Publication
Establish G protein-deficient vesicular stomatitis virus (VSV) pseudovirus expressing SARS-CoV-2 spike protein system for antibody neutralization and drug screening
TLR9 and STING agonists cooperatively boost the immune response to SARS-CoV-2 RBD vaccine through an increased germinal center B cell response and reshaped T helper responses. Jing-Xing Yang, Jen-Chih Tseng, Chih-Feng Tien, Chia-Yin Lee, Yi-Ling Liu, Jhe-Jhih Lin, Pei-Ju Tsai, Hung-Chun Liao, Shih-Jen Liu, Yu-Wen Su, Li-Chung Hsu, Jen-Kun Chen, Ming-Hsi Huang, Guann-Yi Yu, Tsung-Hsien Chuang. Int J Biol Sci 19(9):2897-2913 (2023).
Glycosylation and S-palmitoylation regulate SARS-CoV-2 spike protein intracellular trafficking. Chih-Feng Tien, Wan-Ting Tsai, Chun Hwa Chen, Hui-Ju Chou, Mingzi M Zhang, Jhe-Jhih Lin, En-Ju Lin, Shih-Syong Dai, Yueh-Hsin Ping, Chia-Yi Yu, Yi-Ping Kuo, Wei-Hsiang Tsai, Hsin-Wei Chen, Guann-Yi Yu. iScience 19;25(8):104709 (2022). [IF=5.8]
Furin and TMPRSS2 Resistant Spike Induces Robust Humoral and Cellular Immunity Against SARS-CoV-2 Lethal Infection. Jhe-Jhih Lin, Chih-Feng Tien, Yi-Ping Kuo, En-Ju Lin, Wei-Hsiang Tsai, Ming-Yu Chen, Pei-Ju Tsai, Yu-Wen Su, Nikhil Pathak, Jinn-Moon Yang, Chia-Yi Yu, Zih-Shiuan Chuang, Han-Chieh Wu, Wan-Ting Tsai, Shih-Syong Dai, Hung-Chun Liao, Kit Man Chai, Yu-Siang Su, Tsung-Hsien Chuang, Shih-Jen Liu, Hsin-Wei Chen, Horng-Yunn Dou, Feng-Jui Chen, Chiung-Tong Chen, Chin-Len Liao and Guann-Yi Yu. Frontiers in immunology 13, 872047 (2022). [IF=7.3]
The effects of Aβ1-42 binding to the SARS-CoV-2 spike protein S1 subunit and angiotensin-converting enzyme 2. John Tsu-An Hsu, Chih-Feng Tien, Guann-Yi Yu, Santai Shen, Yi-Hsuan Lee, Pei-Chien Hsu, Yun Wang, Po-Kuan Chao, Huey-Jen Tsay, Feng-Shiun Shie. Int. J. Mol. Sci. 22(15), 8226 (2021). [IF=6.208]
新冠肺炎COVID-19藥物發展。田至峰，蔡宛庭，蔡瑋祥，余冠儀。感控雜誌202302_33(1):51-55 (2023)
對抗新型冠狀病毒之疫苗與藥物發展趨勢。林哲志, 田至峰, 余冠儀。感控雜誌202006_30(3):196-200 (2020)
Human immunodeficiency virus type 1 (HIV-1) -the mechanism of precursor autoprocessing
Decoupling of HIV-1 Protease Precursor Trans Proteolytic Activity from Its Dimerization Propensity. Chih-Feng Tien, Liangqun Huang, Molly R Kulikauskas, Satoshi Machihara, Carol Carter, Chaoping Chen. (2023-2024) (Manuscript in preparation)
Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery against HIV Infection and Drug Resistance Assessment. Liangqun Huang, Linfeng Li, ChihFeng Tien, Daniel V. LaBabera, Chaoping Chen. Scientific Reports 9(1),301 (2019) [IF=3.998]
Context-dependent autoprocessing of human immunodeficiency virus type 1 protease precursors. ChihFeng Tien*, Liangqun Huang*, Susan M Watanabe, Jordan T Speidel, Carol A Carter, Chaoping Chen. PLoS ONE 13(1): e0191372 (2018) [IF=2.776]*contributed equally
Japanese encephalitis virus (JEV) - RNA-protein interaction in viral replication
The conserved stem-loop II structure at the 3' untranslated region of Japanese encephalitis virus genome is required for the formation of subgenomic flaviviral RNA. Yi-Shiuan Chen, Yi-Hsin Fan, Chih-Feng Tien, Andrew Yueh, and Ruey-Yi Chang. PLoS ONE 13(7): e0201250 (2018) [IF=2.776]
Inhibition of aldolase A blocks biogenesis of ATP and attenuates Japanese encephalitis virus production. Chih-Feng Tien*, Shih-Ching Cheng*, Yen-Peng Ho, Yi-Shiuan Chen, Jung-Hsin Hsu, and Ruey-Yi Chang. Biochemical and Biophysical Research Communications 443: 464-469. (2014) [IF=2.297] *contributed equally
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3’ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 protein. Shang-Hua Yang, Mei-Lan Liu, Chih-Feng Tien, Shih-Jie Chou, and Ruey-Yi Chang. Journal of Biomedical Science 16:40. (2009) [IF=2.736]. Highly accessed.
Citation : https://scholar.google.com/citations?hl=en&user=RIm5NL4AAAAJ