Dr. R. Karthik Raja
Associate Professor, HoD
Center for Applied Research,
Saveetha School of Engineering,
SIMATS Deemed University,
Chennai, Tamil Nadu, India.
Email: karthickraja.sse@saveetha.com
Phone: 9944709893
Embedded Files
Publications: Scopus- 40, SCI - 30, WOS - 30
H Index: 17, Citation: 453, i10 Index: 21
Thomson Reuters Impact Factor: 96.96
Research Interest
· Pest control using nano-formulations
· Isolation and Identification of Entomopathogenic Nematodes & its Symbiotic Bacteria
· Ecological Characterization of Entomopathogenic Nematodes
· Mass Production of Entomopathogenic Nematodes
Awards and Honors
Awards and Honors
Awarded “Young Scientist Award” from Department of Science and Technology (DST), Government of India, New Delhi, India
Awarded “Travel Grant” from Department of Biotechnology (DBT), Govt. of India, New Delhi to attend an International conference in Canada.
Awarded “Travel Grant” from CICS, Govt. of India, Chennai to attend an International conference in Canada.
Awarded “Research Fellowship for Foreign Citizens” for a period of one year (2012-2013) funded by Scientific and Technological Research Council of Turkey (TUBITAK), Government of Turkey.
Awarded “Turkish Government Scholarships 08-09” for doing research from February – December 2009 with Dr. Selcuk HAZIR, Adnan Menderes University, Turkey by Govt. of India and Govt. of Turkey Student exchange program.
Worked as a “Project Fellow” from June, 2007- January, 2009 in the project entitled Exploitation of Novel Fungal and Entomophagous Nematode for the Control of Soil Invading Insect Pests and Subterranean Termites sponsored by University Grants Commission, Govt. of India
Books and Book Chapters:
Books and Book Chapters:
Book:
Karthik Raja. R., Padmanaban. K and Sivaramakrishnan. S. (2011). Entomopathogenic Nematodes: A Best Bio-control Agent for Insect Pest. Lambert Academic Publishing, ISBN: 978-3-8454-2084-4
Sivaramakrishnan. S., Chitra. S and Karthik Raja. R. (2013). Entomophogenic Fungi for vector control. Lambert Academic Publishing, ISBN:978-3-659-34000-0.
Book Chapters indexed in Scopus (5)
Book Chapters indexed in Scopus (5)
R. Karthik Raja, Selcuk Hazir, Govindan Balasubramani, G Sivaprakash, Ebenezer Samuel James Obeth, Thulasinathan Boobalan, Arivalagan Pugazhendhi, R Hari Krishna Raj and A Arun. (2022). Green nanotechnology for the environment. Handbook of Microbial Nanotechnology. In.: C. M. Hussain, editors. Elsevier Inc. DOI: https://doi.org/10.1016/B978-0-12-823426-6.00006-1
G. Sivaprakash, R. Karthik Raja, K. Mohanrasu, G.H. Dinesh and A. Arun. (2022). Microbial nanotechnology in food industry: antimicrobial packaging. Handbook of Microbial Nanotechnology. In.: C. M. Hussain, editors. Elsevier Inc. DOI: https://doi.org/10.1016/B978-0-12-823426-6.00002
Aiswarya D, Balasubramanian V., Raja M., Perumal P., Sivaramakrishnan S., Karthik Raja R. (2014). Entomopathogenic Nematodes for the Control of Insect Pests. In: Sivaramakrishnan, S. Ilangovan. A. and Karthik Raja. R. A. editors. Advances in Biotechnology and Patenting, Elsevier Publishing, 49-55.
R. Karthik Raja, R. Ramkumar, M. Kavitha, D. Aiswarya, M. Raja (2014). Prevalence of Eustrongylides sp. (Nematoda: Dioctophymatoidea) Infection in Catfish Fish Sperta aor (Hamilton, 1822) from Stanley Reservoir, Tamil Nadu. In: Sivaramakrishnan, S. Ilangovan. A. and Karthik Raja. R. A. editors. Advances in Biotechnology and Patenting, Elsevier Publishing, 117-123.
