The Cell stress and Cancer group is focused on two main goals:
to understand how autophagy is switched off in vivo and
to unravel mechanisms of autophagy involvement in cancer biology.
We make use of model organisms as well as primary material from cancer patients to study several basic problems in autophagy and cancer.
Understand how autophagy termination is regulated and how this affects the development and fitness of the organism, as well as the implications for cancer.
Understand nutrient signaling pathways such as autophagy in various forms of renal cancer with the aim of identifying biomarkers and developing novel forms of treatment.