Publications

Mitochondrial alterations in fibroblasts from sporadic Alzheimer's disease (AD) patients correlate with AD-related clinical hallmarks  F.Eysert, P.-F. Kinoshita, J.Lagarde, S.Lacas-Gervais, L.Xicota, G.Dorothée, M.Bottlaender, F.Checler, M.-C.Potier, M.Sarazin & M.Chami, Acta Neuropathologica Communications volume 12, Article number: 90 (June 8th 2024)

Bax Inhibitor-1 preserves pancreatic β-cell proteostasis by limiting proinsulin misfolding and programmed cell death – M. Blanc, L.Habbouche, P.Xiao, C.Lebeaupin, M.Janona, N.Vaillant, M.Irondelle, J.Gilleron, F.Murcy, D.Rousseau, C.Luci, T.Barouillet, S.Marchetti, S.Lacas-Gervais, L.Y.-Charvet, P.Gual, A. K. Cardozo, B.Bailly-Maitre Cell Death Dis 15, 334 (2024, May). https://doi.org/10.1038/s41419-024-06701-x

The Phytophthora parasitica effector AVH195 interacts with ATG8, attenuates host autophagy, and promotes biotrophic infection. S.Testi, M.-L.Kuhn, V.Allasia, P.Auroy, F.Kong, G.Peltier, S.Pagnotta, J.Cazareth, H.Keller & F. Panabières BMC Biol 22, 100 (2024). https://doi.org/10.1186/s12915-024-01899-w

A Potent Solution for Tumor Growth and Angiogenesis Suppression via an ELR+CXCL-CXCR1/2 Pathway Inhibitor O.Grytsai, M.Dufies, J.Le Du, O.Rastoin, L.C.Pires Gonçalves, L.Mateo, S.Lacas-Gervais, Y.Cao, L.Demange, G.Pagès, R.Benhida, C. Ronco ACS Medicinal Chemistry Letters Article ASAP (2024, April) DOI:10.1021/acsmedchemlett.4c00053

Golgi-associated retrograde protein (GARP) complex-dependent endosomes to trans Golgi network retrograde trafficking is controlled by Rab4b. Gilleron J, Chafik A, Lacas-Gervais S, Tanti JF, Cormont M. Cell Mol Biol Lett. 2024 Apr 16;29(1):54

A mechanical wave travels along a genetic guide to drive the formation of an epithelial furrow during Drosophila gastrulation. Popkova A, Andrenšek U, Pagnotta.S, Ziherl P, Krajnc M, Rauzi M.Dev Cell. 2024 Jan 15 : S1534-5807(23)00694-9. doi: 10.1016/j.devcel.2023.12.016.

Exploring uranium bioaccumulation in the brown alga Ascophyllum nodosum: insights from multi-scale spectroscopy and imaging. Zerbini M, Solari PL, Orange.F, Jeanson A, Leblanc C, Gomari M, Auwer CD, Beccia MR.Sci Rep. 2024 Jan 10;14(1):1021. doi: 10.1038/s41598-023-49293-w.

Defects in AMPAR trafficking and microglia activation underlie socio-cognitive deficits associated to decreased expression of phosphodiesterase 2 a. Delhaye S, Jarjat M, Boulksibat A, Sanchez C, Tempio A, Turtoi A, Giorgi M, Lacas-Gervais S, Baj G, Rovere C, Trezza V, Pellegrini M, Maurin T, Lalli E, Bardoni B. Neurobiol Dis. 2023 Dec 26;191:106393. doi: 10.1016/j.nbd.2023.106393. 

Directional formation of microtubes by soft-template electropolymerization from fully conjugated triphenylamine-based monomers K.Diouf, A.Dramé, A.Diouf, F.Orange, F.Guittard, I.F. Perepichka, T. Darmanin Journal of Electroanalytical Chemistry,Volume 946, 1 October 2023, 117747, ISSN 1572-6657

Conversion of Lavandula Straw into High-Quality Solid Fuel: Effect of Hydrothermal Carbonization Conditions on Fuel Characteristics. Li, X., Baran, S. S., Orange.F., Bonjour, E., Jame, P., Verger-Dubois, G., Mija, A., Lomenech, C., Kuzhir, P., Hurel, C. (2023, July 26). BioEnergy Research, 16(2), 1156-1172.

Environment and Plant Use at La Tourasse (South-West France) at the Late Glacial–Holocene Transition Liard, A, Varea C M M, Orange.F. Huot J.P. Marquebielle B Henry A. Open Archaeology, vol. 9, no. 1, July 2023, pp. 20220292.

YbPO4 crystals in as-drawn silica-based optical fibers Z.Lu, N.Vakula, M.Ude, M.Cabié, T.Neisius, F.Orange, F. Pigeonneau, L.Petit, W.Blanc, Optical Materials,Volume 138, April 2023,113644, ISSN 0925-3467

Recyclable, Repairable, and Fire-Resistant High-Performance Carbon Fiber Biobased Epoxy R.Dinu, U.Lafont, O.Damiano, F.Orange, Al.Mija ACS Applied Polymer Materials 20 March 2023 5 (4), 2542-2552

Expedient and efficient: An Early Mesolithic composite implement from Krzyż Wielkopolski Kabaciński, J., Henry, A., David, É, Rageot, M., Cheval, C., Winiarska-Kabacińska, M., Orange.F. (2023.02.02).. Antiquity, 97(392), 295-313 

Conserved meiotic mechanisms in the cnidarian Clytia hemisphaerica revealed by Spo11 knockout. Munro C, Cadis H, Pagnotta.S, Houliston E, Huynh JR. Sci Adv. 2023 Jan 27;9(4):eadd2873. doi: 10.1126/sciadv.add2873.

