ultra-High Field MRI, IEEE Trans. Biomed. Circuits and Systems, 12, pp. 1458-1466.
S.-M. Hong*, C.-H. Choi, A.W. Magill, N.J. Shah, J. Felder, 2018, Design of a quadrature 1H/31P coil using bent dipole antenna and 4-channel loop at 3T MRI, IEEE Trans. Med. Imaging (IF: 11.037), 37, pp. 2613-2618.
Y. Ha1, C.-H. Choi1,*, N.J. Shah, 2018, Development and implementation of a PIN-diode controlled, quadrature-enhanced, double-tuned RF coil for sodium MRI, IEEE Trans. Med. Imaging (IF: 11.037), 37, pp. 1626-1631 (The first authorship is shared between Choi and Ha).
Y. Ha1, C.-H. Choi1,*, W.A. Worthoff, A. Shymanskaya, M. Schöneck, A. Willuweit, J. Felder and N.J. Shah, 2018, Design and in vivo use of a folded four-ring double-resonant quadrature birdcage coil for rat brain sodium imaging at 9.4T, J. Magn. Reson., 286, pp. 110-114 (The first authorship is shared between Choi and Ha).
J. Felder*, A. Celik, C.-H. Choi, S. Schwan and N.J. Shah, 2017, 9.4T Small Animal MRI Using Clinical Components for Direct Translational Studies, J. Transl. Med., 15, pp. 264.
C.-H. Choi*, S. Hong, Y. Ha and N.J. Shah, 2017, Design and construction of a novel 1H/19F double-tuned coil system using PIN-diode switches at 9.4T, J. Magn. Reson., 279, pp.11-15.
C.-H. Choi*, Y. Ha, P. Veeraiah, J. Felder, K. Moellenhoff and N.J. Shah, 2016, Design and implementation of a simple multinuclear MRI system for ultra high-field imaging of animals, J. Magn. Reson., 273, pp. 28-32.
C.-H. Choi, J.M.S. Hutchison and D.J. Lurie*, 2010, Design and construction of an actively frequency-switchable RF coil for fast field-cycling magnetisation transfer contrast MRI, J. Magn. Reson., 207(1), pp. 134-139.
D.J. Lurie*, S. Aime, S. Baroni, N.A. Booth, L. Broche, C.-H. Choi, et al., 2010. Fast Field-Cycling MRI, C. R. Physique, 11(2), pp. 136-148.
Patents
S.-M. Hong* (25%), C.-H. Choi (25%), J. Felder (25%), N.J. Shah (25%), Dipol-Empfangsantenne, Herstellungs verfahren und Empfangsantennen-Anordnung, (Filed in Sep 2025 - EP25200067.4).
C.-H. Choi*(40%), et al., Antenne, System und Antennenanordnung sowie zugehöriges Verfahren (Filed in May 2024 - DE102024112391A1).
S.-M. Hong*, N.J. Shah, C.-H. Choi (25%), J. Felder, Spule, Spulenanordnung und Verfahren, (Filed in April 2023).
C.-H. Choi*(30%), et al., Spulenarray und dessen Verwendung (Pending - DE102020005044A1; EP4200626A1; WO2022037737A1).
S.-M. Hong* (25%), J. Felder (25%), N.J. Shah (25%), C.-H. Choi (25%), Doppeltresonante Spule sowie Array von doppeltresonanten Spulen und deren Verwendung (Granted - EP4118444B1, Pending - DE102021000282A1; EP4118444A1; US2023078150A1; WO2021180259A1).
C.-H. Choi*(30%), et al., Doppelt abgestimmte Empfangsspule für ein Magnetresonanztomographie-System (Pending - DE102020205632A1; EP4147064A1; WO2021223977A1).
C.-H. Choi*(30%), et al., Modular anpassbare Spule und Spulenanordnung für ein Magnetresonanztomographiesystem (Pending - DE102020205363A1).
S.-M. Hong* (25%), N.J. Shah (25%), C.-H. Choi (25%), J. Felder (25%), Spulenanordnung, MR-System, insbesonndere MRT – und/oder MRS-System, mit einer solchen Spulenanordnung sowie Verwendung einer solchen Spulenanordnung (Granted - US12181545B2, DE102019105021B3, Pending - EP3931585A1; JP2022521611A; US2022137165A1; WO2020173590A1).
