The synthesis of drug molecules for treating life-threatening diseases is a promising field for both Academics and Industries. To achieve that, it is essential to develop novel, greener methods that can be widely applied to access biologically active diverse molecular structures with structural complexicity. In this context, various methods such as domino reactions, multicomponent reactions, transition metal-catalyzed reactions, organocatalysis, and catalysis using efficient materials have been extensively explored. One recent topic of interest in homogeneous catalysis is the specific transformation of C-H bonds into C-C, C-O, C-N and C-X bonds. This is important in modern synthesis, as it allows the production of target compounds that would otherwise require lengthy multi-step synthesis strategies. Catalytic C-H functionalization is a particularly appealing approach for this purpose because it does not require stoichiometric amounts of activating reagents and produces less waste as byproducts. 

Based on that, our research is mainly focused on the followings: 

• Development of novel methodology reactions under mild conditions that can be applied for the total synthesis of some bioactive natural products. 

• Transition-metal-catalyzed directing group assisted ortho-C-H bond activation of arenes for functionalizations. 

• Unreactive C(sp3)-H bond activation reactions using transition metal catalysts.