VAP-A intrinsically disordered regions enable versatile tethering at membrane contact sites. Subra M, Dezi M, Bigay J, Lacas-Gervais S, Di Cicco A, Araújo ARD, Abélanet S, Fleuriot L, Debayle D, Gautier R, Patel A, Roussi F, Antonny B, Lévy D, Mesmin B. Dev Cell. 2023 Jan 23;58(2):121-138. 

From macrotraces to micro-tomography: a multi-scale approach for detecting and characterising the “Spiralled Patchwork Technology” in Northern Mediterranean Neolithic pottery assemblages. L. Gomart, D. Binder, L. Blanc-Féraud, L. Cassard, S. Cohen, V. L. Coli, M. Gabriele, J. Leblond, F.Orange, D. Pisani, S. Sorin. Céramiques imprimées de Méditerranée occidentale (VIe millénaire AEC): données, approches et enjeux nouveaux/Western Mediterranean Impressed Wares (6th millennium BCE): new data, approaches and challenges, Actes de la Séance de la Société préhistorique française, Nice, 18-20 mars 2019.

Harsh intertidal environment enhances metabolism and immunity in oyster (Crassostrea gigas) spat Corporeau C, Petton S, Vilaça R, Delisle L, Quéré C, Le Roy V, Dubreuil C, Lacas-Gervais S, Guitton Y, Artigaud S, Bernay B, Pichereau V, Huvet A, Petton B, Pernet F, Fleury E, Madec S, Brigaudeau C, Brenner C, Mazure NM, 2022 Sep

Holocene marine tephra offshore Ecuador and Southern Colombia: First trench-to-arc correlations and implication for magnitude of major eruptions. M.Bablon, G. Ratzov, F. Nauret, P.Samaniego, F.Michaud, M.Saillard, J-N.Proust, J-L.Le Pennec, J-Y.Collot, J-L.Devidal, F.Orange, C.Liorzou, S.Migeon, S.Vallejo, S.Hidalgo, P.Mothes, M.Gonzalez. Geochemistry, Geophysics, Geosystems 2022 Sept 06 e2022GC010466

Autophagy inactivation in osteosarcoma leads to the appearance of poor prognosis-associated factors. O. Camuzard, M. Nollet, S. Santucci-Darmanin, M-C. Trojani, N. Ben Abderrahman, V. Virolle, F. Burel-Vandenbos, S.Pagnotta, F.Orange, E. Kolano-Merlin, G. F Carle, V. Pierrefite-Carle. Autophagy Reports, 2022 Sept : 1, 418-437

Conversion of Lavandula Straw into High-Quality Solid Fuel: Effect of Hydrothermal Carbonization Conditions on Fuel Characteristics Li, X., Baran, S.S., Orange.F. et al. 2022 July 26 Bioenerg. Res. 

Unravelling the sex-specific diversity and functions of adrenal gland macrophages. Dolfi B, Gallerand A, Firulyova MM, Xu Y, Merlin J, Dumont A, Castiglione A, Vaillant N, Quemener S, Gerke H, Stunault MI, Schrank PR, Kim SH, Zhu A, Ding J, Gilleron J, Magnone V, Barbry P, Dombrowicz D, Duranton C, Wakkach A, Blin-Wakkach C, Becher B, Pagnotta.S, Argüello RJ, Rantakari P, Chakarov S, Ginhoux F, Zaitsev K, Kim KW, Yvan-Charvet L, Guinamard RR, Williams JW, Ivanov S.Cell Rep. 2022 Jun 14;39(11):110949.

CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability Genin EC, Bannwarth S, Ropert B, Lespinasse F, Mauri-Crouzet A, Augé G, Fragaki K, Cochaud C, Donnarumma E, Lacas-Gervais S, Wai T, Paquis-Flucklinger V. Brain. 2022 Jun 3

Coordination of two opposite flagella allows high-speed swimming and active turning of individual zoospores. Tran QD, Galiana E, Thomen P, Cohen C, Orange.F, Peruani F, Noblin X. Elife. 2022 Mar 28;11:e71227. 

Tunable Nanoporous Structures with Rose Petal Effect by Soft-Template Electropolymerization of Benzotrithiophene Monomers. S.Sow, S.Dihissou, A.Dramé, A.Sene, F.Orange, S.Yandé Dieng, F.Guittard, T.Darmanin. ChemistrySelect 2022 Mar 16,7,  e20220035

Plasma Membrane Phosphatidylinositol-4-Phosphate Is Not Necessary for Candida albicans Viability yet Is Key for Cell Wall Integrity and Systemic Infection. R.Garcia-Rodas, H. Labbaoui, F.Orange, N.Solis, O. Zaragoza, S.G. Filler, M.Bassilana, R.A.Arkowitz, Eukaryotics Cells, 2022 February 15. 

Identification of Small Molecules Inhibiting Cardiomyocyte Necrosis and Apoptosis by Autophagy Induction and Metabolism Reprogramming. Liu D, Peyre F, Loissell-Baltazar YA, Courilleau D, Lacas-Gervais S, Nicolas V, Jacquet E, Dokudovskaya S, Taran F, Cintrat JC, Brenner C.. Cells. 2022 Jan 29;11(3):474.