Book chapters
Hybrid MR-PET Imaging: Systems, Methods and Applications (Royal Society of Chemistry, Editor: Prof. N. Jon Shah) Chapter 2. MRI instrumentation (J. Felder*, C.-H. Choi and N.J. Shah), 2019. https://doi.org/10.1039/9781788013062-00045.
Conference abstracts
C.-H. Choi, N.J. Shah, The use of simple, wireless Lenz lens for ultra-high field preclinical MRI at 9.4 T: a preliminary result, Proc. ISMRM 2025 (Digital poster).
S.-M. Hong, C.-H. Choi, J. Felder, H.J. Lee, C.-S. Kim, M-K. Woo, N.J. Shah, Numerical evaluations of bent dipole antenna for prostate imaging at 3T MRI, Proc. ESMRMB, 2024 (Poster).
C.-H. Choi, S.-M. Hong, J. Felder, N.J. Shah, A comparison of double-matching networks in a double-tuned coil for multinuclear MRI, Proc. ISMRM, 2022 (Digital poster).
K.-H. Cho, P.-H. He, H.-H. Chiang, M.-J. Chen, E. Farrher, N.J. Shah, C.-H. Choi, L.-W. Kuo, A simple, multi-purpose coil for Improved Mouse Brain image quality and coverage at 3-T MRI, Proc. ISMRM, 2021 (Digital poster).
C.-H. Choi, ... N.J. Shah, A novel interchangeable, double-tuned, twin head coil array design for 1H/23Na MR imaging and 1H/31P MR spectroscopy at 7T, Proc. ISMRM, 2020 (Oral presentation).
S.-M. Hong, C.-H. Choi, J. Felder, N.J. Shah, Numerical evaluation of a domed and folded-ring, double-tuned birdcage coil for 1H/31P at 3T MRI, Proc. ISMRM, 2020 (Digital poster).
S.-M. Hong, C.-H. Choi, J. Felder, N.J. Shah, Design and evaluation of dual-tuned circular dipole antenna up to 14T MRI, Proc. ISMRM, 2020 (Digital poster).
Y.-K. Ko, C.-H. Choi, N.J. Shah, J. Felder, The miniaturisation and simplification of a crossbar switch matrix system using stacked switch blocks, Proc. ISMRM, 2019 (Digital poster).
Y.-K. Ko, S. Yun, J. Felder, C.-H. Choi, N.J. Shah, MR-Compatible, Organic Light-Emitting Diode (OLED) display for functional MRI, Proc. ISMRM, 2018 (Traditional poster).
Y. Ha, C.-H. Choi, J. Felder, N.J. Shah, A receive-only, double-tune coil using preamplifier decoupling, Proc., ISMRM, 2018 (E-poster).
S.-M. Hong, C.-H. Choi, J. Felder, N.J. Shah, Design and simulation of dual-band dipole antenna for 1H/31P at 9.4T MRI, Proc. ISMRM, 2018 (E-poster).
D. Koh, J. Felder, C.-H. Choi, N.J. Shah, Wavelength independent λ/40 Composite Right/Left-Handed Transmission Line Coil, Proc. ISMRM, 2018 (E-poster).
S.-M. Hong, C.-H. Choi, J. Felder, N.J. Shah, Dual-resonant helmet coil for 1H/31P at 3T MRI, Proc. ISMRM, 2018 (Traditional poster).
M.-J. Chen, K.-H. Cho, C.-H. Choi, E. Farrher, R. Buschbeck, H.-H. Chiang, N.J. Shah, H. Chang, L.-W. Kuo, A feasibility study of ultra-high-strength gradient system on 3T: demonstration using DTI on anisotropic diffusion fibre phantoms, Proc. ISMRM, 2018 (Traditional poster).
Y.-K. Ko, C.-H. Choi, N.J. Shah, A Signal Loss Compensation Method in an RF switch matrix system in Ultra High Field MRI, Proc. ISMRM, 2018 (Traditional poster).
