(*Correspending)

46. Park W, Wei S, Kim BS, Kim B, Bae SJ, Chae YC, Ryu D, Ha KT (2023) Diversity and complexity of cell death: a historical review. Exp Mol Med.;55(8):1573-1594 [Pubmed]

45. Jang HJ, Lee YH, Dao T, Jo Y, Khim KW, Eom HJ, Lee JE, Song YJ, Choi SS, Park K, Ji H, Chae YC, Myung K, Kim H, Ryu D, Park NH, Park SH, Choi JH. (2023) Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy. Exp Mol Med.;55(8):1720-1733 [Pubmed]

44. Lee YJ, Shin KJ, Chae YC*  (2023) Protocol for evaluation of tumor-derived exosome-induced cancer cell metastasis in a mouse model. STAR Protocols ;4(3):102444 [Pubmed]

43. Kang Y, Han YG, Khim KW, Choi WG, Ju MK, Park K, Shin KJ, Chae YC, Choi JH, Kim H, Lee JY. (2023) Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase. Nucleic Acids Res. ;51(15):7936-7950 [Pubmed]

42. Yu S, Song JH, Kim HS, Hong S, Park SK, Park SH, Lee J, Chae YC, Park JH, Lee YG. (2023) Patulin alleviates hepatic lipid accumulation by regulating lipogenesis and mitochondrial respiration. Life Sci ;326:121816. [Pubmed]

41. Lee YJ, Shin KJ, Jang HJ, Ryu JS, Lee CY, Yoon JH, Seo JK, Park S, Lee S, Je AR, Huh YH, Kong SY, Kwon T, Suh PG*, Chae YC* (2023) GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis. Developmental Cell; 58(4):320-334.e8 [Pubmed]

40. Jun H, Jang E, Kim H, Yeo M, Park SG, Lee J, Shin KJ, Chae YC, Kang S, Kim E. (2022) TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth. J Control Release; 349:367-378 [Pubmed]

39. Min S, Kim JY, Cho HM, Park S, Hwang JM, You H, Chae YC, Lee WJ, Sun W, Kang D, Lee S, Kang SW. (2022) Heat shock protein 60 couples an oxidative stress-responsive p38/MK2 signaling and NF-κB survival machinery in cancer cells. Redox Biol; 51:102293. [Pubmed]

38. Lee YG, Park DH, Chae YC* (2022) Role of Mitochondrial Stress Response in Cancer Progression. Cells; 11(5):771 [Pubmed]

37. Lee YH, Jang HJ, Kim S, Choi SS, Khim KW, Eom HJ, Hyun J, Shin KJ, Chae YC, Kim H, Park J, Park NH, Woo CY, Hong CH, Koh EH, Nam D, Choi JH. (2022) Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA. Elife; 10:e70472. [PubMed]

36. Shin KJ, Jang HJ, Lee YJ, Lee YG, Suh PG, Yang YR*, Chae YC* (2021) Phospholipase Cγ1 represses colorectal cancer growth by inhibiting the Wnt/β-catenin signaling axis. Biochem Biophys Res Commun.; 577:103-109. [PubMed]

35. Ju MK, Shin KJ, Lee JR, Khim KW, Lee EA, Ra JS, Kim BG, Jo H, Yoon JH, Kim TM, Myung K, Choi JH*, Kim H*, Chae YC* (2021) NSMF promotes the replication stress-induced DNA damage response for genome maintenance. Nucleic Acids Research; 49(10):5605-5622 [PubMed]

34. Lee YG, Kim HW, Nam Y, Shin KJ, Lee YJ, Park DH, Rhee HW, Seo JK, Chae YC* (2021) LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival. Oncogenesis; 10(2):18 [PubMed]

33. Bae Y, Lee SK, Chae YC, Park CY, Kang S (2021) Accessibility-dependent topology studies of membrane proteins using a SpyTag/SpyCatcher protein-ligation system. Int J Biol Macromol.; 175:171-178 [PubMed]