Effect of Electrolyte Nature on Micellar Soft-Template Electropolymerization in Organic Solvent to Form Nanoporous Polymer Films with a Bioinspired Strategy. Fradin, C., Orange, F, Amigoni, S. et al. Effect of Electrolyte Nature on Micellar Soft-Template Electropolymerization in Organic Solvent to Form Nanoporous Polymer Films with a Bioinspired Strategy. J Bionic Eng 2022 Jan 28.

Conversion of Biomass-Derived Methyl Levulinate to Methyl Vinyl Ketone F.El Ouahabi, W.Smit, C.Angelici, M.Polyakov, U.Rodemerck, C.Fischer, V. Narayana Kalevaru, S.Wohlrab, S.Tin, G.P. M. van Klink, Jan C. van der Waal, F.Orange, and J.G. de Vries ACS Sustainable Chemistry & Engineering 2022 Jan 3, 766-775 

A Humins-Derived Magnetic Biochar for Water Purification by Adsorption and Magnetic Separation C Lomenech, C Hurel, L Messina, M Schembri, P Tosi, F. Orange, F. Georgi, A.Mija, P. Kuzhir, Waste and Biomass Valorization 2021 ; 12 (12), 6497-6512. 

Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation. J. Merlin , S. Ivanov, A. Dumont, A. Sergushichev , J. Gall, M. Stunault, M. Ayrault, N. Vaillant , A. Castiglione, A. Swain, F. Orange, A. Gallerand, T. Berton, JC. Martin, S. Carobbio, J. Masson, I. Gaisler-Salomon, P. Maechler, S. Rayport, J. C Sluimer, EAL Biessen, RR Guinamard, EL Gautier, EB Thorp, MN Artyomov, L. Yvan-Charvet ; Nat Metab ; 2021 Oct;3(10):1313-1326. 

40Ar/39Ar dating of high temperature geothermal systems: First attempt on hydrothermally altered pyroxenes from the Saintes archipelago (Lesser Antilles arc, Guadeloupe) A. Favier, C. Verati, J-M. Lardeaux, P. Münch, C. Renac,  M. Corsini, F. Orange Chemical Geology, Elsevier, 2021 October 21, 581, pp.120401.

Holocene East African monsoonal variations recorded in wave-dominated clastic paleo-shorelines of Lake Abhe, Central Afar region (Ethiopia & Djibouti) C. Mologni, L. Bruxelles, M. Schuster, G. Davtian, C.Ménard, F.Orange, C.Doubre, J. Cauliez, H.Berhane Taezaz, M.Revel, L. Khalidi, Geomorphology, Volume 391,2021 October 15, 107896.

Prehispanic fuel management in the Canary Islands: A new experimental dataset for interpreting Pinus canariensis micromorphological degradation patterns on archeological charcoal P. Vidal-Matutano, A.Henry, A. Carré, F.Orange, I. Théry-Parisot, Review of Palaeobotany and Palynology, September 30th 2021, 104537, ISSN 0034-6667

The stereomicroscope and scanning electron microscope comparison of false starts bones produced by an oscillating autopsy saw C. Bernardi, L.Nogueira, F.Orange, G. F.Carle, V. Alunni, G.Quatrehomme, Forensic Science International Volume 324, July 2021, 110816 

Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology W. El Manaa, E. Duplan, T. Goiran, I. Lauritzen, L. Vaillant Beuchot, S. Lacas-Gervais, V. A. Morais, H.You, L. Qi, M. Salazar, U. Ozcan, M. Chami, F. Checler & C. Alves da Costa 2021 may 24

Micellar formation by soft template electropolymerization in organic solvents  C.Fradin, F.Orange, S.Amigoni, C.R.Szczepanski, F.Guittard, T.Darmanin Journal of Colloid and Interface Science Volume 590, 15 May 2021, Pages 260-267

Reprocessable humins thermosets and composites R.Dinu, S.Montes, F. Orange, A. Mija Composites Science and Technology Volume 207, 3 May 2021, 108655 

 UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling S.Torrino , V. Tiroille, B. Dolfi, M. Dufies, C. Hinault, L. Bonesso, S. Dagnino, J. Uhler, M. Irondelle, A-S. Gay, L. Fleuriot, D. Debayle, S.Lacas-Gervais, M.Cormont, T. Bertero, F. Bost, J.Gilleron, S. Clavel, eLife 2021 april 22 ;10:e6834

Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain A.Valverde,  J.Dunys, T. Lorivel, D.Debayle,  A-S. Gay,  S.Lacas-Gervais, B.Roques, M.Chami,  F.Checler  Acta Neuropathologica, Springer Verlag, 2021 april  21, 141 (6), pp.823-839.

EFA6A, an exchange factor for Arf6, regulates early steps in ciliogenesis M.Partisani, C. Baron, R. Ghossoub, R. Fayad, S.Pagnotta, Lacas-Gervais S et al.. Journal of Cell Science, Company of Biologists, 2021 april 19, 134 (2), pp.jcs249565.

Identification of adipocytes as target cells for Leishmania infantum parasites. Schwing A, Pisani DF, Pomares C, Majoor A, Lacas-Gervais S, Lemichez E, Marty P, Boyer L, Michel G Research Square; 2021 March 13

Densely packed open microspheres by soft template electropolymerization of benzotrithiophene-based monomers Y.Levieux-Souid, A.Sathanikan, F. Orange, F.Guittard, T.Darmanin. Electrochimica Acta volume 369, 10 February 2021, 137677

How to highlight slash-and-burn agriculture in ancient soils? A modern baseline of agrarian fire imprint in the Guatemalan lowlands using charcoal particle analysis  L. Dussol, B. Vannière, L.Purdue,  F. Orange, M.Testé, C. Castanet, A. Garnier, E. Lemonnier, I. Théry-Parisot,  Journal of Archaeological Science: Reports, Elsevier, 2021 Frebuary, 35, pp.102725.

