This is a self-directed learning resource designed to be worked through in the clinical environment.
Recognise key symptoms and signs of Parkinson’s disease
Differentiate between idiopathic Parkinson’s disease and other causes of parkinsonism
Understand the basic principles of initial investigations in diagnosing Parkinson’s disease
Recognise medications used in the management of Parkinson’s disease and understand their mechanism of action and key side effects
Total time:
60 minsNumber of students:
1-2Grade of students:
3rd to 5th year medical studentsCreated by:
Dr Charlotte HaydenUploaded:
27th August 2020Last updated:
27th August 2020Patient, pen, paper, neurological examination kit
none
Take a focused history from a patient with Parkinson’s disease or symptoms suggestive of possible Parkinson’s disease.
It is likely that the patient may have been admitted to hospital with a condition related or unrelated to their Parkinson’s disease (e.g. pneumonia), as opposed to a new presentation of Parkinson’s disease – therefore you should explore their presenting condition in detail, before asking in more detail about the Parkinson’s-like symptoms they have. Include past medical history, drug history, social history, family history – remember to ask appropriate questions to assess for and/or exclude other causes of parkinsonism.
Perform a focused neurological examination of the patient, looking for signs of Parkinsonism and any other examination(s) which may be relevant to their presenting condition.
Document your findings in a systematic manner. You may want to use a local clerking proforma or have a look at this useful summary from Geeky Medics.
Write down 3-5 key differential diagnoses, with the most likely at the top. From this list, suggest one or two key features from the history and/or examination that makes each more and less likely.
Next, consider the differential diagnoses for the patient’s neurological symptoms/signs. Is this likely to Parkinson’s disease or are there any other diagnoses you have considered?
Consider:
What is the difference between the term parkinsonism and Parkinson’s disease?
What are the key symptoms and signs of parkinsonism?
Are there any other less common signs and symptoms of parkinsonism?
Name as many conditions as you can that may present with parkinsonism.
Considering the diagnoses for the patient’s neurological symptoms/signs you have suggested above, what investigations would be useful in confirming and differentiating between diagnoses?
Consider bedside tests, blood tests, urine tests, x-ray, further imaging and any specialist tests.
Find the patient’s most recent CT head. See if you can identify key structure including:
frontal lobe
parietal lobe
temporal lobe
occipital lobe
lateral ventricles
cerebellum
internal capsule
basal ganglia
If the patient has not had a previous CT head, use this example from radiopedia.org. You can check your answers here.
If the patient you have seen has a diagnosis of Parkinson’s disease, find their medication chart. Identify any drugs that have been started for treatment of Parkinson’s disease. Using the BNF (online version available here) look them up and make a note of their mechanism of action.
You may wish to remind yourself of the pathophysiology of Parkinson’s disease using the resources below.
Consider:
What are the common side effects of Parkinson’s drugs and why?
How might these side effects be avoided or managed?
Why is it important for patients with Parkinson’s disease to get their medications on time?
What alternative options are there for patients with Parkinson's disease if they cannot take their usual medications?
You may wish to look up local or national guidelines for the management of Parkinson’s disease in patients who are nil-by-mouth. The Parkinson's UK charity have some good resources available here.
Highlight three key things you have learned today. Summarise them on a post-it note and keep it somewhere you will find in a week or two.
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