32. Park SG, Choi B, Bae Y, Lee YG, Park SA, Chae YC*, Kang S* (2020) Selective and Effective Cancer Treatments using Target‐Switchable Intracellular Bacterial Toxin Delivery Systems. ADVANCED THERAPEUTICS; 3(9): 2000043 [PubMed]

31. Jang DK, Lee YG, Chae YC, Lee JK, Paik WH, Lee SH, Kim YT, Ryu JK (2020) GDC-0980 (apitolisib) treatment with gemcitabine and/or cisplatin synergistically reduces cholangiocarcinoma cell growth by suppressing the PI3K/Akt/mTOR pathway. Biochem Biophys Res Commun; 529(4):1242-1248. [PubMed]

30. Choi SS, Lee SK, Kim JK, Park HK, Lee E, Jang J, Lee YH, Khim KW, Hyun JM, Eom HJ, Lee S, Kang BH, Chae YC, Myung K, Myung SJ, Park CY, Choi JH (2020) Flightless-1 inhibits ER stress-induced apoptosis in colorectal cancer cells by regulating Ca 2+ homeostasis. Exp Mol Med. 52(6):940-950. [PubMed]

29. Park HK, Yoon NG, Lee JE, Hu S, Yoon S, Kim SY, Hong JH, Nam D, Chae YC, Park JB, Kang BH (2020) Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1. Exp Mol Med.; 52(1):79-91 [PubMed]

28. Jang HJ, Lim S, Kim JM, Yoon S, Lee CY, Hwang HJ, Shin JW, Shin KJ, Kim HY, Park KI, Nam D, Lee JY, Yea K, Hirabayashi Y, Lee YJ, Chae YC, Suh PG, Choi JH (2020) Glucosylceramide synthase regulates adipo-osteogenic differentiation through synergistic activation of PPARγ with GlcCer. FASEB J. 34(1):1270-1287 [PubMed]

27. Lee YG, Nam Y, Shin KJ, Yoon S, Park WS, Joung JY, Seo JK, Jang J, Lee S, Nam D, Caino MC, Suh PG, Chae YC* (2020) Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer. Cancer Letters; 471:72-87. [PubMed]

26. Seo JH, Chae YC*, Kossenkov AV, Lee YG, Tang HY, Agarwal E, Gabrilovich DI, Languino LR, Speicher DW, Shastrula PK, Storaci AM, Ferrero S, Gaudioso G, Caroli M, Tosi D, Giroda M, Vaira V, Rebecca VW, Herlyn M, Xiao M, Fingerman D, Martorella A, Skordalakes E, Altieri DC* (2019) MFF regulation of mitochondrial cell death is a therapeutic target in cancer. Cancer Research; doi: 10.1158/0008-5472.CAN-19-1982. [PubMed]

25. Seo JH, Agarwal E, Chae YC*, Lee YG, Garlick DS, Storaci AM, Ferrero S, Gaudioso G, Gianelli U, Vaira V, Altieri DC* (2019) Mitochondrial fission factor is a novel Myc-dependent regulator of mitochondrial permeability in cancer. EBioMedicine. pii: S2352-3964(19)30615-2. [PubMed]

24. Sung JS, Kang CW, Kang S, Jang Y, Chae YC, Kim BG, Cho NH (2019) ITGB4-mediated metabolic reprogramming of cancer-associated fibroblasts. Oncogene. doi: 10.1038/s41388-019-1014-0. [PubMed]

23. Hwang HJ, Yang YR, Kim HY, Choi Y, Park KS, Lee H, Ma JS, Yamamoto M, Kim J, Chae YC, Choi JH, Cocco L, Berggren PO, Jang HJ, Suh PG (2019) Phospholipase C-β1 potentiates glucose-stimulated insulin secretion. FASEB J.;33(10):10668-10679. doi: 10.1096/fj.201802732RR. [PubMed]

22. Park HK, Hong JH, Oh YT, Kim SS, Yin J, Lee AJ, Chae YC, Kim JH, Park SH, Park CK, Park MJ, Park JB, Kang BH (2019) Interplay between TRAP1 and Sirtuin-3 Modulates Mitochondrial Respiration and Oxidative Stress to Maintain Stemness of Glioma Stem Cells. Cancer Research;79(7):1369-1382 [PubMed]