Low doses of uranium and osteoclastic bone resorption: key reciprocal effects evidenced using new in vitro biomimetic models of bone matrix T.Gritsaenko, V.PierrefiteCarle, G.Creff,  B.Simoneau, A.Hagège, D.Farlay, S.Pagnotta, F.Orange, X. Jaurand, C.Den Auwer, G.Carle, S. Santucci-Darmanin. Arch Toxicol 95, 1023–1037(2021, January 11). 

Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer's disease models and human brains Vaillant-Beuchot L, Mary A, Pardossi-Piquard R, Bourgeois A, Lauritzen I, Eysert F, Kinoshita PF, Cazareth J, Badot C, Fragaki K, Bussiere R, Martin C, Mary R, Bauer C, Pagnotta S, Paquis-Flucklinger V, Buée-Scherrer V, Buée L, Lacas-Gervais S, Checler F, Chami M. Acta Neuropathol. 2021 Jan;141(1) 

Autophagy in Osteosarcoma Cancer Stem Cells Is Critical Process which Can Be Targeted  by the Antipsychotic Drug Thioridazine O. Camuzard , M-C Trojani , S. Santucci-Darmanin, S. Pagnotta, V. Breuil , G. F. Carle 1 and V. Pierrefite-Carle , Cancers 2020 Dec 07 12, 3675

Evidences of a Direct Relationship between Cellular Fuel Supply and Ciliogenesis Regulated by Hypoxic VDAC1-ΔC. Meyenberg Cunha-de Padua M, Fabbri L, Dufies M, Lacas-Gervais S, Contenti J, Voyton C, Fazio S, Irondelle M, Mograbi B, Rouleau M, Sadaghianloo N, Rovini A, Brenner C, Craigen WJ, Bourgeais J, Herault O, Bost F, Mazure NM - Cancers (Basel) . 2020 Nov 23;12(11):E3484 

Bioinspired surfaces with strong water adhesion from electrodeposited poly(thieno[3,4-b]thiophene) with various branched alkyl chains O.Thiam, Alioune Diouf, F.Orange, S.Yandé Dieng, F.Guittard, T.Darmanin - Journal of Polymer Research volume 27, Article number: 360 (2020-November 07)

Frequency of exceptional Nile flood events as an indicator of Holocene hydro-climatic changes in the Ethiopian Highlands C.Mologni, M.Revel, C.Blanchet, D.Bosch, A-L Develle, F.Orange, L.Bastian, L.Khalidi, E.Ducassou, S.Migeon - Volume 247, 1 November 2020, 106543 

Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains  L.Vaillant-Beuchot, A.Mary, R.Pardossi-Piquard, Al.Bourgeois, I.Lauritzen, F.Eysert, P.Fernanda Kinoshita, J.Cazareth, C.Badot, K.Fragaki, R.Bussiere, C.Martin, R.Mary, C.Bauer, S.Pagnotta, V.Paquis-Flucklinger, V.Buée-Sherrer, Luc Buée, S.Lacas-Gervais, F.Checler, M.Chami -  Acta Neuropathologica 2020 October 20.

Influence of spacer in the formation of nanorings by templateless electropolymerization. F.Sow, A.Dramé, S.Sow, A.Sene, F.Orange, S.Y.Dieng, F.Guittard, T.Darmanin. Materials Today Chemistry, Vol 17, September 2020, 100278

Influence of alkyl spacer in nanostructure shape control by templateless electropolymerization. S.Sow, F.Sow, A. Dramé, F. Orange, A. Sene, S. Y. Dieng, F. Guittard,T. Darmanin, Progress in Organic Coatings, V. 146, September 2020.

Atypical Membrane-Anchored Cytokine MIF in a Marine Dinoflagellate. Jaouannet M, Pavaux AS, Pagnotta S, Pierre O, Michelet C, Marro S, Keller H, Lemée R, Coustau C. - Microorganisms. 2020 Aug 20;8(9):1263 

Fire and grass-bedding construction 200 thousand years ago at Border Cave, South Africa L.Wadley, I.Esteban, P.de la Peña,  M.Wojcieszak, D.Stratford, S.Lennox, F.d’Errico, D.Eugenia Rosso, F.Orange, L.Backwel, C.Sievers - Science Vol. 369, Issue 6505, pp. 863-866, 14 Aug 2020

Neural anatomy of echinoid early juveniles and comparison of nervous system organization in echinoderms L.Formery, F.Orange, A.Formery, S.Yaguchi, C. J. Lowe, M.Schubert, J. C. Croce - J Comp Neurol. 1–22,  2020 July 24 

Transcriptomic and Ultrastructural Signatures of K+-Induced Aggregation in Phytophthora parasitica Zoospores I.Bassani, C.Rancurel , S.Pagnotta, F.Orange , N.Pons ,K.Lebrigand , F.Panabières , L.Counillon , X.Noblin , E.Galiana - Microorganisms, 8(7), 1012, 2020 July 07.

Defined p16 High Senescent Cell Types Are Indispensable for Mouse Healthspan Grosse L, Wagner N, Emelyanov A, Molina C, Lacas-Gervais S, Wagner KD, Bulavin DV. Cell Metab. 2020 May 26:S1550-4131(20)30241-2.

