Selected publications
Li C., Xie S., Wang J., Sharvia S., Chan K.Y., SC-Track: a robust cell-tracking algorithm for generating accurate single-cell lineages from diverse cell segmentations, Briefings in Bioinformatics, Volume 25, Issue 3, May 2024, bbae192, https://doi.org/10.1093/bib/bbae192
Gui Y., Xie S., Wang Y., Wang P., Yao R., Gao X., Dong Y., Wang G., Chan K.Y., pcnaDeep: a fast and robust single-cell tracking method using deep-learning mediated cell cycle profiling, Bioinformatics, 2022;, btac602. https://doi.org/10.1093/bioinformatics/btac602
Lin, M., Xie, S.S. & Chan, K.Y. An updated view on the centrosome as a cell cycle regulator. Cell Div 17, 1 (2022). https://doi.org/10.1186/s13008-022-00077-0
Chan KY1, Alonso-Nunez ML, Grallert A, Tanaka K, Connolly Y, Smith DL, Hagan IM1 (2017), Dialogue between the centrosomal entrance and exit scaffold pathways regulates mitotic commitment. Journal Cell Biology. 216(9):2795-2812. 1Author of correspondence
Special commentary: Ben Short; J Cell Biol 4 September 2017; 216 (9): 2599. doi: https://doi.org/10.1083/jcb.201708080
Commented in: Oakley B: Faculty Opinions Recommendation, In Faculty Opinions, 22 Aug 2017; https://doi.org/10.3410/f.727874365.793535481
Grallert A2, Chan KY2, Alonso-Nunez ML, Madrid M, Biswas A, Alvarez-Tabares I, Connolly Y, Tanaka K, Robertson A, Ortiz JM, Smith DL, Hagan IM (2013), Removal of centrosomal PP1 by NIMA kinase unlocks the MPF feedback loop to promote mitotic commitment in S. pombe. Current Biology. 23(3):213-22. 2Contributed equally
Special commentary: Meadows JC, Millar JB. Curr Biol. 2013 Feb 4;23(3):R120-2. https://doi.org/10.1016/j.cub.2012.12.020
Grallert A, Patel A, Tallada VA, Chan KY, Krapp A, Simanis V, Hagan IM (2013), Centrosomal MPF triggers the mitotic and morphogenetic switches of fission yeast. Nature Cell Biology. 15(1):88-95. https://doi.org/10.1038/ncb2633
Chan KY, Matthews K, Ersfeld K (2010), Functional characterisation and drug target validation of a mitotic Kinesin-13 in Trypanosoma brucei. PLoS Pathogens. 6:e1001050. https://doi.org/10.1371/journal.ppat.1001050
Chan KY, Ersfeld K (2010), The role of the Kinesin-13 family protein TbKif13-2 in flagellar length control of Trypanosoma brucei. Molecular Biochemical Parasitology. 174(2):137-40. https://doi.org/10.1016/j.molbiopara.2010.08.001