21. Chae YC, Kim JH (2018) Cancer stem cell metabolism: target for cancer therapy. BMB Report; 51(7):319-326. [PubMed]

20. Boucherat O, Peterlini T, Bourgeois A, Nadeau V, Breuils-Bonnet S, Boilet-Molez S, Potus F, Meloche J, Chabot S, Lambert C, Tremblay E, Chae YC, Altieri DC, Sutendra G, Michelakis ED, Paulin R, Provencher S, Bonnet S (2018) Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension. Am J Respir Crit Care Med. doi: 10.1164/rccm.201708-1751OC. [PubMed]

19. Jang HJ, Suh PG, Lee YJ, Shin KJ, Cocco L, Chae YC* (2018) PLCγ1: Potential arbitrator of cancer progression. Adv Biol Regul.;67:179-189. doi:10.1016/j.jbior.2017.11.003. [PubMed]

(Before 2017~)

18. Chae YC, Vaira V, Caino MC, Tang HY, Seo JH, Kossenkov AV, Ottobrini L, Martelli C, Lucignani G, Bertolini I, Locatelli M, Bryant KG, Ghosh JC, Lisanti S, Ku B, Bosari S, Languino LR, Speicher DW, and Altieri DC (2016) Mitochondrial Akt Regulation of Hypoxic Metabolic Reprogramming. Cancer Cell; 30(2):257-272. [PubMed]

17. Seo JH, Rivadeneira DB, Caino MC, Chae YC, Speicher DW, Tang HY, Vaira V, Bosari S, Palleschi A, Rampini P, Kossenkov AV, Languino LR, and Altieri DC (2016) The mitochondrial unfoldase-peptidase complex clpxp controls bioenergetics stress and metastasis. PLOS Biology;14(7):e1002507. [PubMed]

16. Zhang G, Frederick DT, Wu L, Wei Z, Krepler C, Srinivasan S, Chae YC, Xu X, Choi H, Dimwamwa E, Ope O, Shannan B, Basu D, Zhang D, Guha M, Xiao M, Randell S, Sproesser K, Xu W, Liu J, Karakousis GC, Schuchter LM, Gangadhar TC, Amaravadi RK, Gu M, Xu C, Ghosh A, Xu W, Tian T, Zhang J, Zha S, Liu Q, Brafford P, Weeraratna A, Davies MA, Wargo JA, Avadhani NG, Lu Y, Mills GB, Altieri DC, Flaherty KT, Herlyn M (2016) Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors. Journal of Clinical Investigation pii: 82661. doi: 10.1172/JCI82661 [PubMed]

15. Kim KL, Kim D, Lee S, Kim SJ, Noh JE, Kim JH, Chae YC, Lee JB, Ryu SH (2016) Pairwise detection of site-specific receptor phosphorylations using single-molecule blotting. Nature Communication; 7:11107. doi: 10.1038/ncomms11107 [PubMed]

14. Caino MC, Ghosh JC, Chae YC, Vaira V, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, Webster MR, Weeraratna A, Bosari S, Languino L, Altieri DC (2015) PI3K Therapy Reprograms Mitochondrial Trafficking to Fuel Tumor Cell Invasion. Proc Natl Acad Sci USA ;112(28):8638-43 [PubMed]

13. Ghosh JC , Siegelin MD, Vaira V, Faversani A, Tavecchio M, Chae YC, Lisanti S, Rampini P, Giroda M, Caino MC, Seo JH, Kossenkov AV, Michalek RD, Schultz DC, Bosari S, Languino L, Altieri DC (2015) Adaptive Mitochondrial Reprogramming and Resistance to PI3K Therapy. J Natl Cancer Inst.;107(3). [PubMed] 

12. Lisanti S, Tavecchio M, Chae YC, Liu Q, Brice AK, Thakur ML, Languino LR, and Altieri DC (2014) Deletion of the Mitochondrial Chaperone TRAP-1 Uncovers Global Reprogramming of Metabolic Networks. Cell Reports; 8(3):671-7 [PubMed] 