Hepatic FNDC5 Is a Potential Local Protective Factor Against Non-Alcoholic Fatty Liver Canivet CM, Bonnafous S, Rousseau D, Leclere PS, Lacas-Gervais S, Patouraux S, Sans A, Luci C, Bailly-Maitre B, Iannelli A, Tran A, Anty R, Gual P. Biochim Biophys Acta Mol Basis Dis. 2020 May 1;1866(5):165705. 

REDD1 Deficiency Protects Against Nonalcoholic Hepatic Steatosis Induced by High-Fat Diet Dumas K, Ayachi C, Gilleron J, Lacas-Gervais S, Pastor F, Favier FB, Peraldi P, Vaillant N, Yvan-Charvet L, Bonnafous S, Patouraux S, Anty R, Tran A, Gual P, Cormont M, Tanti JF, Giorgetti-Peraldi S. FASEB J. 2020 Apr;34(4):5046-5060.

Solidago virgaurea L. Plant Extract Targeted Against Candida albicans to Reduce Oral Microbial Biomass: A Double Blind Randomized Trial on Healthy Adults Prêcheur I, Rolland Y, Hasseine L, Orange F, Morisot A, Landreau A. Antibiotics (Basel). 2020 Mar 25;9(4):137. 

Identification of a New Aggressive Axis Driven by Ciliogenesis and Absence of VDAC1-ΔC in Clear Cell Renal Cell Carcinoma Patients Fabbri L, Dufies M, Lacas-Gervais S, Gardie B, Gad-Lapiteau S, Parola J, Nottet N, Meyenberg Cunha de Padua M, Contenti J, Borchiellini D, Ferrero JM, Leclercq NR, Ambrosetti D, Mograbi B, Richard S, Viotti J, Chamorey E, Sadaghianloo N, Rouleau M, Craigen WJ, Mari B, Clavel S, Pagès G, Pouysségur J, Bost F, Mazure NM. Theranostics. 2020 Feb 3;10(6):2696-2713.

Nanotubular structures via templateless electropolymerization using thieno[3,4-b]thiophene monomers with various substituents and polar linkers  S. Sow, A. Dramé, E. Y. Thiam, F. Orange, A.SeneS. Y. Dieng, F. Guittard,T. Darmanin. Progress in Organic Coatings . (January) 2020, 138.

The C-terminal Domain of EFA6A Interacts Directly With F-actin and Assembles F-actin Bundles Macia E, Partisani M, Wang H, Lacas-Gervais S, Le Clainche C, Luton F, Franco M. Sci Rep. 2019 Dec 16;9(1). 

A MIF-like Effector Suppresses Plant Immunity and Facilitates Nematode Parasitism by Interacting With Plant Annexins Zhao J, Li L, Liu Q, Liu P, Li S, Yang D, Chen Y, Pagnotta S, Favery B, Abad P, Jian H. J Exp Bot. 2019 Oct 24;70(20):5943-5958. 

Variations in surface structures and wettability in the genus Pachnoda Burmeister. G. Godeau, F. Orange, R-P Godeau, C. R Szczepanski, F. Guittard, T. Darmanin. Bioinspired, Biomimetic and Nanobiomaterials, 8 (3), Sept. 2019, pp. 181-189.

Uranium Uptake in Paracentrotus lividus Sea Urchin, Accumulation and Speciation. Reeves B, Beccia MR, Solari PL, Smiles DE, Shuh DK, Berthomieu C, Marcellin D, Bremond N, Mangialajo L, Pagnotta S, Monfort M, Moulin C, Den Auwer C. Environ Sci Technol. 2019 Jul 16;53(14):7974-7983. 

Mitochondrial Defect in Muscle Precedes Neuromuscular Junction Degeneration and Motor Neuron Death in CHCHD10 S59L/+ Mouse Genin EC, Madji Hounoum B, Bannwarth S, Fragaki K, Lacas-Gervais S, Mauri-Crouzet A, Lespinasse F, Neveu J, Ropert B, Augé G, Cochaud C, Lefebvre-Omar C, Bigou S, Chiot A, Mochel F, Boillée S, Lobsiger CS, Bohl D, Ricci JE, Paquis-Flucklinger V. Acta Neuropathol. 2019 Jul;138(1):123-145.

Uranium Effect on Osteocytic Cells In Vitro Hurault L, Creff G, Hagège A, Santucci-Darmanin S, Pagnotta S, Farlay D, Den Auwer C, Pierrefite-Carle V, Carle GF. Toxicol Sci. 2019 Jul 1;170(1):199-209.

TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells.  Arhatte M, Gunaratne GS, El Boustany C, Kuo IY, Moro C, Duprat F, Plaisant M, Duval H, Li D, Picard N, Couvreux A, Duranton C, Rubera I, Pagnotta S, Lacas-Gervais S, Ehrlich BE, Marchant JS, Savage AM, van Eeden FJM, Wilkinson RN, Demolombe S, Honoré E, Patel A. Nat Commun. 2019 May 2;10(1):2024.

Modulation of the ATM/autophagy pathway by a G-quadruplex ligand tips the balance between senescence and apoptosis in cancer cells. Beauvarlet J, Bensadoun P, Darbo E, Labrunie G, Rousseau B, Richard E, Draskovic I, Londono-Vallejo A, Dupuy JW, Nath Das R, Guédin A, Robert G, Orange F, Croce S, Valesco V, Soubeyran P, Ryan KM, Mergny JL, Djavaheri-Mergny M. Nucleic Acids Res. 2019 Apr 8;47(6):2739-2756.

