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CJC-1295 is a tetrasubstituted peptide hormone that consists of 30 amino acids. In the human body, it functions as an analogue of somatoliberin (a natural stimulant of GH secretion).
One of the advantages of CJC-1295 DAC over the widely used analogue GRF 1-29 (synonyms: CJC 1295 w / o, without or without DAC) is a long half-life (up to 2 weeks). CJC 1295 DAC binds to plasma proteins (albumins), which leads to a significant increase in the duration, due to the addition of lysine associated with the non-peptide molecule DAC (Drug Affinity Complex).
"Caution" Be sure to check at the time of purchase CJC-1295 DAC (Drug Affinity Complex) is included, as will the effectiveness and scheme of the course. If there is no Drug in the structure, then you acquire a tetrasubstituted or modified GRF 1-29, which sellers often call CJC 1295, this peptide acts for about 30 minutes.
Storage conditions: 2-8 C degrees (refrigerator). Dosing: Injections subcutaneously or intramuscularly.
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Buy CJC-1295 DAC was invented by the Canadian biotechnology company ConjuChem in 2005, but gained popularity in bodybuilding only by 2010-2011, when the production technology was mastered by third-party companies, including Chinese manufacturers. The duration of action (half-life) is 6-8 days. [1]
ConjuChem initiated a study on CJC-1295 DAC in 2005 to examine the effect of a substance on visceral fat in patients with AIDS and obesity. It is known that in similar situations, growth hormone was used to burn fat in similar situations. [2] The results were very successful for most patients, but the studies were suspended after lawsuits were filed by three patients who suffered a myocardial infarction after a course of CJC-1295 DAC. [3]
CJC-1295 acts on the nuclei of the anterior pituitary gland and stimulates the secretion of growth hormone, mainly through the cAMP of the dependent pathway. [4] The substance binds to GHRH receptors, which belong to the group of G-protein conjugated receptors.
Studies have shown that CJC 1295 DAC has similar effects on growth hormone:
increase in strength
muscle growth
fat burning
improving skin quality (smoothing wrinkles)
increase in bone density
strengthening of ligaments and joints
positive effect on sleep
During the course, there are characteristic sensations of swelling of muscles.
The release of GH by the pituitary gland depends on three main types of regulatory hormones:
Somatostatin, which suppresses GH secretion, provides a pulse-like secretion curve (creates concentration peaks at certain hours, particularly at night).
Growth hormone-releasing hormone (GHRH) is a stimulating release peptide. Administration to the body causes a wavy rise in concentration, which will be weak during the hours when the natural secretion of GH is reduced due to somatostatin, and high during the natural rise in the concentration of GH (for example, at night). In other words, GHRH enhances GH secretion without disrupting the natural pulse curve. Artificial analogues: buy GRF (1-29), aka buy Sermorelin and CJC-1295 for Sale.
Ghrelin (GHRP) - is a modulator of secretion, i.e. regulates the balance between peaks and falls in the concentration of GH. Artificial analogues are buy GHRP-6, buy GHRP-2, buy Hexarelin and buy Ipamorelin. Create a peak concentration of GH immediately after administration, regardless of the time of day and the presence of somatostatin in the blood. With age, ghrelin allows you to maintain the secretion of growth hormone, despite the increasing influence of somatostatin.
Find more information here: https://researchpeptides.net/product/peptides/cjc-1295-dac-2mg/
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