Constipation Caused by Tramadol and Other Opioid Pain Medications

Key Takeaways

• Constipation is one of the most common side effects of Tramadol and other opioid medications.

• Most opioid pain relievers can slow down bowel movements.

• Opioid-related constipation usually does not improve on its own.

• Symptoms may continue for as long as you take the medication.

• Lifestyle changes and over-the-counter remedies are often the first steps in treatment.

Why Does Tramadol Cause Constipation?

Buy Ultram Tramadol online helps relieve pain by acting on opioid receptors in the brain. These same receptors are also found in the digestive tract. When Tramadol affects the intestines, bowel movements become slower, making stools harder and more difficult to pass.

As a result, many people experience constipation while taking Tramadol. 

How Long Does Tramadol Constipation Last?

Constipation caused by Tramadol may continue throughout treatment. Unlike some side effects that improve over time, bowel problems often remain until the medication is stopped or treated.

Even after stopping Tramadol, it may take several days for normal bowel function to return. 

Does Tramadol Cause Less Constipation Than Other Opioids?

Compared with stronger opioids such as oxycodone and hydrocodone, tramadol may cause less constipation in some people. This is because it has a weaker effect on opioid receptors in the digestive system.

However, constipation is still a common side effect and should not be ignored. 

Which Opioids Are Less Likely to Cause Constipation?

All opioid medications can lead to constipation, but some may have a lower risk. Research suggests that medications such as:

• Tapentadol (Nucynta)
  
  

• Fentanyl patches
  
  

may cause fewer bowel-related side effects in certain patients. Since fentanyl is delivered through the skin, it may affect the digestive system differently. However, more research is needed to confirm these findings. 

Ways to Relieve Constipation from Tramadol

​There are several options available to help manage opioid-induced constipation. Your healthcare provider can recommend the most suitable treatment based on your symptoms and medical history. 

Simple lifestyle changes can often help, including:

• Drinking plenty of water.

• Eating fiber-rich foods such as fruits, vegetables, and whole grains.

• Staying physically active whenever possible.

Over-the-Counter Laxatives Laxatives are commonly used as a first treatment for opioid-related constipation. A combination of a stool softener and a stimulant laxative may provide better results.

Examples include:

• Docusate (stool softener)

• Senna (stimulant laxative)

People who experienced constipation before starting opioid therapy may benefit the most from these medications

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Prescription Treatments for Opioid-Induced Constipation Several prescription medications are specifically designed to treat opioid-related constipation without affecting pain relief.

These include:

• Methylnaltrexone (Relistor)

• Lubiprostone (Amitiza)

• Naldemedine (Symproic)

• Naloxegol (Movantik)

These medicines work by blocking the effects of opioids in the digestive tract while allowing them to continue relieving pain.

Frequently Asked Questions 

Can Tramadol and Prednisone Be Taken Together?

Yes. In some cases, doctors may prescribe tramadol and prednisone together. Prednisone is a corticosteroid used to reduce inflammation and treat conditions involving an overactive immune system.

Can you take extra-strength Tylenol with Tramadol? 

In many cases, yes. Doctors sometimes recommend combining acetaminophen (Tylenol) with tramadol for better pain control.

However, if your Tramadol product already contains acetaminophen, such as Ultracet, you should monitor your total daily intake carefully. Taking too much acetaminophen can cause serious liver damage.

Can Gabapentin Be Taken After Tramadol?

Gabapentin is sometimes prescribed alongside Tramadol for pain management. However, both medications can increase the risk of excessive drowsiness and slowed breathing.

Always take these medications exactly as directed by your healthcare provider and seek emergency medical attention if you experience breathing problems or severe dizziness.

The Bottom Line 

Constipation is a common side effect of Tramadol and other opioid medications. Fortunately, there are several ways to manage this problem.

Drinking more water, increasing dietary fiber, staying active, and using over-the-counter or prescription treatments can help improve bowel movements.

If constipation becomes severe or persistent, speak with your healthcare provider. Early treatment can help prevent discomfort and improve your quality of life while using opioid pain medications.

Why You Can Trust Our Medical Content

Buy Ultram Trmadol 100mg Online Our content is created and reviewed by experienced healthcare professionals to ensure that the information provided is accurate, reliable, and easy to understand.

Written By Karla Robinson, MD

Dr. Karla Robinson is a board-certified family physician and medical editor with nearly two decades of experience in clinical practice, healthcare administration, and medical education. Her extensive background helps ensure that health information is both accurate and patient-friendly.

Edited By Alex Eastman, PhD, RN

Alex Eastman is a registered nurse and medical editor with expertise in clinical research and healthcare communication. He specializes in reviewing medical updates and improving the clarity and quality of health-related content.

Medically Reviewed ByFarzon A. Nahvi, MD

Dr. Farzon A. Nahvi is an emergency medicine physician, educator, and author. In addition to practicing medicine, he teaches future healthcare professionals and contributes to medical education. His review helps ensure that the information is medically accurate and based on current standards of care.

Our Commitment Every article is carefully written, edited, and medically reviewed to provide trustworthy information that supports informed healthcare decisions. However, this content is intended for educational purposes only and should not replace advice from a qualified healthcare professional. 

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