If you have problems with your PC locking or going to sleep, caffeine will keep it awake. It works by simulating a keypress once every 59 seconds, so your machine thinks you're still working at the keyboard, so won't lock the screen or activate the screensaver.

I just installed this. When I type "caff en" it says "caffeine is already active". But it isn't. Status reports that it's currently active for an indefinite period. Basically it mistakenly thinks caffeine is active. I'm on 10.8, on a retina mbp. I'd love it if this workflow was working.


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Utility of caffeine analysis for the purpose of forensic hair discrimination was evaluated. Methanol extracts of each 5-cm strand of scalp hair, after its incubation at 37 degrees C for 15 h, was analyzed by gas chromatography-mass spectrometry (GC-MS). For quantitative analysis of caffeine, caffeine-d3 was added as internal standard to the methanol extract. Hair specimens were obtained from three victims and from twenty-two volunteers. The results showed that caffeine levels in hair varied according to each individual; caffeine was detected up to a maximum level of 4.19 ng/5-cm hair. The concentrations of caffeine in hair obtained from four different regions of the scalp in twenty-two volunteers showed a coefficient of variation not greater than 24.7% for each individual. Based on our data, it was concluded that caffeine levels give relatively high reliability for discriminating a victim's hair from others at a criminal or accidental scene, although it should be used in combination with morphological examination and ABO blood group determination.

Yes! I found Bartender not too long ago. A few years ago, I had searched for a utility that would do the same thing, but none existed. I might have jumped up and down when I finally found Bartender a few months ago...

I've been tinkering around with interpreters to process time-based arguments with more granularity, and I've been playing with ways to run scripts to configure workflows themselves. When I get both of those tools abstracted well enough, I'll update both the caffeine and caffeinate workflows to employ them. After that, the workflows should allow you to configure the default behavior as you'd like it to.

Depending on the individual, blood concentrations peak anywhere from 15 minutes to two hours after consumption. The metabolism of caffeine also varies person to person, taking two to 12 hours to decrease by half. When blood concentrations peak, you are likely to feel the characteristic effect of caffeine: a boost in energy.

The reason for this phenomenon is that caffeine blocks specific receptors in the brain that mediate critical functions like sleep, arousal, cognition, memory, and learning. When these receptors are operating as usual, it slows brain activity, causing sleepiness or drowsiness.

Background:  One-third of the US population experiences sleep loss, with the potential to impair physical and cognitive performance, reduce productivity, and imperil safety during work and daily activities. Computer-based fatigue-management systems with the ability to predict the effects of sleep schedules on alertness and identify safe and effective caffeine interventions that maximize its stimulating benefits could help mitigate cognitive impairment due to limited sleep. To provide these capabilities to broad communities, we previously released 2B-Alert Web, a publicly available tool for predicting the average alertness level of a group of individuals as a function of time of day, sleep history, and caffeine consumption.

Objective:  In this study, we aim to enhance the capability of the 2B-Alert Web tool by providing the means for it to automatically recommend safe and effective caffeine interventions (time and dose) that lead to optimal alertness levels at user-specified times under any sleep-loss condition.

Methods:  We incorporated a recently developed caffeine-optimization algorithm into the predictive models of the original 2B-Alert Web tool, allowing the system to search for and identify viable caffeine interventions that result in user-specified alertness levels at desired times of the day. To assess the potential benefits of this new capability, we simulated four sleep-deprivation conditions (sustained operations, restricted sleep with morning or evening shift, and night shift with daytime sleep) and compared the alertness levels resulting from the algorithm's recommendations with those based on the US Army caffeine-countermeasure guidelines. In addition, we enhanced the usability of the tool by adopting a drag-and-drop graphical interface for the creation of sleep and caffeine schedules.

Results:  For the 4 simulated conditions, the 2B-Alert Web-proposed interventions increased mean alertness by 36% to 94% and decreased peak alertness impairment by 31% to 71% while using equivalent or smaller doses of caffeine as the corresponding US Army guidelines.

