About

The Choi Lab aims to uncover the molecular rationale underlying therapeutic refractoriness in brain tumors, particularly gliomas. Despite remarkable advances in cancer research, gliomas remain among the most aggressive and treatment-resistant malignancies. Our mission is to bridge molecular understanding with clinical relevance—integrating multi-omics data, phenotypic observations, and clinical insights to reveal the biological principles that govern tumor behavior and therapy response.

In the long term, our goal is to translate these discoveries into actionable precision medicine strategies that not only improve the outcomes of patients with malignant brain tumors but also inform broader approaches to therapy resistance in other refractory cancers. Through data-driven discovery and interdisciplinary collaboration, we seek to transform the way we understand, predict, and ultimately overcome treatment failure in neuro-oncology and beyond.