P. Palaniappan, R. Anandham, S. Saravanan, S. Sood, A. Gulati, S. Sivaramakrishnan, R. Karthik Raja, T. Sa (2014). Isolation, Biochemical Characterization and Nodulation Efficiency of Bradyrhizobium, Rhizobium and other Endophytic Bacterial Strains Recovered from Lespedeza sp. of South Korea. In: Sivaramakrishnan, S. Ilangovan. A. and Karthik Raja. R. A. editors. Advances in Biotechnology and Patenting, Elsevier Publishing, 187-204.
Books Edited
Books Edited
Sivaramakrishnan, S. Ilangovan. A. and Karthik Raja. R. (2014). Advances in Biotechnology and Patenting. Elsevier Publishing. ISBN:9789351073079.
Sivaramakrishnan, S. and Karthik Raja. R. (2014). Conservation of Biodiversity Using Biotechnological Approaches. Elsevier Publishing. ISBN: 9789351073062.
Publications
C. Selvaraj, R. Karthik Raja, D. Velmurugan and Sangeev Kumar Sing. (2022). Transcriptional regulatory mechanisms and signaling netwoks in cancer. Advances in Protein Chemistry and Structural Biology. (Accepted) (Impact Factor: 5. 447)
C. Selvaraj, U. Panwar, R. Karthik Raja, R. Vijayakumar, and S. Kumar Singh. (2022). Exploring the macromolecules for secretory pathway in cancer disease, Advances in Protein Chemistry and Structural Biology, https://doi.org/10.1016/bs.apcsb.2022.10.003. (Impact Factor: 5. 447)
A. Priya, A. Selvaraj, D. Divya, R. Karthik Raja and S. Karutha Pandian. (2021). In Vitro and In Vivo Anti-infective Potential of Thymol against Early Childhood Caries Causing Dual Species Candida albicans and Streptococcus mutans. Front. Pharmacol. 12:760-768. (Impact Factor: 5. 988)
Arul D., Balasubramanian V., Balasubramani G., Karthik Raja R., Aiswarya D. and Perumal P. (2022). Isolation of a bacterial strain from the gut of the fsh, Systomus sarana, identifcation of the isolated strain, optimized production of its protease, the enzyme purifcation, and partial structural characterization. Journal of Genetic Engineering and Biotechnology. https://doi.org/10.1186/s43141-022-00299-3.
A. Pugazhendhi, S. Vasantharaj, S. Sathiyavimal, R. Karthik Raja, I. Karuppusamy, M. Narayanan, S. Kandasamy, K. Brindhadevi. (2021). Organic and inorganic nanomaterial coatings for the prevention of microbial growth and infections on biotic and abiotic surfaces. Surface and Coatings Technology, 425, 127739. (Impact Factor: 4.865)
R. Karthik Raja, P. Nguyen-Tri, G. Balasubramani, A. Arun, S. Hazir, S. Ladhari, A. Saidi, A. Pugazhendhi, A. Anthoni Samy. (2021). SARS-CoV-2 and its new Variants: A Comprehensive Review on Nanotechnological Application Insights into Potential Approaches. Applied Nanoscience. https://doi.org/10.1007/s13204-021-01900-w. (Impact Factor: 3.869)
R. Karthik Raja, A. Arun, M. Touray, S.H. Gulsen, H. Cimen, B. Gulcu, C. Hazir, D. Aiswarya, D. Ulug, I. Cakmak, H. K. Kaya, S. Hazir. (2021). Antagonists and defense mechanisms of entomopathogenic nematodes and their mutualistic bacteria. Biological Control. https://doi.org/10.1016/j.biocontrol.2020.104452. (Impact Factor: 3.857)
R. S. Murugan, G. H. Dinesh, R. K. Raja, E. S. J. Obeth, A. Bora, N. M. Samsudeen, A. Pugazhendhi, A.Arun. (2020). Dark fermentative biohydrogen production by Acinetobacter junii-AH4 utilizing various industry wastewaters. International Journal of Hydrogen Energy. 46, 11297-11304 (Impact Factor: 7.139).