M.-J. Chen, K.-H. Cho, C.-H. Choi, E. Farrher, R. Buschbeck, H.-H. Chiang, N.J. Shah, H. Chang, L.-W. Kuo, Integration of ultra-high-strength, multi-scale and switchable gradient systems on a whole-body 3T magnet: diffusion MRI feasibility demonstration, Proc. ESMRMB, 2017 (E-poster with lightening talk).
Y. Ha, C.-H. Choi, N.J. Shah, Implementation of a quadrature-compensated, double-tuned coil at 9.4T, Proc., ESMRMB, 2017 (E-poster with lightening talk).
Y. Ha, C.-H. Choi, N.J. Shah, An actively decoupled, double-tuned, receive only RF coil design, Proc., ESMRMB, 2017 (E-poster).
C.-H. Choi, Y. Ha, W. Worthoff, A. Shymanskaya, M. Schöneck, A. Willuweit, J. Felder, N.J. Shah, In vivo rat sodium imaging at 9.4T using a folded four-ring double-resonant quadrature birdcage coil, Proc., ESMRMB, 2017 (E-poster with lightening talk).
Y. Ko, H.L. Lee, C.-H. Choi, N.J. Shah, A technique to compensate signal loss in an RF switch matrix system in MRI, Proc., ISMRM, 2017 (Traditional poster).
S. Hong, C.-H. Choi, J. Felder, A.W. Magill, N.J. Shah, A bent dipole antenna and 4-channel loop array for 1H/31P brain application at 3T MRI, Proc., ISMRM, 2017 (E-poster).
Y. Ha, C.-H. Choi, N.J. Shah, Folded four-ring double-tuned birdcage coil design, Proc., ISMRM, 2017 (E-poster).
Y. Ha, A.W. Magill, C.-H. Choi, N.J. Shah, PIN-diode switched dual-tuned RF coils, Proc., ISMRM, 2017 (E-poster).
J. Felder, C.-H. Choi, N.J. Shah, Loopoles vs. conventional MR loops under safety considerations, Proc., ISMRM, 2017 (E-poster).
C.-H. Choi, S. Hong, Y. Ha, N.J. Shah, Design and construction of a novel double-tuned 1H/19F coil using PIN-diode switches at 9.4T, Proc., ISMRM, 2017 (E-poster).
Y. Ha, A.W. Magill, C.-H. Choi, N.J. Shah, PIN-diode switched dual-tuned RF coils, Proc., ESMRMB, 2016 (E-poster).
C.-H. Choi, Y. Ha, A.W. Magill, N.J. Shah, Design of quadrature-compensated double-tuned RF surface coil using trap circuits, Proc., ISMRM, 2016 (Traditional poster).
C.-H. Choi, Y. Ha, P. Veeraiah, J. Felder, K. Moellenhoff, N.J. Shah, Development of translational simple multinuclear MRI system for ultra high-field, Proc., ISMRM, 2016 (E-poster).
A.W. Magill, C.-H. Choi, Y. Ha, N.J. Shah, Design and construction of a triple-tuned RF probe for 23Na/31P/1H using traps, Proc., ISMRM, 2016 (Traditional poster).
J. Felder, C.-H. Choi, et al., 9.4 T Preclinical MRI Scanner for translation research with binary compatibility to human scanner and clinical UI, Proc., ISMRM, 2016 (E-poster).
C.-H. Choi, Y. Ha, P. Veeraiah, K. Moellenhoff, N.J. Shah, Design and implementation of simple multinuclear preclinical MRI system at ultra high-field, Proc., ESMRMB, 2015 (E-poster with lightening talk).
C.-H. Choi, I. Lavdas, J.M.S. Hutchison, D.J. Lurie. Design and construction of an actively frequency-switchable RF coil for fast field-cycling magnetisation transfer contrast MRI, Proc., ISMRM, 2010 (E-poster and Educational travel award).
D.J. Lurie, L. Broche, C.-H. Choi, et al. 1000 Field Strengths in One Scanner - Fast Field-Cycling MRI, Proc., AMPERE NMR School, Zakopane, Poland, 2009.
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