Conclusions:  The enhanced capability of this evidence-based, publicly available tool increases the efficiency by which diverse communities of users can identify safe and effective caffeine interventions to mitigate the effects of sleep loss in the design of research studies and work and rest schedules.

Once configuration of the campaign infrastructure is complete, the attacker has the option of using a Caffeine-provided email management utility (which is offered in both Python or PHP) to craft and send their phishing emails to potential victims.

While an extensive, comprehensive analysis of every utility and component within the Caffeine platform is well beyond the scope of this blog post, several key components of its operation can be used to generate a solid set of high efficacy threat detections when used in concert with one another.

They're everywhere: beverages that promise to keep you energized, revved, and alert. But labels don't have to reveal how much caffeine the products pack. We will. We measured the amount in 27 top-selling energy drinks and shots (see table below).

Safe limits of caffeine consumption are still being studied, but data suggest that most healthy adults can safely consume up to 400 milligrams per day; pregnant women, up to 200 milligrams; and children, up to 45 to 85 milligrams depending on weight. An occasional energy drink is probably fine for most adults. Check the Ratings for caffeine levels and price. And note that some products cost less than half as much as others per serving.

This is an AppleScript I wrote that works in conjunction with a free little utility called Caffeine (you can download it from the developer at , and it is also available on the Mac App Store). Caffeine is a Menubar app that effectively keeps your screensaver and power-saving functions from activating, thereby keeping your screen, and your Mac, awake. I have Caffeine set to load on boot up for ease of use, but you don't have to if that's not your preference, though you will need to have Caffeine running in order for this particular script to work as I've written it.

This is because caffeine blocks the receptors of a neurotransmitter called adenosine, and this increases levels of other neurotransmitters in your brain that regulate your energy levels, including dopamine (2, 3).

Additionally, a large review reported that moderate caffeine consumption could slightly improve power output and time-trial completion time. However, results varied, so the researchers also noted that caffeine may affect people differently (33).

Despite the abundance of studies investigating the behavioural effects of the two substances individually, there is surprisingly little research evaluating the mood and cognitive effects of caffeine and glucose both separately and together. This has been given further impetus from the fact that they are increasingly consumed concomitantly in so-called energy drinks.

These positive effects seen here may be due to the additive/synergistic effects of glucose and caffeine in combination, supporting previous behavioural studies showing that the effects of caffeine and glucose together were significantly better than those of either substance alone (Scholey and Kennedy, 2004). Alternatively, at present, we cannot rule out the possibility that they may be attributable to caffeine contained within this treatment only. Future studies should compare the effects of caffeine alone with the other treatments used in the current study.

Originally developed by Tomas Franzn of Lighthead Software in 2006, Caffeine is a well known and loved utility for many Mac users, and its simplicity has allowed it to continue working perfectly long after active development ceased.

The caffeine levels in Seattle's Puget Sound are so high that researchers recently had to scrap its efforts to use the substance as a marker to track the flow of wastewater, according to a report from the Seattle Post-Intelligencer.

In a study published in the journal Psychiatry Research, Jill M. Williams, director of the division of addiction psychiatry at Rutgers Robert Wood Johnson Medical School, found not only do adult smokers with bipolar disorder and schizophrenia drink the most caffeine, they are at the highest risk of negative health consequences.

At the beginning of the study, participants completed surveys on smoking history, caffeine use, physical health and psychological symptoms. The researchers also collected blood samples to measure serum caffeine levels.

Williams said there are several theories to explain the relationship between caffeine intake and mental illness. One is a well-established association between caffeine and smoking: People with mental illnesses smoke at rates two to three times higher than the general population, and because the tars in cigarette smoke increase the metabolism of caffeine, it takes more caffeine to achieve stimulating effects.

Another theory links high caffeine intake to adenosine receptors and supports a possible self-medication effect among people with mental illness, said Williams. People with mental illnesses also seem to have vulnerabilities to all types of addictive substances, putting them at higher risk for excess intake and more negative consequences. Additionally, the researchers found evidence that mood is linked to caffeine intake, especially bad mood. ff782bc1db

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