UNINA

Gerardino D’Errico is a Full Professor of Physical Chemistry at the Department of Chemical Sciences, University of Naples “Federico II,” where he teaches Physical Chemistry I, Industrial Physical Chemistry, and Applied Physicochemical Methodologies. He has served as a visiting researcher at the Department of Physical Chemistry 1, Lund University (Sweden), and the Max Planck Institute for Biophysical Chemistry in Göttingen (Germany). He is a member of the Editorial Board of the Journal of Surface Engineered Materials and Advanced Technology and acts as a peer reviewer for several international scientific journals.

Gerardino D’Errico is the author of approximately 160 scientific publications and, between 2009 and 2015, was invited to write the annual review on “NMR in Liquid Crystals and Micellar Solutions” for the Nuclear Magnetic Resonance series published by the Royal Society of Chemistry. More recently, he authored two patents: the first pertains to the design and development of selective ruthenium-containing nanocarriers as theranostic antitumor agents, while the second involves the development of a novel method based on electron paramagnetic resonance (EPR) spectroscopy for the early diagnosis of melanoma.

D’Errico’s scientific interests focus on the spectroscopic characterization of the self-aggregation process of amphiphilic molecules in aqueous solution. Initially, his research targeted anionic, cationic, and nonionic surfactants and their mixtures. Subsequently, his studies extended to surfactant-polymer mixtures, both in solution and in gel phases.

Over the past decade, D’Errico’s research has concentrated on supramolecular aggregates formed by natural lipids and their interactions with peptides and proteins. In this context, he is currently investigating biologically relevant processes involving biomembranes, such as viral fusion and the fibrillation of β-amyloid peptides. More recently, he has explored the characterization of stable radicals/paramagnetic centers in pigments (e.g., melanins, polyphenols) and hybrid metal oxides.

To achieve a detailed understanding of the structure and behavior of the systems under investigation, D’Errico has employed a multidisciplinary approach combining various experimental techniques, including UV-visible and circular dichroism (CD) spectroscopies and spectrofluorimetry. Notably, during his research stays in Lund (Sweden) and Göttingen (Germany), he gained extensive expertise in magnetic resonance spectroscopies, such as PGSE and DOSY NMR techniques, as well as spin-probe EPR.

Gerardino D’Errico serves as a consultant for various companies operating in the field of formulation chemistry, including Procter & Gamble, Cleansud, Cleprin, Eurosocap, and Zapi.

Luigi Petraccone is an Associate Professor of Physical Chemistry at the Department of Chemical Sciences, University of Naples Federico II. His research primarily delves into the biophysical chemistry of nucleic acids and biomembranes, with a particular emphasis on the stability and conformational transitions of DNA triple and quadruple helices. Over the years, he has dedicated his efforts to understanding the influence of solution conditions, base composition, and chemical modifications on the formation and stability of these complex DNA structures. His work combines calorimetric, spectroscopic, and computational methods to explore the energetic and structural properties of these multi-stranded configurations, with the ultimate goal of developing modified oligonucleotides possessing novel biophysical properties that hold promise for therapeutic applications. In recognition of his significant contributions to the field of thermal analysis of DNA structures, he was awarded the prestigious "Lucci" Award by the Italian Association of Calorimetry and Thermal Analysis (A.I.C.A.T.) in 2004.

More recently, Prof. Petraccone has expanded his research focus to include the dynamic and thermotropic properties of model biomembranes. His investigations delve into the interactions of these membranes with biological macromolecules and pharmacologically relevant peptides, shedding light on their functional behavior and potential biomedical applications. This shift in focus reflects his commitment to addressing complex biological questions through the lens of physical chemistry.

Prof. Petraccone graduated in Chemistry from the University of Naples Federico II in 1998 and completed his Ph.D. in Chemistry at the same institution in 2002. His academic journey began as a Ph.D. student in the Faculty of Science, where he laid the groundwork for his career in physical chemistry. Following his doctoral studies, he taught chemistry at the University of Sannio, enriching his academic experience. He then undertook a postdoctoral research position at the Faculty of Pharmacy, University of Salerno, where he further honed his expertise in the field. Returning to his alma mater, he served as an Assistant Professor from 2006 to 2015, a period marked by prolific research activity and academic contributions. Since 2015, he has held the position of Associate Professor of Physical Chemistry, continuing to push the boundaries of research and education at the Department of Chemical Sciences.

Matilde Tancredi is a researcher at the University of Naples Federico II, focusing on a project aimed at understanding the self-aggregation mechanisms of biosurfactants to develop nanostructured eco-sustainable formulations. Her work delves into the connections between the microscopic structure and macroscopic behavior of these systems, with the ultimate goal of promoting biosurfactants as an environmentally friendly alternative to conventional surfactants. Her research employs advanced techniques such as polarizing optical microscopy, small-angle neutron and X-ray scattering, electron paramagnetic resonance, and rheological investigations to achieve comprehensive chemical, physical, and functional characterization of the formulations.

During her time at Biopox S.r.l., Matilde explored cutting-edge research on recombinant proteins, focusing on their expression, purification, and industrial applications, including the production of natural and recombinant laccases. This experience provided her with in-depth insights into the biotechnological applications of proteins and their potential for sustainable solutions.

As a teaching assistant in the Department of Agriculture, Matilde supported students in organic chemistry, offering personalized guidance and fostering effective learning strategies. Her dedication to education not only helped students overcome academic challenges but also enriched her own experience as a mentor and educator.

Her experimental thesis in physical chemistry investigated the supramolecular structures of concentrated rhamnolipid solutions, a class of biosurfactants recognized for their ecological and biodegradable properties. By employing advanced electron paramagnetic resonance techniques, Matilde obtained valuable insights into the molecular dynamics and chemical environment of these surfactants, paving the way for their application as eco-friendly alternatives to synthetic surfactants.

Matilde holds a Master’s degree in Chemical Sciences from the University of Naples Federico II, where she focused on the design and characterization of nanostructured formulations based on rhamnolipids. Her academic journey was enriched by advanced training, laboratory experience, and interdisciplinary projects, enabling her to develop expertise in EPR spectroscopy, solution analysis, and scientific data management.

Beyond academic research, Matilde possesses advanced digital skills, a strong aptitude for teamwork, and exceptional analytical abilities. Her well-rounded training and passion for innovation position her as a key contributor to the field of chemical research and eco-sustainable applications.