Novel budding mode in Polyandrocarpa zorritensis: a model for comparative studies on asexual development and whole body regeneration.
Scelzo M, Alié A, Pagnotta S, Lejeune C, Henry P, Gilletta L, Hiebert LS, Mastrototaro F, Tiozzo S. Evodevo. 2019 Apr 3;10:7.

Micro- and nanoscopic observations of sexual dimorphisms in Mecynorhina polyphemus confluens (Kraatz, 1890) (Coleoptera, Cetoniidae, Goliathini) and consequences for surface wettability.  Montreuil O, Candet C, Bonaccorso A, Szczepanski CR, Orange F, Godeau RP, Guittard F, Darmanin T, Godeau G. Arthropod Struct Dev. 2019 Mar;49:10-18. 

Quality Control of a Functionalized Polymer Catalyst by Energy Dispersive X-ray Spectrometry (EDX or EDS). Hector D, Olivero S, Orange F, Duñach E, Gal JF. Anal Chem. 2019 Feb 5;91(3):1773-1778.

Lysosomal acid ceramidase ASAH1 controls the transition between invasive and proliferative phenotype in melanoma cells. Leclerc J, Garandeau D, Pandiani C, Gaudel C, Bille K, Nottet N, Garcia V, Colosetti P, Pagnotta S, Bahadoran P, Tondeur G, Mograbi B, Dalle S, Caramel J, Levade T, Ballotti R, Andrieu-Abadie N, Bertolotto C. Oncogene. 2019 Feb;38(8):1282-1295 

On-site secretory vesicle delivery drives filamentous growth in the fungal pathogen Candida albicans. Weiner A, Orange F, Lacas-Gervais S, Rechav K, Ghugtyal V, Bassilana M, Arkowitz RA. Cell Microbiol. 2019 Jan;21(1)

Epstein-Barr Virus-Infected Plasma Cells Infiltrate Erosive Oral Lichen Planus. Raybaud H, Olivieri CV, Lupi-Pegurier L, Pagnotta S, Marsault R, Cardot-Leccia N, Doglio A. J Dent Res. 2018 Dec;97(13):1494-1500 

Loss of MICOS complex integrity and mitochondrial damage, but not TDP-43 mitochondrial localisation, are likely associated with severity of CHCHD10-related diseases.  Genin EC, Bannwarth S, Lespinasse F, Ortega-Vila B, Fragaki K, Itoh K, Villa E, Lacas-Gervais S, Jokela M, Auranen M, Ylikallio E, Mauri-Crouzet A, Tyynismaa H, Vihola A, Augé G, Cochaud C, Sesaki H, Ricci JE, Udd B, Vives-Bauza C, Paquis-Flucklinger V. Neurobiol Dis. 2018 Nov;119:159-171.

Towards the development of chitosan nanoparticles for plutonium pulmonary decorporation. Léost L, Roques J, Van Der Meeren A, Vincent L, Sbirrazzuoli N, Hennig C, Rossberg A, Aupiais J, Pagnotta S, Den Auwer C, Di Giorgio C. Dalton Trans. 2018 Aug 21;47(33):11605-11618.

Variation of Goliathus orientalis (Moser, 1909) Elytra Nanostructurations and Their Impact on Wettability Godeau G, Godeau RP, Orange F, Szczepanski CR, Guittard F, Darmanin T (2018), Biomimetics 2018 Jun, 3(2), 6.

A giant amphipathic helix from a perilipin that is adapted for coating lipid droplets. Čopič A, Antoine-Bally S, Giménez-Andrés M, La Torre Garay C, Antonny B, Manni MM, Pagnotta S, Guihot J, Jackson CL. Nat Commun. 2018 Apr 6;9(1):1332.

Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage. Manni MM, Tiberti ML, Pagnotta S, Barelli H, Gautier R, Antonny B. Elife. 2018 Mar 15;7.

Lysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol Production. Viaud M, Ivanov S, Vujic N, Duta-Mare M, Aira LE, Barouillet T, Garcia E, Orange F, Dugail I, Hainault I, Stehlik C, Marchetti S, Boyer L, Guinamard R, Foufelle F, Bochem AE, Hovingh KG, Thorp EB, Gautier EL, Kratky D, Da Silva-Jardine PA, Yvan-Charvet L. Circ Res. 2018 Mar 9.

Bax Inhibitor-1 protects from Non-Alcoholic Steatohepatitis by limiting IRE1α signaling. Lebeaupin C, Vallée D, Rousseau D, Patouraux S, Bonnafous S, Adam G, Luciano F, Luci C, Anty R, Iannelli A, Marchetti S, Kroemer G, Lacas-Gervais S, Tran A, Gual P, Bailly-Maitre B. Hepatology. 2018 Feb 19

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines. Dufies M, Ambrosetti D, Boulakirba S, Calleja A, Savy C, Furstoss N, Zerhouni M, Parola J, Aira-Diaz L, Marchetti S, Orange F, Lacas-Gervais S, Luciano F, Jacquel A, Robert G, Pagès G, Auberger P. Oncotarget. 2018 Feb;9(13):10920-10933.

La trasformazione delle materie coloranti ricche di goethite ed ematite nel sito di Riparo Tagliente (NE Italia) durante l’Epigravettiano recente:  ricostruzione sperimentale della «chaîne-opératoire».  Sardelli S, Fontana F, Regert M, Orange F, Zorzin R, Dubar M, Durrenmath G, Carré A (2018) Annali dell'Università degli Studi di Ferrara, 13, 24-26.

