In its 2013 expert consensus statement on inherited primary arrhythmia syndromes, the Heart Rhythm Society/European Heart Rhythm Association/Asia Pacific Heart Rhythm Society (HRS/EHRA/APHRS) indicated catecholaminergic polymorphic ventricular tachycardia (CPVT) can be diagnosed when any for the following criteria are met:
Structurally normal heart, normal electrocardiogram (ECG), and unexplained exercise or catecholamine-induced bidirectional VT or polymorphic ventricular premature beats (VPBs) or VT in an individual younger than 40 years
Presence of a pathogenic mutation
Family history of CPVT with a normal heart, exercise-induced premature ventricular contractions or bidirectional/polymorphic VT
Structurally normal heart and coronary arteries, normal ECG, and unexplained exercise or catecholamine-induced bidirectional VT or polymorphic VPBs or VT in an individual older than 40 years