Hypophosphatasia (h-p-fs-f-t-zh(-)) or HPP is an inherited (genetic) metabolic disorder. People with this condition have low levels of the enzyme alkaline phosphatase (ALP), which often affects the development of bones and teeth.
Why does bone health matter? How can you improve bone health and prevent osteoporosis? You can start by reading about the important role of bones in your body. Learn more below about what you can do to keep your bones strong and healthy, what the risk factors are for osteoporosis, and how to live well if you have osteoporosis:
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Subchondral tissue. This is the smooth tissue at the ends of bones, which is covered with another type of tissue called cartilage. Cartilage is a specialized, rubbery connective tissue.
The tough, thin outer membrane covering the bones is called the periosteum. Under the hard outer shell of the periosteum are tunnels and canals. Through these, blood and lymphatic vessels carry nourishment for the bone. Muscles, ligaments, and tendons may attach to the periosteum.
Bones give shape and support for the body. They give protection to some organs. Bone also serves as a storage site for minerals. And soft bone marrow in the center of certain bones is where blood cells are formed and stored.
The bones of the body come in a variety of sizes and shapes. The four principal types of bones are long, short, flat and irregular. Bones that are longer than they are wide are called long bones. They consist of a long shaft with two bulky ends or extremities. They are primarily compact bone but may have a large amount of spongy bone at the ends or extremities. Long bones include bones of the thigh, leg, arm, and forearm.
Short bones are roughly cube shaped with vertical and horizontal dimensions approximately equal. They consist primarily of spongy bone, which is covered by a thin layer of compact bone. Short bones include the bones of the wrist and ankle.
Bones that are not in any of the above three categories are classified as irregular bones. They are primarily spongy bone that is covered with a thin layer of compact bone. The vertebrae and some of the bones in the skull are irregular bones.
All bones have surface markings and characteristics that make a specific bone unique. There are holes, depressions, smooth facets, lines, projections and other markings. These usually represent passageways for vessels and nerves, points of articulation with other bones or points of attachment for tendons and ligaments. 589ccfa754
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