11. Chae YC, Angelin A, Lisanti S, Kossenkov AA, Speicher KD, Wang H, Powers JF, Tischler AS, Pacak K, Fliedner S, Michalek RD, Karoly ED, Wallace DC, Languino LR, Speicher DW and Altieri DC (2013) Landscape of the Mitochondrial HSP90 Metabolome in Tumors. Nature Communications; 4, Article number: 2139 [PubMed] 

10. Caino MC, Chae YC, Vaira V, Ferrero S, Nosotti M, Martin NM, Weeraratna A, O’Connell M, Jernigan D, Fatatis A, Languino LR, Bosari S and Altieri DC (2013) Metabolic Stress Control of Cytoskeletal Dynamics and Metastasis. Journal of Clinical Investigation; 123(7):2907–2920 [PubMed] 

9. Chae YC, Caino MC, Lisanti S, Ghosh JC, Dohi T, Danial NN, Villanueva J, Ferrero S, Vaira V, Santambrogio L, Bosari S, Languino LR, Herlyn M, Altieri DC (2012) Control of Tumor Bioenergetics and Survival Stress Signaling by Mitochondrial HSP90s. Cancer Cell; 22(3):331-44. [PubMed] 

8. Chae YC, Kim KL, Ha SH, Kim J, Suh PG and Ryu SH (2010) PKCd-mediated phosphorylation of phospholipase D controls integrin mediated cell spreading. Mol Cell Biol.;  30(21):5086-98. [PubMed] 

7. Chae YC, Lee SM, Heo K, Lee HY, Ha SH, JungYW, Kim JH, Ihara Y, Suh PG and Ryu SH (2009) Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity. Cellular Signalling;21(12):1818-26 [PubMed] 

6. Lee S, Ha IS, Kim JH, Park KS, Han KH, Kim SH, Chae YC, Kim SH, Kim YH, Suh PG, Ryu SH, Kim JE, Bang K, Hwang JI, Yang J, Park KW, Chung J, Ahn C (2008) Hydrogen peroxide-induced VCAM-1 expression in pancreatic islets and beta-cells through extracellular Ca2+ influx. Transplantation; 86(9):1257-66. [PubMed] 

5. Lee HY, Yea K, Kim J, Lee BD, Chae YC, Kim HS, Lee DW, Kim SH, Cho JH, Jin CJ, Koh DS, Park KS, Suh PG, Ryu SH (2008) Epidermal Growth Factor Increases Insulin Secretion and Lowers Blood Glucose in Diabetic Mice. J Cell Mol Med;12(5A):1593-1604. [PubMed] 

4. Chae YC, Kim KL, Kim HW, Lee HY, Heo WD, Meyer T, Suh PG, Ryu SH (2008) Phospholipase D Activity Regulates Integrin-mediated Cell Spreading and Migration by Inducing GTP-Rac Translocation to the Plasma Membrane. Mol Biol Cell ;19(7):3111-23. [PubMed] 

3. Heo K, Ha SH, Chae YC, Lee S, Oh YS, Kim YH, Kim SH, Kim JH, Mizoguchi A, Itoh TJ, Kwon HM, Ryu SH, Suh PG (2006) RGS2 promotes formation of neurites by stimulating microtubule polymerization. Cellular Signalling;18(12):2182-2192. [PubMed] 

2. Chae YC, Lee S, Lee HY, Heo K, Kim JH, Kim JH, Suh PG, Ryu SH (2005) Inhibition of Muscarinic Receptor-linked Phospholipase D Activation by Association with Tubulin. Journal of Biological Chemistry; 280(5), 3723-3730 [PubMed] 

1. Lee HY, Park JB, Jang IH, Chae YC, Kim JH, Kim IS, Suh PG, Ryu SH (2004) Munc-18-1 inhibits phospholipase D activity by direct interaction in an epidermal growth factor-reversible manner. Journal of Biological Chemistry; 279(16): 16339-16348 [PubMed]