D. Aiswarya, R. K. Raja, C. Kamaraj, G. Balasubramani, P. Deepak, D. Arul, V. Amutha, C. Sankaranarayanan, S. Hazir, P. Perumal. (2019). Biosynthesis of Gold and Silver Nanoparticles from the Symbiotic Bacterium, Photorhabdus luminescens of Entomopathogenic Nematode: Larvicidal Properties against Three Mosquitoes and Galleria mellonella Larvae. Journal of Cluster Science. doi.org/10.1007/s10876-019-01564-1. (Impact Factor: 3.447).
D. Aiswarya, R. Karthik Raja, C. Kamaraj, G. Balasubramani, P. Deepak, D. Arul, P. Perumal (2018). Isolation and growth inhibition potential of entomopathogenic nematodes against three public health important mosquito vectors. Experimental Parasitology. 197, 76-84. (Impact Factor: 2.132).
Balasubramani, G., P. Deepak, D. Aiswarya, R. Karthik Raja, C. Kamaraj & P. Perumal (2018). Multipurpose efficacy of the lyophilized cell-free supernatant of Salmonella bongori isolated from the freshwater fish, Devario aequipinnatus: toxicity against microbial pathogens and mosquito vectors. Environmental Science and Pollution Research. doi:10.1007/s11356-018-2838-9. (Impact Factor: 5.190).
Lalitha K, Karthi S, Vengateswari G, Karthikraja R, Perumal P, Shivakumar M.S. (2018). Effect of entomopathogenic nematode of Heterorhabditis indica infection on immune and antioxidant system in lepidopteran pest Spodoptera litura (Lepidoptera: Noctuidae). Journal of Parasitic Diseases, https:/doi.org/10.1007/s12639-018-0983-1.
Raja, M., R. Karthik Raja, C. Kamaraj, V. Balasubramanian, M. Kavitha & P. Perumal (2018). The first report of an alien parasitic nematode, Camallanus cotti isolated from the wild Giant danio fish, Devario aequipinnatus, (Teleostei: Cyprinidae) from southern part of Western Ghats, India. Iranian Journal of Ichthyology. 5(3): 250-256.
R. Karthik Raja, S. Sivaramakrishnan, S. Hazir. (2011). Ecological characterization of Steinernema siamkayai (Rhabditida: Steinernematidae), a warm-adapted entomopathogenic nematode isolate from India. BioControl, 56: 789 - 798. (Impact Factor: 3.571).
R. Karthik Raja, D. Aiswarya, B. Gulcu, M. Raja, P. Perumal, S. Sivaramakrishnan, H. K. Kaya, S. Hazir (2017). Response of three cyprinid fish species to the Scavenger Deterrent Factor produced by the mutualistic bacteria associated with entomopathogenic nematodes. Journal of Invertebrate Pathology, 143: 40–49. (Impact Factor: 2.841).
Baris Gulcu, Harun Cimen, Ramalingam Karthik Raja, Selcuk Hazir (2017). Entomopathogenic Nematodes and their Mutualistic Bacteria: Their Ecology and Application as Microbial Control Agents. Biopesticide International, 13(2):79-112.
R. Ramkumar, G. Balasubramani, R. Karthik Raja, M. Raja, R. Govindan, E. K. Girija, P. Perumal (2017). Lantana camara Linn root extract mediated gold nanoparticles and their in vitro antioxidant and cytotoxic potentials. Artificial Cells, Nanomedicine, and Biotechnology. DOI:10.1080/21691401.2016.1276923. (Impact Factor: 6.355).
C. Kamaraj, G. Balasubramani, C. Siva, M. Raja, V. Balasubramanian, R. Karthik Raja, S. Tamilselvan, G. Benelli, P. Perumal (2017). Ag Nanoparticles Synthesized Using b-Caryophyllene Isolated from Murraya koenigii: Antimalarial (Plasmodium falciparum 3D7) and Anticancer Activity (A549 and HeLa Cell Lines). Journal of Cluster Sciences, DOI 10.1007/s10876-017-1180-6. (Impact Factor: 3.447).