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarizationpotential. S. Boulakirba, A. Pfeifer, R. Mhaidly, S. Obba, M. Goulard, T. Schmitt, P. Chaintreuil, A. Calleja, N. Furstoss, F. Orange, S. Lacas-Gervais, L. Boyer, S. Marchetti, Els Verhoeyen, F. Luciano, G. Robert, P. Auberger, and A. Jacquel, Sci Rep. 2018 Jan 10;8(1):256.

Mitochondrial fission is associated with UCP1 activity in human brite/beige adipocytes. Pisani DF, Barquissau V, Chambard JC, Beuzelin D, Ghandour RA, Giroud M, Mairal A, Pagnotta S, Cinti S, Langin D, Amri EZ. Mol Metab. 2018 Jan;7:35-44.

Sterol transfer, PI4P consumption, and control of membrane lipid order by endogenous OSBP. Mesmin B, Bigay J, Polidori J, Jamecna D, Lacas-Gervais S, Antonny B. EMBO J. 2017 Oct 4.

Expression patterns of sterol transporters NPC1 and NPC2 in the cnidarian-dinoflagellate symbiosis. Dani V, Priouzeau F, Mertz M, Mondin M, Pagnotta S, Lacas-Gervais S, Davy SK, Sabourault C. Cell Microbiol. 2017 Oct;19(10).

New dating evidence of the early presence of hominins in Southern Europe. Michel V, Shen CC, Woodhead J, Hu HM, Wu CC, Moullé PÉ, Khatib S, Cauche D, Moncel MH, Valensi P, Chou YM, Gallet S, Echassoux A, Orange F, de Lumley H. Sci Rep. 2017 Aug 30;7(1):10074.

Essential and selective role of SNX12 in transport of endocytic and retrograde cargo. Priya A, Sugatha J, Parveen S, Lacas-Gervais S, Raj P, Gilleron J, Datta S. J Cell Sci. 2017 Aug 15;130(16):2707-2721.

A travel in the Echeveria genus wettability's world.  G.Godeau, J-P Laugier, F.Orange, R-P Godeau, F.Guittard, T.Darmanin, Applied Surface Science Volume 411, 291–302. (2017 July,31)

Preparation of polypropylene nanocomposites by melt‐mixing: Comparison between three organoclays. G Normand, A Mija, S Pagnotta, E. Peuvrel-Disdier, B. Vergnes. Journal of Applied Polymer Science, 2017 (July 20).

The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells. Loubiere C, Clavel S, Gilleron J, Harisseh R, Fauconnier J, Ben-Sahra I, Kaminski L, Laurent K, Herkenne S, Lacas-Gervais S, Ambrosetti D, Alcor D, Rocchi S, Cormont M, Michiels JF, Mari B, Mazure NM, Scorrano L, Lacampagne A, Gharib A, Tanti JF, Bost F. Sci Rep. 2017 Jul 11;7(1):5040.

A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions. Rouzier C, Moore D, Delorme C, Lacas-Gervais S, Ait-El-Mkadem S, Fragaki K, Burté F, Serre V, Bannwarth S, Chaussenot A, Catala M, Yu-Wai-Man P, Paquis-Flucklinger V. Hum Mol Genet. 2017 May 1;26(9):1786.

Development and evaluation of injectable nanosized drug delivery systems for apigenin. Karim R, Palazzo C, Laloy J, Delvigne AS, Vanslambrouck S, Jerome C, Lepeltier E, Orange F, Dogne JM, Evrard B, Passirani C, Piel G. Int J Pharm. 2017 Apr 27. pii: S0378-5173(17)30374-5.

Recombinant tandem of pore-domains in a Weakly Inward rectifying K+ channel 2 (TWIK2) forms active lysosomal channels. Bobak N, Feliciangeli S, Chen CC, Ben Soussia I, Bittner S, Pagnotta S, Ruck T, Biel M, Wahl-Schott C, Grimm C, Meuth SG, Lesage F. Sci Rep. 2017 Apr 5;7(1):649.

Effect of natural uranium on the UMR-106 osteoblastic cell line: impairment of the autophagic process as an underlying mechanism of uranium toxicity. Pierrefite-Carle V, Santucci-Darmanin S, Breuil V, Gritsaenko T, Vidaud C, Creff G, Solari PL, Pagnotta S, Al-Sahlanee R, Auwer CD, Carle GF. Arch Toxicol. 2017 Apr;91(4):1903-1914.

Cell-based therapy using miR-302-367 expressing cells represses glioblastoma growth. Fareh M, Almairac F, Turchi L, Burel-Vandenbos F, Paquis P, Fontaine D, Lacas-Gervais S, Junier MP, Chneiweiss H, Virolle T. Cell Death Dis. 2017 Mar 30;8(3)

A novel CISD2 mutation associated with a classical Wolfram syndrome phenotype alters Ca2+ homeostasis and ER-mitochondria interactions. Rouzier C, Moore D, Delorme C, Lacas-Gervais S, Ait-El-Mkadem S, Fragaki K, Burté F, Serre V, Bannwarth S, Chaussenot A, Catala M, Yu-Wai-Man P, Paquis-Flucklinger V. Hum Mol Genet. 2017 Mar 6.