Kavitha, M., M. Raja, C. Kamaraj, R. Karthik Raja, V. Balasubramaniam, G. Balasubramani & P. Perumal (2017). In vitro Antimicrobial Activity of Azadirachta indica (Leaves) against Fish Pathogenic Bacteria Isolated from Naturally Infected Dawkinsia filamentosa (Blackspot barb). Medicinal & Aromatic Plants (Los Angels), (6)3 DOI: 10.4172/2167-0412.1000294.
G. Balasubramani, R. Ramkumar, R. Karthik Raja, D. Aiswarya, C. Rajthilak, P. Perumal (2016). Albizia amara Roxb. Mediated Gold Nanoparticles and Evaluation of Their Antioxidant, Antibacterial and Cytotoxic Properties. Journal of Cluster Sciences, DOI 10.1007/s10876-016-1085-9. (Impact Factor: 3.447).
M. Raja, R. Karthik Raja, R. Ramkumar, M. Kavitha, D. Aiswarya, P. Deepak, P. Perumal (2016). First report on the occurrence of abnormal vertebrate containing Giant Danio-fish, Devario aequipinnatus (McClelland, 1839) in Stanley Reservoir of Cauvery River, Tamil Nadu (India). International Journal of Fisheries and Aquatic Studies, 4(3): 528-531.
M. Raja, R. Karthik Raja and P. Perumal (2016). Zebrafish in the Wild: Microhabitat Use by Zebrafish Danio rerio (Hamilton, 1822) from Karala River of Jalpaiguri District, Northern Bengal, India. Fisheries and Aquaculture Journal, Doi:10.4172/2150-3508.1000179.
R. Karthik Raja, C. Hazir, A. Gumuş, C. Asan, M. Karagoz, S. Hazir (2015). Efficacy of the entomopathogenic nematode Heterorhabditis bacteriophora using different application methods in the presence or absence of a natural enemy. Turkish Journal of Agriculture and Forestry, 39: 277-285. (Impact Factor: 2.669).
R. Karthik Raja, R. Anupriya, D. Aiswarya, M. Raja, V. Balasubramanian, M. Anandhi. S. Sivaramakrishnan, P. Perumal (2015). A Survey for Entomopathogenic Nematodes in Agricultural Fields of Karuppur Area, Salem District, Tamil Nadu, India. International Journal of Pure and Applied Biotechnology, 2; 24-28.
V. Balasubramanian, R. Kamalakkannan M. Raja, R. Karthik Raja, P. Perumal (2015). Exploration of HDPE degradation by immobilized Aspergillus terreus. International Journal of Pure and Applied Biotechnology, 2: 35-48.
M. Raja, R. Ramkumar, M. Kavitha, V. Balasubramanian R. Karthik Raja, M. Anandhi, P. Perumal (2015). Ichthyofauna diversity with relation to water quality and habitat characteristics of Krishnagiri Reservior, Tamil Nadu, India. International Journal of Pure and Applied Biotechnology, 2: 1-8.
Karthik Raja R, Razia M, Chellapandi P, Sivaramakrishnan S. (2012). Survey and assessment of soil nematodes in Tsunami impacted agricultural areas of South India. Journal of Advances in Developmental Research, 3(1): 40-44.
Razia M, Karthik Raja R, Chellapandi P, Sivaramakrishnan (2012). Evaluating Heavy metal stress responses of entomopathogenic nematode Steinernema glaseri in the agro-ecosystem of Tamil Nadu. Journal of Advances in Developmental Research, 3(1):49-51.
Razia M, Padmanaban K, Karthik Raja R, Chellapandi P and Sivaramakrishnan S (2011). PCR-RFLP pattern analysis of entomopathogenic nematodes isolated from agro-ecosystem for implicating their genetic diversity. Munis Entomology & Zoology, 6(1): 404- 411.
Razia M, Padmanaban R, Karthik Raja R, Chellapandi P, Sivaramakrishnan S. (2011). Monitoring entomopathogenic nematodes as ecological indicators in the cultivated lands of Karur District, Tamil Nadu: a survey report. Electronic Journal of Biology, 7(1): 16-19.
Razia M, Karthik Raja R, Padmanaban K, Chellapandi P and Sivaramakrishnan S (2011). 16S rDNA-based phylogeny of non-symbiotic bacteria associating entomopathogenic nematode from infected insect cadavers. Genomics, Proteomics and Bioinformatics. 9(3): 104-112. (Impact Factor: 7.691).
Karthik Raja R, Ramesh N, Maripandi A. (2010). Invasion and interaction studies of Salmonella typhimurium subsp. enteritis in Vero and MDCK cell lines. Advances in Biological Research, 4 (2): 86-91.
Razia M, Karthik Raja R, Padmanaban K, Sivaramakrishnan S and Chellapandi P. (2010). A phylogenetic approach for assigning function of hypothetical proteins in Photorhabdus luminescens subsp. laumondii TT01 genome. Journal of Computer Science and Systems Biology, 3(1): 021-029.
Ramesh N, Rajesh Kannan V, Karthikeyan K, Nanthakumar K and Karthik Raja R. (2009). Sero diagnosis of Bluetongue virus infection and isolation of virus in embryonated chicken egg and BHK-21 cell line. Research Journal of Microbiology, 4 (5): 186 –193.
Professional activities:
Professional activities:
Invited presentations/lectures
Invited presentations/lectures
R. Karthik Raja, D. Aishwarya, S. Sivaramakrishnan, S. Hazir and P. Perumal. (2015). Ecological characterization of Steinernema siamkayai (Rhabditida: Steinernematidae), a warm-adapted entomopathogenic nematode isolate from India in International Congress on Invertebrate Pathology & Microbial Control and the 48th Annual Meeting of the Society for Invertebrate Pathology
D. Aiswarya, V. Devi, R. Karthik Raja, M. Raja, V. Balasubramaniam, C. Kamaraj, G. Balasubramani, P. Perumal (2016). Efficacy of three entomopathogenic nematode species against mosquito larvae Aedes aegypti (Diptera: Culicidae) in International conference on Current Trends in Biotechnology.
M. Razia, R. Karthik Raja, K. Padmanaban, S. Sivaramakrishnan, and P. Chellapandi. (2010). Functional Annotation of Hypothetical Proteins in Photorhabdus luminescens subsp. laumondi TT01 Genome in International Conference on Climate Change and Bioresource
Karthik Raja. R, Selcuk HAZIR and Sivaramakrishnan. S (2009). A survey for Entomopathogenic nematodes in Tiruchirappalli District of Tamil Nadu in Second International Entomopathogen and Microbial Control Symposium
R. Karthik Raja, M. Razia and S. Sivaramakrishnan (2008). Photorhabdus sp. (BDU1) (Enterobacteriaceae) suspension against plant pathogenic bacteria in National Symposium on Current Scenario in Microbial technology
R. Karthik Raja, S. Sivaramakrishnan, K. Padmanaban, G. Seghal Kiran and M. Razia. (2007). Effect of metal ions on survival and pathogenicity of Steinernema carpocapsae in the laboratory in International Conference on Biotechnological Approaches in Bioresource Management
M. Razia, S. Sivaramakrishnan, R. Karthik Raja and K. Padmanaban. (2007). Neem enhances the persistence and infectivity of Steinernema carpocapsae in the pesticide and fertilizer toxicity against Holotrica serrata in sugarcane field in International Conference on Biotechnological Approaches in Bioresource Management
R. Karthik Raja, A. Maripandi, U. Balamuralikanth and P. Sasikumar. (2004). Characterization of Xylanase produced by Bacillus subtillus in Biorevolutions, 04.
Memberships of Professional Societies
Membership in Society of Invertebrate Pathology
Membership in Nematological Society of India
Member in Society of Nematologists, USA
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