In Vitro and in Vivo Evaluation of Fully Substituted (5-(3-Ethoxy-3-oxopropynyl)-4-(ethoxycarbonyl)-1,2,3-triazolyl-glycosides as Original Nucleoside Analogues to Circumvent Resistance in Myeloid Malignancies. Amdouni H, Robert G, Driowya M, Furstoss N, Métier C, Dubois A, Dufies M, Zerhouni M, Orange F, Lacas-Gervais S, Bougrin K, Martin AR, Auberger P, Benhida R. J Med Chem. 2017 Feb 

PEGylated and Functionalized Aliphatic Polycarbonate Polyplex Nanoparticles for Intravenous Administration of HDAC5 siRNA in Cancer Therapy. Frère A, Baroni A, Hendrick E, Delvigne AS, Orange F, Peulen O, Dakwar GR, Diricq J, Dubois P, Evrard B, Remaut K, Braeckmans K, De Smedt SC, Laloy J, Dogné JM, Feller G, Mespouille L, Mottet D, Piel G. ACS Appl Mater Interfaces. 2017 Jan 25;9(3):2181-2195. 

Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis. Ben-Othman N, Vieira A, Courtney M, Record F, Gjernes E, Avolio F, Hadzic B, Druelle N, Napolitano T, Navarro-Sanz S, Silvano S, Al-Hasani K, Pfeifer A, Lacas-Gervais S, Leuckx G, Marroquí L, Thévenet J, Madsen OD, Eizirik DL, Heimberg H, Kerr-Conte J, Pattou F, Mansouri A, Collombat P. Cell. 2017 Jan 12;168(1-2):73-85.

Gallium enhances reconstructive properties of a calcium phosphate bone biomaterial. Strazic Geljic I, Melis N, Boukhechba F, Schaub S, Mellier C, Janvier P, Laugier JP, Bouler JM, Verron E, Scimeca JC. J Tissue Eng Regen Med. 2017 Jan 12.

Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes. Del Prete D, Suski JM, Oulès B, Debayle D, Gay AS, Lacas-Gervais S, Bussiere R, Bauer C, Pinton P, Paterlini-Bréchot P, Wieckowski MR, Checler F, Chami M. J Alzheimers Dis. 2017;55(4):1549-1570.

One-pot Staudinger Ureation reaction to develop superhydrophobic/oleophobic surfaces with urea linkers.G. Godeau , K. Boutet, C. Mortier, J-P Laugier, F. Guittard, T. Darmanin. Materials and Design, Oct 2016.

Bioinspired Rose-Petal-Like Substrates Generated by Electropolymerization on Micropatterned Gold Substrates T. Darmanin, R. Bombera, P. Colpo, A. Valsesia,  J-P Laugier, F. Rossi, F. Guittard. ChemPlusChem, Oct 2016

Thermal and menthol stress induce different cellular events during sea anemone bleaching V. Dani, F. Priouzeau, S. Pagnotta, D. Carette, J-P. Laugier, C. Sabourault, Symbiosis. July 2016, 69, (3) : 175–192.Materials and Design 2016 Oct.

Sex-specific autophagy modulation in osteoblastic lineage: a critical function to counteract bone loss in female. Camuzard O, Santucci-Darmanin S, Breuil V, Cros C, Gritsaenko T, Pagnotta S, Cailleteau L, Battaglia S, Panaïa-Ferrari P, Heymann D, Carle GF, Pierrefite-Carle V. Oncotarget. 2016 Sep 13

Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome. Melis N, Rubera I, Cougnon M, Giraud S, Mograbi B, Belaid A, Pisani DF, Huber SM, Lacas-Gervais S, Fragaki K, Blondeau N, Vigne P, Frelin C, Hauet T, Duranton C, Tauc M. J Am Soc Nephrol. 2016 Sep 9

Effect of natural uranium on the UMR-106 osteoblastic cell line: impairment of the autophagic process as an underlying mechanism of uranium toxicity. Pierrefite-Carle V, Santucci-Darmanin S, Breuil V, Gritsaenko T, Vidaud C, Creff G, Solari PL, Pagnotta S, Al-Sahlanee R, Auwer CD, Carle GF. Arch Toxicol. 2016 Sep 1.

FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria. Doghman-Bouguerra M, Granatiero V, Sbiera S, Sbiera I, Lacas-Gervais S, Brau F, Fassnacht M, Rizzuto R, Lalli E. EMBO Rep. 2016 Sep;17(9):1264-80

Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology. Lauritzen I, Pardossi-Piquard R, Bourgeois A, Pagnotta S, Biferi MG, Barkats M, Lacor P, Klein W, Bauer C, Checler F. Acta Neuropathol. 2016 Aug;132(2):257-76.

Influence of the monomer structure and electrochemical parameters on the formation of nanotubes with parahydrophobic properties (high water adhesion) by a templateless electropolymerization process. T.Darmanin, J-P Laugier, F. Orange, F. Guittard, Journal of Colloid and Interface Science.  2016 March; 466 : 413–424.

Reply: High prevalence of CHCHD10 mutations in patients with frontotemporal dementia from China. Bannwarth S, Ait-El-Mkadem S, Chaussenot A, Genin EC, Lacas-Gervais S, Fragaki K, Berg-Alonso L, Kageyama Y, Serre V, Moore D, Verschueren A, Rouzier C, Le Ber I, Augé G, Cochaud C, Lespinasse F, N'Guyen K, de Septenville A, Brice A, Yu-Wai-Man P, Sesaki H, Pouget J, Paquis-Flucklinger V. Brain. 2016 Apr;139(Pt 4):e22.

Inactivation of Pif1 helicase causes a mitochondrial myopathy in mice. Bannwarth S, Berg-Alonso L, Augé G, Fragaki K, Kolesar JE, Lespinasse F, Lacas-Gervais S, Burel-Vandenbos F, Villa E, Belmonte F, Michiels JF, Ricci JE, Gherardi R, Harrington L, Kaufman BA, Paquis-Flucklinger V.  Mitochondrion.  2016 Feb 24. p: S1567-7249(16)30008-3